• 제목/요약/키워드: Healthy adult

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도축우에서 Mannheimia haemolytica의 분리 및 항생제 감수성검사 (Isolation and antimicrobial susceptibility test of Mannheimia haemolytica from slaughtered cattle)

  • 변재원;김경호;이승환;이혜화;이정인;황현순
    • 한국동물위생학회지
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    • 제26권2호
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    • pp.121-128
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    • 2003
  • This study was carried out to identify and investigate antimicrobial susceptibility for Mannheimuia haemolytical which is responsible for shipping fever. Samples were collected from nasal and lung of 100 adult healthy cattle which are slaughtered in Samsung meat corporation located in Incheon metropolitan city. lung lesion index have been investigated within 0-5 range according to Shewen and Willkie(Can J Vet Res 52:30-36, 1988). Eighty-seven of 100 cattle were under normal condition with 0-1 ranges. A total of 129 strains were collected from blood and tryptic soy agar. Among these strains, 100 strains were identified with Staphylococcus, Streptococcus and enterobacteria containing E coli. Biochemical and fermentation assay of arabinose, trehalose, xylose, mannose, mannitol, lactose and salicin were tested to identify with Mannheimia sp. for 7 strains shown haemolytic activity on blood agar. Five strains were identified with Mannheimia haemolytica and 2 strains were untyped. In seasonal survey, Mannheimia sp recovered from fall to winter(5 of 7) have been highly isolated rather than those from spring to summer(2 of 7). Mannheimiz haemolytica were susceptible to antibacterials tested in this study but more resistant to oxytetracycline and streptomycin.

새로운 해열, 진통, 소염제인 HP228의 단독 또는 Morphine과의 병용투여가 제통효과에 미치는 영향 (Effects of HP228 on Analgesia Alone or in Combination with Morphine)

  • 이승구;이승훈;김태성;김현수;김광민
    • The Korean Journal of Pain
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    • 제12권1호
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    • pp.64-69
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    • 1999
  • Background: The new drug HP228 is a cytokine restraining agent with a broad spectrum of anti-inflammatory, analgesic, and antipyretic activity. Six healthy, adult, male volunteers were studied to determine the independent and interactive effects of HP228 and morphine on pain perception. Methods: Two groups of stimuli were applied to each volunteers before drug administration as control, 20 min after morphine and HP228 administration, and 20 min after combined administration of these two drugs. Two adhesive electrically-conducting pads were applied on opposite sides of the arm approximately 8 cm apart. The electrode were connected to an electrical impulse generator and 50 Hz 1 msec pulses of incrementally increasing intensity were delivered at 1 sec intervals. The analgesic endpoints were the current intensity (mA) at which the subject first detected the stimulus (THRESH), the intensity at which the stimulus was first idenfied as being painful (PAIN), and the intensity at which the subject requested that the stimulus be terminated due to discomfort (LIMIT). A second series of stimuli were applied immediately thereafter using 1-sec duration 50 Hz tetanus pulses with increasing intensities at 2~5 sec intervals. Results: There were significant differences between drug treatments (Morphine, HP228, HP228/Morphine) and control (No drugs) in any of the measurements (PAIN, LIMIT) except THRESH with the twitch and tetanus test. Conclusions: The data suggests that HP228 is an analgesic, but it does not appear to interact with morphine in an additive manner.

