• E2M - 전기 전자와 첨단 소재
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• 제8권3호
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• pp.352-356
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• 1995

Native oxide layer on MCT (HgCdTe) has been grown uniformly in H$\_$2/O$\_$2/ electrolyte through anodic oxidation method. It has been determined that anodic oxidation of HgCdTe in H$\_$2/O$\_$2/ electrolyte proceeds immediately with the input of constant currents without any induction time required for anodic oxideation in KOH electrolyte. Oxide layer with the resistivity of 2*10$\^$10/.ohm.cm and the refractive index of 2.1 suggested the possibility of well matching combination layer with ZnS for MCT MIS device. XPS results indicated that the major components of oxide layer grown in H202 solution is TeO$\_$2/ with the possibility of small amounts of CdTeO$\_$3/.

• 대한치과마취과학회지
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• 제7권2호
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• pp.126-130
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• 2007

Sedation is often indicated for the relief of anxiety for outpatient oral surgery. In combination with local anesthesia, it is safe and effective method of treatment. However, it is not always effective in allowing the physician to complete the planned oral surgery procedure. On occasion, a procedure is left unfinished due to patient combativeness and discomfort and hypertension in spite of increase in sedative doses. Episodic increases in blood pressure were most commonly caused by light anesthesia or sedation and by the patient's experience of pain during treatment. Female patient was 42 years old. blood pressure is 150/90 mmHg. Extraction and implant surgery was done under IV sedation. During seadtion, her blood pressure was increased (200/100 mmHg). Surgery was stopped. She was done monitoring blood pressure. The blood pressure was decreased to 130/90 mmHg. Sedation was failed due to significant hypertension. Blood pressure is seldom increased during sedation but we should evaluate the patient's medical history and know guideline for hypertension crisis.

• Bulletin of the Korean Chemical Society
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• 제35권12호
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• pp.3459-3464
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• 2014

Synthesis and structural characterization of mercury(II) halides and perchlorate complexes (1-4) of bis-$OS_2$-macrocycle (L) are reported. L reacts with mercury(II) chloride and bromide to yield an isostructural 2D coordination polymers with type $[Hg(L)X_2]_n$ (1: X = Cl and 2: X = Br). In 1, each Hg atom which lies outside the cavity is six-coordinate with a distorted octahedral geometry, being bound to four adjacent ligands via monodentate Hg-S bonds and two remaining sites are occupied by two terminal chlorido ligands to form a fishnet-like 2D structure. When reacting with mercury(II) iodide, L afforded a 1D coordination polymer $\{[Hg_2(L)I_4]{\cdot}CHCl_3\}_n$ (3) in which each exocyclic Hg atom is four-coordinate, being bound to two sulfur donors from different ligands doubly bridging the ligand molecules in a head-to-tail mode. The coordination sphere in 3 is completed by two iodo terminal ligands, adopting a distorted tetrahedral geometry. On reacting with mercury(II) perchlorate, L forms solvent-coordinated 1D coordination polymer $\{[Hg_2(L)(DMF)_6](ClO_4)_4{\cdot}2DMF\}_n$ (4) instead of the anion-coordination. In 4, the Hg atom is five-coordinate, being bound to two sulfur donors from two different ligands doubly bridging the ligand molecules in a side-by-side mode to form a ribbon-like 1D structure. The three remaining coordination sites in 4 are completed by three DMF molecules in a monodentate manner. Consequently, the different structures and connectivity patterns for the observed exocyclic coordination polymers depending on the anions used are influenced not only by the coordination ability of the anions but also by anion sizes.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 추계국제학술대회
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• pp.13-13
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• 2003

