• The Korean Journal of Physiology and Pharmacology
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• v.27 no.3
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• pp.221-230
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• 2023

Diabetic kidney disease is one of the most serious complications of diabetes. Although diabetic kidney disease can be effectively controlled through strict blood glucose management and corresponding symptomatic treatment, these therapies cannot reduce its incidence in diabetic patients. The sodium-glucose cotransporter 2 (SGLT2) inhibitors and the traditional Chinese herb "Gegen" have been widely used in diabetes-related therapy. However, it remains unclear whether the combined use of these two kinds of medicines contributes to an increased curative effect on diabetic kidney disease. In this study, we examined this issue by evaluating the efficacy of the combination of puerarin, an active ingredient of Gegen, and canagliflozin, an SGLT2 inhibitor for a 12-week intervention using a mouse model of diabetes. The results indicated that the combination of puerarin and canagliflozin was superior to canagliflozin alone in improving the metabolic and renal function parameters of diabetic mice. Our findings suggested that the renoprotective effect of combined puerarin and canagliflozin in diabetic mice was achieved by reducing renal lipid accumulation. This study provides a new strategy for the clinical prevention and treatment of diabetic kidney disease. The puerarin and SGLT2 inhibitor combination therapy at the initial stage of diabetes may effectively delay the occurrence of diabetic kidney injury, and significantly alleviate the burden of renal lipotoxicity.

• The Journal of Internal Korean Medicine
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• v.44 no.4
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• pp.814-822
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• 2023

Objective: This case report details the successful management of bowel perforation through traditional Korean medicine. Often, emergency surgery is required due to potential complications, such as peritonitis. In this case, the patient had previously undergone a total colectomy, making surgical treatment complicated. Methods: The patient revealed persistent abdominal pain and over 20 instances of diarrhea per day. During the course of treatment, which included two hospitalizations and one outpatient visit, acupuncture treatment and herbal medicine were administered. Throughout the treatment period, the intensity of abdominal pain and the frequency of diarrhea gradually decreased. Results: At the end of treatment, a follow-up abdominal computed tomography (CT) scan showed no evidence of perforation. Additionally, blood tests revealed no abnormalities in liver or kidney function, confirming the safety of the treatments.

• Korean Journal of Environment and Ecology
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• v.33 no.6
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• pp.695-707
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• 2019

This study was intended to suggest the appropriate vegetation management methodology by analyzing phytosociology for ecotourism resources. We carried out the classification and interpretation of the vegetation structure and the analysis of the relationship between communities and environmental conditions in Pocheon valley, Mt. Gaya. The vegetation in Pocheon valley was composed of 5 communities: Pinus densiflora-Quercus mongolica community, Quercus serrata-Quercus variabilis community, Larix kaempferi-Quercus serrata community, Pinus densiflora-Castanea crenata community, and Salix gracilistyla-Phragmites japonica community. The Quercus serrata-Quercus variabilis community was further segmented into two types according to the differences of composition species and location of habitats. The methodologies that satisfy both the use of nature for ecotourism resources and the sustentation of natural vegetation are as follows: - maintenance the present vegetation (dominance species) by strictly avoiding artificial management in the tree layer; - maintenance of the existing vegetation structure through the artificial management of the usual vigorous tree species when the species in the shrub layer grow up to the subtree layer; and - continued artificial management to maintain high balanced diversity and evenness of various species in shrub and herb layers.

• Journal of Society of Preventive Korean Medicine
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• v.20 no.1
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• pp.111-124
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• 2016

Objectives : Treatment method using drugs has already been used in Korean medicine for a long time. Moreover, database has been developed and utilized for more efficient management of the treatments that use drugs. Most of such database related to knowledge on drugs is composed of origin, efficacy, temperament, ingredients and examples of application of the standardized drugs. Communication with knowledge information in other specialized areas is also accomplished by using the efficacies and ingredients with the drugs. In this study, we aimed to make data structure of the terminologies that represent the manufacturing process of herbs. However, in spite of the fact that the manufacturing process of the drugs imparts effect on their efficacies and ingredients, details of the manufacturing processes are quite limited to simple text sentences, thereby resulting in substantially lower level of utilization and difficulties in systematic researches on various factors included in the manufacturing processes in comparison to other knowledge on drugs. Methods : This Study extracted the factors necessary in the development of database by executing morphological analysis of the manufacturing process of herbs. Results : The factors are 'Order', 'Act', 'Raw material', 'Tools', 'Supporting materials', 'Intensity', 'Duration Time', 'Interval', 'Focus', 'Repetition Number', 'Untill'. We were able to tell the difference of the manufacturing process with a simple structured query language and the factors. Conclusions : Morphological analysis of medicinal herbs manufacturing Process contributes to standardization with information of the manufacturing process. And it helps to creates a quality management system through the Database.

