• 제목/요약/키워드: High frequency symptom

검색결과 114건 처리시간 0.031초

중증근무력증(重症筋無力症)에 대(對) 임상적(臨床的) 연구(硏究) (The clinical study of Myasthenia Gravis)

  • 채병윤
    • 대한한의학회지
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    • 제17권1호
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    • pp.190-211
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    • 1996
  • Generally the Myasthenia Gravis is classified into two of hereditary factor and acquement. Aquired Myasthenia Gravis was Quite well known to be caused by the autoimmune mechanism. Not in accurateness, on the hereditary, acetylcholine receptor antibody was to be analyzed very high in their parents and brothers. Also Myasthenia Gravis is a chronic disease characterized by voluntary muscle weakness and fatigue. above all, ocular Myasthenia Gravis is characterized clinically by blepharoptosis and external ophthalmoplegia and to be showed abut 90% cases and so oriental medicine can not but deal with myasthenia gravis at blepharoptosis. Accordinglv 20 out patients with Myasthenia Gravis were clinical study and observation as to the sex, age, progress state of MG, blood type, history, main symptom, liking for warm and cool food and tepidity, state of pulse, treatment of acupuncture and administration of oriental medicine etc. The results were as follows. 1. There was investigaed on the frequency of attack for sex, age, oculus dexter, oculus sinister, oculus uterque. Among the 20 patients, the number of female were 60% with 12 cases and male were 40% with 8 cases, therefore it was the rate of 6 : 4. the patients under 10 ages and 40 ages were 20% with 4 cases, 10 ages and 50 ages were 15% with 3 cases, 20, 30, 60 ages were 10% with 2 cases. And then oculus uterque was 90% with 18 cases, oculus sinister was 10% with 2 cases and oculus dexter were none of them. 2. Stage I were 50% with 10 patients, stage $II_A$ were 30% with 6 patients and stage $II_B$ were 20% with 4 patients, on the clinical stage and too class I were 20% with 4, class II were 45% with 9, class III were 35% with 7, in the functional activity the patients with chest heavy were 15% with 3 and hyperthyroidism were 10% with 2. 3. Hospital which patients had used to before came to this hospital were 10 university hospital and 6 local clinic. 4. The duration of disease was from 3 months to 30 years, the patients suffering between 3 months and within 1 year were 25% with 5 cases, 1-2 years were 30% with 6 cases, therefore within 2 years were 55%. 4-5 years were 15%, over 7 years were appeared less than 10%. 5. In the main symptom, all of patients were appeared to be heavy in opening their eyes the patients with blephroptosis were 70% with 14 cases on the oculus uterque, oculus sinisterf and oculus dexter, there were 20% with 4 eases each other in the oculogyation incomplete. visual failing, ophthalmoxerosis, strabismus etc and indigetion, frequency of urine(feel hurt), mild stools(or diarrea), oversensitiveness etc. but in addition, all of the other were 10%. 6. In the distribution of blood type, 0 types were 45% with 9 cases, A types were 25% with 5 cases, B and AB types were 15% each other. 7. For the rates of patients of liking for warm and cool food or tepidity, patients of liking for warm food possess 45% with 9 cases, and cool food possess 35% with 7 and tepidity possess 20% with 4, and then most of patients liking for warm food were females and cool food were much more males than females. 8. Hyunsae(弦細) were 40% with 8 cases, Buhurl(浮滑) were 20% with 4 cases, Hyunsak(弦數) were 15% with 3 cases, and in addition, the others were 10%, among 7 types of pulses. 9. The patients with less than 1 week were 40% with 8 cases, and there were female most of them and over 4 weeks were 20% and 1-2weeks were 15%, in the duration acupuncture treatment. 10. 15 kinds of prescriptions were administrated with oriental medicine from 1 week to 20weeks 1_2 weeks were 25.71% with 9 cases, 3 weeks were 17.14% with 6 cases and 6 weeks were 11.42% with 4 cases and also Gamibaetaugunbitang(加味培土健脾湯) were 28.57% with 10 cases, Gamijeounyongtang(加味正容湯) were 14.28% with 5 cases, Gamibojoongyigitung (加味補中益氣湯), Gamiyinsamyangyoungtung (加味人蔘養榮湯) were 8.57% with 3 cases each other and also Gamisamgitung (加味蔘?湯), Gamisamuloajatung(加味四物五子湯) Gamigoudungum (加味鉤藤飮), etc were applied.

