• Title/Summary/Keyword: High-pressure experiment

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Pulsatility Estimation of a Pulsatile Decellularizing Device for the Fabrication of Organ Scaffold (생체장기용 지지체 제작을 위한 박동형 탈세포화 장치의 박동성 평가)

  • Kim, Dong Sun;Yang, Se-Ran;Park, Sung Min;Choi, Seong Wook
    • Journal of Biomedical Engineering Research
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    • v.38 no.2
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    • pp.62-73
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    • 2017
  • To identify a solution for the restricted availability of healthy lungs and the high risk of immune rejections following organ transplantation, tissue engineering techniques for culturing lungs have been studied by many research groups. The most promising method for culturing lungs is the utilization of a bio-scaffold that was prepared using harvested organs from human donors or other animals by removing their original cells. In this study, a pulsatile perfusion pump was used to alleviate the cell removal effect with the high fluid-dynamic power of the perfusion stream during the decellularization process, while other conventional studies focused on chemical methods to identify efficient detergents. The purpose of this study was to analyze the developed device by using energy equivalent pressure (EEP), which is an indicator of pulsatility, to understand the characteristics of pulsatile energy transmitted according to the load size by using the artificial model and compare it with the measured EEP. The pulsatility of the device can be estimated with the concept of fluid-dynamic energy during a particular constant time period or fluid-dynamic power represented as EEP and EEP increment. Because the measured EEP of perfusion flow during decellularization can be changed by the amount of fluid leakage and the degree of clogging in the capillary vessels, EEP should be measured to determine whether the decellularization is progressing without problems. The decrement of EEP caused by the high perfusion resistance was observed from some experimental results that were obtained with artificial models. EEP can be used to monitor the decellularization process after analyzing the varying EEP according to the amount of load. It was confirmed that the EEP was maintained at a high level in the experiment using the harvested lungs from 12-13-week-old rats. In addition, it was confirmed that the cell removal time was faster than when continuous perfusion was performed. In this study, pulsatile power delivered to the lungs was measured to monitor the process of cell removal, and it serve as the evidence for efficient decellularization.

Experiments of Micro Jet Injection for Bio-Medical Application (바이오 분야 적용을 위한 마이크로 젯 인젝션 실험)

  • Ham, Young-Bog;An, Byeung-Cheol;Trimzi, Mojiz Abbas;Kim, Jong-Dae;Lee, Gi-Tae;park, Jung-Ho;Yun, So-Nam
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.40 no.10
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    • pp.681-687
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    • 2016
  • It is essential for micro jet injectors in the biomedical sector to operate under high pressure. High pressure injection, however, is accompanied by high volumes. On/Off valves that can be operated at high speeds have been used to address this problem. In this research, piezoelectric actuators which have a response frequency of the order of hundreds of kilohertz were used as the On/Off valve and experiments were applied. Researchers developed a controller to precisely manipulate the piezoelectric valve with various waveforms. They also fabricated five types of nozzles to consider the effect of nozzle type on injection. This allowed researchers to manipulate and confirm factors that can affect the injection volume and force. Results of this experiment have shown how to decrease the injection volume and increase the injection force. and it is predicted that the optimized injection volume and force value can be determined depending on the skin type.

The Role of Fronts on the Vertical Transport of Atmospheric Pollutants II: Vertical transport experiment using MM5 (대기오염물질의 연직 수송에 미치는 전선의 역할 II: MM5를 이용한 3차원 연직 수송 실험)

  • Nam, Jae-Cheol;Hwang, Seung-On;Park, Soon-Ung
    • Atmosphere
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    • v.14 no.4
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    • pp.3-18
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    • 2004
  • Neglecting the vertical transport from the surface, most of the previous studies on the long-range transport of pollutants have only considered the horizontal transport caused by the free atmosphere wind. I used a three dimensional numerical model, MM5 (The fifth generation Penn State Univ./NCAR Mesoscale Model) for the simulation of vertical transport of pollutants and investigated the mechanism of the vertical transport of atmospheric pollutants between planetary boundary layer(PBL) and free atmosphere by fronts. From the three dimensional simulation of MM5, the amount of pollutants transport from PBL to free atmosphere is 48% within 18 hour after the development of front, 55% within 24 hour, and 53% within 30 hour. The ratios of the vertically transported pollutant for different seasons are 62%, 60%, 54%, and 43% for spring, summer, fall, and winter, respectively. The most active areas for the vertical transport are the center of low pressure and the warm sector located east side of cold front, in which the strong upward motion slanted northward occurs. The horizontal advection of pollutants at the upper level is stronger than at the lower level simply because of the stronger wind speed. The simulation results shows the well known plum shape distribution of pollutants. The high concentration area is located in the center and north of the low pressure system, while the second highest concentration area is in the warm sector. It is shown that the most important mechanism for the vertical transport is vertical advection, while the vertical diffusion process plays an important role in the redistribution of pollutants in the PBL.