• Journal of Environmental Science International
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• v.23 no.11
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• pp.1863-1879
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• 2014

This study aims at classifying and interpreting on the shrine forest vegetation located in Jirisan national park affiliated to an ecotone in southern part of Korea, foreseeing a vegetation change based on composition species and dominant species on canopy, and proposing the direction of vegetation management. The shrine forests were classified into the 7 community units as Chamaecyparis obtusa-Cryptomeria japonica afforestation, Pinus densiflora community, Pinus rigida afforestation, Quercus variabilis-Quercus serrata community, Zelkova serrata-Kerria japonica for. japonica community, Phyllostachys bambusoides forest, Camellia japonica community. This research is also expatiated on the analogous results of ordination analysis with phytosociological analysis. The constituents of deciduous broad-leaved forest in the warm temperate zone were appeared in the most vegetations. It emerged less that the constituents of evergreen broad-leaved forest in the warm-temperate zone and deciduous broad-leaved forest in the cold-temperature zone. The life form analyses were made use with the two ways: appearance species in total communities and each community. The species diversity of shrine forests is declined because the high dominances of Sasa borealis and Pseudosasa japonica emerged in the shrub and herb layers. These shrine forests will be succession to Q. variabilis-Q. serrata community as the representative vegetation of deciduous broad-leaved forest in the warm-temperate zone, owing to the temperature rise by global warming, and an evergreen broad-leaved forest will be able to be also formed if a temperate rise will be continued. The one of the artificial management of shrine forests is to consider the introduction of the constituents of evergreen broad-leaved forest in the warm-temperate zone.

• Journal of Environmental Science International
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• v.18 no.1
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• pp.99-111
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• 2009

In this study vegetation structure was monitored focusing on slanting surface of stream for the purpose of developing a management plan and ecological restoration of small stream in Paju. The study was conducted by types of geographical structure, yearly flora, naturalization rate changes, actual vegetation changes, plant community changes. Slope area of small stream in Paju was varied in the slope range of $10{\sim}35^{\circ}$. The survey results of yearly flora showed that 37 species appeared in 2000, 55 species in 2001, 95 species in 2002, and 125 species in 2003. Therefore, the trend of continuous increase of flora each year was observed. In the case of yearly changes of actual vegetation, indigenous wetland herb community including Phragmites communis$(19.99%{\rightarrow}18.42%{\rightarrow}19.60%)$ did not show substantial changes in the area, while the influence of controlled flora such as Humulus scandens$(8.86%{\rightarrow}5.26%{\rightarrow}9.73%)$, and Ambrosia artemisiifolia$(1.06%{\rightarrow}1.43%{\rightarrow}6.93%)$ were increased. The vegetation structure investigated by 18 preset belt-transects also indicated that Phragmites communis and Miscanthus sacchariflorus were maintaining the status or decreasing the population, while the population of Humulus scandens, Ambrosia artemisiifolia, Setaria viridis, and Erigeron canadensis were greatly increased. Our proposal management to restore ecology is as follows: first, preservation and restoration of Phragmites communis landscape; second, restoration of potential stream vegetation community; third, selection and removal of controlled plants.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.1
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• pp.140-150
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• 2002

Introduction: Atopic dermatitis is chronic eczematous dermatosis which is related strongly to a family history of atopic disease and hereditary disposition. Its threshold of itching is low so that severe itching occurs and causes secondary eczema. Adult atopic dermatitis has mostly severe symptoms and progresses to chronic relapsing. Objective: The purpose of this study was to estimate the efficacy of oriental medical treatment and management on chronic adult atopic dermatitis. Subject: We studied 3 patients who visited Dongguk University Gangnam Oriental Hospital Dept. of Dermatol. with chronic adult atopic dermatitis from August 2001 to April 2002 and were observed for over 4 months. Methods: We treated them with herb-medication, acupuncture, negative therapy, aroma therapy, full spectrum visible ray therapy(by carbon arc) and external application(Jaun-go). We used the SCORAD index to assess the severity of atopic dermatitis. Results: There were 3 patients with chronic adult atopic dermatitis we could check for over 4 months by clinical scoring using the SCORAD system. 1. The grades of the severity of atopic dermatitis were lower only by the oriental medical treatments and management. 2. Intensities of relapse cases were lower then before the oriental medical treatments. 3. The secondary treatment term for relapse cases was shorter then the first treatment term after oriental remedies were used. Conclusion: Considering the above results, more study is needed on the chronic relapse cases with adult atopic dermatitis, the factors of increasing seventy of adult atopic dermatitis, the prognostic factors of adult atopic dermatitis, and the clinical interchange of chronic adult atopic dermatitis between oriental medicine and western medicine.

