• Sleep Medicine and Psychophysiology
• /
• v.22 no.1
• /
• pp.30-34
• /
• 2015

Obesity hypoventilation syndrome (OHS) is characterized by severe obesity, excessive daytime sleepiness, hypoxemia and hypercapnea. Because OHS mimics pulmonary hypertension or cor pulmonale, clinicians should recognize and treat this syndrome appropriately. A 58-year-old female visited the emergency room because of dyspnea. She was obese and had kyphoscoliosis. The patient also experienced snoring, recurrent choking during sleep and daytime hypersomnolence which worsened after gaining weight in the recent year. The arterial blood gas analysis showed she experienced hypoxemia and hypercapnea not only during nighttime but also daytime. We suspected OHS and the patient underwent polysomnography to confirm whether obstructive sleep apnea was present. During the polysomnography test, sleep obstructive apnea was observed and apnea-hypopnea index was 9.2/hr. The patient was treated with bilevel positive airway pressure therapy (BiPAP). After BiPAP for 4 days, hypoxemia and hypercapnia were resolved and she is currently well without BiPAP. We report a case successfully treated with clinical improvement by presuming OHS early in a patient who had typical OHS symptoms, even while having other conditions which could cause hypoventilation.

• Journal of the Korean Dietetic Association
• /
• v.3 no.2
• /
• pp.159-168
• /
• 1997

This study was conducted to examine the effects of Na, K intake and stress level on the blood pressure and urinary excretion of Na, K in the third grade lacto-ovo vegetable male high school students. Twenty-one lacto-ovo vegetarian male high school students were selected, and their physical state, stress level, dietary intake and urinary excretion of Na, K were measured followed by examining the relationship among these factors and blood pressure. The results of the study can be summarized as follows : 1. The average age of the subjects was 17.7 years, and the average score of BMI was 20.4. The average score of Rohrer and blood pressure were 119.1, 112.3/7.5mmHg, each. All of these were in a normal range. Daily calorie intake was 2676.8kcal and Na, K intakes were 152.76mEq, respectively. 2. 71.4% of subjects were susceptible to the disease associated with stress, although there was no significant difference among the salt level, stress and blood pressure. 3. There was significant difference between dietary Na intake ratio, urinary Na excretion and urinary K excretion rate (p<0.001). 4. There was significant difference between systolic blood pressure and BMI/Rohrer score(p<0.01).

• Journal of Applied Biological Chemistry
• /
• v.44 no.3
• /
• pp.113-118
• /
• 2001

Xylose (glucose) isomerase was purified to homogeneity from cell-extracts of Streptomyces chibaensis J-59 via ammonium sulfate precipitation followed by chromatography on DEAE-cellulose, and gel filtration on Sephacryl S-300. The purified enzyme is a homotetramer with a native molecular mass of 180 kDa and a subunit molecular mass of 44 kDa. The amino acid N-terminal sequence of glucose isomerase from S. chibaensis J-59 was determined to be Ser-Tyr-Gln-Pro-Thr-Pro-Glu-Asp-Arg-Phe-Thr-Phe-Gly-Leu. The first 14 amino acids of the N-terminal sequence of the enzyme showed strong analogies with N-terminal sequences of glucose isomerase produced by other Streptomyces spp. The optimum pH and temperature for activity were 7.5 and 85, respectively. The purified enzyme required $Mg^{2+}$, $Co^{2+}$, and $Mn^{2+}$ for the activity, $Mg^{2+}$ being the most effective. The enzyme was not inhibited by $Ca^{2+}$, but was inhibited by $Hg^{2+}$, $Ag^+$, and $Cu^{2+}$. The $K_m$, $V_{max}$, and $k_{cat}$ values of S. chibaensis J-59 isomerase for glucose were 83 mM, 40.9 U/mg, and $1,843min^{-1}$, respectively. In the presence of $Co^{2+}$, cell-free enzymes retained 100% without loss of activities by the heat-treatment at $70^{\circ}C$ for 7 days. The enzyme retained 50% residual activity after heating at $85^{\circ}C$ for 13.5 h, at $90^{\circ}C$ for 126 min. The enzyme is more thermostable than any other glucose isomerases of Streptomyces spp.

