• Journal of Acupuncture Research
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• v.40 no.1
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• pp.1-15
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• 2023

Between May 2014 and April 2022, a total of 926 articles were retrieved from the international database, and a total of 233 articles were retrieved from the Korean database. From there, 14 studies were selected, and evaluated by the published year, terminology of the acupotomy, sample size, disease type, retention time, treatment sites, insertion depth and size of the acupotomy, treatment frequency, and duration, type of acupotomy manipulation method, evaluation index, therapeutic effects, adverse effects, and assessment of the risk of bias in randomized controlled trials. This study examined the need for additional acupotomy studies to secure an objective basis for the application of clinical treatment. Furthermore, the detailed description of the study methods and results and unified terminology can provide evidence for the efficacy of acupotomy.

• Journal of Acupuncture Research
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• v.40 no.3
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• pp.201-213
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• 2023

This study reviewed clinical papers reported on hemifacial spasm (HFS). Six online databases were searched for clinical papers published between January 2000 and December 2022. This study reviewed 14 studies, including 13 case reports and 1 combination of case reports and randomized controlled trials (RCTs). The most frequently used acupoints were ST7 and TE17, and the stomach meridian was the most frequently selected. Herbal medicine, pharmacopuncture, thread embedding acupuncture, cupping, moxibustion, and physical therapy were combined with acupuncture. The most frequently used evaluation method is Scott's scale. Out of 95 cases, 82 reported improved HFS symptoms after treatment. Our findings indicated the effectiveness of Korean Medicine treatment in treating HFS. However, evidence of efficacy and safety remains insufficient. Large-scale and well-designed investigations will be required in the future to corroborate these results. We believe that this paper will serve as the foundation for future RCTs.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.05a
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• pp.413-415
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• 2021

Piano is one of the most beloved instruments in the world and is used a lot for children to learn music because it is simple to play. As a result, various products for children, such as toy pianos, were released. However, there is a lack of piano skills for music education, such as how to play the piano or read the score. To solve this problem, in this paper, we propose a game-style educational piano using Arduino. It is expected to capture fun and education at a low price by scoring points by displaying the score on the LCD screen and pressing the keyboard according to the timing of playing the note.

• Proceedings of the Korean Society of Computer Information Conference
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• 2023.01a
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• pp.415-416
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• 2023

본 연구는 코로나로 인하여 외국인들도 한국을 방문율이 낮아지고 성형 수술 가격 및 부작용 등 부정적인 측면으로 인해 사람들이 성형 수술을 하기에 꺼리는 상황 속에서 성형 수술을 하는 사람들의 조건, 성형 수술을 하는 이유, 성형 수술 부위, 성형 수술의 부위별 가격을 분석하여 결과를 제시하였다. 성형 수술에 대해 부정적인 견해를 보이는 사람들에게 성형 수술에 대한 견해를 긍정적으로 바꾸고자 한다. 이외에도 한국의 성형 수술이 발전하기 위해서는 한국 외에도 외국의 다양한 수술과 연계 방안 탐색 필요성을 느꼈고 데이터셋, 사이트 외에도 유튜브를 통한 영상 정보를 지속적으로 업그레이드 시켜서 성형 수술의 접근성과 우수성을 알릴 수 있는 기회를 모색한다면 국내뿐만 아니라 세계적으로 한국의 성형 수술에 대해 많은 관심을 보일 것이라고 사료된다.

