• Title/Summary/Keyword: Heart rates

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Clinical Features and Incidence of Skin Cancer and Precancerous Lesions after Solid Organ Transplantation: A 22-year Single-center Experience in Korea (고형 장기 이식 후 발생하는 피부암과 피부암 전구증으로 최근 22년간 단일 기관을 방문한 환자들에 대한 임상 양상과 인구통계학적 고찰(1995~2017))

  • Park, Chan Seong;Park, Ji-Hye;Lee, Jong Hee;Lee, Dong-Youn;Lee, Joo-Heung;Yang, Jun-Mo
    • Korean journal of dermatology
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    • v.56 no.10
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    • pp.603-608
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    • 2018
  • Background: It is well known that skin cancer and precancerous disease develop more frequently in patients undergoing solid organ transplantation than normal populations in the normal population in Western countries. However, to date, the clinical and demographic features of skin cancer and precancerous disease after solid organ transplantation are not established in Asian countries. We evaluated the clinical and demographic features of primary skin cancer and precancerous lesions after solid organ transplantation and compared these with the trends observed in Western countries. Methods: We retrospectively reviewed the medical records of patients who underwent kidney, liver, heart, and lung transplantation between January 1995 and April 2017 and who developed skin cancer or precancerous lesions after transplantation. The various lesions observed were squamous and basal cell carcinoma, malignant melanoma, Kaposi sarcoma, Bowen's disease, and actinic keratosis. Results: We identified 4604 patients who received organ transplant. The mean age of patients was 44.8 years (male, 64.6%; female, 35.4%), and the sum of the person-year of observation time was 31,024 person-years. The incidence rate per 100,000 person-years was 29.01 for squamous cell carcinoma, 19.34 for basal cell carcinoma, 6.45 for malignant melanoma 3.22 for Kaposi sarcoma, and 74.17 for Bowen's disease and actinic keratosis. The incidence rate per 100,000 person-years was the highest in patients undergoing heart transplantation (610.50), followed by those who underwent kidney transplantation (136.54) and liver transplantation (90.15). Koreans showed lower incidence rates than those observed in Westerners. Conclusion: The incidence of primary skin cancer and precancerous lesions after solid organ transplantation in Koreans was lower than that in Westerners. Squamous cell carcinoma was the most common skin cancer in patients undergoing solid organ transplantation and the incidence rate of skin cancer and precancerous lesions was the highest in patients undergoing heart transplantation.

Pediatric Radiation Examination by Development of Bismuth Shield Research on Radiation Exposure (비스무스 차폐체 개발을 통한 소아 방사선검사의 피폭에 관한 연구)

  • Hoon Kim;Yong-Keun Kim;Joon-Nyeon Kim;Seung-Hyun Wi;Eun-Kyung Park;Myung-Jun Chae;Bu-Gil Baek;Eun-Hye Kim;Cheong-Hwan Lim
    • Journal of radiological science and technology
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    • v.47 no.3
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    • pp.205-211
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    • 2024
  • Currently, with the development of technologies, X-ray examinations for medical examinations at hospital is increasing. This study was conducted to help reduce radiation exposure by measuring the exposure dose received by pediatric patients and the spatial dose of the X-ray room. Dosimeters were installed in the eyeball, thyroid gland, breast, gonads and 4 directions at a distance of 30 cm, 40 cm, 50 cm from the phantom. The dose was measured ten times each, before, and after the application of the bismuth shield under the examination conditions of the head, chest, and abdomen of pediatric patients. Under the condition of head examination, when a shielding was applied, the dose reduction rate was 68.58% for the eyeball, 72.88% for the thyroid, 84.2% for the breast, and 72.36% for the gonad. The chest examination showed reductions of 19.56% eyeball, 56.98% thyroid, 1.21% breast, and 0.68% gonad. The abdominal examination showed reduction rates of 2.6% eyeball, 10.67% thyroid, 19.85% breast, and 82.02% gonad. Spatial dose decreased by 62.25% at 30 cm, 61.16% at 40 cm, and 68.68% at 50 cm. When the bismuth shield was applied, there was a decrease in dose across all examinations, as well as a reduction in spatial dose. Continued research on the use of bismuth shields will help radiological technologists achieve their goal of dose reduction.

Effect of the Auriculoelectrostimulator on Blood Pressure In Hypertensive Rat Models (고혈압모델에서 귀혈위자극기의 혈압강하 효과)

  • Kim Hee-Young;Kim Sung-Ok;Hwang Hye-Jeong;Hahm Dae-Hyun;Lee Kwon-Soon;Kim Soon-Taek;Shim Insop;Lee Hye-Jung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.3
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    • pp.724-728
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    • 2004
  • Several studies have shown that a low frequency stimulation can depress blood pressure in hypertension. We had developed a new auriculoelectrostimulator as an electronic blood pressure regulator for simple and easy stimulation. The new auriculoelectrostimulator was employed in hypertensive rat model induced by immobilization stress, diabetic and essential hypertensive rat models. Rats were stimulated by auriculoelectrostimulator at ear acupoint (Ear point for hypertension) bilaterally. Ear stimulation by auriculoelectrostimulator significantly decreased blood pressure in all hypertensive rat models and inhibited the increase of heart rates in stressed and spontaneous hypertensive rats. The results showed that auriculoelectrostimulator had depressive effects on hypertension in rat hypertensive models, suggesting that it is useful in treatment of hypertension.

