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Clinical Experience of Continuous Epidural Analgesia Using Baxter $Infusor^{(R)}$ (Baxter $Infusor^{(R)}$를 이용한 경막외 진통제 지속 주입)

  • Bae, Sang-Chull;Lee, Jang-Won;Kim, Ill-Ho;Song, Hoo-Bin;Park, Wook;Kim, Sung-Yell
    • The Korean Journal of Pain
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    • v.4 no.2
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    • pp.127-132
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    • 1991
  • Recently a non-electronic, disposable and portable infusor(Baxter infusor with patient control module, Baxter health care Co., Deerfield IL 60015 USA: BI $\bar{c}$ PCM) has been developed that will deliver both a continuous drug infusion as well as allow the patient to deliver extra doses of medication on a demand basis under predetermined limitation of analgesics. Patients may also not require as high analgesic dose rate to control pain when the acceptable and tolerable level of pain relief can be maintained by this device. From April l99l, we have used a total l93 units of BI $\bar{c}$ PCM. These units consisting of two components which one made by a balloon reservoir(capacity 65 ml, flow rate 0.5 ml/hr) to store medication and to regulate the pump power(490 torr), and another two PCMs to regulate additional analgesic administration by patients demand at intervals of 1S minutes and 60 minutes. The dose administered to the patient can be varied by changing the concentration of the infusate within the balloon reservoir. These devices were utilized for the pain control of 44 patients. These patients were divided into two groups. Twenty seven cases had cancer pain and 17 cases had non-cancer pain. The Touhy needle(No. l8 G.) tip was inserted into the epidural space and was used to guide the catheter to the spinal nerve level corresponding to the most painful area. The device was connected to the opposite site of the catheter tip and was filled with 60 ml of mixture solution such as 0.5% bupivacaine 15 ml, morphine HCl 10 mg, trazodone 10 ml, Tridol 3 ml and normal saline 31 ml were administed as the initial dose. When the initial dose was less effective, the next dose could be varied by increasing the concentration of bupivacaine, by adding more morphine (5~10 mg), and by reducing the volume of normal saline. Using these modules of drug self administration, we experienced the following: 1) Improvement of patient's self titration of analgesic requirement was provided. 2) The patients anxiety with pain recurrence resulting from delays in administering pain control medication was decreased significantly. 3) The working load accompanying with the single bolus injection as the usual method was reduced remarkably. 4) There was urinary retention in 5 cases and pruritus in 4 eases which developed as side effects but respiratory depression and vomiting was not encountered in a single case.

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Analysis of the efficiency of natural ventilation in a multi-span greenhouse using CFD simulation (CFD 시뮬레이션을 이용한 연동형 온실 내 자연환기의 효율성 분석)

  • Short, Ted H.
    • Journal of Bio-Environment Control
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    • v.8 no.1
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    • pp.9-18
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    • 1999
  • Natural ventilation in a four and one-half span, double polyethylene commercial greenhouse was investigated with actual data collected at Quailcrest Farm near Wooster, Ohio. Moreover, a computational fluid dynamics (CFD) numerical technique, FLUENT V4.3, was used to predict natural ventilation rates, thermal conditions, and airflow distributions in the greenhouse. The collected climate data showed that the multi-span greenhouse was well ventilated by the natural ventilation system during the typical summer weather conditions. The maximum recorded air temperature difference between inside and outside the greenhouse was 3.5$^{\circ}C$ during the hottest (34.7$^{\circ}C$) recorded sunny day; the air temperatures in the greenhouse were very uniform with the maximum temperature difference between six widely dispersed locations being only 1.7$^{\circ}C$. The CFD models predicted that air exchange rates were as high as 0.9 volume per minute (A.C. .min$^{-1}$ ) with 2.5m.s$^{-1}$ winds from the west as designed.

