• The Korean Journal of Nuclear Medicine
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• v.22 no.2
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• pp.181-185
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• 1988

Since hepatocyte clearance, leading edge parencymal transit time and biliary excretion can be evaluated separately with hepatobiliary scan using $^{99m}Tc-DISIDA$, hepatobiliary scan may be useful in differentiating intrahepatic cholestasis from extrahepatic cholestasis. Excretory liver function was analysed in 13 healthy subjects and 11 patients with clinically suspected hepatocellular disease and 9 patients with extrahepatic biliary obstruction confirmed by surgery, radiological and clinical evidence. Indices of total liver activity (% TLA), liver parechymal uptake (% LPU), heart pool clearance (% HPC) and liver-heart rate (% LHR) were calculated from time activity curve over heart and liver. Compared with healthy subjects, significant reduction (p<0.05) in total liver activity (% TLA) and liver-heart rate (% LHR) was observed in all patients group. But no useful indices was demonstrated in differentiating hepatocellular disease from extrahepatic biliary obstruction.

• Journal of Community Nutrition
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• v.5 no.2
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• pp.112-119
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• 2003

Dietary counseling is undoubtedly important for prevention and treatment of chronic diseases. Several dietary counseling methods have been developed and used in Japan to promote healthier diets. However, in Japan, few studies have established effective counseling methods. We developed a computer-assisted tailored dietary counseling system with self-administered diet history questionnaire (DHQ) to assess nutrient intakes and the feedbacks for counseling. We examined the effectiveness of the system in three studies , two among mildly-hypercholesterolemic and one among healthy subjects. We observed significant changes in intakes of targeted nutrients in all three studies. We also observed favorable changes in the corresponding serum and urinary biomarkers in two studies, i.e., non-significant change in serum cholesterol, serum carotene and vitamin C, and a significant change in 24-hour urinary excretion of sodium. In addition, one of the studies observed a significant modified dietary habit for one-year after the intervention was completed. No unfavorable change was observed for non-targeted nutrients in all three studies. The dietary counseling system with DHQ was concluded to be effective among motivated high-risk and healthy subjects. The system's application to other diseases and populations such as children, adolescents, and elderly, should be examined further. (J Community Nutrition 5(2) : 112-119, 2003)

• Journal of the Korean Society of Industry Convergence
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• v.23 no.3
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• pp.523-529
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• 2020

Foot drop is a common symptom in stroke patients due to central nervous system (CNS) damage, which causes walking disturbances. Functional electrical stimulation (FES) is an effective rehabilitation method for stroke patients with CNS damage. Aim of this study was to determine the effectiveness of 6 weeks FES walking training based lower limb muscle synergy of stroke patients. Lower limb muscle synergies were extracted from electromyography (EMG) using a non-negative matrix factorization algorithm (NMF) method. Cosine similarity and cross correlation were calculated for similarity comparison with healthy subjects. In both stroke patients, the similarity of leg muscle synergy during walking changed to similar to that of healthy subjects due to a decrease in foot drop during. FES walking intervention influenced the similarity of muscle synergies during walking of stroke patients. This intervention has an effective method on foot drop and improving the gait performance of stroke patients.

• Journal of Nutrition and Health
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• v.29 no.8
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• pp.899-907
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• 1996

This study was conducted to examine how Korean women mange energy metabolism during lactation. Eighteen women recruited were healthy, had normal pregnancies and were required to breast-feed their babies exclusively for at least 12wks. During the study period, all subjects were visited and interviewed five times : 3d, 9d, 4wk, 8wk, and 12wk lactation. Body composition variables were analyzed by a bioelectrical impedance method, energy intakes were assessed by using the inventory-weighing method, energy expenditure were determined by recording daily activities, and milk energy output was investigated from the amount of milk production and the gross energy content of milk. The subjects consumed less energy than current recommended allowance all over the study period, but compatible with fairly adequate lactational performance. They responded the additional energy stress of lactation by enhancing metabolic efficiency, increasing energy intakes, reduction physical activities and mobilizing body reserves. Another finding in this study was that the reduction in body fat-free mass may be the one way that women meet the energy demands of lactation like the reduction in body fat mass. The results from this study suggest that current recommended additional energy need during lactation, 2.09MJ/d(500kcal/d), is too high for healthy Korean women. Our data also indicate that the changes of body composition and energy balance at earlier postpartum are extremely different from those at later periods.

• YAKHAK HOEJI
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• v.53 no.5
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• pp.250-258
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• 2009

Male reproductive function seems to have deteriorated considerably in the past 4 to 5 decades. It was observed a significant decline in mean sperm counts from $113{\times}10^6/ml$ in 1940 to $66{\times}10^6/ml$ in 1990; a fall of $0.94{\times}10^6/ml/year$. We reported that Yacon tuber extracts have spermatogenic effects in rat. In the present study, we tested the spermatogenic effect of Yacon tuber extracts in healthy male volunteers. Subjects were assigned randomly to the control group and the Yacon ethanol extracts administered group (each 12 subjects). And, placebo or Yacon tuber extracts (100 ml) were administered two times daily, by oral for 3 months. Sperm numbers, biochemical parameters and hormone levels were recorded before starting administration, then every month. The Yacon tuber extracts administered group showed significant time dependant increases in according to administration period. Especially, the numbers of sperm increased by 54% after 3 months of administration. And, in Yacon tuber extracts administered group, testosterone and estradiol level were significantly higher than placebo group. On the other hands, Yacon tuber extracts didn't show any toxicity in glucose and lipid metabolism and liver and kidney function. The results of the present study suggest that Yacon tuber extract is a possible therapeutic for the treatment of sperm deficiency.