Methylmercury (MeHg) is a ubiquitous environmental toxicant that can be exposed to humans by ingestion of contaminated food including fish and bread. MeHg has been suggested to exert its toxicity through its high reactivity to thiols, generation of arachidonic acid and reactive oxygen species (ROS), and elevation of intracellular $Ca^{2+}$ levels (［$Ca^{2+}$］$_{i}$). However, the precise mechanism has not been fully defined. Here we show that phosphatidylcholine-specific phospholipase C (PC-PLC) is a critical pathway for MeHg-induced toxicity. MeHg activated the acidic form of sphingomyelinase (A-SMase) and group IV cytosolic phospholipase $A_2$ ($cPLA_2$) downstream of PC-PLC, but these enzymes as well as protein kinase C were not linked to MeHg's toxicity. Furthermore, MeHg produced ROS, which did not cause the toxicity. However, D6O9, an inhibitor of PC-PLC, significantly reversed the toxicity in a time- and dose-dependent manner in MDCK and SH-5YSY cells. Addition of EGTA to culture media resulted in partial decrease of [$Ca^{2+}$］$_{i}$ and partially blocked cell death. In contrast, D609 completely prevented cell death with parallel decreases in diacylglycerol and ［$Ca^{2+}$］$_{i}$. Together, our findings indicated that MeHg-induced toxicity was caused by elevation of ［$Ca^{2+}$]$_{i}$ through activation of PC-PLC. The toxicity was not attributable to the signaling pathways such as $cPLA_2$, A-SMase, and PKC, or to the generation of ROS.

• 대한한방부인과학회지
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• 제25권4호
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• pp.66-80
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• 2012

Purpose: The purpose of this study is to examine acupuncture treatment suggested on the papers of hyperemesis gravidarum(HG) in medicine journals and to establish the future direction. Methods: The papers which were associated with acupuncture and HG published between 2000 and 2012 in Medline were searched. Results: 14 studies met the condition. They were 13 randomized controlled trial (RCT)s and 1 clinical study. 13 studies revealed that acupuncture has efficacies in HG. 1 study was shown to have no statistically significant efficacy. 2 studies revealed that acupuncture was safe treatment, and 1 study revealed that acupuncture was reliable treatment. Conclusions: From the paper research, acupuncture treatment seems to be effective on HG. However, due to the lack sufficient research of HG, it would be necessary to fulfill further study about the period of acupuncture treatment on HG and the selection of acupoint through well-designed study and establish standard of evidence of them.

• 대한예방한의학회지
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• 제5권2호
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• pp.29-39
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• 2001

Purpose: This study was conducted to investigate and compare the growth, blood pressure, and s-cholesterol of urban and rural students in Korea. Methods: April 1999, We examined the students' health of a boys high school and a girls high school in a urban area - Jeonju, Korea.(boys were 317, girls were 343). And we also examined the students' health of a high school in a rural area - Gimje, Korea.(boys were 33, girls wee 36). Height, body-weight, Body Mass Index(BMI)I, blood pressure, and s-cholesterole were checked and compared between two groups. Results and Conclusion: The mean of height in urban students was $165.25{\pm}7.79cm$, and that in rural students was $163.77{\pm}8.72cm$. There was no significant difference stastically between two groups. The mean of body-weight in urban students $(57.78{\pm}10.51kg)$ was significantly higher than that in rural students $(54.71{\pm}10.11kg)$)(p<0.05). The mean of body mass index(BMI) in urban students $(21.12{\pm}3.27kg/m2)$ was significantly higher than that in rural students $(20.30{\pm}2.69kg/m2)$(p<0.05). Obese students $(BMI{\geq}27)$ were 31(4.70%) in urban students, 3(4.35%) in rural students. The mean of systolic blood pressure in rural students $(114.99{\pm}9.50mmHg)$ was significantly higher than that in urban students $(111.89{\pm}12.42mmHg)$(p<0.05) The mean of diastolic blood pressure in rural students$(75.72{\pm}9.90mmHg)$ was very significantly higher than that of urban students $(68.45{\pm}9.40mmHg)$(p<0.001). Hypertensives (${\geq}138/86mmHg\;in\;boys,\;{\geq}130/83mmHg$ in girls) were 28(4.24%) in urban students, 13(18.84%) in rural students. The mean of s-cholesterol in urban students was $174.95{\pm}32.28mg/dL$, and that in rural students was $176.81{\pm}33.18mg/dL$. There was no significant difference stastically between two groups. Hypercholesterolemias (${\geq}198mg/dL$ in boys, ${\geq}212mg/dL$ in girls) were 130(19.70%) in urban students, 14(20.89%) in rural students. These results suggest that there are differences in body weight, BMI, and diastolic blood pressure between urban and rural students and that it is necessary to consider these differences in health examination.