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The Properties of Flow and Compressive Strength of Mortar According In Replacement Ratio of Rapidly-Chilled Steel Slag Pine Aggregate (급냉 제강 슬래그 잔골재 대체율에 따른 모르타르의 유동성 및 압축강도 특성)

  • Cho Sung-Hyun;Kim Jin-Man;Kim Moon-Han;Han Ki-Suk
    • Journal of the Korea Concrete Institute
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    • v.17 no.1 s.85
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    • pp.77-84
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    • 2005
  • The steel slag, a by-product which is produced by refining pig iron during the manufacture of steel, is mainly used as road materials after aging. It is necessary to age steel slag for long time in air because the reaction with water and free-CaO in steel slag could make the expansion of volume. This problem prevents steel slag from being used as aggregate for concrete. However, steel slag used in this study was controled by a air-jet method which rapidly cools substance melted at a high temperature. The rapidly-chilled method would prevent from generation of free-CaO in steel slag. This study dealt with the influence of the using rate of rapidly-chilled steel slag on flow, dosage of SP, W/C ratio, and strength of mortar by statistical experimental design. Also, the results of this experiment were approved by statistical analysis methods, such as analysis of variance and F-testing. As results of F-testing, this paper proved at $1\%$ level of significance that the more the using rate of rapidly-chilled steel slag increased, the more this affected the enhancement of flow, the decrease of dosage of SP and W/C ratio, and the development of compressive strength. Also, considering the fluidity and compressive strength of mortar, it is desirable to use $75\%$ of rapidly-chilled steel slag for river sand.

Estimation of Air Void System and Permeability of Latex-Modified Concretes by Image Analysis Method (화상분석법을 이용한 라텍스개질 콘크리트의 공극 구조와 투수성의 상관성 분석)

  • Jeong Won-Kyong;Yun Kyong-Ku;Hong Seung-Ho
    • Journal of the Korea Concrete Institute
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    • v.17 no.5 s.89
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    • pp.695-702
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    • 2005
  • It is known that latex-modified concretes were increased their durability and permeability by added latex. The purpose of this study was to analysis the air void systems in latex-modified concretes using a reasonable and objective image analysis method with main experimental variables such as water-cement ratios, latex contents(0%, 15%) and cement types(ordinary portland cement, high-early strength cement and very-early strength cement). The results are analyzed spacing factor, air volume after hardened, air distribution and structure. Also, air void systems and permeability of latex-modified concretes were compared with correlation. The results are as follows; The same w/c ratio LMC showed better air entraining effect than OPC with AE water reducer. The VES-LMC showed that the number of entrained air below $100{\mu}m$ increased more than four times. In the HES-LMC, micro entraining air having range from 50 to $500{\mu}m$ increased above 7 times without antifoamer. Though spacing factor was measured low, latex-modified concretes were showed that permeability was good. It is considered that air void system does not have an effect on the property of latex-modified concretes but latex film is more influenced in the their durability.

On the Spectral Efficient Physical-Layer Network Coding Technique Based on Spatial Modulation (효율적 주파수사용을 위한 공간변조 물리계층 네트워크 코딩기법 제안)

  • Kim, Wan Ho;Lee, Woongsup;Jung, Bang Chul;Park, Jeonghong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.20 no.5
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    • pp.902-910
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    • 2016
  • Recently, the volume of mobile data traffic increases exponentially due to the emergence of various mobile services. In order to resolve the problem of mobile traffic increase, various new technologies have been devised. Especially, two-way relay communication in which two nodes can transfer data simultaneously through relay node, has gained lots of interests due to its capability to improve spectral efficiency. In this paper, we analyze the SM-PNC which combines Physical-layer Network Coding (PNC) and Spatial Modulation (SM) under two-way relay communication environment. Log-Likelihood Ratio (LLR) is considered and both separate decoding and direct decoding have been taken into account in performance analysis. Through performance evaluation, we have found that the bit error rate of the proposed scheme is improved compared to that of the conventional PNC scheme, especially when SNR is high and the number of antennas is large.