• Korean Journal of Heritage: History & Science
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• v.43 no.1
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• pp.100-117
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• 2010

This study analyzed vegetation structure of natural monuments Koelreuteria paniculata community in search of a conservation and management plan. Plant sociological analysis of Koelreuteria paniculata community indicates that it can be classified into Achyranthes japonica subcommunity and Rhodotypos scandens subcommunity and Trachelospermum asiaticum var. intermedium subcommunity. While Koelreuteria paniculata community of Ahnmyeondo is composed of sub tree layer and herb layer, those of Pohang and Wando are composed of tree layer, Sub tree layer, shrub layer, herb layer. The results of tree vitality analysis showed that those in Ahnmyeondo appeared to be relatively low when compared to those in Pohang and Wando-gun. This can be understood in two different aspects: disease and insects vulnerability due to a relatively simple structure and lack of competitive species, and decreased vitality / natural branch losses due to crown competition arising from high density. The result of soil characteristics analysis showed that soil texture, soil pH, organic matter, $p_2O_5$, exchange positive ion were sufficient for tree growth while total nitrogen was not, so that discretion would be needed for fertilizer application. As there were damages of disease and inscet, but only for 10~15% of the entire area; it still requires consistent preconsideration. The study suggests the management methods for preservation of Koelreuteria paniculata community. First, securing designated areas is necessary in order to minimize environment deterioration due to surrounding development. Especially, for sections with decreased areas, expansion of designated areas through land purchase should also be considered. Second, artificial interference may affect the livestock. Therefore, monitoring of artificial interference is necessary, based on which protection projects must be conducted. Third, from analysis of young plants which influence the maintenance mechanisms of Koelreuteria paniculata community, a decrease compared to the prior year was observed; investigation is needed. Therefore, an active management policy through status examination of livestock such as germination and young plants is necessary.

• Korean Journal of Medicinal Crop Science
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• v.2 no.3
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• pp.227-233
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• 1994

To get a fundamental data fur management of security, validity, Quality, of Paeonia suffruficosa roots as medicinal herb, the content of paeonol, ash, and inorganic components in Moutan Radicis Cortex produced in 8 regions of Korea was investigated from Oct. 1990 to May 1991. The results are summarized as follows: The average content of paeonol was 0.65%. The content of ash was 3.53%, acid-insoluble ash 0.77% in average, both of them were suitable to the standard value as Korean medical herbs. Total nitrogen content was 1.03%, phosphate 0.55%, potassium 0.82%, and calcium 1.50% in average. The content of MgO was 0.21ppm, 325.83ppm in Fe, 1.82ppm in Cr, 3.73ppm in Cu, 18.93ppm in Zn and Mn 21.27ppm, respectively. Especially Hg was not detected in the products of all regions. The average content of Cd was 0.25ppm, Pb 3.09ppm in Moutan Radicis Cortex, so they were estimated suitably to use as medicinal herb.

• Journal of Korean Society of Forest Science
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• v.106 no.2
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• pp.150-168
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• 2017

This study was carried out to compare stand structure in Bihwajin basin Samcheok-si, Gangwon-do, Korea for ten years between 2003 and 2014, in which occurred the east coastal forest fire in 2000. Data were collected from 32 quadrates that followed by the analysis of vegetation classification according to plant sociology, importance value by Mclntosh and Curtise, species diversity and similarity index. In the result of vegetation classification, the vegetation unit decreased from 7 units to 4 units, and the number of species groups changed from 11 to 7. As a result of importance value (IV) changes, IV of Quercus mongolica, Q. serrata and Q. variabilis was increased by 6.8%, 5.2% and 2.9% in the order, respectively. However, that of Pinus densiflora was decreased by 2.8%. That of major planted species such as Castanea crenata, Chionanthus retusa, Prunus armeniaca var. ansu, Acer triflorum and Koelreuteria paniculata was reduced. As a result of species diversity, it was increased from 0.252 to 0.287 in tree layer, from 0.252 to 0.434 in subtree layer, and from 1.293 to 1.333 in shrub layer. But that in herb layer was decreased from 1.745 to 1.646. As a result of similarity index, it was 0.78, 0.65, 0.72 and 0.55 by layers that showed most difference in herb stratum. Considering the results, this study would be applied to the ecosystem diagnose and management of forest fire damaged area similar to the investigated area.