• Annual Conference on Human and Language Technology
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• 2023.10a
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• pp.711-715
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• 2023

본 연구는 대부분의 언어 모델이 사용하고 있는 서브워드 토큰화 과정을 거치지 않고, 바이트 단위의 인코딩을 그대로 다룰 수 있는 토큰-프리 사전학습 언어모델에 대한 것이다. 토큰-프리 언어모델은 명시적인 미등록어 토큰이 존재하지 않고, 전 처리 과정이 단순하며 다양한 언어 및 표현 체계에 대응할 수 있는 장점이 있다. 하지만 관련 연구가 미흡, 서브워드 모델에 대비해 학습이 어렵고 낮은 성능이 보고되어 왔다. 본 연구에서는 한국어를 중심으로 토큰-프리 언어 이해-생성 모델을 사전 학습 후, 서브워드 기반 모델과 비교하여 가능성을 살펴본다. 또한, 토큰 프리 언어모델에서 지적되는 과도한 연산량을 감소시킬 수 있는 그래디언트 기반 서브워드 토크나이저를 적용, 처리 속도를 학습 2.7배, 추론 1.46배 개선하였다.

• Molecular Medicine Reports
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• v.20 no.4
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• pp.3301-3307
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• 2019

c-Myc is a characteristic oncogene with dual functions in cell proliferation and apoptosis. Since the overexpression of the c-Myc proto-oncogene is a common event in the development and growth of various human types of cancer, the present study investigated whether oncogenic c-Myc can alter natural killer (NK) cell-mediated immunity through the expression of associated genes, using PCR, western blotting and flow cytometry assays. Furthermore, whether c-Myc could influence the expression levels of natural killer group 2 member D (NKG2D) ligands, which are well known NK activation molecules, as well as NK cell-mediated immunity, was investigated. c-Myc was inhibited by 10058-F4 treatment and small interfering RNA transfection. Upregulation of c-Myc was achieved by transfection with a pCMV6-myc vector. The inhibition of c-Myc increased MHC class I polyeptide-related sequence B and UL16 binding protein 1 expressions among NKG2D ligands, and the overexpression of c-Myc suppressed the expression of all NKG2D ligands, except MHC class I polyeptide-related sequence A. Furthermore, the alteration of c-Myc activity altered the susceptibility of K562 cells to NK cells. These results suggested that the overexpression of c-Myc may contribute to the immune escape of cancer cells and cell proliferation. Combined treatment with NK-based cancer immunotherapy and inhibition of c-Myc may achieve improved therapeutic results.

• Journal of Korean Medicine for Obesity Research
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• v.7 no.1
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• pp.87-96
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• 2007

Objectives : This study was performed to evaluate the effect of oriental medical treatment on aged female obese patient. Methods : We experienced an aged female obese patient. We applied herbal medication(Choweseuncheng-tang), electrolipolysis, auricular acupuncture to her from 26th, March. 2007 to 25th, May. 2007. And we examined the changes of her weight, body composition, body size, skin resistance variability, visual analogue scale of knee pain. Results : 1. Her weight decreased from 73.5kg to 71.1kg and body mass index(BMI) decreased from $29.46kg/m^2$ to $28.11kg/m^2$. 2. Body fat mass(BFM) decreased from 25.7kg to 21.6kg but body muscle mass(BMM) increased from 45.1kg to 46.7kg. 3. Waist-hip ratio(WHR) decreased from 0.96 to 0.92. 4. Basal metabolic rate(BMR) increased from 1,273kcal to 1,314kcal. 5. The circumference of upper extremity decreased 1.03cm and lower extremity decreased 1.30cm but the circumference of the muscle of upper extremity increased 0.41cm and lower extremity increased 0.63cm. 6. The circumference of chest and hip are decreased. In addition to the circumference and fat of abdomen are decreased. 7. The visual analogue scale of knee pain is improved. Conclusions : According to above results, oriental medical treatment could be used safety to aged obese patients without loss of fat free mass. The study is more required to aged obese patient from now on.