Inspecting Stablity of DSM method with Grouting on Tunnel Face using Chamber Test and Numericlal Analysis (토조실험과 수치해석을 이용한 막장면 그라우팅 DSM공법의 안정성 검토)

  • Kim, Young-Uk;Park, Young-Bok;Kim, Li-Sak;Kim, Nak-Kyeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.3
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    • pp.677-683
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    • 2016
  • In urban areas, underground tunnel construction sites have spread widely to accommodate rapidly increasing traffic volume along with a high-degree economic growth. Earth tunneling might be adapted frequently for the underground space securing, and various tunneling methods have been developed to stabilize the tunnel face and crown. Among them, the DSM (divided shield method) is gaining popularity for its enhanced stability and construction efficiency. This method has its foundation from the Messer Shield method, which is one of the trenchless special tunneling methods. This study examined the effects of face reinforcement on construction the sequence through a large scale soil chamber test and numerical analyses. The chamber has a size of a 1/2 scale of the real tunnel. Surface settlements were measured according the tunneling process. Commercially available software, MIDAS GTS, was used for numerical analysis and its result was compared with the values obtained from the chamber test. The results of the study show that both settlements of the embanked soils and the stress of the tunnel girder are located within the safe criteria. Overall, this study provides basic data and the potential of using a reinforced tunnel face to enhance DSM applications.

An Index Allocation Method for the Broadcast Data in Mobile Environments with Multiple Wireless Channels (멀티무선채널을 갖는 모바일 환경에서 브로드캐스트 데이타를 위한 인덱스 할당 방법)

  • 이병규;정성원;이승중
    • Journal of KIISE:Information Networking
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    • v.31 no.1
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    • pp.37-52
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    • 2004
  • Broadcast has been often used to disseminate the frequently requested data efficiently to a large volume of mobile units over a single or multiple channels. Since the mobile units have limited battery power, the minimization of the access time for the broadcast data is an important problem. There have been many research efforts that focus on the improvement if the broadcast techniques by providing indexes on the broadcast data. In this paper, we studied an efficient index allocation method for the broadcast data over multiple physical channels, which cannot be coalesced into a single high bandwidth channel. Previously proposed index allocation techniques either require the equal size of index and data or have a performance degradation problem when the number of given physical channels is not enough. These two problems will result in the increased average access time for the broadcast data. To cope with these problems, we propose an efficient tree- structured index allocation method for the broadcast data with different access frequencies over multiple physical channels. Our method minimizes the average access time for the broadcast data by broadcasting the hot data and their indexes more often than the less hot data and their indexes. We present an in-0e0th experimental and theoretical analysis of our method by comparing it with other similar techniques. Our performance analysis shows that it significantly decrease the average access time for the broadcast data over existing methods.

Simultaneous Analysis of Bangpungtongseong-san and Its Antioxidant Effect (방풍통성산의 동시분석 및 항산화 효능 연구)

  • Seo, Chang-Seob;Kim, Ohn Soon;Shin, Hyeun-Kyoo
    • Herbal Formula Science
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    • v.21 no.2
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    • pp.133-143
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    • 2013
  • Objectives : We carry out the simultaneous quantification for quality control of four components in Bangpungtongseong-san (BPTSS) sample. In addition, we assessed the antioxidant effects of BPTSS sample. Methods : The used column for separation and analysis of four compounds was Luna C18 column and column oven temperature was maintained at $40^{\circ}C$. The mobile phase for simultaneous determination consisted of two solvent systems, 1.0% acetic acid in water and 1.0% acetic acid in acetonitrile. High performance liquid chromatography-photodiode array (HPLC-PDA) method for analysis was performed at a flow rate of 1.0 mL/min with PDA detection at 254 and 280 nm. The injection volume was 10 ${\mu}L$. The antioxidant activities of BPTSS were evaluated by measuring free radical scavenging activities on 2,2'-Azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) and 1-1-diphenyl-2-picrylhydrazyl (DPPH). The inhibitory effects on low-density lipoprotein (LDL) oxidation were evaluated by the formation of thiobarbituric acid relative substances (TBARS) and relative electrophoretic mobility (REM). Results : Calibration curves were acquired with $r^2{\geq}0.9999$. The values of limit of detection (LOD) and quantification (LOQ) were 0.06-0.29 ${\mu}g/mL$ and 0.20-0.98 ${\mu}g/mL$, respectively. The amounts of geniposide, liquiritin, baicalin, and glycyrrhizin in BPTSS were 5.06, 7.33, 27.56, and 7.81 mg/g, respectively. The BPTSS showed the radical scavenging activity in a dose-dependent manner. The concentration required for 50% reduction (RC50) against ABTS and DPPH radicals were 72.51 ${\mu}g/mL$ and 128.49 ${\mu}g/mL$. Furthermore, GMGHT reduced the oxidation properties of LDL induced by CuSO4. Conclusions : The established HPLC-PDA method will be helpful to improve quality control of BPTSS. In addition, BPTSS has potentials as therapeutic agent on anti-atherosclerosis.

