• 제목/요약/키워드: Healthy subjects

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특발성 파킨슨병 환자의 하지 완서증 정량화를 위한 발 두드리기 동작의 각속도 분석 (Analysis of Angular Velocity during Toe Tapping for the Quantification of the Lower Limb Bradykinesia in Patients with Idiopathic Parkinson's Disease)

  • 김지원;권유리;엄광문;김형식;이정한;권도영;고성범;박병규;권대규
    • 전기학회논문지
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    • 제59권11호
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    • pp.2114-2118
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    • 2010
  • The purpose of this study was to analyze bradykinesia of toe tapping movement in patients with Parkinson's disease (PD) as compared to those of normal subjects. 39 PD patients (age: $65.5{\pm}11.2$ yrs, H&Y stage:$2.3{\pm}0.5$), 14 eldelry subjects with comparable mean age ($65.0{\pm}3.9$ yrs) and 17 healthy young subjects ($24.1{\pm}2.1$ yrs) participated in this study. Angular velocity during repetitive toe tapping movement was measured in both feet using a gyro sensor system. Suggested quantitative measures of bradykinesia were root-mean-squared (RMS) angular velocity, RMS angle, peak power and total power which were derived from the angular velocity signal. ANOVA showed that all measures were significantly different among three groups (p<0.001). Subsequent post-hoc test revealed that all measures in PD patients were significantly smaller than in healthy elderly and healthy young subjects (p<0.02). All measures were significantly correlated with UPDRS scores(r=-0.689~-0.825). These results suggest that the developed system can be used as quantitative measures of the lower limb bradykinesia in PD patients.

The Effects of Sitting in a Crossed Legs Posture on the Vertebral Angle, Chest Wall Mobility, Pulmonary Function, and Respiratory Muscle Activity: A Preliminary Study

  • Ahn, Hee-Eun;Yoon, Tae-Lim
    • 대한물리의학회지
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    • 제14권3호
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    • pp.13-20
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    • 2019
  • PURPOSE: Sitting with crossed legs may have an effect on maintaining a healthy body posture and proper functioning of the respiratory system. Thus, this study's objective was to identify whether or not sitting with crossed legs affects the vertebral angle, chest wall mobility, the pulmonary function, and the activity of the respiratory muscles. METHODS: Thirty healthy subjects were recruited for this study (16 males and 14 females). The vertebral angle, chest wall mobility, pulmonary function, and the activity of the respiratory muscle were measured while the subjects sat in the correct posture and these factors were again measured with the subjects seated with their legs crossed. Three-dimensional motion analysis was used to determine the trunk and lumbar vertebral angles. Surface electromyography was employed to measure the sternocleidomastoid, the rectus abdominis, and the external and internal oblique abdominis muscles. A tapeline was utilized to evaluate the subjects' chest wall mobility. Spirometry was assessed to determine the forced vital capacity and forced expiratory volume in one second. Paired t-tests were then performed (p<.05). RESULTS: There were significant differences in the trunk and lumbar flexion angles, the chest wall mobility, the activity of the right external oblique muscle, and the left internal oblique abdominis muscle. However, the difference in pulmonary function did not reach statistical significance. CONCLUSION: A crossed leg posture caused slight thoracic extension and lumbar flexion, which may lead to a decrease of the chest wall mobility and also to an imbalance of the abdominal muscles. Therefore, sitting with a crossed leg posture should be avoided. Yet a crossed leg posture did not have any clinical effect on the pulmonary function of healthy people. It may be necessary to study the effects of sitting with crossed legs over an extended period of time for patients suffering with impaired respiratory function.

Effects of Robot-assisted Gait With Body Weight Support on Torque, Work, and Power of Quadriceps and Hamstring Muscles in Healthy Subjects