• Journal of Korean Neurosurgical Society
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• v.44 no.5
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• pp.303-307
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• 2008

Objective: The authors reviewed clinical and radiological outcomes in patients with three column injury of the cervical spine who had undergone posterior cervical fixation using Nitinol shape memory alloy loop in the anterior-posterior combined approach. Materials: Nine patients were surgically treated with anterior cervical fusion using an iliac bone graft and dynamic plate-screw system, and the posterior cervical fixation using Nitinol shape memory loop ($Davydov^{TM}$) at the same time. A retrospective review was performed. Clinical outcomes were assessed using the Frankel grading method. We reviewed the radiological parameters such as bony fusion rate, height of iliac bone graft strut, graft subsidence, cervical lordotic angle, and instrument related complication. Results: Single-level fusion was performed in five patients, and two-level fusion in four. Solid bone fusion was presented in all cases after surgery. The mean height of graft strut was significantly decreased from $20.46{\pm}9.97mm$ at immediate postoperative state to $18.87{\pm}8.60mm$ at the final follow-up period (p<0.05). The mean cervical lordotic angle decreased from $13.83{\pm}11.84^{\circ}$ to $11.37{\pm}6.03^{\circ}$ at the immediate postoperative state but then, increased to $24.39{\pm}9.83^{\circ}$ at the final follow-up period (p<0.05). There were no instrument related complications. Conclusion: We suggest that the posterior cervical fixation using Nitinol shape memory alloy loop may be a simple and useful method, and be one of treatment options in anterior-posterior combined approach for the patients with the three column injury of the cervical spine.

• Journal of the Korean Magnetics Society
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• v.18 no.5
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• pp.185-189
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• 2008

We observe the change of coercivity and exchange bias, depending on inserting material and thickness in a [Pd(0.6 nm)/$Co(0.2)]_5$/ FeMn(10) multilayer structure with perpendicular anisotropy. When 0.78 and 1.28 nm thick NiFe substitutes for Co in a $[Pd(0.6 nm)Co(0.2)]_4$/Pd(0.6)/NiFe(t)/FeMn(10) structure, we obtain the exchange bias of 360 Oe. In addition, when $Co_8Fe_2$ and $Co_9Fe_1$ are inserted for Co/FeMn interface, we obtain the exchange bias of 380 nm for a 0.68 nm thick $Co_8Fe_2$ and 580 Oe for a 0.52 nm thick $Co_9Fe_1$.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.5
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• pp.470-478
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• 2007

The purpose of this study was to investigate the clinical, biomechanical, and histologic changes in new distraction osteogenesis(DO) technique combined with a compression stimulation in accordance to different compression-distraction force ratio. 23 adult male rabbits underwent open-osteotomy at the mandibular body area and a external distraction device was applied. In the control group of 8 rabbits, only a 8 mm of distraction was performed by conventional DO technique. In an experimental group of 15 rabbits, a distraction followed by a compression force was performed according to the ratio of compression-distraction suggested by authors. The rate of experimental group I was set up as a 2 mm compression versus 10 mm distraction and the rate of experimental group II was set up as a 3 mm compression versus 11 mm distraction. All the rabbits were sacrificed for a gross finding, biomechanical, histomorphometric and histologic findings at the time of 55 days from the operation day. The results were as follows: 1. On the gross findings, because all rabbits had a sufficient healing time, every distracted new bone had good bone quality and we could not find any difference among all three groups. 2. In the histologic findings, rapid bone maturation(wide lamellar bone formation in the cancellous and cortical bone areas) was observed in two experimental groups compared to the control group. 3. On the bone density tests, the experimental group II showed higher bone density than the other experimental group and control group(control group-$0,2906g/cm^2$, experimental group I-$0.2961g/cm^2$, experimental group II-$0.3328g/cm^2$). 4. On the biomechanical tests, the experimental group II had significantly higher bone microhardness than the other experimental group and control group(control group-252.7 MPa, experimental group I-263.5 MPa, experimental group II-426.0 MPa). 5. On the microhardness tests, when we compared the hardness ratio of distracted bone versus normal bone, we could find experimental group II had significantly higher hardness ratio than the other experimental group and control group(control group-0.47, experimental group I-0.575, experimental group II-0.80). From this study, we could deduce that the modified distraction osteogenesis method with a compression stimulation might improve the quality of bone regeneration and shorten the consolidation period in comparison with conventional distraction osteogenesis techniques.