• 한국자기공명학회논문지
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• 제25권2호
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• pp.12-16
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• 2021

Daphnia magna is used as target organism for environmental metabolomics. The metabolome of D. magna was studied with NMR spectroscopy. Most studies used the extract of D. magna, but the reproducibility cannot be obtained using extracted sample. In this study, lyophilized D. magna samples were analyzed with two different ¹H NMR techniques, HR-MAS on intact tissues and solution NMR on extracted tissues. Samples were measured three times using 600 MHz NMR spectrometer. Metabolite extraction required more than twice as many D. magna, but the metabolite intensity was lower in solution NMR. In the spectra of HR-MAS NMR, the lipid signal was observed, but they did not interfere with metabolite profiling. We also confirmed the effect of swelling time on signal intensities of metabolites in HR-MAS NMR, and the results suggest that appropriate swelling should be used in lyophilized D. magna to improve the accuracy of metabolite profiles.

• 한국지반공학회논문집
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• 제38권11호
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• pp.137-147
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• 2022

지하시설물의 정확한 매설위치를 파악하기 위해 다양한 지구물리탐사방법이 사용되고 있고, 정확도를 개선하기 위해 다수의 연구가 진행되고 있다. 본 연구에서는 우주선 뮤온이라는 입자를 활용하여 새로운 개념의 탐사 방법을 통해 지하매설물 탐사 가능성을 분석하였다. 신틸레이터(scintillator)와 광증배관(silicon photomultiplier)을 조합하여 소형 뮤온 검출기 시작품을 제작하고, 뮤온 입자 계수에 대한 보정 작업을 수행하였다. 시작품을 활용하여 모형 토조의 지반두께를 측정하였으며, 실측값과 약 3%의 오차로 실측값에 가까운 값을 추정할 수 있었다. 또한 뮤온 검출기를 지하매설물 탐사용으로 활용하기 위해 토모그래피 해석기술에 대한 이론적 기반을 분석하고, 천정각(zenith angle) 보정 방법을 제시하였다. 연구 결과 뮤온 입자에 의한 탐사는 밀도 그 자체를 고해상도로 해석하는 것이 가능한 기술로써 지하매설물 탐사를 위해 활용 가능할 것으로 판단된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권4호
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• pp.293-299
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• 2022

Purpose: Data on eosinophilic esophagitis (EoE) in South America is scarce. Moreover, no studies are available in Ecuador. We evaluated the clinical, endoscopic, and histological characteristics of Ecuadorian children with EoE. Methods: Medical records of 2,711 children who underwent upper gastrointestinal endoscopy (UGE) between 2009 and 2020 at Hospital Metropolitano de Quito, Ecuador were reviewed. Esophageal mucosal biopsies were obtained from 72 patients and the features of 35 children with EoE were described. EoE was diagnosed when there were more than 15 eosinophils in the esophagus, per high power field. Results: EoE was diagnosed in 35 children (9.4±4.5 years) with a male predominance (74%). Abdominal pain (51.4%) and vomiting (31.4%) were dominant symptoms. A history of allergic diseases was noted in 47.1% of the children, which mainly included allergic rhinitis (37.1%) and atopic dermatitis (11.4%). The most common endoscopic findings were furrowing (82.9%) and edema (74.3%). All patients were initially treated with proton-pump inhibitors (PPIs). Those who did not respond to PPIs received steroids (5.7%) and diet therapy (5.7%), and five patients were referred to an allergist. Clinical and histological resolution was observed in 65% of the patients who underwent a second UGE after 6-8 weeks of PPI. Conclusion: Our study describes the clinical features of pediatric EoE in Ecuador. This is the first retrospective study in Ecuador that describes the clinical, endoscopic, and histological manifestations of EoE in a small pediatric population. Almost half of the children who underwent a biopsy had EoE.

