• Nutrition Research and Practice
• /
• v.11 no.4
• /
• pp.290-299
• /
• 2017

BACKGROUND/OBJECTIVES: Spirulina is a known a functional food related to lipid profiles, immune functions, and antioxidant capacity. Circulating monocyte chemoattractant protein-1 (MCP-1) level is associated with inflammation markers. Single nucleotide polymorphism in the MCP-1 promoter region -2518 have been identified and shown to affect gene transcription. Gene variation may also impact functional food supplementary effects. The current study investigated the interaction of MCP-1 -2518 polymorphism with spirulina supplements on anti-inflammatory capacity in Korean elderly. SUBJECTS/METHODS: After genotyping, healthy elderly subjects (n = 78) were included in a randomized, double blind, and placebo controlled study. Baseline characteristic, body composition, and dietary intake were measured twice (baseline vs. week 16). For 16 weeks, subjects consumed 8 g either spirulina or placebo daily. Plasma MCP-1, interleukin (IL) -2, IL-6, tumor necrosis factor (TNF)-${\alpha}$, complement (C) 3, immunoglobulin (Ig) G, and Ig A concentrations and lymphocyte proliferation rate (LPR) were analyzed as inflammatory markers. RESULTS: In the placebo group with A/A genotype, MCP-1 level was significantly increased, but the spirulina group with A/A genotype was unchanged. IL-2 was significantly increased only in subjects with spirulina supplementation. TNF-${\alpha}$ was significantly reduced in subjects with the G carrier. C3 was significantly increased in the placebo group, particularly when A/A increased more than G, but not when spirulina was ingested. LPR was significantly different only in subjects with A/A genotype; there was a significant increase in phytohemagglutinin and lipopolysaccharide induced LPR in the spirulina group. CONCLUSION: In healthy Korean elderly, spirulina supplementation may influence different inflammatory markers by the MCP-1 genotype. These results may be useful for customized dietary guidelines to improve immune function in Koreans.

• The Journal of Korean Physical Therapy
• /
• v.32 no.4
• /
• pp.193-197
• /
• 2020

Purpose: The purpose of this study was to investigate the immediate effects of calf muscle Kinesio taping on ankle joint reposition sense (JRS) and force sense (FS) in healthy elderly. Methods: Thirteen healthy elderly subjects were participated in this study. The error of ankle JRS and FS was evaluated by 3D motion capture device and digital dynamometer depending on three different taping conditions (Kinesio taping, sham taping, and no taping) respectively. All of subjects were asked to perform a proprioceptive task of ankle JRS and FS. One-way repeated ANOVA test was used to compare the error of JRS and FS depending on three different taping conditions. Results: With Kinesio taping over calf muscle, ankle joint reposition sense error and force sense error significantly decreased, if compared with a sham taping or no taping condition. Conclusion: To apply Kinesio taping over calf muscle could enhance ankle proprioceptive sense in the elderly people.

• Journal of Korean Physical Therapy Science
• /
• v.24 no.1
• /
• pp.49-58
• /
• 2017

Purpose: To determine the effect of Functional movement screen(FMS) of Healthy subjects. Method: 18 subjects were randomly assigned toFunctional movement screen test. To measure functional movement screen(deep squat, hurdle step, in line lunge, shoulder mobility reaching, active straight leg raise, trunk stability push up, rotary stability). Result: FMS scores were deep squat 2.61score, right hurdle step 2.67 score, lift hurdle step 2.83 score, in line lunge 2.83 score, right shoulder mobility 2.67 score, left shoulder mobility 2.61 score, right active straight-leg raise 3.00 score, left active straight-leg raise 3.00 score, trunk stability push up 2.33 score, rotary stability 1.94 score. Conclusion: FMS can improve functional movement in healthy adults.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.21 no.6
• /
• pp.1601-1610
• /
• 2007