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일부 농촌 성인 남녀의 일상식이중 납 섭취수준과 칼슘 섭취량, 혈액 수준 및 뇨중 배설량과의 관계 (The Relationship between Lead Intake and Calcium Status in Korean Rural Adult Men and Women on Self-Selected Diet)

  • 전예숙;김애정;최미경
    • 한국식품영양학회지
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    • 제6권3호
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    • pp.211-218
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    • 1993
  • This study was carried out to estimate the dally intake of lead and the relationship among dietary In take, serum level, and urinary excretion of calcium In 30 healthy adults living In rural area of Korea (12 males and 18 females). Analyses for the nutritional status of the subjects were performed by 3-day dietary intake record, duplicated diet collection, 24-hour urine collection, and venous blood sampling. The results were as follows The mean daily intake of energy was 2,176.3kcal and 1,613.9kcal in males and (tamales of 20∼49years, and 1,914.8kcal and 1,517.9kcal in males and females of 50∼59years, respectively The ratio of carbohydrate : fat : protein was 73.4:13.6:13.0 in males and 76.4:10.3:13.3 In females. The mean daily intake of lead was 277.2Pg in males and 192.0ug in females. The mean daily intake, serum level, and urinary excretion of calcium were 491.1mg, 8.9mg/dl, and 80.7mg in males and 426.7mg, 8.8mg /dl, and 80.3mg in females, respectively. No significant correlation was found between the daily lead intake and the dietary intake, serum level, and urinary excretion of calcium. It was concluded that the daily lead intake was lower than the acceptable daily lead intake of FAO/WHO but a little higher than that of other investigations. And the daily lead intake was not level that relate to calcium status seriously.

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Midazolam 진정요법 시 Bispectral index (BIS) Monitoring 효과의 평가를 위한 혈장농도, 진정지수(Sedation Score) 사이의 상관 관계 분석 (RELATIONSHIP BETWEEN BISPECTRAL INDEX (BIS), SEDATION SCORE AND PLASMA CONCENTRATION FOR EVALUATION OF MONITORING EFFECT OF BISPECTRAL INDEX IN MIDAZOLAM SEDATION)

  • 박은진;염광원;김은석;김현정
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제29권3호
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    • pp.169-172
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    • 2003
  • Purpose : We examined the relationship between BIS, sedation score and plasma midazolam concentration to verify the usefulness of BIS to assess the patient's consciousness during sedation. Patients and Methods : Twenty-five young, healthy adult volunteers participated in this clinical study. Midazolam was administered intravenously up to 0.08 mg/kg to induce unconsciousness and we monitored the patient's physiological and conscious status until complete recovery from sedation. BIS and sedation score were measured before sedation, 10, 20, 30 minutes after midazolam administration. Plasma midazolam concentration was measured 10 minutes after midazolam administration. BIS was measured using A-2000 BISTM monitor (Aspect Medical Systems, USA) and the degree of sedation was evaluated with the sedation score. Results : The BIS score correlated with the sedation score (r = 0.676; P < 0.05). With the decreased plasma midazolam concentration, the correlation was better with sedation score (r = -0.656). Although BIS values did not correlate with calculated plasma concentration of midazolam (r = 0.467) at 10 minutes after midazolam administration, values after sedation were well distinguished from those before sedation. Conclusions : BIS is known for an effective predictor of patient's hypnotic state, and it is correlated with the sedation score. But, it doesn't always coincide with the clinical parameters of depth of sedation. So more attention is needed using BIS only during sedation, and it is advisable that the patient's consciousness is monitored with variable sedation score systems every several minutes.

천장관절 가동술이 신체중심 이동거리에 미치는 정도 (The effects of Sacroiliac joint mobilization on the Equilibrium Ability)