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산후조리원의 표준화 관리 지침을 위한 연구 - 산모와 신생아 관리현황을 중심으로 - (A Study for the Development of Standardized Management Manuel in Sanhujoriwon - Centered on the Management of Women & Newborn -)

  • 정은실;유은광
    • 여성건강간호학회지
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    • 제8권2호
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    • pp.301-313
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    • 2002
  • The purpose of this study was to develop the frame for standardized manual for Sanhujoriwon by finding out the status of the management of women & newborn in Sanhujoriwon, like postpartum care center. The subjects were 95 staffs of 22 Sanhujoriwon agreed on oral consent, in Seoul and Bundang, Korea. Data were collected from Sep. 15 to Oct. 24, 2001. The instrument used for this study was a structured questionnaire consisted of 16 items of general characteristics & educational characteristics about postpartum care, 31 items of degree of management of women's postpartum care (Cronbach's $\alpha$.93 ), 24 items of degree of management of newborn's care(Cronbach's $\alpha$.94 ), 10 items of methods of management of women's postpartum care, 8 items of methods management of newborn's care. The data were analyzed by the SPSS/PC+ program using frequency, percentage, mean, standard deviation, t-test, ANOVA and Pearson correlation coefficient. The results of the study were as follows ; 1. The mean of the degree of management for postpartum women was 4.1. The mean score for the degree of management of general postpartum care for women was 4.00 & traditional postpartum care(Sanhujori) was 4.20. The degree of management of traditional postpartum care was higher than general postpartum care for women. 2. The degree of management for newborn : The mean score for the degree of management of newborn was 4.37. 3.There was a strong positive correlation between general postpartum care and traditional postpartum care($r=.744^{**}$), and postpartum mother care and newborn care($r=.798^{**}$). 4.The basic frame for the management of the women and newborn in Sanhujoriwon. 1) For women: Integrated postpartal care Physical management : Vital sign & BP check, contraction of uterus, form and amount of lochia, management of personal hygiene, management of breast & breast-feeding, management of postpartum exercise, prevention of infection, symptom & sign of high risk and prevention & management of high risk condition; Emotional-psychological management: assessment and management of mother-baby attachment, emotional state; Educational management : education of vaccination schedule, urinary incontinence, rearing infant, breast-feeding ; and Environmental management : temperature, humidity, disinfection, cleaning, light, infection control integrated with 6 principles of Sanhujori. 2) For newborn Physical management : check of vital sign, management of umbilical cord, jaundice, prevention of infection, management of diaper rash; Emotional-psychological management : assessment of sleep, crying, activity, response of mother-baby attachment; and Environmental management : temperature, humidity, disinfection, cleaning, light, infection control integrated with 6 principles of Sanhujori. In conclusion Sanhujoriwon must be health care center for the postpartum women and newborn. Therefore, the establishment of various laws and regulations in such a way to meet the realistic needs of Sanhujoriwon as a health care center for women and infants future health should be done. The standardized management manual based on the results is absolutely required above all.

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양자펌프 억제제에 반응을 보이지 않은 인후두 역류질환 환자에서 고해상도 식도 내압검사의 분석 (Analysis of High-Resolution Manometry Results in LPRD Patients Who Do Not Response to PPI Medication)