• Journal of Ocean Engineering and Technology
• /
• v.24 no.5
• /
• pp.60-66
• /
• 2010

Zinc has a number of characteristics that make it well suited for use as a coating to protecting iron and steel products from corrosion. Its excellent corrosion resistance in most environments accounts for its successful use as a protective coating on a variety of products and in many exposure conditions. The excellent field performance of zinc coatings results from their ability to form dense, adherent films that corrode at a rate that ranges from 1% to 10% of the corrosion rate of ferrous materials, depending on the environment. Recently, EU RoHS and EU ELV prohibited the use of materials that adversely affect the environment, such as Pb, Hg, Cd, and $Cr^{+6}$. In this study, environmentally-friendly, Cr-free solutions (epoxy solution, acrylic solution, and urethane solution S-700) and organic/inorganic solution with Si; LRO-317) were used to evaluate the corrosion resistance of zinc-coated steel subjected to a saltwater spray for 72 hours. The coating of urethane solution (S-700) was best among the three kinds of solution with heat treatment during five minutes at $190^{\circ}F$. Test specimens with S-700 and LRO-317 coating were heat treated in a drying oven at 170, 180, 190, 200, and $210^{\circ}C$ for five minutes. The results show that the optimum corrosion resistance was $190^{\circ}C$ in EGI and $170^{\circ}C$ in HDGI, respectively.

• Journal of Environmental Health Sciences
• /
• v.30 no.1
• /
• pp.41-49
• /
• 2004

Attention Deficit Hyperactivity Disorder (ADHD) is one of the most general childhood problems occurs locally and internationally, but the causes of ADHD are not cleared yet. Therefore, this study tried to examine some parts of the causes of ADHD closely, and finally contribute to the medical treatment of ADHD and its precautionary measures, by measuring and comparing concentration of minerals in hairs of the patients of ADHD and their control group's children. which can analyze the relevance to ADHD and the mineral content in human bodies, and mutual relations between toxic minerals and essential minerals in human bodies. After collection of hairs from 200 children(5 to 7-year-old, boys: 159 girls:41) diagnosed as ADHD by medical specialists based on the standard of DSM-IV diagnosis and their control group's 177 children(boys: 138 girls:39), the mineral concentration of samples was measured through ICP-MS and compared. And correlations between toxic minerals and essential minerals in human bodies among patients group was analyzed. All the toxic minerals(Pb, Hg, Al, Cd, As) of hairs analyzed in the study showed more higher range of concentration in patients group in comparison with their control group. Among them, the concentration of Pb(3.27 $\pm$ 3.82 ppm) and As(0.16 $\pm$ 0.15 ppm) in patients group were significantly high compared to their control group. And in this study Pb among toxic minerals showed negative correlation with Zn(r = -0.43), Mg(r = -0.15) among essential minerals. Cd among toxic minerals showed negative correlation with Zn(r = -0.20) among essential minerals. As among toxic minerals showed negative correlation with Ca(r = -0.14) among essential minerals.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.12 no.3
• /
• pp.93-103
• /
• 2010

