• BMB Reports
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• v.47 no.2
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• pp.69-79
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• 2014

$Ca^{2+}$ release from intracellular stores and influx from extracellular reservoir regulate a wide range of physiological functions including muscle contraction and rhythmic heartbeat. One of the most ubiquitous pathways involved in controlled $Ca^{2+}$ influx into cells is store-operated $Ca^{2+}$ entry (SOCE), which is activated by the reduction of $Ca^{2+}$ concentration in the lumen of endoplasmic or sarcoplasmic reticulum (ER/SR). Although SOCE is pronounced in non-excitable cells, accumulating evidences highlight its presence and important roles in skeletal muscle and heart. Recent discovery of STIM proteins as ER/SR $Ca^{2+}$ sensors and Orai proteins as $Ca^{2+}$ channel pore forming unit expedited the mechanistic understanding of this pathway. This review focuses on current advances of SOCE components, regulation and physiologic and pathophysiologic roles in muscles. The specific property and the dysfunction of this pathway in muscle diseases, and new directions for future research in this rapidly growing field are discussed.

• Journal of Veterinary Clinics
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• v.21 no.1
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• pp.29-34
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• 2004

Serial ultrasonographic examinations were daily performed on 12 Shih-tzu bitches from 15 days after ovulation until parturition to determine the time of first detection and ultrasonographic appearance of the fetal and extra-fetal structures and to determine the size of gestational structures. Gestational age was timed from the day of ovulation (day 0), which was estimated to occur when plasma progesterone concentration was first increased above 4.0 ng/ml. The gestational length in 12 Shih-tzu bitches was 62.1 (range:60-64) days. The initial detection of the fetal and extra-fetal structures were: gestational sac at days 19.2 (16-21); zonary placenta in the uterine wall at days 25.9 (24-28); yolk sac membrane at days 24.1 (22-26); amniotic membrane at days 26.6 (24-28); embryo initial detection at days 22.3 (21-24); heartbeat at days 23.8 (23-25); limb buds at days 29.3 (27-31); fetal movement at days 32.3 (31-34); stomach at days 32.6 (29-34); urinary bladder at days 33.1 (29-35); skeleton at days 35.9 (34-38) and kidney at days 45.8 (45-48).

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.36 no.4
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• pp.309-313
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• 2000

A experiment was carried out to measure the auditory threshold of dusky spinefoot Siganus fuscescens(Houttuyn) in the coast of Cheju Island by heartbeat conditioning technique using pure tones coupled with a delayed electric shock in order to investigate the hearing ability to audible sound. The audible range of dusky spinefoot extended from 80Hz to 800Mhz with a peak sensitivity at 200Hz. The mean auditory threshold levels of dusky spinefuot were 102dB, 96dB, 92dB, 95dB, 105dB and 121dB respectively in the range of measurement frequencies, As the frequency became higher than 300Hz, the auditory threshold increased rapidly.

• Fashion & Textile Research Journal
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• v.22 no.2
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• pp.209-221
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• 2020

Recently, following the commercialization and market entry of smart clothes with diverse functions, smart clothes have been changing from technology-centered products to user-centered products. However, the analysis of consumer demand centered on actual commercialized products is lacking. Therefore, this study classified commercialized smart clothes by function and analyzed the demand and requirements of smart clothes according to sports/outdoor clothes consumption behaviors. As a result, consumers were classified according to their sports/outdoor clothes consumption behaviors into an outdoor leading group with high consumption propensity, an outdoor pursuit group with medium consumption propensity, and an outdoor following group with low consumption propensity. Among the commercialized smart clothes, those with a heartbeat measuring function, those with a heating function, and those with a light-emitting function were presented and demand analysis was conducted. According to the results, the outdoor leading group and the outdoor pursuit group had higher levels of awareness, preference, and purchase intentions than the outdoor following group. In addition, the outdoor leading group showed the highest level of purchase price acceptance while the outdoor following group showed the lowest level of purchase price acceptance. However, this study has a limitation that the acceptance for smart clothes were analyzed with consumers who had experience in sports outdoor clothes consumption. Therefore, in future, studies will be conducted with a wide range of consumers.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.1
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• pp.243-249
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• 2004