  • Hwang, Jihun;You, Sung (Joshua) Hyun;Choi, Woochol Joseph;Yi, Chung-hwi
    • 한국전문물리치료학회지
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    • 제28권3호
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    • pp.215-226
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    • 2021
  • Background: Robot-assisted gait training (RAGT) is an effective method for walking rehabilitation. Additionally, the body weight support (BWS) system reduces muscle fatigue while walking. However, no previous studies have investigated the effects of RAGT with BWS on isokinetic strength of quadriceps and hamstring muscles. Objects: The purpose of this study was to investigate the effects of torque, work, and power on the quadriceps and hamstring muscles during RAGT, using the BWS of three conditions in healthy subjects. The three different BWS conditions were BWS 50%, BWS 20%, and full weight bearing (FWB). Methods: Eleven healthy subjects (7 males and 4 females) participated in this study. The Walkbot_S was used to cause fatigue of the quadriceps and hamstring muscles and the Biodex Systems 4 Pro was used to measure the isokinetic torque, work, and power of them. After RAGT trials of each of the three conditions, the subjects performed isokinetic concentric knee flexion and extension, five at an angular velocity of 60°/s and fifteen at an angular velocity of 180°/s. One-way repeated analysis of variance was used to determine significant differences in all the variables. The least significant difference test was used for post-hoc analysis. Results: On both sides, there were significant differences in peak torque (PT) of knee extension and flexion between the three BWS conditions at an angular velocity of 60°/s and 180°/s conditions. A post-hoc comparison revealed that the PT in the BWS 50% was significantly greater than in the BWS 20% and the FWB and the PT in the BWS 20% was significantly greater than in the FWB. Conclusion: The results of this study suggest that the lower BWS during RAGT seems to lower the isokinetic torque, work, and power of the quadriceps and hamstring muscles because of the muscle fatigue increase.

Subgingival microbiome in periodontitis and type 2 diabetes mellitus: an exploratory study using metagenomic sequencing

  • Lu, Xianjun;Liu, Tingjun;Zhou, Jiani;Liu, Jia;Yuan, Zijian;Guo, Lihong
    • Journal of Periodontal and Implant Science
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    • 제52권4호
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    • pp.282-297
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    • 2022
  • Purpose: To explore differences in the subgingival microbiome according to the presence of periodontitis and/or type 2 diabetes mellitus (T2D), a metagenomic sequencing analysis of the subgingival microbiome was performed. Methods: Twelve participants were divided into 4 groups based on their health conditions (periodontitis, T2D, T2D complicated with periodontitis, and generally healthy). Subgingival plaque was collected for metagenomic sequencing, and gingival crevicular fluids were collected to analyze the concentrations of short-chain fatty acids. Results: The shifts in the subgingival flora from the healthy to periodontitis states were less prominent in T2D subjects than in subjects without T2D. The pentose and glucuronate interconversion, fructose and mannose metabolism, and galactose metabolism pathways were enriched in the periodontitis state, while the phosphotransferase system, lipopolysaccharide (LPS) and peptidoglycan biosynthesis, bacterial secretion system, sulfur metabolism, and glycolysis pathways were enriched in the T2D state. Multiple genes whose expression was upregulated from the red and orange complex bacterial genomes were associated with bacterial biofilm formation and pathogenicity. The concentrations of propionic acid and butyric acid were significantly higher in subjects with periodontitis, with or without T2D, than in healthy subjects. Conclusions: T2D patients are more susceptible to the presence of periodontal pathogens and have a higher risk of developing periodontitis. The pentose and glucuronate interconversion, fructose and mannose metabolism, galactose metabolism, and glycolysis pathways may represent the potential microbial functional association between periodontitis and T2D, and butyric acid may play an important role in the interaction between these 2 diseases. The enrichment of the LPS and peptidoglycan biosynthesis, bacterial secretion system, and sulfur metabolism pathways may cause T2D patients to be more susceptible to periodontitis.

건강인을 대상으로 거짓침과 진짜 침을 이용한 침의 효능에 대한 연구: 위전도를 이용한 단일맹검 (Study on the Efficacy of Acupuncture with Real and Sham Needle on Healthy Subjects: Single-Blind Test using Electrogastrogram)

  • 장극영;김건일;유준상;고찬희;이현숙
    • 동의생리병리학회지
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    • 제28권1호
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    • pp.107-112
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    • 2014
  • This study aimed to prove the effects of acupuncture treatment on acupoint Joksamni(ST36) related to gastrointestinal movement. Electrogastrogram (EGG) data were obtained in 11 healthy subjects treated by real or sham needle in single-blinded condition for 40 min, including before, during acupuncture treatment, and after removing needle. According to frequency analysis of EGG, median frequency(MF) was increased by real needle in 4 subjects, MF for another 2 subjects were increased by real and sham needle and no trend shift in MF showed in other 5 subjects. Our result showed that acupuncture treatment on Joksamni has some effects on gastrointestinal movement. In this study we have applied both real acupuncture and sham acupuncture on the same subjects. So its blinding was regarded as good but was effective in about 36%~55%. Two subjects were assumed that they showed placebo effects on both real and sham acupuncture. Therefore it is necessary to perform further study on case-control and a larger number of subjects with functional dyspepsia, in order to confirm our findings.