The purpose of this study was to determine whether a pulse analyzer was useful 1) to characterize the variables of pulse wave of diabetes mellitus group, compared with those of healthy subjects, and 2) to determine Sasang Constitution in diabetes mellitus group and healthy subjects. 1. The sum of pulse pressure (energy) and the ratio of systolic period area (As%), called pulse pressure-related variables, were higher in diabetes mellitus group than healthy group, while the height of dicrotic wave (h5) and the ratio of height of dicrotic wave to height of percussion wave (h5/h1), correlated with arterial compliance, were lower in diabetes mellitus group than healthy group. 2. Taeumin of diabetes mellitus group showed higher pressure-related variables than that of healthy group. 3. Soumin of diabetes mellitus group had shorter the time to dicrotic wave (t5) than that of healthy group. 4. Soyangin of diabetes mellitus group showed higher heart rates and lower values in pulse wave time-related variables, including time to dicrotic wave(t5), time to incisura (t4), total time minus time to incisura (t-t4), total time (t), width of percussion wave (w), and the ratio of width of percussion wave to total time (w/t), than that of healthy group. 5. Contact pressure (CP), sum of pulse pressure (energy), height of pre-incisura (h2), height of incisura (h4), width of percussion wave (w), time to incisura (t4), time to percussion wave (t1), variance of total time (Vt), variance of height of percussion wave(Vp) and the ratio of height of incisura to height of percussion wave (h4/h1) were used to develop the rules of Sasang Constitution Classification with about seventy five percents accuracy. These suggested that the pulse analyzer was useful to evaluate the risk degree of diabetes mellitus and to determine Sasang Constitution among either diabetes mellitus group or healthy group.

• Korean Journal of Biological Psychiatry
• /
• v.2 no.2
• /
• pp.266-274
• /
• 1995

We invesigated whether the circadian rhythms of plasma MHPG and HVA concentrations exist in 11 healthy young adults, and analyzed the patterns of their circadian rhythms. The results were as follows : 1) The change in the mean plasma MHPG concentrations analyzed by repeated measures ANOVA was not statistically significant. Five subjects showed significant circadian rhythms of plasma MHPG concentrations of each individual, and 4 of those had the acrophases between 17PM and 24PM. 2) The change in the mean plasma HVA concentrations analyzed by repeated measures ANOVA was not statistically significant. Six subjects showed significant circadian rhythms of plasma HVA concentrations of each individual, and 4 of those had the acrophases between 21PM and 6AM. In conclusion, the circadian rhythm pattern of plasma HVA concentrations in our result is consistent with the previous study. It was suggested that plasma MHPG and HVA concentrations should be measured more frequently, and the physical activities of subjects be controlled more strictly for the following study.

• Journal of the Korean Society for Precision Engineering
• /
• v.32 no.10
• /
• pp.885-890
• /
• 2015

Walking on split-belt treadmill has been applied to study walking disabilities, such as osteoarthritis (OA), to show asymmetric walking characteristics. In this study, we compared asymmetric walking in OA patients with healthy subjects under split-belt conditions and examined the reproduction of walking asymmetry in OA. Seven OA patients were instructed to walk at four frequencies, while four healthy subjects walked on a treadmill with tied-belt and split-belt conditions. To compare walking asymmetries, kinetic and kinematic measurements were made using force-plates and motion capture cameras, and subsequently center of mass (CoM) velocity, mechanical work and potential energy were calculated. Horizontal velocity change during split-belt walking of healthy subjects was similar to OA patients. Difference of mechanical work during single support phase occurred due to fall of CoM in fast belt. OA walking asymmetry could be reproduced by reducing differences of belt speeds to prevent rapid fall of CoM.

• The Journal of Korean Physical Therapy
• /
• v.32 no.5
• /
• pp.273-276
• /
• 2020

Purpose: The purpose of this study was to investigate the effects of the resistance conditions on the electromyography (EMG) activity ratio of vastus medialis oblique (VMO) and vastus lateralis (VL) muscle during partial lunge exercise in healthy subjects in order to suggest the basic data of exercise intervention for such as patients with patellofemoral pain syndrome (PFPS). Methods: The participants of this study were healthy twenty two people with no knee pain, limitation of motion and past history of operation at lower extremity. The participants performed three types of lunge 1) no resistance, 2) anterolateral 45° resistance and 3) lateral 90° respectively. The EMG activity of the VMO and VL were recorded by surface EMG and the measured data normalized by the %MVIC value was analyzed by repeated measured ANOVA. Results: The results showed that the VMO/VL EMG activity ratio during lunge with anterolateral 45° resistance was significantly higher than with no resistance and lateral 90° resistance (p<0.05). There was no significant difference in VMO, VL, and VMO/VL muscle activity between male and female subjects (p>0.05). Conclusion: This study suggests that partial lunge exercise with anterolateral 45° resistance can increase the VMO/VL muscle activity in healthy subjects. This result could be used as basic data to develop therapeutic exercise programs such as PFPS patients.

