• 생약학회지
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• 제17권4호
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• pp.302-307
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• 1986

Sixteen kinds of Chinese herb drugs using in digestive system have screened for antibacterial activity. It was revealed that all of the herb drug extracts showed antibacterial activity in one or more strains of microbials selected in this experiments. It is noteworthy that Aconitum trilobum showed inhibition of Klebsiella pneumoniae.

• 사상체질의학회지
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• 제13권2호
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• pp.124-137
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• 2001

The purpose of this research was to investigate the inhibitory function among foods and herb drugs. I have gone over literatures of mainly ${\ll}$Eum-Sun-Jung-Yo(飮膳正要)${\gg}$ on the basis of ${\ll}$Dong-Eui-Bo-Gam (東醫寶鑑)${\gg}$ about the properties and flavors of foods and herb drugs. And then I came to get some conclusion as follows. 1. The foods mentioned above are meats, birds, fishes, spices and vegetables. 2. If the foods mentioned above were eaten for a long time, and then it can cause stirring Wind or Qi or Fire inside the body. 3. What it means in the context of the chapter ${\ulcorner}$Sik-Mul-Sang-Ban : Inhibitory Function Among Foods and Herb Drugs(食物相反)${\lrcorner}$ that 'Do not eat the paired foods or herb drugs at a same time' and 'Do not eat the paired foods or herb drugs together for a long time.' 4. The Cold natured foods were not eaten at a same time. 5. The Hot or Warm natured foods were not eaten at a same time. 6. The contrary natured foods were not eaten at a same time. Because they were eaten at a same time, it raise a Occurrence of Cold and Heat syndromes and a Qi disorder.

• 약학회지
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• 제8권2호
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• pp.35-36
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• 1964

One of projects of this institute is phytochemical survey of the herb drugs in Korea for further study. A hundred and fifteen species of plants which are used currently as herb drugs in Korea were screened on the presence of alkaloids, phenolic compounds, flavonoids, chalcones, lactones, glucosides, carbohydrates, terpenoids, steroids, proteins, polypeptides, saponins, and organic acids, and the most reliable presence of alkaloids was detected by paper chromatography. In this paper, presence of alkaloids is also tabulated after screening other 50 species.

• 동의신경정신과학회지
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• 제8권1호
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• pp.111-125
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• 1997

This study was done in order to investigate Oriental Medicine's meaning on stress, the stress is due to animal experiments.Methods:This research was done by animal experiments's results based on 41 animal experiment treatises carried out by 24 prescriptions about stress control. Each experiments were compared with same conditions, minimizing the experiments differences. The results were analyzed by p-value and Increas e·Decrease percentage of experiments result's numerical value. Results:1. Inquire into frequency in use of each stress stimulus and measuring items, the restriction stimulus stress and measuring the content of catecholamines are numerous.2. Significance of stress stimuluses based on experments's results is good by restriction stimulus.3. Oriental Medicine's meaning for stress is pathological phenomenon of Seven Emotion(七情). Stagnant the Energy(氣鬱), the Fire(火), Dam(痰), Lack of the general Blood thing(血虛), and reaction of an individual body.4. Inguire into the effects of frequency in use of experiments's Herb drugs, Herb Drugs of Tonifing the general Blood thing depend on stabilized Mind(補血安神), Circulated the Energy and Digest(理氣消導), Tonifing the general Blood thing(補血), Clearing the Mind(淸心), Removing the Dam(祛痰) are numerous.5. From a Sasang Medical point of view, experimental use of Herb Drugs are Soeum-in(少陰人) Herb Drugs are numerous.According to above results, it is considered that Herb Drugs of Tonifing the general Blood thing depend on stabilized Mind(補血安神), Circulated the Energy and Digest(理氣消導), Tonifing the general Blood thing(補血), Clearing the Mind(淸心), Removing the Dam(祛淡), and Soeum-in(少陰人) Herb Drugs are used to prevent stress and related diseases.

• 대한한방내과학회지
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• 제21권1호
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• pp.1-6
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• 2000

Objectives : Herniated lumbar intervertebral disc (HIVD) is one of the cause of low back pain and radiculopathy. To evaluate the efficiency of simultaneous administration of herb medicine and non-steroid-anti-inflamatory drugs (NSAIDs), we investigated 48 HIVD patients confirmed by CT or MRI and treated with acupuncture, bed rest, herb medicine, physical therapy and NSAIDs. Methods : The patients were divided into four groups as follows : The A group were 11 cases treated with only herb medicine A. The A+W group were 14 cases treated with herb medicine A and NSAIDs. The B group were 11 cases treated with herb medicine B. The B+W group were 12 cases treated with herb medicine Band NSAIDs. We evaluated the pain degree by visual analog scale (VAS). Results : The mean VAS was reduced to $4.89{\pm}2.62$ after 2 weeks therapy and pain decrease was the most prominent in the group having within a week duration ($3.25{\pm}2.49$). Pain scale was decreased to $4.57{\pm}2.95$ in A+W group, $4.91{\pm}1.97$ in A group, $4.72{\pm}2.68$ in B group, and $5.41{\pm}2.67$ in B+W group after 2 weeks therapy. Conclusions : These results indicate that oriental medical theraphy is useful enough to treat the HIVD patients and herb medicine decrease the pain of the HIVD effectively. Therefore, the more research about herb medicine for pain killing drugs should be done.