Comparison of Lumbopelvic Motions During Hip Medial Rotation Depending on Sex Differences and Chronic Lower Back Pain

  • Kim, ChiHwan;Han, JinTae
    • The Journal of Korean Physical Therapy
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    • 제31권2호
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    • pp.117-121
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    • 2019
  • Purpose: Hip rotation testing is important in the evaluation of chronic back pain. The purpose of this study was to investigate hip and lumbopelvic movement during hip medial rotation (HMR) in individuals with chronic lower back pain (CLBP). Methods: This study targeted 112 subjects in total: 28 healthy males and 28 healthy females, and 27 males with CLBP and 29 females with CLBP. Motion-capture device was used to measure the hip medial rotation angle (HMRA), lumbopelvic rotation angle (LPRA), and the rotation angle of the hip when lumbopelvic rotation starts during hip medial rotation. Results: When evaluating the healthy males and females using the hip medial rotation test (HMRT), healthy males showed a smaller HMRA than did healthy females (p<0.05). When evaluating the healthy males and the males with CLBP using the HMRT, males with CLBP showed a smaller HMRA and more lumbopelvic movements than did healthy males (p<0.05) in addition, their lumbopelvic movements occurred earlier during HMR (p<0.05). Finally, when evaluating the males and the females with CLBP using the HMRT, males with CLBP showed a smaller HMRA and more lumbopelvic movements (p<0.05), and their lumbopelvic movements occurred earlier during HMR (p<0.05). Conclusion: The HMRT is an important test for the evaluation of males, and especially males with CLBP, as they often experience an increased LPRA and decreased HMRA, with lumbopelvic movement occurring earlier during HMR when compared to other groups.

사상체질 완실무병(完實無病) 수준에 따른 맥파(脈波) 특성의 후향적 임상 연구 (Retrospective Clinical Study of Pulse Wave Characteristics According to Healthy State Level in Sasang Constitution)

  • 김수현;박준용;김호인;주종천
    • 사상체질의학회지
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    • 제35권4호
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    • pp.1-9
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    • 2023
  • Objectives This study is designed to examine the relationship between healthy state (完實無病) of Sasang constitution and pulse wave (脈波). Methods The subjects were 100 patients who were diagnosed with Sasang constitution and underwent pulse analyzer test. The status of urination, defecation, perspiration, and digestion was classified as good, intermediate, and poor. The power, depth, speed, and roughness of pulse waves (脈波) were analyzed. Results Patients with poor digestion had relatively powerless pulse wave (無力脈). Soeumin patients had a higher rate of poor digestion compared to other constitutions. Soyangin patients had a higher rate of poor perspiration compared to other constitutions. Soyangin with poor defecation had relatively choppy pulse wave (澁脈), and poor perspiraton had relatively slippery (滑脈). Soeumin patients with poor digestion had relatively powerless pulse wave (無力脈). Conclusions The pulse wave of poor healthy state (完實無病) is an expression of a pathological syndromes (病證) caused by lack of or damage to healthy energy (保命之主). It was concluded that the pulse analyzer can be used to evaluate healthy state (完實無病).

건강매점 운영에 따른 청소년의 간식 섭취에 대한 인식 및 간식 구매 행태 (Effect of Healthy School Tuck Shop on Snack Preference and Food Purchasing Behavior in Adolescents)