• Journal of Korean Institute of Industrial Engineers
• /
• v.24 no.2
• /
• pp.297-309
• /
• 1998

Numerical parameters have been developed to diagnose L4/L5 disc patients during repetitive flexions and extensions. Electromyography(EMG) has been used to define the muscle excitation and movement cycle in this study. Twenty healthy subjects and twenty L4/L5 disc patients were recruited for the experiment. The subjective pain levels of patients were recorded as $3.7{\pm}1.6$ according to visual analogue scale where 10 was the maximum pain level. Variance ratio of motion cycle was suggested as a new parameter to examine the consistency of the trunk movement. The results indicated that the temporal EMG pattern such as peak time difference between Quadriceps and Hamstrings, the duration of coexcitation between Erector spinae and Rectus abdominis muscle pairs showed a statistically significant difference between healthy subjects and patients. Variance ratio of External oblique and Internal oblique also showed a statistically significant difference. It is expected that those results could be used for diagnosis by building a database for various back pain patients and healthy subjects. This method can eventually help physicians for early diagnosis and prevention of low back disorders.

• Journal of the Korean Society of Physical Medicine
• /
• v.7 no.1
• /
• pp.21-28
• /
• 2012

Purpose : The purpose of this study was to examine the gait parameter and plantar foot pressure of adults with Down syndrome(DS) during walking in order to provide data for developing evidence-based deficit or common rehabilitation strategies. Method : 15 participants with DS(12 men, 3 women; age $26.06{\pm}4.47$) and 15 healthy subjects(12 men, 3 women; age $25.33{\pm}3.43$) were matched age. They walked at self selected speeds on a GAITRite system and RS-scan system, and had the following measurements done: cadence, stride length, step width, foot angle, percent stance, percent double support, and plantar foot pressure in 10 areas of the foot. Results : In comparison of gait parameter(cadence, stride length, step width, foot angle, percent stance, and percent double support) between adults with DS and healthy subjects, there was significant differences(p<.05). Regarding plantar foot pressure during gait with or without DS, there were statisically significant differences in the area of Toes 1-5, Metatasal 1-4, Midfoot, and Heel(Medial and lateral)(p<.05). Conclusion : Our data show that DS walk with a less physiolosical gait pattern and plantar foot pressure than healthy subjects. Based on our results, DS patients need targeted rehabilitation and exercise strategies.

• Journal of the Korean Society of Physical Medicine
• /
• v.4 no.1
• /
• pp.9-14
• /
• 2009

Purpose : The purpose of this study is change of lumbar multifidus muslce recorded simultaneously by ultrasound imaging during upper extremity functional movement in chronic low back pain patients. The subject were consisted of 10 women patients with chronic low back pain and healthy asymptomatic subject 10 women. Methods : 10 women patients with chronic low back pain and healthy asymptomatic subject 10 women is voluntary participated for the research. Subjects were positioned in standing. Multifidus size were measured from L4 vertebral segement. The ultrasound imaging apparatus(Sonoace 6000, Medison, Korea) was epuipped with a 5-MHz convex array transducer. The upper extremity lifting movement used to activate the multifidus was then measured. Results : Results of the analysis showed that at the L4 vertebral leves, healthy asymptomatic subjects had significantly larger multifidus muscle compared with chronic LBP subjects. Conclusion : This study will be used as treatment method of patient with chronic LBP. The multifidus muscle in chronic LBP patients clinical significance. Most of chronic LBP patients have multifidus contraction pattern. Especially multifidus contraction in L4 vertebral segement. So chronic LBP patients necessary multifidus muscle release treatment.