Development of Multidimensional Analysis System for Bio-pathways (바이오 패스웨이 다차원 분석 시스템 개발)

  • Seo, Dongmin;Choi, Yunsoo;Jeon, Sun-Hee;Lee, Min-Ho
    • The Journal of the Korea Contents Association
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    • v.14 no.11
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    • pp.467-475
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    • 2014
  • With the development of genomics, wearable device and IT/NT, a vast amount of bio-medical data are generated recently. Also, healthcare industries based on big-data are booming and big-data technology based on bio-medical data is rising rapidly as a core technology for improving the national health and aged society. A pathway is the biological deep knowledge that represents the relations of dynamics and interaction among proteins, genes and cells by a network. A pathway is wildly being used as an important part of a bio-medical big-data analysis. However, a pathway analysis requires a lot of time and effort because a pathway is very diverse and high volume. Also, multidimensional analysis systems for various pathways are nonexistent even now. In this paper, we proposed a pathway analysis system that collects user interest pathways from KEGG pathway database that supports the most widely used pathways, constructs a network based on a hierarchy structure of pathways and analyzes the relations of dynamics and interaction among pathways by clustering and selecting core pathways from the network. Finally, to verify the superiority of our pathway analysis system, we evaluate the performance of our system in various experiments.

Evaluation of NOx Removal Efficiency of Photocatalytic Concrete for Road Structure (도로구조물 적용을 위한 광촉매 콘크리트의 질소산화물(NOx) 제거효율 평가)

  • Kim, Young Kyu;Hong, Seong Jae;Lee, Kyung Bae;Lee, Seung Woo
    • International Journal of Highway Engineering
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    • v.16 no.5
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    • pp.49-58
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    • 2014
  • PURPOSES : In areas of high traffic volume, such as expressway across large cities, the amount of nitrogen oxides (NOx) emitted into the atmosphere as air pollution can be significant since NOx gases are the major cause of smog and acid rain. Recently, the importance of NOx removal has arisen in the world. Titanium dioxide ($TiO_2$), that is one of photocatalytic reaction material, is very efficient for removing NOx. The NOx removing mechanism of $TiO_2$ is the reaction of solar photocatalysis. Therefore, $TiO_2$ in road structure concrete need to be contacted with ultraviolet rays (UV) to be activated. In general, $TiO_2$ concretes are produced by replacement of $TiO_2$ as a part of concrete binder. However, considerable portion of $TiO_2$ in concrete cannot contact with the pollutant in the air and UV. Therefore, $TiO_2$ penetration method using the surface penetration agents is attempted as an alternative in order to locate $TiO_2$ to the surface of concrete structure. METHODS : This study aimed to evaluate the NOx removal efficiency of photocatalytic concrete due to various $TiO_2$ application method such as mix with $TiO_2$, surface spray($TiO_2$ penetration method) on hardened concrete and fresh concrete using surface penetration agents. The NOx removal efficiency of $TiO_2$ concrete was confirmed by NOx Analyzing System based on the specification of ISO 22197-1. RESULTS : The NOx removal efficiency of mix with $TiO_2$ increased from 11 to 25% with increasing of replacement ratio from 3 to 7%. In case of surface spray on hardened concrete, the NOx removal efficiency was about 50% due to application amount of $TiO_2$ with surface penetration agents as 300, 500 and 700g/m2. The NOx removal efficiency of surface spray on fresh concrete due to all experimental conditions, on the other hand, which was very low within 10%. CONCLUSIONS : It was known that the $TiO_2$ penetration method as surface spray on hardened concrete was a good alternative in order to remove the NOx gases for concrete road structures.