The results of comparison and analysis of dynamical features according to Jacquard structure are as follows. Regarding elongation(E) value in tensile property, the value in the direction of course was found to be larger in all Jacquard structure, except floating Jacquard, than the direction of wale. It could be found that, as to bending strength(B) in Bending Property, the value of bending strength in the direction of course smaller in all the textile(structure) except floating than the direction of wale, so that the ability of curve formation is excellent. And in case of floating Jacquard, it showed the smallest value in the direction of course and wale, so that it was interpreted as Jacquard having a soft feel. Blister Jacquard showed the highest value in both directions of course and wale, so that it was evaluated as Jacquard having the hardest touch. With regard to shearing character(G) and shearing hysteresis(2HG) in Shearing Property, Jacquard indicated the lowest value, so it was evaluated as the textile(structure) having high drape the transformation of whose fabric is easy. In addition, normal Jacquard, transfer Jacquard, blister Jacquard showed a high value, so that it could be known they are Jacquards having stiff touch. The study implies that normal Jacquard, bird's eye Jacquard, etc., which well stretch in the direction of a course like tubular Jacquard course, is better to make the margin a little shorter than the basic margin, and Jacquard that well stretches in the direction of wale like ladder's back Jacquard and floating Jacquard is better to make the margin longer and the length shorter than the basic margin.

• The Korean Journal of Financial Management
• /
• v.19 no.2
• /
• pp.233-251
• /
• 2002

본 연구는 우리나라를 대상으로 장단기 스프레드와 신용스프레드가 경기변동에 대해 어떠한 예측력을 갖고 있는가를 살펴보았다. 이를 위해 1991년부터 2001년까지를 분석기간으로 하여 Probit 분석을 통해 금리스프레드와 경기변동과의 시차 및 불황확률을 추정하여 평가해 보았으며, 인과관계 검정을 시도해 보았다. 우선 금리스프레드와 경기변동에 대한 불황확률을 알아보기 위해서 Probit 모형을 이용하여 불황확률을 추정하였다. 그 결과 장단기 금리스프레드 중에서는 5년 만기 1종 국민주택채권수익률-콜금리(HCS)는 3개월, 5년 만기 1종 국민주택채권수익률-1년 만기 금융채수익률(HGS)은 7개월, 5년 만기 1종 국민주택채권수익률-1년 만기 통안증권수익률(HMS)은 9개월의 시차를 보이는 경우가 Pseudo $R^2$ 값이 가장 높게 나타났지만 불황확률을 토대로 경기 호황과 불황 국면을 비교해 본 결과 HMS는 Pseudo $R^2$의 값도 상대적으로 높았을 뿐만 아니라 매우 높은 경기변동 예측력을 보여주었다. HCS와 HGS의 경우에는 IMF 체제 전후의 불황기와 그 이후에 도래한 호황기는 예측력이 높게 나타났으나 1990년대 초반에는 제대로 불황확률을 예측하지 못하는 것으로 나타났다. 또한 3년 만기 회사채수익률-5년 만기 국민주택채권수익률(CHS)와 3년 만기회사채수익률 -3년 만기 금융채수익률(CGS)로 나타낸 신용 스프레드에서는 유의적인 결과를 도출하지는 못하였다. 한편 인과관계에서도 HCS, HGS, HMS 등의 장단기 스프레드는 경기변동에 대하여 일방적 원인변수로 작용하는 것으로 나타나 선행결합관계를 보여주었으나 CHS, CGS 등의 신용스프레드는 경기변동과 어떠한 유의적인 결합관계도 보여주지 못하였다. 따라서 장단기 스프레드는 경기변동을 예측하는데 유용한 정보를 제공하지만 신용스프레드는 경기변동을 예측하는데 도움을 주지 못하는 것으로 나타났다.

• Journal of Preventive Medicine and Public Health
• /
• v.41 no.4
• /
• pp.255-264
• /
• 2008