  • 남경민;강민정;김기랑;김정연;도민희;이상선
    • 한국식품영양학회지
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    • 제27권6호
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    • pp.1147-1155
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    • 2014
  • Adolescence is the most important period of healthy development. The purpose of this study was to evaluate the food recognition, snack preference, and dietary behavior of 1st grade of middle and high school boys and girls. Subjects were 5,554 students from 16 schools with healthy tuck shop and 3,406 students from 9 schools without healthy tuck shop in Seoul, Korea. Students from schools with healthy tuck shop are significantly higher than control group for facility satisfaction and hygiene satisfaction (all p<0.05). For fruit, the preference (p<0.05) and recognition (attitude, p<0.001: intention, p<0.05: eating habit, p<0.001: social-environment, p<0.001: self-efficacy, p<0.001) of students in schools with healthy tuck shop are significantly higher than those in schools without healthy tuck shop. For the habit of checking the manufacturer, students in schools with healthy tuck shop were significantly higher than students in schools without healthy tuck shop (p<0.05). The result suggested that we have to create an environment in which fruits can be purchased easily at a tuck shop and to educate adolescents for the importance of healthy food purchasing behavior. In conclusion, healthy school tuck shop had a positive effect on accessibility to healthy food.

가족정책 전달체계 전담인력의 역량강화를 위한 교육방안 모색을 위한 기초 연구 (A Study on the Education Plan for Empowerment of Healthy Family Specialists in the Family Policy Delivery System)

  • 박정윤;정지영;송혜림;조영희;이현아
    • 가정과삶의질연구
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    • 제33권2호
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    • pp.53-70
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    • 2015
  • The number of Healthy Family Support Centers has dramatically increased and the services for healthy families such as family education, family counsel, family culture and family care have increased during the past ten years since the Framework Act on Healthy Families was enacted. This growth is largely credited to Healthy Family Specialists. At a time when the family policy delivery system is changing, it is most urgent to enhance the capability of Healthy Family Specialists. In this study, we aim to investigate the current capability of Healthy Family Specialists and suggest the education plan for their empowerment. We collected data from 151 Healthy Family Support Centers by mail and e-mail in June 2014. There were total of 1,001 subjects for analysis(781 by mail and 220 by e-mail). We analyzed the capabilities of Healthy Family Specialist by service areas according to work-related characteristics and possession of a license. Our findings revealed that the capabilities of Healthy Family Specialist varied depending on the service year and whether or not having a licence. These results suggest that the education program for empowerment will provide a differentiated content according to the service year and whether or not having a license. This study contributes to a better understanding of Healthy Family Specialists' current capability and provides insights on how to enhance their capability in order to change the family policy delivery system.

건강한 성인에게서 삶의 질과 스트레스, 건강관련 생활습관, 영양소 및 음식 섭취와의 관련성 연구 - 2013 국민건강영양조사를 근거하여 - (The Relationships among Quality of Life and Stress, Health-related Habits and Food Intake in Korean Healthy Adults Based on 2013 Korea National Health and Nutrition Examination Survey)

  • 이수빈;최현진;김미정
    • 대한지역사회영양학회지
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    • 제20권6호
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    • pp.411-422
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    • 2015
  • Objectives: This study investigated the socioeconomic factors that affect quality of life (QL) in healthy adults and to study the relationship between QL and health-related habits and food intake. Methods: Subjects consisted of 1,154 healthy adults without any known disease, aged 19 to 65 years from the 2013 Korean National Health and Nutrition Examination Survey data. We used SPSS statistical program version 20.0 for data analysis. Results: The average age and QL score of the study population were 36.7 years and 0.99 points, respectively. Males had a significantly higher QL score than the females (p < 0.001), and employed subjects and those employed in permanent positions had significantly higher scores as compared respectively with unemployed subjects and those employed in temporary positions (p < 0.001, p < 0.05). The group that responded "almost every day" to the "frequency of binge drinking" and "frequency of disruption of daily life due to drinking" had significantly lower QL scores as compared to other groups (p < 0.05). Further, the scores were significantly higher for individuals who practiced "intense physical activities" and "walking" (p < 0.001). The groups that responded that they were "very stressed" showed significantly lower QL scores in comparison to the other groups (p < 0.05). There were no significant differences in QL scores according to anthropometric or biochemical indices. When subjects were divided into two groups based on average QL scores, the frequency of intake of "barbecued beef" was significantly higher while the frequency of intake of "fried eggs or rolled omelet," and "soy milk" was significantly lower in the high QL group. Conclusions: Based on these findings, it is evident that in healthy adults without any known underlying illnesses, psychological factors such as economic activity, occupational environment, and stress are considered to have a greater impact on their QL than are nutrient intake, blood biochemical indices, and anthropometric status.