• Advances in aircraft and spacecraft science
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• 제9권5호
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• pp.449-462
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• 2022

Space-telescopes placed in the Sun-Earth second Lagrange point (L2) observe the sky following a scan strategy that is usually based on a spin-precession motion. Knowing which regions of the sky will be more observed by the instrument is important for the science operations and the instrument calibration. Computing sky observation parameters numerically (discretizing time and the sky) can consume large amounts of time and computational resources, especially when high resolution isrequired.This problem becomesmore critical if quantities are evaluated at detector level instead of considering the instrument entire Field of View (FoV). In previous studies, the authors have derived analytic solutions for quantities that characterize the observation of each point in the sky in terms of observation time according to the scan strategy parameters and the instrument FoV. Analytic solutions allow to obtain results faster than using numerical methods as well as capture detailed characteristics which can be overseen due to discretization limitations. The original approach is based on the analytic expression of the instrument trace over the sky. Such equations are implicit and thusrequiresthe use of numeric solversto compute the quantities.In this work, a new and simpler approach for computing one ofsuch quantities(mean observation time) is presented.The quantity is first computed for pure spin motion and then the effect of the spin axis precession is incorporated under the assumption that the precession motion is slow compared to the spin motion.In this sense, this new approach further simplifies the analytic approach, sparing the use of numeric solvers, which reduces the complexity of the implementation and the computing time.

• 한국지형학회지
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• 제17권3호
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• pp.1-16
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• 2010

식물 세포와 조직 사이에 형성된 규산염인 식물규소체는 특히 벼과식물에서 다양한 형태로 많이 산출되고, 분석 결과는 제4기 기후와 환경변화 복원 및 농경활동 가능성을 밝히는데 기여한다. 식물규소체는 물리적, 화학적 풍화에 대한 저항력이 강하며 토양에서 장기간 보존되지만, 제자리에 퇴적되는 특성으로 인하여 연구성과의 적용 공간은 제한된다. 식물규소체는 반복성과 중복성으로 동정이 어렵고, 분류체계도 완성되지 않았으므로 우리나라에서 적용할 수 있는 식물규소체 형태분류를 시도하였다. 식물규소체 분석 결과를 통한 고환경복원은 다양한 분야에서 활발하게 이루어지고 있다. 특히 식물규소체의 기후지시자와 함께 Iph와 Ic 등 기후지수를 이용하여 고해상도의 고기후복원도 가능하다.

• 한국광학회:학술대회논문집
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• 한국광학회 2000년도 하계학술발표회
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• pp.74-75
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• 2000

The past few decades have witnessed the development of very robust technique, known as magneto-optical trap(MOT), for cooling and trapping of neutral atoms using lasers and magnetic fields. This technique can easily produce cooled atoms to a temperature range of nano-kelvin $s^{(1)}$ . These laser cooled and trapped atoms have found applications in various fields, such as ultrahigh resolution spectroscopy, precision atomic clocks, very cold atomic collision physics, Bose-Einstein Condensation, the Atom laser, etc. Particularly, a few isolated atoms of very low temperature are needed in the cavity QED studies in the optical regime. One can obtain such atoms from a MOT using the atomic fountain technique. The widely used technique for atomic fountain is, first to cool and trap the neutral atoms in MOT. And then launch them in the vertical (1, 1, 1) direction with respect to cooling beams, using moving molasses technique. Recently, this technique combined with the cavity-QED has opened an active area of basic research. This way atoms can be strongly coupled to the optical radiation in the cavity and leads to various new effects. Trapping of single atom after separating it from MOT in the high Q-optical cavity is actively initiated presentl $y^{(2.3)}$. This will help to sharpen our understanding of atom-photon interaction at quantum level and may lead to the development of single-atom laser. Our efforts to develop an $^{85}$ Rb-atomic fountain is in progress. (omitted)

• 한국지반공학회논문집
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• 제23권1호
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• pp.51-65
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• 2007

본 논문의 목적은 초음파 탐사 방법을 이용하여 지반내의 불연속 물질을 탐측할 수 있는 고해상도의 시스템을 개발하고 실내에서 적용하는 것이다. 초음파 탐측 방법은 불연속면의 경계면에서 반사되어온 반사파를 탐측하고, 이를 배열하여 불연속면의 존재를 찾는 방법이다. 본 논문은 암반내 초음파의 전달 양상, 최적화된 트랜스듀서의 선택, 데이터 획득, 신호처리 방법, 영상화 기법, 그리고 실내 적용실험을 포함하고 있다. 실내실험은 수평이동장치와 회전이동장치를 이용하여 수행된다. 수중에서 수평이동 및 회전실험 결과, 불연속면의 위치와 크기가 정확하게 평가 되었다. 또한 석고시료에서 회전실험결과 석고 내에 존재하는 균열과 공동이 비교적 정확하게 영상화됨을 알 수 있다. 본 논문은 새롭게 제시된 방법이 암반 불연속면 탐측에 매우 경제적이고 효과적인 방법이 될 수 있음을 보여준다.