  • 공원태;한종만
    • 대한정형도수물리치료학회지
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    • 제11권1호
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    • pp.29-36
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    • 2005
  • The purpose of this study was to evaluate change of path length center of body on sacroiliac joint mobilization. The subjects were consisted of sixty healthy adult two decade(28 females. 32 males; mean aged 22.2) from 20 to 29. All subjects randomly assigned to the control group, sacroiliac joint mobilization group. sacroiliac joint mobilization group received sacroiliac joint mobilization for 2-3 minutes per day and three times a week during 3 weeks period. The study carried out to determine the change of path length center of body on sacroiliiac joint mobilization from July 1, 2004 through september 30, 2004. Active balancer(SAKAI EAB-100) was used to measure equilibrium ability. All measurements of each subjects were measured at pre-experiment and post-experiment. The results of this study were summarized as follows: 1. The WPL of control group, sacroiliac joint mobilization group was no significantly differences at pre-experiment but significantly reduced post-experiment(p<.05). The results of analyzed effects of WPL was significantly reduced between experiment type of control group, sacroiliac joint mobilization group according to pre-experiment and post-experiment(p<.05). 2. The UPL of control group, sacroiliac joint mobilization group was no significantly differences at pre-experiment but significantly reduced post-experiment(p<.05). The results of analyzed effects of UPL was significantly reduced between experiment type of control group, sacroiliac joint mobilization group according to pre-experiment and post-experiment(p<.05). Conclusionally these data suggest that a 3-week S-I joint mobilization improved equilibrium. Additional randomized controlled trials to more fully investigate treatment effects and factors that may mediate these effects are needed.

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재생 불량성 빈혈(Aplastic anemias) 환자의 치주 치료 증례 (Periodontal treatment of a patient with aplastic anemia)

  • 배규현;한수부;김우성;이혜아;김동균
    • Journal of Periodontal and Implant Science
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    • 제28권1호
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    • pp.187-191
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    • 1998
  • Aplastic anemia is a disease characterized by general lack of bone marrow activity; It may affect not only the red blood cells but also the white blood cells and platelets, resulting in pancytopenia. Spontaneous gingival hemorrhage is present in some cases and it is related to the blood platelet deficiency. This case report presents the periodontal treatment of a patient with aplastic anemia. A 43-year-old female was referred for continuous gingival bleeding after periodontal treatment. Periodontal findings revealed generalized gingival imflammation, oozing of blood from gingival crevice, and it was diagnosed as adult periodontitis. Root planing and extraction of the upper left third molar with poor prognosis were put into operation after elevation of the platelet count with platelet transfusion. The extraction socket was sutured with 3-0 silk. Bleeding continued even after digital compression at the upper right second premolar, second molar, and left canine areas, which presented severe inflammation. Although platelets were transfused repeatedly, platelet count did not stay elevated since survival rate of the transfused platelets were low due to alloimmunization. Thrombin gauze packing was not effective. Bleeding ceased 3 days after treatment with transfusion of donor platelets. 20 days after the treatment, the gingiva was generally healthy except upper right second premolar and lateral incisor areas. The result of periodontal treatment was good, but bleeding control after treatment was troublesome. In the periodontal treatment of patient with aplastic anemia, elevation of the platelet count with platelet transfusion seems to be the best method for hemorrhage control.

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A morphometric analysis of maxillary central incisor on the basis of facial appearance in Korea

  • Ku, Ji-Eun;Yang, Hong-So;Yun, Kwi-Dug
    • The Journal of Advanced Prosthodontics
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    • 제4권1호
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    • pp.13-17
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    • 2012
  • PURPOSE. We aimed to identify a more esthetic width-to-length ratio by analyzing maxillary central incisor of Korean adult population. Information regarding tooth ratio in the Korean population may be useful to clinicians when restoring anterior teeth. MATERIALS AND METHODS. A total of 40 men and 40 women were included in this study. The NON-MEDIA group included 40 non-celebrities, who were healthy and 25 to 39 years old, with normal dentofacial appearance. The MEDIA group consisted of 40 celebrities selected only on the basis of their soft-tissue facial appearance. The facial photographs of 40 celebrities were collected from the Internet websites. The width and length of the maxillary central incisor were measured using Adobe $Photoshop^{(R)}$ 7.0, a software for analysis, measurement and edition of photographs. Data were analyzed statistically using the Independent t-test at 5% statistical significance level. RESULTS. The mean ratio for the MEDIA group was 0.77, whereas that of the NON-MEDIA group was 0.88. The difference between the two groups was statistically significant. No significant gender differences were found in the width-to-length ratio in MEDIA group. In NON-MEDIA group, however, there were significant differences between female and male. CONCLUSION. After analyzing maxillary anterior teeth of Korean adults, our results were in accordance with the general Western standards of esthetics. A dentist restoring the natural look and beauty of teeth will have to consider those standards.