An Experimental Study on the Toluene Control Characteristics of Biofilter Packed with Compost, Peatmoss and GAC (Compost, Peatmoss, GAC의 복합 메디아로 충전된 Biofilter의 Toluene 제어특성에 관한 실험적 연구)

  • Eom, Yun-Sung;Han, Se-Hyun;Jung, Yong-Won
    • Journal of Korean Society for Atmospheric Environment
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    • v.23 no.3
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    • pp.265-276
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    • 2007
  • The primary objective of this study is to investigate the effect of media on the performance of biofilters. Two types of experiments were carried out in this study. The first type of experiment used a biofilter with the media composed of three different packing materials of compost, peatmoss and GAC(granular activated carbon), whereas the second type used a biofilter with the media composed of compost only. It was found from the two experiments that the biofilter composed of compost, peatmoss and GAC showed better performance than the one composed of compost only with the higher toluene removal efficiency, lower pressure drop, and more uniform media moisture content. In particular, no appreciable media compression occurred for the biofilter composed of compost, peatmoss and GAC, whereas significant media compression took place in the biofilter composed of compost only. As suggested by the other researchers, it is likely that GAC may be responsible for the higher toluene removal efficiency in the case of the biofilter composed of mixed media especially for the early stage of biofiltration due to its adsorption capability of toluene of such high concentration as 300 ppm. It was also regarded that GAC may playa major role in maintaining lower media pressure drop in the case of the mixed media than the media with compost only because of its mechanical strength resisting to the compression. Nonetheless, further refined experiments may need to draw more accurate conclusion. The results of the additional test run using the same mixed media showed that the biofilter system using the mixed media can be consistently operated for more than 100 days very stably despite sudden change in operating conditions of temperature and flow rate.

A Study on the Recreation Carrying Capacity of Lawn Areas in Parks(I) -Estimation of treading times criteria based on the tolerence of the turf to treading pressure- (공원잔디공간의 『레크레이션』 수용능력에 관한 연구(I) -잔디에 미치는 답압의 영향 및 수용능력의 답압회수 기준설정-)

  • 엄붕훈
    • Journal of the Korean Institute of Landscape Architecture
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    • v.20 no.1
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    • pp.53-68
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    • 1992
  • This study was carried out to estimate the recreation carrying capacity of lawn areas in parks. Recreation carrying capacity in this study is composed of two parts, ecological carrying capacity and psychological carrying capacity. As the first part, this paper deals with the treading times criteria based on the tolerence of the turf to treading pressure. The plant material used for this study was Zoysia japonica, and the treading experiment was done in the experimental fields in Kyungju and Suwon, Korea. The major results of the first part of the study are summarized as follow: 1. As shown in annual change of the growth of the turf, The growth of turt grass was represented by the number of leaf. 2. The tolerance to treading was not significantly different by the time of treading treatment. And the tolerance varies depending on growth rate of grasses, which showed significant relationship with precipitations. 3. From the result of different numbers of simulated treading treatment, the damage of the turf was increased by the increase of the frequency of treading. And the damage was very serious within short period(about 20 days) in high frequency(over 20 times/day) of treading treatment. But low frequency(1∼3times/day) of treading shows good effects on the growth of the turf. 4. The criteria of treading number per day for each carrying capacity level are estimated as 7 times/day for optimum carrying capacity, 13 times/day for standard carrying capacity, and 20 times/day for critical carrying capacity.

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Photocatalytic Efficiency of Anatase TiO$_2$Thin Film by Reactive Sputtering (Anatase TiO$_2$박막의 미세조직이 광촉매 효과에 미치는 영향)

  • Choe, Yong-Rak;Kim, Seon-Hwa
    • Korean Journal of Materials Research
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    • v.11 no.7
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    • pp.537-544
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    • 2001
  • Anatase $TiO_2$thin films as a photocatalyst were prepared by the reactive magnetron sputtering process. The $TiO_2$thin films were deposited on Si substrates under the various conditions : oxygen partial pressure, working pressure, sputtering time, and D.C. power. The photocatalystic degradation of $TiO_2$thin film have been studied to examine the contribution of surface morphology and crystallinity. The thin films with a good crystallinity or a rough surface showed a high photocatalytic degradation rate on phenol and E.coli 078 experiment. Compared with that of only UV radiation, the photocatalytic efficiency of $TiO_2$thin film under the UV radiation and the $O_2$ flow increased. We found that the crystallity and the morphology were the important factors on the photocatalytic efficiency of TiO$_2$thin film.