KBPT is the fortified prescription of Bang-pung-tong-sung-san(BPTS) by adding Spatholobi Clulis and Salviae Miltiorrzae Radix. BPTS prescription has been utilized in oriental medicine for the treatments of vascular diseases including hypertension, stroke, and arteriosclerosis. Yet, the overall mechanism underlying its activity at the cellular levels remains unknown. Using spontaneously hypertensive rat (SHR) model, we investigated whether the KBPTS has an effect on the pathophysiological parameters related to hypertension. Pretreatment of SHR with KBPTS was found to lower blood pressure and heartbeat rate. Levels of aldosterone. dopamine, and epinephrine were found to be significantly reduced in the serum of KBPTS-treated SHR. Histological examination of adrenal cortex and superior aorta showed that tissues from KBPTS-treated SHR rats were more intact and cleaner compared to saline-treated control. Levels of superoxide dismutase (SOD) protein in adrenal gland, aorta, myocardial tissue, and kidneys were higher in KBPTS-treated animals than control group. The present data suggest that KBPTS may play a role in normalizing cardiovascular function in SHR by controlling hypertension-related blood factors and superoxide stressors.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.42 no.1
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• pp.214-217
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• 2017

In this paper, we propose a sleep efficiency measurement algorithm based on IR-UWB radar sensor in distance. Among the vital signs which can be measured by the IR-UWB radar sensor such as breathing rate, heartbeat rate, and movement, we analyzed correlation between the movement and the sleep efficiency, and based on the result, we propose a sleep efficiency measurement algorithm. In order to verify the performance of the proposed algorithm, we applied the algorithm to three polysomnography patients in hospitals and obtained the performance of an average absolute error within 3.9%.

• Journal of the Korea Society of Computer and Information
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• v.17 no.4
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• pp.75-82
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• 2012

The Photoplethysmogram is a similar periodic signal that synchronized to a heartbeat. In this paper, we propose a periodic moving average filter that use similarity of Photoplethysmogram. This filtering method has the average value of each samples through separating the cycle of PPG signal. If there are some motion artifacts in continuous PPG signal, disjoin the signal based on cycle. And then, we made these signals to have same cycle by coordinating the number of sample. After arrange these cycles in 2 dimension, we put the average value of each samples from starting till now. So, we can eliminate the motion artifacts without damaged PPG signal.

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.279-286
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• 1997

Serial ultrasonographic examinations were daily performed on 11 bitches (5 Maltese and 3 Yorkshire terrier) from day 15 until parturition to determine the time of Sift detection and ultrasonographic appearance of the fetal and extra-fetal structures. Gestational age was timed from the day of ovulation (day 0), which was estimated to occur when p18sma progesterone concentration was first increased above 4.0 ng/ml. The gestational length in 8 bitches was 61.5 (range: 60-64) days. The initial detection time of fetal and extra-fetal structures were: gestational sac at days 20.5 (18-23); zonary placenta in the uterine wall at days 25.4 (24-30); yolk sac membrane at days 25,5 (23-37); amniotic mombrane at days 28.7 (25-32); embryo initial detection at days 23.3 (20-26); fetal heartbeat at days 23.9 (21-27); fetal movement at days 31.3 (26-34); limb buds at days 32.1 (29-35); rotomarh at days 35.3 (32-40); urinary bladder at days 35.6 (33-39); skeleton at days 37.8 (37- 40) and kidney at days 45.3 (41-49), respectively.

• Journal of Korean Clinical Nursing Research
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• v.23 no.1
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• pp.54-63
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• 2017

Purpose: The purpose of this study was to compare the working status and Standard Shiftwork Index (SSI) between night shift-fixed nurses and rotating shift nurses. Methods: Participants were 367 nurses working as registered nurses at 7 different medical institutions. The data were collected from August 8, 2016 to September 30, 2016. Results: Night shift fixed nurses were more satisfied with work schedule than rotating shift nurses. Rotating shift nurses reported higher SSI scores, such as chronic fatigue, musculoskeletal problems, than night shift fixed nurses. In SSI's sub-items, rotating shift nurses reported higher scores, such as the amount of sleep, feeling well after sleep, heartburn or stomach-ache and heartbeat irregularities, than night shift fixed nurses. Conclusion: The results indicated that night shift fixed system might be an effective method to improve nurses' work satisfaction. It is necessary to figure out any suitable night shift fixed system based on the characteristics of each nursing organization. The SSI might be an useful tool to measure the nurses' satisfaction in reference to their work shift.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.503-504
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• 2017

Recently, economic growth in the world has increased interest in healthy life, and the smart health care industry is growing. In the field of smart healthcare, wearable-type biometric information measurement technology has been highlighted due to the importance of IoT technology. The purpose of this study is to develop a wearable heart - rate monitoring system that can be applied to wearable health care and glove - type monitoring that enables convenient monitoring of heart rate during activity. For this purpose, a glove - type wearable health care system was developed and its performance was evaluated. Experimental results showed that the heartbeat monitoring was possible even in the presence of actual daily activities.