• Title/Summary/Keyword: High Molecular Component

검색결과 199건 처리시간 0.037초

SPH SIMULATIONS OF BARRED GALAXIES: DYNAMICAL EVOLUTION OF GASEOUS DISK

  • ANN HONG BAE;LEE HVUNG MOK
    • 천문학회지
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    • 제33권1호
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    • pp.1-17
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    • 2000
  • We have performed extensive simulations of response of gaseous disk in barred galaxies using SPH method. The gravitational potential is assumed to be generated by disk, bulge, halo, and bar. The mass of gaseous disk in SPH simulation is assumed to be negligible compared to the stellar and dark mass component, and the gravitational potential generated by other components is fixed in time. The self-gravity of the gas is not considered in most simulations, but we have made a small set of simulations including the self-gravity of the gas. Non-circular component of velocity generated by the rotating, non-axisymmetric potential causes many interesting features. In most cases, there is a strong tendency of concentration of gas toward the central parts of the galaxy. The morphology of the gas becomes quite complex, but the general behavior can be understood in terms of simple linear approximations: the locations and number of Lindblad resonances play critical role in determining the general distribution of the gas. We present our results in the form of 'atlas' of artificial galaxies. We also make a brief comment on the observational implications of our calculations. Since the gaseous component show interesting features while the stellar component behaves more smoothly, high resolution mapping using molecular emission line for barred galaxies would be desirable.

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Effect of methyl alcohol on the morphology and conformational characteristics of silk sericin

  • Lee Gwang Gil;Gwon Hae Yong;Yeo Ju Hong;U Sun Ok;Lee Yong U;Kim Gi Ho;Jo Jong Su;Park Yeong Hwan
    • 한국잠사학회:학술대회논문집
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    • 한국잠사학회 2003년도 제46회 춘계 학술연구 발표회
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    • pp.59-59
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    • 2003
  • Silk sericin (SS) is one of essential components of cocoon filament, comprising granular and high molecular proteins with adhesive and gelatin-like characteristics. Silk fibroin (SF), another main component of cocoon filament, has been investigated by many researchers due to its good physicochenucal properties. Recently, Nam and Park reported that the effect of alcohol addition into the SF solution on the morphology and structural charateristics of SF. (omitted)

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Applications of Gelatin in Food and Biotechnology

  • Yang, Jae-Sung
    • Preventive Nutrition and Food Science
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    • 제2권3호
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    • pp.263-268
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    • 1997
  • Gelatin is a high molecular weight polypeptide derived fro mcollgen, theprimary protein component of animal connective tissues, which include bone, skin and tendon. Gelatin is usually produced from two different sources of raw materials (skins or bones) which are processed in two ways(line or acid). According to this pretreatment, gelatin can be divided into elatin type A(acid) and B(lime). The market is essentially driven by thre demand sectors: food, harmaceuticals(capsules) and photography. Although there is some potential threat in the photography sector, the oher tow sectors are well placed for futher growth.

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Pretargeting : A concept refraining traditional flaws in tumor targeting

  • Bhise, Abhinav;Yoo, Jeongsoo
    • 대한방사성의약품학회지
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    • 제6권1호
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    • pp.53-58
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    • 2020
  • Pretargeting is a two-component strategy often used for tumor targeting to enhance the tumor-to-background ratio in cancer diagnosis as well as therapy. In the multistep strategy, the highly specific unlabeled monoclonal antibodies (mAbs) with the reactive site is allowed to get localized at tumor site first, and then small and fastclearing radiolabeled chelator with counter reactive site is administered which covalently attaches to mAbs via inverse electron demand Diels-Alder reaction (IEDDA). The catalyst-free IEDDA cycloaddition reaction between 1,2,4,5-tetrazines and strained alkene dienophiles aid with properties like selective bioconjugation, swift and high yielding bioorthogonal reactions are emergent in the development of radiopharmaceutical. Due to its fast pharmacokinetics, the in vivo formed radioimmunoconjugates can be imaged at earlier time points by short-lived radionuclides like 18F and 68Ga; it can also reduce radiation damage to the normal cells. Ultimately, this review elucidates the updated status of pretargeting based on antibodies and IEDDA for tumor diagnosis (PET and SPECT) and therapy.

High Correlation between Alu Elements and the Conversion of 3' UTR of mRNAs Processed Pseudogenes

  • An, Hyeong Jun;Na, Dokyun;Lee, Doheon;Lee, Kwang Hyung;Bhak, Jonghwa
    • Genomics & Informatics
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    • 제2권2호
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    • pp.86-91
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    • 2004
  • Even though it represents $6-13\%$ of human genomic DNA, Alu sequences are rarely found in coding regions. When in exon region, over $80\%$ of them are found in 3' untranslated region (UTR). Pseudogenes are an important component of human genome. Their functions are not clearly known and the mechanism of how they are generated is still debatable. Both the Alu and Pseudogenes are important research problems in molecular biology. mRNA is thought to be a prime source of pseudogene and active research is going on its molecular mechanism. We report, for the first time, that mRNAs containing Alu repeats at 3' UTR has a significantly high correlation with processed pseudogenes, suggesting a possibility that Alu containing mRNAs have a high tendency to become processed pseudogenes. It is known that about $10\%$ of all human genes have been transposed. Transposed genes at 3' UTR without Alu repeat have about two processed pseudogenes per gene on average while we found with statistical significance that a transposed gene with Alu had over three processed Pseudogenes on average. Therefore, we propose Alu repeats as a new and important factor in the generation of pseudogenes.