  • 이창희;이현섭;진성민;이상혁
    • 대한후두음성언어의학회지
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    • 제23권1호
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    • pp.43-47
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    • 2012
  • Background and Objectives : Laryngopharyngeal reflux disease (LPRD) originates from regurgitation of gastric contents to the laryngopharynx, and it is relatively common disease in otolaryngology. Proton-pump inhibitor (PPI) medication is frequently using treatment method in present time, but controversies exist regarding treatment for it. High-resolution manometry (HRM) system is a newly developed device that using 36 channels and pressure topography plotting program, checking the function and status of esophagus. The aim of this study was to evaluate clinical usefulness of HRM in LPRD patients who do not response to PPI medication. Materials and Method : From July 2009 to July 2010, a total of 99 patients who were suspected LPRD according to symptoms (Reflux Symptom Index >13) and laryngoscopic findings (Reflux Finding Score >7) were retrospectively enrolled in this study. Patients were consisted of 31 men and 68 women, the mean age was 51.8 years, the mean BMI was 22.46. Patients have taken PPI medication for 2 months, after medication, they performed HRM. Comparative analysis was performed with results of the difference in symptoms. Results : In 99 patients, 37 patients (37.4%) show not improvement of LPRD symptoms after PPI medication. Among them, 18 patients (48.6%) showed abnormal findings that were classified as Peristaltic dysfunction (38.9%), Diffuse esophageal spasm (11.1%), Relaxation impairment of LES (11.1%), Achalasia (5.6%), Hypotensive LES (11.1%), Relaxation impairment of UES (11.1%), Nutcracker esophagus (5.6%), Decreased resting pressure (5.6%). Other 62 patients (62.6%) show improvement of LPRD symptoms, 23 patients (37.1%) showed abnormal findings. Most common finding was Peristaltic dysfunction (43.4%) More prevalent abnormal findings of HRM were found in patients who revealed no response to PPI medication (48.6% vs. 37.1%), but it does not reach the statistical significance. Conclusion : Although statistical significances is not showed, the difference observed in the frequency of HRM abnormal finding between response and no response for PPI medication. It has been estimated that HRM may be used to determine differential diagnosis in patients with LPRD. Further studies in lager population containing normal controls will be needed to prove clinical usefulness.

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양자펌프 억제제에 반응을 보이지 않은 인후두 역류질환 환자에서 고해상도 식도 내압검사의 분석 (Analysis of High-Resolution Manometry Results in LPRD Patients who do not Response to PPI Medication)

  • 이창희;이현섭;진성민;이상혁
    • 대한후두음성언어의학회지
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    • 제22권2호
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    • pp.151-155
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    • 2011
  • Background and Objectives : Laryngopharyngeal reflux disease (LPRD) originates from regurgitation of gastric contents to the laryngopharynx, and it is relatively common disease in otolaryngology. Proton-pump inhibitor (PPI) medication is frequently using treatment method in present time, but controversies exist regarding treatment for it. High-resolution manometry (HRM) system is a newly developed device that using 36 channels and pressure topography plotting program, checking the function and status of esophagus. The aim of this study was to evaluate clinical usefulness of HRM in LPRD patients who do not response to PPI medication. Subjects and Method : From July 2009 to July 2010, a total of 99 patients who were suspected LPRD according to symptoms (Reflux Symptom Index >13) and laryngoscopic findings (Reflux Finding Score >7) were retrospectively enrolled in this study. Patients were consisted of 31 men and 68 women, the mean age was 51.8 years, the mean BMI was 22.46. Patients have taken PPI medication for 2 months, after medication, they performed HRM. Comparative analysis was performed with results of the difference in symptoms. Results : In 99 patients, 37 patients (37.4%) show not improvement of LPRD symptoms after PPI medication. Among them, 18 patients (48.6%) showed abnormal findings that were classified as Peristaltic dysfunction (38.9%), Diffuse esophageal spasm (11.1%), Relaxation impairment of LES (11.1%), Achalasia (5.6%), Hypotensive LES (11.1%), Relaxation impairment of UES (11.1%), Nutcracker esophagus (5.6%), Decreased resting pressure (5.6%). Other 62 patients (62.6%) show improvement of LPRD symptoms, 23 patients (37.1%) showed abnormal findings. Most common finding was Peristaltic dysfunction (43.4%) More prevalent abnormal findings of HRM were found in patients who revealed no response to PPI medication (48.6% vs. 37.1%), but it does not reach the statistical significance. Conclusion : Although statistical significances is not showed, the difference observed in the frequency of HRM abnormal finding between response and no response for PPI medication. It has been estimated that HRM may be used to determine differential diagnosis in patients with LPRD. Further studies in lager population containing normal controls will be needed to prove clinical usefulness.