Emotion Recognition by Hidden Markov Model at Driving Simulation (자동차 운행 시뮬레이션에서 Hidden Markov Model을 이용한 운전자 감성인식)

  • Park H.H.;Song S.H.;Ji Y.K.;Huh K.S.;Cho D.I.;Park J.H.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.1958-1962
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    • 2005
  • A driver's emotion is a very important factor of safe driving. This paper classified a driver's emotion into 3 major emotions, can be occur when driving a car: Surprise, Joy, Tired. And It evaluated the classifier using Hidden Markov Models, which have observation sequence as bio-signals. It used the 2-D emotional plane to classfiy a human's general emotion state. The 2-D emotional plane has 2 axes of pleasure-displeasure and arsual-relaxztion. The used bio-signals are Galvanic Skin Response(GSR) and Heart Rate Variability(HRV), which are easy to acquire and reliable. We classified several moving pictures into 3 major emotions to evaluate our HMM system. As a result of driving simulations for each emotional situations, we can get recognition rates of 67% for surprise, 58% for joy and 52% for tired.

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The Prevalence Rate and the Risk Factors for Liver Disease among Schoolteachers (교사의 간장질환 유병률 및 질환발생의 위험요인에 관한 연구)

  • Park, Hyun-Ju;Kim, Wha-Juong
    • Journal of the Korean Society of School Health
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    • v.14 no.2
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    • pp.269-277
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    • 2001
  • This study examined the health conditions of schoolteachers in terms of the prevalence rate and risk factors for liver disease. A cohort design was conducted for 21,319 teachers who were born from 1953 to 1957. The cohort was constructed for teachers who had no disease history such as liver disease, hypertension, cerebral vascular disease, heart disease, diabetes mellitus and cancer, and had 'normal' results from liver disease examinations in 1998. They were followed up from 1998 to 2000. SAS 6.12 was used for the data analysis. The results were as follows; (1) Prevalence rates of liver disease per 1,000 people in 1998 were 43.0. (2) The 2-year cumulative incidence of liver disease was 433/16,103(26.9/1000 persons). (3) Factors such as sex, age, school type(private or public), drinking, smoking, exercise, BMI, weight gain, fasting-blood sugar levels and total cholesterol levels were statistically significant. The significant risk factors of liver disease be identified from the multiple logistic regression analysis were age, sex(male), drinking, smoking, BMI, weight gain, fasting-blood sugar levels, and total cholesterol levels.

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Maximum exercise in 20 men Common carotid artery blood flow velocity impact (20대 남성에서 최대운동이 뇌로가는 혈관인 총경동맥 혈류 속도에 미치는 영향)

  • Kim, Ji-Won
    • Journal of the Korean Society of Radiology
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    • v.3 no.4
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    • pp.5-12
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    • 2009
  • Arterial blood from the heart chonggyeong passed directly to the cerebral arteries and the blood circulation is important, especially in arteries that prevent blood flow there are several variables. Among the variables the average flow velocity, pulse index, and blood flow resistance and which variables, double maekbakjisuna systolic and diastolic blood flow resistance index at the maximum rate and blood pressure associated with this because they are important variables, The change of variables such as speed noehyeolryu There are observations about the non-invasive ultrasound measurements using Doppler noehyeolryu uses. Up to 20 men in the exercise of noeroganeun hyeolryuin chonggyeong arteries to increase blood flow rates can be found.

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Fluoroscopic Radiation Exposure during Percutaneous Kyphoplasty

  • Choi, Hyun-Chul
    • Journal of Korean Neurosurgical Society
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    • v.49 no.1
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    • pp.37-42
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    • 2011
  • Objective: The author measured levels of fluoroscopic radiation exposure to the surgeon's body based on the different beam directions during kyphoplasty. Methods: This is an observational study. A series of 84 patients (96 vertebral bodies) were treated with kyphoplasty over one year. The patients were divided into four groups based on the horizontal and vertical directions of the X-Ray beams. We measured radiation exposure with the seven dosimetry badges which were worn by the surgeon in each group (total of 28 badges). Twenty-four procedures were measured in each group. Cumulative dose and dose rates were compared between groups. Results: Fluoroscopic radiation is received by the operator in real-time for approximately 50% (half) of the operation time. Thyroid protectors and lead aprons can block radiation almost completely. The largest dose was received in the chest irrespective of beam directions. The lowest level of radiation were received when X-ray tube was away from the surgeon and beneath the bed (dose rate of head, neck, chest, abdomen and knee: 0.2986, 0.2828, 0.9711, 0.8977, 0.8168 mSv, respectively). The radiation differences between each group were approximately 2.7-10 folds. Conclusion: When fluoroscopic guided-KP is performed, the X-Ray tube should be positioned on the opposite side of the operator and below the table, otherwise the received radiation to the surgeon's body would be 2.7-10 times higher than such condition.