• Journal of Chest Surgery
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• 제35권4호
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• pp.267-273
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• 2002

배경: 저자들은 한국인에 있어서의 급성대동맥박리에 대한 nicardipine의 혈압강하요법에 대한 임상적 유용성을 검토하고자 국내 제4상 임상시험을 실시하였다. 대상 및 방법: 31명의 대동맥 질환 환자에서 시험약의 투여 전후의 수축기 및 이완기 혈압, 심박수 등을 시간변화에 따라 비교 관찰하였다. 시험약식 투여기간은 원칙적으로 3일 이상 14일 이하로 하였으며, 투여 3일째의 평균혈압강하도를 평가하였다. 시험약 사용전 다른 강압제를 사용하고 있었던 경우는 기존 사용약제의 용량을 줄이면서 시험약으로 대체하여 결국 기존 사용약제를 사용하지 않는 것을 원칙으로 하였다. 결과: 연구의 대상이 된 환자는 급성 대동맥 박리가 28명, 대동맥궁류 파열이 2명, 외상성 대동맥 파열이 1명이었다. 연령은 53.9$\pm$14.9(29~89)세였고, 남자가 21명 (67.7%)이었다. 대동맥질환에 기인한 합병증은 대동맥판 폐쇄부전이 7례, 혈성심낭 6례, 급성 신부전 1례, 하지마비 1례, 하지허혈 1례 등이었다. 목표혈압 도달은 15분이내가 16례로 가장 많았고, 15분이상 30분이내가 10명, 30분이상 45분이내가 3명, 45분이상 60분 이내에 도달한 경우가 2명이었다. 관찰기 혈압은 수축기혈압, 이완기혈안, 평균혈압이 각각 147$\pm$23mmHg, 82.3$\pm$18.6mmHg, 104$\pm$18mmHg이었고, 3일째 측정하였을 때 119$\pm$12mrnHg, 69$\pm$grnmHg, 86$\pm$BmmHg로 의미있게 감소하였음을 확인하였다. Nicardipine 투여 종료 시에측정한 수축기 혈압, 이완기혈압, 평균혈압은 각각 119$\pm$ 15mmHg, 70$\pm$ 14mmHg, 86$\pm$ 13mmHg로 3일째 측정한 혈압과 비교하였을 때 의미있는 상승 혹은 하강현상은 관찰되지 않았고 비교적 혈압 하강 상태가 잘 유지되고 있음을 알 수 있었다. 지속적 정맥 투여 중 부작용은 뚜렷하게 관찰할 수 없었다. 결론: 대동맥 박리에 동반된 고혈압에서 nicardipine을 사용하여 만족할만한 혈압하강 효과를 얻었으며, 뚜렷한 부작용이 없이 안전하게 사용할 수 있다는 결론을 내렸다.

• 한국지구과학회지
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• 제22권3호
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• pp.237-247
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• 2001