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좌심실기능에 따른 관상동맥우회술의 위험인자 (Risk Factors of Coronary Artery Bypass Grafting According to Ventricular Function)

  • 이헌재;현성렬
    • Journal of Chest Surgery
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    • 제30권9호
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    • pp.885-890
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    • 1997
  • .저자들은 1994년 7월부터 1996년 6월까지 관상동맥우회 술을 시행한 환자 103명을 심실구축력 40%를 기준 으로 심실기능저하군 24명과 심실기능정상군 79명으로 분류하여 환자의 술전,수술변수 18개를 분석하였다. 분석결과 환자의 특성과 수술사망에 영향을 미치는 위험인자에 대해 다음과 같은 결과를 얻었다. 1. 술전 변수중 심비대(p=0.0012), 혈청 크레아티닌 이상(p=0.0166), IABP 실시(p=0.0096)는 기능저하군이 기능 정상군보다 유의하게 높은 빈도를 보였다 2. 수술변수중 기능저하군은 수술적응증에 있어서 심근경색후 협심증의 빈도가 많았고(p=0.00003), 내흉동맥 의 사용은 유의하게 적었다(p=0.00416). 3. 조기사망률은 기능저하군이 기능정상군보다 약간 높았으나 통계적으로 유의한 차이는 없었다(기능저하군 8.3%, 기능정상군 5.1%, p=0.5492). 4. 합병증발생률은 기능저하군 50%(12/24), 기능정상군 33%(79/25)로 두군간에 유의한 차이는 없었다(p=0.1007). 5. 심실기능정상군에서는 연령(고령)(p=0.041)이 수술후 조기사망에 유의한 위험인자로, 심실기능저하군에서 는 연령(p=0.018)외에도 술전 IAaP 실시(p=0.0036), 고콜레스테롤혈증(p=0.00 7), 응급수술(p=0.0036)이 유의 한 위험인자로 작용하였다. 이상의 결과를 통해 심실기능이 저하된 관상동맥질환 환자는 심실기능이 정상인 환자에 비해 많은 술후 조기사망의 위험인자를 갖고있으나.술후 조기사망률과 합병증 발생률은 두 군간에 유의한 차이를 보이지 않 음으로써 심실기능이 저하된 환자에 있어서도 증상의 개선과 장기생존률의 향상을 얻기 위하여 좀더 적극적인 관상동맥우회 술의 실시가 필요할 것으로 생각된다.

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말초성 안면신경마비 경과에 대한 임상적 예후인자 및 신경생리검사의 유용성 분석 (An Analysis of Clinical Prognosis Factors of Peripheral Facial Palsy and the Effects of Electrodiagnostic Test)

  • 안창범;윤현민;장경전;김철홍;정경근;민영광;김수민;김정은;조범규
    • Journal of Acupuncture Research
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    • 제24권4호
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    • pp.209-223
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    • 2007
  • Objectives : Facial Nerve Paralysis is one kind of common diseases and it can be treated by natural therapy and the efficiency of treatment is relatively high. In clinical trial, it is not difficult to find patients who were not completely recovered from Facial Nerve Paralysis, so the symptoms are fixed permanently. This leads many doctors and patients to have interests in the progress and prognosis of the disease, so this study was to analyze clinical prognosis factors and verify the effects of Electrodiagnostic Test. Methods : The 378 subjects were chosen from 987 patients who were suffering from Peripheral Facial Palsy, diagnosed with Bell's palsy and Ramsay Hunt Syndrome and had admission treatment. They got Oriental-Western Medicine Treatment within two weeks after outbreaks of the disease and treated at least over 3 weeks using Oriental-Western Medicine Treatment. Results : 1. There was a significant difference in the results of treatment according to gender, age, types of Facial Palsy, existence of Post Auricular Pain, existence of Labyrinth Symptom, HBGS, and existence of onsets of recovery as clinical prognosis factors of Peripheral Facial Palsy, However, a statistically significant difference was not shown in the results of treatment according to the position of Facial Palsy(left or right), existence of a relapse, and diabetes, hypertension. 2. As a result of overall treatment, 77.2% of patients were recovered almost entirely and 22.8% were not, and the quelae of incomplete recovery were Synkinesis, facial contracture, facial spasm, crocodile tears and scheroma in order of frequency. 3. The results of electrodiagnostic test represented useful correlation to predict the final effects of treatment. Conclusion : Based on the above results, the prognosis factors, the degree of recovery, and the sequelae of incomplete recovery were analysed and the effects of electrodiagnostic test was verified.