라만 라이다 시스템을 이용한 라이다 중첩함수 산출 (Retrieval of Lidar Overlap Factor using Raman Lidar System)

  • 노영민;;신동호;이경화
    • 한국대기환경학회지
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    • 제25권5호
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    • pp.450-458
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    • 2009
  • The range-dependent overlap factor of a lidar system can be determined experimentally if a Raman backscatter signal by molecule is measured in addition to the usually observed elastic backscatter signal, which consists of a molecular component and a particle component. The direct determination of the overlap profile is presented and applied to a lidar measurement according to variation of telescope field-of-view and distance between telescope and transmitting laser. The retrieval of extinction coefficient by Raman method can generate high errors for heights below planetary boundary layer if the overlap effect is ignored. The overlap correction method presented here has been successfully applied to experimental data obtained in Gwangju, Korea.

C.I. Acid Red 57의 제조공정 개선에 관한 연구 (Modification of C.I. Acid Red 57 Synthesis Process)

  • Chung, Sang Woo;Kim, Jae Pil
    • 한국염색가공학회지
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    • 제9권5호
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    • pp.75-81
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    • 1997
  • o-Aminobenzene sulfone-N-ethylanilide, the diazo component of C.I. Acid Red 57, is currently being diazotised by the use of nitrosylsulphuric acid because of its high molecular weight and weak basicity. However, this method has many problems such as complicated manufacturing process and discharge of large volume of strong acidic effluent. In this study, the possibility of replacing nitrosylsulphuric acid method by direct method, which is simpler and produces less effluent, has been checked and the optimum process condition was studied. The effect of HCl concentration, the amount of sodium nitrite and particle size of diazo component on diazotisation yield was investigated. The optimum pH condition for coupling reaction was also evaluated.

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Solution Structure of pA2, the Mimotopic Peptide of Apolipoprotein A-I, by NMR Spectroscopy

  • Won, Ho-Shik
    • Bulletin of the Korean Chemical Society
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    • 제32권11호
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    • pp.4016-4020
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    • 2011
  • A number of mimetic peptides of apolipoprotein A-I, a major component for high density lipoproteins (HDL), were screened from the phase-displayed random peptide library by utilizing monoclonal antibodies (A12). A mimetic peptide for A12 epitope against apolipoprotein A-I was selected as FVLVRDTFPSSVCCP(pA2) exhibiting 45% homology with Apo A-I in the BLAST search. Solution structure determination of this mimotope was made by using 2D-NMR data and NMR-based distance geometry (DG)/molecular dynamic calculations. The resulting DG structures had low penalty value of 0.4-0.6 ${\AA}^2$ and the total RMSD of 0.7-1.7 ${\AA}$. The mimotope pA2 exhibited a characteristic ${\beta}$-turn conformation from Val[2] to Phe[8] near Pro[9] residue.

Fabrication of Organic-Inorganic Hybrid Thin Film by Molecular Layer Deposition

  • 한규석;김수환;한기복;성명모
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2010년도 제39회 하계학술대회 초록집
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    • pp.251-251
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    • 2010
  • Organic-inorganic hybrid materials have attracted because of its combined properties, such as flexibility and high electrical performance. In addition, the hybrid materials are expected to have synergic effect which are not shown in just one component. Here, we fabricated organic-inorganic hybrid thin film. Organic-inorganic hybrid thin film have been deposited from diethyl zinc and 1, 2, 4-trihydroxybenzene (THB) by molecular layer deposition (MLD). UV-VIS, Using Infrared spectrum and X-ray photoelectron spectroscopy confirm that Zinc and THB hybrid film (ZnTHB) consist of Zn-O and THB - oxide units and the micro structure and composition of hybrid film. hat the sequential surface reactions of diethyl zinc and ethylene glycol are sufficiently self-limiting and saturating to enable well-controlled MLD growth. Transmission electron microscopy image shows lamination growth of ZnTHB film according to cycle.

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Krill 지질(脂質)의 항산화성(抗酸化性)과 과산화물(過酸化物) 분해작용(分解作用) (Antioxygenic and Peroxide-decomposing Activities of Antarctic Krill Lipids)

  • 이종호
    • 한국식품영양과학회지
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    • 제13권3호
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    • pp.326-333
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    • 1984
  • The oxidation rate of krill lipids is very slow and no peroxides are accumulated even after long storage. By means of various chromatographic techniques and mass spectrophotometry, the primary antioxidant has been identified as ${\alpha}$-tocopherol. The phospholipid fractions did not show any antioxidative activity but peroxide-decomposing properties of total lipids depended upon the phospholipid contents. The peroxide-decomposing activities of phospholipids were due to the presence of polar materials generated during the storage. The most peroxide-decomposing fractions of oxidized krill lecithin by DEAE-cellulose column chromatography was low-molecule fraction (mean molecular weight: 182) and high-molecule fraction (mean molecular weight: 1942) was the next. The separation of peroxide-decomposing properties from low-molecule fraction was achieved by partitioning between chloroform and methanol/water. The methanol/water fraction showed strong peroxide-decomposing activities and main component of this fraction was assumed hydroxyamine compounds derived from choline.

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