• Journal of Korean Neurosurgical Society
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• 제66권4호
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• pp.418-425
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• 2023

Objective : Deciphering the anatomy of posterior communicating artery (PCoA) aneurysms in relation to surrounding structures is essential to determine adjuvant surgical procedures. However, it is difficult to predict surgical structures through preoperative imaging studies. We aimed to present anatomical structures using preoperative high-resolution three-dimensional proton density-weighted turbo spin-echo magnetic resonance (PDMR) imaging with simple classification. Methods : From January 2020 to April 2022, 30 patients underwent PDMR before microsurgical clipping for unruptured PCoA aneurysms in a single tertiary institute. We retrospectively reviewed the radiographic images and operative data of these patients. The structural relationship described by PDMR and intraoperative findings were compared. Subsequently, we classified aneurysms into two groups and analyzed the rate of adjuvant surgical procedures and contact with the surrounding structures. Results : Correlations between preoperative PDMR predictions and actual intraoperative findings for PCoA aneurysm contact to the oculomotor nerve, temporal uncus, and anterior petroclinoid fold (APCF) reported a diagnostic accuracy of 0.90, 0.87, and 0.90, respectively. In 12 patients (40.0%), an aneurysm dome was located on the plane of the oculomotor triangle and was classified as the infratentorial type. Compared to the supratentorial type PCoA aneurysm, adjuvant procedures were required more frequently (66.7% vs. 22.2%, p=0.024) for infratentorial type PCoA aneurysm clipping. Conclusion : Preoperative PCoA aneurysm categorization using PDMR can be helpful for predicting surgical complexity and planning of microsurgical clipping.

• 대한토목학회논문집
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• 제29권1D호
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• pp.153-160
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• 2009

고해상도 위성영상을 이용한 DEM 자동제작과 관련한 기존연구에 따르면, 토지피복 특성별로 DEM 정확도가 다르게 나타난다는 것을 제시하였다. 따라서 본 연구에서는 토지피복 분류영상을 이용하여 IKONOS Geo레벨 입체영상에서 상관계수 정합을 위한 토지피복 특성별 기준영역 크기 자동선택 방법을 제안하였다. 그리고 기준영역이 큰 지역의 경우, 정합시간 단 축을 위해 기준영역과 검색영역내의 일정간격 화소들만 참여하여 상관계수를 계산하게 하였다. 그 결과, 고정된 기준영역으로 정합한 DEM보다 제안방법으로 구한 DEM의 정확도가 향상되었다. 그리고 실험 대상지 중 경작지에서는 제안방법에 의한 DEM 결과가 수치지도와 ERDAS에 의한 DEM의 결과보다는 오히려 우수한 것으로 판단되어진다.

• 천문학회보
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• 제45권1호
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• pp.43.1-43.1
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• 2020

Cassiopeia A (Cas A) is a young supernova remnant (SNR) where we observe the interaction of SNR blast wave with circumstellar medium. From the early optical studies, dense, slowly-moving, N-rich "quasi-stationary flocculi" (QSF) have been known. These are probably dense CNO-processed circumstellar knots that have been engulfed by the SNR blast wave. We have carried out near-infrared, high-resolution (R=45,000) spectroscopic observations of ~40 QSF, and here we present the result on a QSF knot (hereafter 'Knot 24') near the SNR boundary of Cas A. The average [Fe II] 1.644 um spectrum of Knot 24 has a remarkable shape with a narrow (~8 km/s) line superposed on the broad (~200 km/s) line emitted from shocked gas. The spatial morphology and the line parameters indicate that Knot 24 has been partially destroyed by a shock wave and that the narrow line is emitted from the unshocked material heated/ionized by the shock radiation. This is the first detection of the emission from the pristine circumstellar material of the Cas A supernova progenitor. We also detected H Br gamma and other [Fe II] lines corresponding to the narrow [Fe II] 1.644 um line. For the main clump where we can clearly identify the shock emission associated with the unshocked material, we analyze the observed line ratios using a shock model that includes radiative precursor. The analysis indicates that the majority of Fe in the unshocked material is in the gas phase, not depleted onto dust grains as in the general interstellar medium. We discuss the non-depletion of Fe in QSF and its implications on the immediate progenitor of the Cas A supernova.