Objectives: This study adopted a qualitative method to explore the layman's beliefs and experience concerning high blood pressure and its management in order to develop a strategy to increase adherence to proper medical treatment. Methods: Semi-structured interviews that focused on personal experiences with hypertension and its management were conducted with 26 hypertensive patients. The participants were selected according to a BP above 140/90 mmHg (hypertension stage 1), based on the seventh report of the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure (JNC-VII). The interviews lasted for approximately 30 minutes (range: 20-60 minutes). The resulting questions were formulated into open-ended questions. The interview questionnaire was composed 17 items to examine non-adherence to treatment and 19 items to examine adherence to treatment. Results: Most participants recognized that the direct cause of high blood pressure was unhealthy behavior rather than inheritance. Thus, the hypertensive patient believed they could recover their blood pressure to a normal level through removing the direct cause of hypertension (weight reduction, diet, exercise) instead of taking drugs. The reasons for these statements were that the drugs for controlling hypertension are not natural or they are artificial, and they may have side effects, and drugs are not treatment for the root cause of hypertension. Most of the hypertensive patients chose to manage their behaviors as soon as they knew their blood pressure was high. Therefore, we should not divide the subjects into two groups according to their taking drugs or not, but they should be divided into two groups according to their willingness or not to manage their condition. Conclusions: For developing a strategy for an individual approach to hypertension management, we need to develop a client-centered attitude and strategy. That is, we need to tailor our approach to individual cases to avoid generalizations and stereotyping when developing an adherence increasing strategy.

• Journal of Microbiology and Biotechnology
• /
• v.20 no.11
• /
• pp.1546-1554
• /
• 2010

A bacterial strain capable of producing extracellular ${\alpha}$-galactosidase was isolated from a sample of sugarcane industrial waste. Microbiological, physiological, and biochemical studies revealed that the isolate belonged to Bacillus sp. Furthermore, based on a 16S rDNA sequence analysis, the new isolate was identified as Bacillus megaterium VHM1. The production of ${\alpha}$-galactosidase was optimized based on various physical culture conditions. Guar gum and yeast extract acted as the best carbon and nitrogen sources, respectively. The optimum pH was 7.5 and the enzyme remained stable over a pH range of 5-9. The enzyme was optimally active at $55^{\circ}C$ and thermostable with a half-life of 120 min, yet lost 90% of its residual activity within 120 min at $60^{\circ}C$. One mM concentrations of $Ag^2$, $Cu^2$, and $Hg^{2+}$ strongly inhibited the ${\alpha}$-galactosidase, whereas the metal ions $Fe^2$, $Mn^{2+}$, and $Mg^{2+}$ had no effect on the ${\alpha}$-galactosidase activity, and $Zn^{2+}$, $Ni^{2+}$, and $Ca^{2+}$ reduced the enzyme activity slightly. When treated with the B. megaterium VHM1 enzyme, the flatulence-causing sugars in soymilk were completely hydrolyzed within 1.5 h.

• Nuclear Engineering and Technology
• /
• v.34 no.6
• /
• pp.545-552
• /
• 2002

We developed an ultra low background gamma ray spectrometer particularly suitable for experiment which require lower detection limit. The background of a germanium spectrometer is suppressed by applying active and passive shielding technique at the same time. The active shielding devices consist of plastic scintillating plates of 50 mm thick and anti-coincidence electronic system. The shielding is made of 150 mm thick walls of very low activity lead,20 mm with activity of <10 Bq/kg and 130 mm with activity of <50 Bq/kg. The observed background count rates are 1.2 $s^{-1}$ and 0.36 $s^{-1}$ without and with the active shielding, respectively, overall the energy regions from 30 keV to 3 MeV The cosmic ray induced background is suppressed by a rate of 0.8 $s^{-1}$ at the present work. The detection efficiency curve necessary to obtain the radioactivity of environmental samples has been precisely determined on the energy regions from 80 to 2000 keV with a 10$^3$ ml marinelli beaker sample, consisting of the calibrated radionuclides $^{109}$ Cd, $^{57}$ CO, $^{139}$ Ce, $^{203}$ Hg, $^{113}$ Sn, $^{85}$Sr, $^{137}$ Cs, $^{60}$ Co and $^{88}$ Y. Virtues Of the method are demonstrated by measuring the activity of $^{137}$ Cs contained in the powdered milk.