• 제목/요약/키워드: Hemisteptia Iyrata Bunge

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Cytotoxic Effects of Sesquiterpene Lactones from the Flowers of Hemisteptia Iyrata B.

  • Ha, Tae-Joung;Jang, Dae-Sik;Lee, Jong-Rok;Lee, Kyung-Dong;Lee, Jun;Hwang, Seon-Woo;Jung, Hwa-Jin;Nam, Sang-Hae;Park, Ki-Hun;Yang, Min-Suk
    • Archives of Pharmacal Research
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    • 제26권11호
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    • pp.925-928
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    • 2003
  • Four guaia-12,6-olide type sesquiterpene lactones, aguerin B (1), 8$\alpha$-acetoxyzaluzanin C (2), cynaropicrin (3), and deacylcynaropicrin (4), were isolated from the flowers of Hemisteptia Iyrata Bunge. It is the first report on the isolation of compounds 1-4 from Hemisteptia species. All the isolates (1-4) were examined for their cytotoxic activity against SK-OV-3, LOX-IMVI, A549, MCF-7, PC-3, and HCT-15 human cancer cell lines.