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High Pressure Refueling Method for HCNG Gas Supply (HCNG 가스공급을 위한 고압혼합 충전방안)

  • Kim, Sang-Min;Lee, Joong-Seong;Han, Jeong-Ok;Lee, Yeong-Cheol;Kim, Yong-Cheol;Chae, Jeong-Min;Hong, Seong-Ho
    • Journal of the Korean Institute of Gas
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    • v.18 no.1
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    • pp.25-30
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    • 2014
  • Mixture of hydrogen and natural gas HCNG mixing equipment production and refueling experiment were performed for supply and product. Hydrogen and CNG in 30 : 70 ratio is mixing of HCNG was performed using ratio control. HCNG refueling method was calculated after reading the pressure of tank for full refuel, amount refuel. Both full refuel and amount refuel results mixed ratio 30 : 70 in the error limits of $H_2{\pm}2%$ met the criterion. HCNG composition analysis result in refueling tank using gas chromatography is satisfying the error limits in refuel tank 30 : 70 ratio were confirmed.

An Analytical Study on Characteristics of a Diesel Injection System (디젤분사계의 특성에 관한 해석적 연구)

  • 장영준;박호준;전충환
    • Journal of Advanced Marine Engineering and Technology
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    • v.13 no.4
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    • pp.63-74
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    • 1989
  • It is well-known that the fuel injection system if a diesel engine has taken a more important place in understanding of diesel combustion process with combustion chamber. But a diesel fuel injection system has an assembly of many complex and intricate problems such as the desired rate of injection, secondary injection and injection pump etc., in addition to the atomization for ignition and combustion, the penetration and diestribution for proper utilization of air. The analysis is carried out by simplifing and modeling the injection phenomena and dividing into three parts comprising of fuel injection pump, high pressure pipe and fuel injection nozzle. The purpose of this paper is to describe an analytical simulation of the injection system and to speed up the work of developing injection systems for new engines. The effects of important injection parameters as predicted by the present model are found to be in good agreement with experiment. It can be seen that there is an optimal pipe diameter for maximum quantity injected.

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Characteristics of surface damage with applied current density and cavitation time variables for 431 stainless steel in seawater (431 스테인리스강의 해수 내 적용 전류밀도 및 캐비테이션 시간 변수에 따른 표면손상 특성)

  • Kim, Seong-Jong;Chong, Sang-Ok
    • Journal of Advanced Marine Engineering and Technology
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    • v.38 no.7
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    • pp.883-889
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    • 2014
  • It is generated for cavitation erosion due to the local static boiling by pressure differentials in high speed rotating fluid environment. The cavitation is influenced by various elements such as pressure, velocity, temperature, pH of fluid and medium. In particular, the damage of material is accelerated due to the electrochemical corrosion by $C1^-$ and cavitation erosion due to cavities in seawater. In this paper, hence, it investigated for martensite stainless steel the damage behavior with applied current density and cavitation time in natural seawater solution. Less damage depth at the cavitation condition was observed than static condition as a result of galvanostatic experiment. Furthermore, it was shown that dramatic increase of weightloss, damage rate and damage depth after 3 hour of cavitation test.

Hydrothermal Synthesis of Smectite from Dickite (딕카이트로부터 스멕라이트의 수열합성)

  • Ryu Gyoung-Won;Jang Young-Nam;Bae In-Kook;Chae Soo-Chun;Choi Sang-Hoon
    • Journal of the Mineralogical Society of Korea
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    • v.17 no.3
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    • pp.267-275
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    • 2004
  • A hydrothermal process was used to synthesize dioctahedral smectite from dickite [$A1_2$$Si_2$$O_{5}$ $(OH)_4$], Dickite was previously activated by heating at $800^{\circ}C$ far 4 hours with $Na_2$$CO_3$. After the heat-treatment, $SiO_2$ was added for stoichiometry, The autoclaving was carried out in closed stainless steel vessel (about 1 liter) at the condition of various temperature, pressure, time etc. High quality smectite could be obtaind by heating at $290^{\circ}C$ under the pressure of 60 kgf/$\textrm{cm}^2$ for 48 hours. This experiment reveals that pH of the solution was an important factor and should be maintained at 10 to 11 for the formation of dioctahedral smectite. The synthesized smectite was identified as Na-beidellite by the treatment of ethylene glycol and Greene-Kelly test.