1980년대 말 시점과 1990년대 말 시점을 비교구간으로 설정하여 서울 한남동지역에 대한 대기중 수은의 농도분포변화양상을 비교해 보았다. 긴 시간 동안 발생원과 소멸원이 지닌 관계의 변화와 같은 영향에 의해, 양 기간대의 농도분포는 절대적 및 상대적 관점에서 모두 뚜렷한 차이를 보여 주었다. 80년대말 시점의 농도가 14.4${\pm}$9.56 ngm$^{-3}$인데 반해, 90년대 말 시점에는 이보다 1/3 가까이 감소한 5.34${\pm}$3.92ngm$^{-3}$를 유지하였다. 두 기간대에 관측된 농도 및 주변환경변수를 여러 가지 주기별로 수은의 농도분포양상을 비교해 보았다. 24시간 주기 또는 계절별로도 양기간대의 농도분포는 뚜렷한 차이를 보여 주었다. 과거 시점에는 낮 시간대에 고농도가 발생하는 현상이 빈번한데 반해, 현 시점에서는 이러한 양상을 확인하기가 어려웠다. 또한 계절적으로 겨울철에 고농도가 집중되는 현상은 과거나 현재나 유사하지만, 과거의 경우 겨울철 고농도가 여타 계절에 비해 확연했던데 반해, 최근의 분석결과는 계절간 차이가 상당 수준 줄어 들었다는 것을 보여 주었다. 이들 자료를 이용하여, 여러 가지 통계분석을 실시한 결과, 양 기간대에 현저하게 차이가 나는 농도분포는 주로 각 기간대별로 수은의 농도를 조절하는 주생성원의 성격이 현저하게 다른 데 따른 가능성이 강할 것으로 사료된다.

• Applied Biological Chemistry
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• 제11권
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• pp.67-76
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• 1969

1968년 7월 30 일에 채취한 축을 시료로하여 12월 3일 까지 저장시험을 한 결과는 1. 현재까지 가장 저장효과가 양호하다고 알려져 있는 CA저장법보다 강압저장법이 우수하였다. 2. 감압도에 있어서는 저감압이 고감압보다 저장효과가 좋으며 본 실험에서 실시한 70cmHg, 60cmHg, 40cmHg 및 20cmHg중에서 20cmHg가 가장 저장효과가 양호하였다. 3. 사과의 표면처리에 따른 효과는 1)저장중의 중량감소를 방지하는데는 Poly-ethylene film포장이 가장 효과적이나 장기저장에 있어서는 과실의 생리장해로 인하여 폐과량이 증가 하였다. 2) Poly-vinyl acetate coating은 과실 원래의 색택유지는 매우 효과적이었으나 특이한 냄새가 생겨서 미각적으로 품위를 저하시켰다. 3) Gibberellin 처리시의 저장효과는 축에서는 전연 없었다. 4. 주요성분의 변화는 1) 전당 및 환원당은 각 저장구에 따라 다소의 차는 있으나 저장 초기에는 증가하고 저장이 계속 됨에 따라 감소하였는데 냉장 20cmHg 감압구(No. 11)에서 증가 및 감소율이 가장 낮았다. 2) 산 및 Vitamin C는 각 저장구 및 처리별에 따라 감소율에 차이는 있으나 저장기간 중 계속 감소하였으며 냉장 20cmHg 감압구(No. 11)에서 그 감소율이 가장 낮았다.

• 센서학회지
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• 제13권2호
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• pp.128-132
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• 2004

Short wave infrared (SWIR) photovoltaic devices have been fabricated from metal organic vapour phase epitaxy (MOVPE) grown n- on p- HgCdTe films on GaAs substrates. The MOVPE grown films were processed into mesa type discrete devices with wet chemical etching employed for meas delineation and ZnS surface passivatlon. ZnS was thermally evaporated from effusion cell in an ultra high vacuum (UHV) chamber. The main features of the ZnS deposited from effusion cell in UHV chamber are low fixed surface charge density, and small hysteresis. It was found that a negative flat band voltage with -0.6 V has been obtained for Metal Insulator Semiconductor (MIS) capacitor which was evaporated at $910^{\circ}C$ for 90 min. Current-Voltage (I-V) and temperature dependence of the I-V characteristics were measured in the temperature range 80 - 300 K. The Zero bias dynamic resistance-area product ($R_{0}A$) was about $7500{\Omega}-cm^{2}$ at room temperature. The physical mechanisms that dominate dark current properties in the HgCdTe photodiodes are examined by the dependence of the $R_{0}A$ product upon reciprocal temperature. From theoretical considerations and known current expressions for thermal and tunnelling process, the device is shown to be diffusion limited up to 180 K and g-r limited at temperature below this.