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식이섬유의 섭취가 만성 기능성 변비에 미치는 영향 (Effects of Fiber Supplements on Functional Constipation)

  • 김지영;김오연;유현지;김태일;김원호;윤영달;이종호
    • Journal of Nutrition and Health
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    • 제39권1호
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    • pp.35-43
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    • 2006
  • This study aimed to evaluate the effect of dietary fiber supplementation with snack type on functional constipation. We conducted a double blind case-control study with 3 groups; placebo, low dose group (LD: insoluble fiber 7 g/d + soluble fiber 1.2 g/d) and high dose group (HD: insoluble fiber 14 g/d + soluble fiber 2.4 g/d) , which were randomly assigned out of subjects with functional constipation, defined by modified Rome II criteria. We measured anthropometric parameters and evaluated the bowel movement frequency, stool type, straining, sense of complete evacuation, abdominal discomfort/pain, abdominal inflation, relief and colon transit time before, during the supplementation. Both LD and HD groups had significant improvement in straining, sense of complete evacuation and satisfactory relief compared with placebo group (p < 0.05). When subdivide by baseline colon transit time (less than 24 hrs/ 24 hrs or more and less than 72 hrs / 72 hrs or more), only HD group had significantly improvement; colon transit time recovered near by 24 hrs in subjects of 'less than 24 hrs' (from $7.57{\pm}1.40$ hrs to $25.2{\pm}3.91$ hrs, p < 0.01) and reduced in those of '24hr or more and less than 72 hr' (from $47.0{\pm}3.36$ hrs to $31.3{\pm}4.31$ hrs, p < 0.01) and '72 hr or more' (from $106.7{\pm}10.7$ hrs to $85.0{\pm}13.1$ hrs, P < 0.05) subjects. Particularly, positive effect of fiber supplementation on straining and sense of complete evacuation in test groups seemed to be greater in subjects of '24 hrs or less' and '24 hrs or more and less' than 72 hrs' than those of '72 hrs or more'. In conclusion, subjects with functional constipation, particularly those having colon transit time less than 72 hrs can significantly improve, at least in part, symptom related to constipation by fiber supplementation of snack type without serious side effects.

소아에서 진단된 다발성 저음영 결절 형태를 보인 간흡충증 1례 (A Case of Clonorchis Sinensis with Multiple Low Echogenic Nodules in a Child)

  • 황영준;한만용;하두회
    • Pediatric Infection and Vaccine
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    • 제8권1호
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    • pp.123-128
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    • 2001
  • 한국은 간흡충증의 집중유행지역이고 성인에서의 간흡충증과 합병증의 보고는 많이 있었으나 소아의 경우 보고가 없었다. 본 증례는 8세 소아의 대변검사에서 충란을 발견하여 간흡충증을 진단하였다. 방사선 검사 소견에서는 이전에 보고된 전형적인 간흡충증의 방사선 소견과는 달리 간내 말초담도계의 확장 없이 간실질에 다발성의 저음영 결절과 간문맥내에 임파선 증식을 보였다. 저자들은 환아의 과거력 및 임상증상과 말초혈액 검사소견 등을 미루어 볼 때, 이러한 소견을 간흡충 감염에서 급성기의 방사선학적 소견이 아닌가 추정하였다. 이에 8세 남아의 대변검사에서 충란을 발견하여 확진하고 praziquantel 경구복용으로 치유한 1례를 보고하는 바이다.

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일개 대학 교직원 집단에서 고혈압의 위험요인으로서의 평소 한열 예비 연구 (Preliminary Study on Usual Cold or Heat as a Risk Factor for Hypertension in an University Faculty)