• 한국식품위생안전성학회지
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• 제8권3호
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• pp.141-145
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• 1993

수종의 병원성 미생물에 대한 39여종의 생약 열수추출액의 항균성을 조사한 결과 다음과 같은 결과를 얻었다. 황백 Phellodendron amurense 및 황령 Coptis chinensis 는 Staphylococcus aureus균의 생육을 억제시켰으며 복분자 Rubus creanus는 Staphylococcus aureus 및 Pseudomonas aeruginosa에 항균력을 나타내었다. 진피 Citrus unshiu는 E.coli에 대해서 산수유 Cornus officinalis는 Candida albicans의 생육을 억제시켰고 우슬 Achyranthes japonica 및 감초 Clycyrrhiza uralsis는 Aspergillus niger에 뚜렷한 항균효과를 나타내었다. 또한 감초는 Staphylococcus Aureus, E. coli, Pseudomonas aeruginosa , Aspergillus niger 모두에 항균력을 나타내었다.

• 셀메드
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• 제4권3호
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• pp.17.1-17.8
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• 2014

Herbal remedies are commonly used by patients worldwide. Because these herbal preparations share the same metabolic and transport proteins with prescribed medicines, the potential for a drug-herb interaction is substantial and is an issue of significant concern. This review paper summarizes drug-herb interactions involving inhibition or induction of cytochrome P450 enzymes, drug transporters as well as modulation of drug pharmacodynamics. An increasing number of in vitro and animal studies, case reports and clinical trials evaluating such interactions have been reported, and implications of these studies are discussed in this review. The most commonly implicated drugs in the interaction include anticoagulants, antiplatelets, immunosuppressants, anti-neoplastics, protease inhibitors, and some antidepressants. Pharmacokinetic and/or pharmacodynamic interactions of five commonly used herbal remedies (danshen, garlic, Ginkgo biloba, ginseng, and St John's wort) with these drugs are presented, with focus of discussion being the potentials for interaction, their mechanisms and clinical implications. There is a necessity for adequate pharmacovigilance to be carried out in minimizing unanticipated but often preventable drug-herb interactions.

• 한국자원식물학회지
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• 제5권2호
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• pp.105-111
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• 1992

It was explained in detail that the present condition of herb culture in Japanese agriculture and the requirement of crude drugs of good and regulqr very hard hit by the market conditionof crude drugs taking ginseng (Panax ginseng C.A.Meyer) and Coptis Rhizome (Coptis japon-ica Makino) as examples. It is not too mach to say that the market is now under the control ofcrude drugs imported from China. The main current of herb culture in Japan will be the con-tract agriculture that the seedlings of good and regular quality are received and are cultivateduntil the enough time, and the farm products are directly handed to the medicinal company fol-lowing the example of zedoary (Curcuma zedoaria Roscoe) .

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.103.1-103.1
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• 2003

This study was carried out to investigate sulfur dioxide in herb drugs.(Puerariae Radix, Lycii Fructus, Platycodi Radix, Dioscoreae Rhizoma, Mori Radicis Cortex, Nelumbo Seed, Paeoniae Radix, Remotiflori Radix, Astragali Radix, Polygonatum Rhizome) Experimental subjects included 105 cases of 10 species of herb drugs collected in Kyung-dong market from December in 2001 to February in 2002. Sulfur dioxide was determined by Optimized Monier-Wiliams method. In 65 cases(61.9%) of the 105 cases, we detected $SO_2$ over 10mg/kg. (omitted)

• 대한한방내과학회지
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• 제29권4호
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• pp.887-903
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• 2008

Objectives : We present some opinions to reduce the risk of herb-drug interactions through scanning "About Herbs" of the Memorial Sloan Kettering Cancer Center Website. Methods : We searched the Memorial Sloan Kettering Cancer Center Website of About Herbs and investigated herb-drug interactions. Results : There are 237 herbs and 196 drugs on About Herbs. 81.1% of herbs have fewer than 2 interactions listed.: 86.3% of drugs fewer than 3 interactions. Especially, 13 herbs were reported to have interactions with inclusive chemoagents on About Herbs. Only L-theanine has positive interaction with inclusive chemoagents. The others have negative interactions with inclusive chemoagents. 12 single chemoagents were reported to have interactions with some herbs. Especially tamoxifen-black cohosh, methotrexate-glutamin and aldesleukin-Huang Chi have positive interactions to increase the effects of the chemoagent. Conclusions : We should urgently create a risk management system of herb-drug interactions and take note of the risk of herb-drug interactions. We should build up systemic, evidence-based informations on popular herbs used by Korean cancer patients and herb-drug interactions in oncology like About Herbs.