• Journal of Institute of Control, Robotics and Systems
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• v.20 no.9
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• pp.971-976
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• 2014

Haptic device can be a useful rehabilitation tool in balance training. The proposed system is composed of a body-wear smartphone, Phantom Omni(R) device, and its control PC system. Ten young healthy subjects performed balance tasks with different postures during 30 seconds with their eyes closed. An Android program on the smartphone transferred mediolateral (ML) and anteroposterior (AP) tilt angles to the PC system, which can generate haptic command through haptic device. Statistical data analysis was performed using MATLAB(R). COP (Center of Pressure) related indexes were measured to see reduction in body sway. ANOVA showed that haptic device significantly reduced body sway. Intuitive balance guidance could be generated using an economical and small-sized commercial haptic device, making the system efficient.

• Journal of The Korean Society of Integrative Medicine
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• v.1 no.3
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• pp.51-62
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• 2013

PURPOSE : This study of 20 healthy male subjects by applying various scapular stabilization exercise to compared Serratus anterior and lower trapezius is change in ultrasound images. METHOD : Thirty healthy subjects voluntarily participated in this study. Ultrasound imaging was recorded from the increasing the activity of Serratus anterior(SA) and Lower trapezius(LT) muscles using Push-up plus, Wall slide, Scapular plane shoulder elevation with resistance exercise. Thickness changes in the Serratus anterior(SA) and lower trapezius(LT) muscles between the relaxed and contracted states in the each exercises. To identify statistical significance, one-way ANOVA with repeated measures was used with the significance level of .05. RESULT : The results of this study were as follows : 1) There were statistically significant difference in thickness changes in the Serratus anterior(SA) and lower trapezius(LT) muscles between the relaxed and contracted states in the each exercises. 2) The Scapular plane shoulder elevation with resistance is more effective to Strengthening in the scapular stabilization muscles than Push up-plus and Wall slide. CONCLUSION : The Scapular plane shoulder elevation with resistance may be used to effectively that patient with various shoulder pain.

• The Journal of Korean Physical Therapy
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• v.27 no.4
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• pp.270-274
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• 2015

Purpose: The purpose of this study was to examine the electromyographic (EMG) activity of the abdominal muscles and to compare the activity ratios of the bilateral rectus abdominis (RA) to oblique abdominal muscles during shoulder abduction in opposite directions with single leg raising (SLR) performed in the supine position on a foam roller. Methods: Fifteen healthy subjects were recruited to the study. Each subject lay on the foam roller and performed left single leg raising with right or left shoulder $90^{\circ}$ abduction (Abd); performed in a random order. Surface EMG recordings of selected abdominal muscles (i.e., the RA, external oblique abdominis [EO], internal oblique abdominis [IO], and transverse abdominis [TrA]) were normalized to maximum voluntary isometric contraction. EO/RA and IO and TrA/RA ratios were determined with surface EMG. Data were analyzed by Independent t-test. The statistical significance level was p<0.05. Results: The results were as follows: (1) the right RA, left EO, and right IO and TrA muscle activities increased significantly at the left SLR with left Abd compared to the left SLR with right Abd (p<0.05); and (2) the ratio of right EO/RA activity increased significantly at the left SLR with right Abd compared to left Abd (p<0.05). Conclusion: These findings suggest that left SLR with left Abd on a foam roller is an appropriate exercise for activation of specific oblique abdominal muscles.

• Journal of Korean society of Dental Hygiene
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• v.2 no.2
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• pp.201-213
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• 2002

The closely related species Actinobacillus actinomycetemcomitans, Hemophilus aphrophilus and Hemophilus paraphrophilus are common findings in oral microbiota. The aims of this study were to compare the distribution of three species in healthy subjects and periodontitis patients using PCR for 16s rRNA gene. The DNA was extracted from the subgingival plaque and saliva in 122 subjects for restriction enzyme analysis with Hinf I and Hha I. In case of periodontally healthy person, A. actinomycetemcomitans was predominant than H. paraphrophilus in saliva sample, but H. paraphrophilus was predominant than A. actinomycetemcomitans in subgingival plaque sample. On the contrary, in case of periodontitis patients, H. paraphrophilus was predominant than A. actinomycetemcomitans in saliva sample, but A. actinomycetemcomitans was predominant than H. paraphrophilus in subgingival plaque sample. In addition, the fact was confirmed that the distribution of A. actinomycetemcomitns of women periodontitis patients was somewhat higher than men periodontitis patients in saliva and subgingival plaque samples. We convinced that the PCR method for 16s rRNA gene was important for screening and monitoring of periodontal disease.

• Journal of International Academy of Physical Therapy Research
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• v.9 no.1
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• pp.1413-1419
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• 2018

The purpose of this study was to examine the effects of hemispheric damage in body composition of male adults with stroke experiences. The Fourth and Fifth Korea National Health and Nutrition Examination Surveys (KNHANES) with body composition results obtained from the DXA (dual-energy X-ray absorptiometry) assessments were used for this study. Survey data of 18 post-stroke men and 28 healthy controls were obtained. Both the lean and fat masses of the upper and lower limbs were utilized to compare for the compositions between the limbs in post-stroke subjects. In addition, the effect of exercise habit was also observed for the influence of physical activity in body composition. Mixed results in left and right limb compositions were shown between the groups. When the subjects were further divided based on walking days per week, sedentary (walk ${\leq}2d/wk$) post-stroke group showed significantly greater fat mass and less lean mass than the physically active people (walk ${\geq}3d/wk$). In comparison to the healthy sedentary and physically active controls, two post-stroke groups showed greater variations. The results indicate that physical activity maintains or improve the quality of both the upper and lower limb composition in patients with post-stroke men.