  • 정경식;김윤영;백영화;장은수
    • 동의생리병리학회지
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    • 제33권4호
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    • pp.226-232
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    • 2019
  • This study was aimed to reveal that the usual cold or heat state was associated with hypertension and could be a risk. We emailed educational personnel in D university to join this study and 182 subjects participated in from March to December in 2016. The usual cold or heat diagnosis was conducted by two experts who had over 10 years expertise. The blood pressure was measured from the subjected after 10 minute rest with Jawon medical device. The hypertension was diagnosed by the guide of the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The frequency analysis was used in general characteristics, Pearson's Correlation Coefficient analysis was conducted in among continuous variables, and chi-square test was also used between hypertension and cold or heat group. Logistic regression was analyzed to generate the odds ratios (ORs) and 95% confidence interval (CI) for hypertension. The cold score was suggested to have negative association with Body mass Index (BMI, -.374, p<.001), systolic blood pressure (-.333, p<.001), and diastolic pressure (-.261, p<.001). The heat score was analyzed to have positive association with Body mass Index (.413, p<.001), systolic blood pressure (.249, p<.001), and diastolic pressure (.156, p<.001). The distribution of the cold group (35.1%) and non-cold group (64.9%) in hypertension was significantly different (p=0.18). The distribution of the heat group (62.2%) and non-heat group (37.8%) was significantly different (p=0.27). The usual cold was associated with decreased ORs (ORs 0.405, 95% CI=0.191-0.857), and usual heat was associated with increased ORs (ORs 2.327, 95% CI=1.108-4.888). However, after adjusting body mass index, sex, and smoking, the association was not significantly different. It is possible that usual cold or heat associate with hypertension. Further study is needed to show that usual heat may be a independent risk factor for hypertension through follow up design.

식이 단백 유발 직결장염의 임상적 고찰 (Clinical Features of Dietary Protein Induced Proctocolitis)

  • 임선주;김성헌;배상남;박재홍
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제8권2호
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    • pp.157-163
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    • 2005
  • 목 적: 식이 단백 유발 직결장염(DPIPC)은 영아 초기에 발생하여 양호한 경과를 취하는 질환으로 모유나 우유 내 성분에 의한 알레르기 반응이 주요 원인으로 추정되고 있다. DPIPC의 임상적 특징과 자연 경과 및 식이 조절의 필요성에 대하여 알아보고자 하였다. 방 법: 2002년 5월부터 2004년 6월까지 부산대학교병원 소아과에 혈변을 주소로 검사를 받은 영아 중 DPIPC로 진단된 13명을 대상으로 임상적 특징을 후향적으로 분석하였다. 결 과: 남아가 7명(53.8%), 여아가 6명(46.2%)이었고, 혈변이 발생한 시기는 평균 $96.8{\pm}58.8$일이었다. 혈변의 빈도는 평균 $2.6{\pm}2.5$회/일이었고, 혈변의 발현 후 진단까지의 평균 기간은 $35.5{\pm}55.0$일이었다. 환자의 식이는 모유 수유가 9명(69.2%), 인공 영양이 2명(15.4%), 혼합 영양이 2명(15.4%)이었다. 알레르기의 가족력은 1명에서 있었고, 환자에서 다른 알레르기 질환의 동반은 없었다. 어머니의 식이 습관으로 소량의 우유 복용이나 견과류 또는 어패류의 섭취가 각각 3명에서 있었다. 혈액 검사에서 백혈구수가 $10,555{\pm}3,145/mm^3$, 호산구 비율이 $6.3{\pm}3.0%$, 절대 호산구수가 $659.0{\pm}532.2/mm^3$였다. 13명 중 6명에서 대장 내시경 검사를 시행되었고, 전 예에서 직장과 S상 결장의 점막에 국소적인 발적과 소결절형성이 관찰되었다. 이 중 5명에서 대장 조직 검사를 시행했으며, 만성 염증과 음와 농양이 동반된 경우가 3명이었고, 전 예에서 결절성 림프양 증식이 있었다. 광학 현미경으로 400배의 고배율 시야에서 관찰하였을 때, 대장 점막의 호산구의 수는 4예에서 10개 이하였고 1예에서 10~20개였다. 13명 모두 식이의 변화나 약물을 사용하지 않고 혈변은 $58.7{\pm}67.0$일 후에 자연 소실되었다. 결 론: 건강한 어린 영아에서 실 모양 또는 고춧가루를 흩어놓은 듯한 혈변이 있을 때는 DPIPC를 의심해야 하고, 환자나 환자의 어머니에서 식이 변화가 없이도 혈변은 대부분 1세 이전에 소실되며 혈변 이외에 다른 문제를 야기하지 않는다는 점에서 DPIPC 환자나 어머니에게 일률적으로 식이 제한을 하는 것은 재고할 필요가 있다.

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