The Prolonged Heart Rate Responses to Electrical Stimulation of Vagus Nerve in Dogs (경부미주신경의 전기자극에 의한 지속성 심박반응 및 이의 심전도적 고찰)

  • Shin, Hong-Kee;Kim, Kee-Soon
    • The Korean Journal of Physiology
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    • v.6 no.2
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    • pp.31-37
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    • 1972
  • The right cervical vagus nerve was electrically stimulated for 30 sec, and 30 minutes recording cardiac rate responses and electrocardiogram. The main purposes of the present experiment are to determine effect of stimulation frequency on the maintenance of cardiac rate responses and to determine recovery time of sinus rhythm after asystole period followed by idioventricular rhythm during prolonged electrical stimulation of the vagus, and the optimal stimulation parameters for vagal stimulation were studied as well. The results obtained are summarized as follows: 1. The maximum negative chrontropic responses were obtained with the following ranges of electrical parameters. Intensity: 3V-7V, Frequency: 20/sec-60/sec, and pulse duration: 5 msec-20 msec. 2. Compared with the responses from sympathetic effectors, cardiac rate responses to electrical stimulation of vagus nerve were well maintained with all stimulation frequencies. 3. At all stimulation frequencies except 20/sec, sinus node started to take over primary pacemaker activity when cardiac rates were restored to about 38-40/min. 4. It was indicated that upper limit of idioventricular rhythm does not exceed 38-40/min. 5. With the stimulation parameter set of 20/sec-5 msec-3 V, sinus rhythm did not appear during 30 minutes of stimulation period. Therefore, this electrical parameter set appears to be optimal for elicitation of prolonged and maximum cardiac rate responses by vagal stimulation.

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Anesthetic and Cardiovascular Effects Induced by a Combination of Midazolam and Thiopental in Dogs (개에 있어서 Midazolam과 Thiopental 병용 투여시 마취 및 심순환기계에 미치는 영향)

  • 김희정;임희란;김휘율
    • Journal of Veterinary Clinics
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    • v.16 no.2
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    • pp.352-362
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    • 1999
  • Thiopental sodium is known as ultrashort-acting barbiturates and can be employed advantageously for numerous conditions. But thiopental has the side effects of cardiovascular and respiratory systems which has barbiturates and are depend on the dose of thiopental. The side effects are reduced when the thiopental is preceded by a tranquilizer and sedative. In these drugs, benzodiazepines have the minimal effects of cardiovascular and respiratory systems. In this study, the effects of midazolam preanesthetic administration, followed by thiopental anesthetic induction, on cardiovascular system and thiopental induction requirement were studied in 14 mixed breed dogs. Cardiovascular data were recorded baseline, after premedication of saline 0.45 ml/kg or midazolam 0.1, 0.2, 0.4, 0.8 mg/kg, intubation, and 5, 10, 15, 20, 30 minutes after intubation. Extubation, head-up, sternal recombency, standing, and walking recovery times were recorded. The results were summarized as follows; (1) The 0.1, 0.2, 0.4, and 0.8 mg/kg dosages of midazolam insignificantly decreased thiopental dose requirement necessary to accomplish intubation by 6, 20, 21 and 28%. (2) The 0.1, 0.2, 0.4, and 0.8 mg/kg dosages of midazolam insignificantly reduced the times of extubation, head-up, sternal recumbency, standing, and walking recovery. (3) Midazolam was effective in reducing the frequency and duration of arrhythmia after intubation. (4) Heart rates of preanestheic midazolam administraion groups increased after thiopental injection which insignificantly changed smaller than those of control group. (5) Arterial blood pressures did not vary significantly among groups.

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Molecular survey of Dirofilaria immitis in mosquitoes collected from parks the in the Incheon metropolitan city in Korea (인천지역 공원 채집 모기에서 심장사상충 감염도 조사)

  • Jeong, Cheol;Song, Jae-Sung;Kim-Jeon, Myung-Deok;Kim, Kyoung-Ho;Lee, Jung-Goo;Lee, Sung-Mo
    • Korean Journal of Veterinary Service
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    • v.43 no.1
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    • pp.1-6
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    • 2020
  • Unlike previous studies that reported the infection rates of Dirofilaria immitis in companion dogs, D. immitis genes were tested directly on mosquitoes to see how many mosquitoes actually carry larvae. Mosquito samples were collected from six parks in Incheon from March to August 2018. A total of 18,589 mosquitoes was collected, classified by type and then made 575 sample pools based on 50 mosquitoes. The PCR method was used to detect Dirofilaria immitis genes of sample pools. Dirofilaria immitis genes were detected in 7 of the 575 pools, and these positive mosquito samples were collected in 4 out of the 6 parks. The types of detected mosquitoes were Aedes dorsalis and Ochlerotatus koreanus which have been identified to act as a vector for heart worm propagation in Incheon. Based on these results, it was concluded that D. immitis genes were found in mosquitoes in the neighborhood park.