외이도용적에 따른 외이도공명의 변화 (Resonance Changes in the External Auditory Canal Associated with the Ear Canal Volume)

  • 최아현;이미소;최아름;허승덕
    • 말소리와 음성과학
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    • 제1권3호
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    • pp.151-154
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    • 2009
  • The external ear generates resonance gain because of anatomical characteristics. The ear canal resonance is influenced by the length and volume of the ear canal, the pinna, the concha cavity, the body trunk, and the speed of sound wave. This study is focus on the influence of the volume of ear canal. 17-healthy-adult (32 ears) were participated. They did not have any medical and ear disease history. The maximum resonance frequency of the ear canal was 2675 (${\pm}265$) Hz at azimuth $0^{\circ}$ and 2784 (${\pm}268$) Hz at azimuth $45^{\circ}$. The resonance gain was 18.1 (${\pm}3.9$) dB at azimuth $0^{\circ}$ and 17.9 (${\pm}3.8$) dB at azimuth $45^{\circ}$, respectively. The ear canal volume was 0.78 (${\pm}0.2$) cc and 1.32 (${\pm}0.8$) cc including static compliance. The ear canal resonance was changed depending on the ear canal volume. It was also statistically correlated at azimuth $0^{\circ}$ (p=0.038) and $45^{\circ}$ (p=0.013), respectively. The resonance gain was not correlated with the ear canal volume. The change of resonance frequency according to the ear canal volume will be useful information in the field of audiological rehabilitation especially for hearing aids fitting. In addition, we expected this study can provide the basic information for the study of the external ear resonance characteristics.

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소아치과 환자에서의 세보플루란을 이용한 흡입 심진정법 (Inhalational Deep Sedation Using Sevoflurane in Pediatric Dental Patients)

  • 이원호;김영재;장기택;이상훈;서광석;김현정;염광원;박창주
    • 대한치과마취과학회지
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    • 제4권2호
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    • pp.90-95
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    • 2004
  • Background: Sevoflurane, a rotatively new inhalational anesthetic. has non-pungent odor and is less reluctant to pediatric patients. The purpose of this study is to examine the feasibility of sevoflurane in inhalational sedation instead of the nitrous oxide for short and simple dental treatments in pediatric patients. Patients and Methods: Fifteen healthy children, whose dental treatment was abandoned due to their little or no cooperation, were selected with their caregivers' written permission. Deep sedation was induced and maintained with oxygen and 1-5% sevoflufane via specially designed nasal mask. Blood pressure, heart rate, oxygen saturation, and electrocardiogram were monitored at 3-nin interval. A dental anesthesiologist, who was independent of dental treatments, was wholly responsible for the sedation procedure. Post-sedation complications and operator's and caregiver's acceptability of this type of inhalational sedation were also investigated. Results: The systolic and diastolic blood pressure, heart rate, and oxygen saturation was significantly depressed during the deep sedation using sevoflurane (P < 0.05). No severe post-sedation complications were found, however, bradycardia was reported in 3 patients. Almost all the operators and caregivers answered that they would adapt this sedation procedure again if possible. Conclusion: In this study, inhalational deep sedation using sevoflurane for dental treatments was found to be very useful. Furthermore, the application of sevoflurane to conscious sedation for pediatric and adult dental patients should be added.

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정상견에서 전방 췌장십이장 동맥의 초음파학적 혈관 저항지수 (Ultrasonographic Resistive Index of the Cranial Pancreaticoduodenal Artery in Normal Conscious Dogs)

  • Eom, Ki-Dong;Lee, Hae-oon;Seong, Yun-sang;Lee, Jeong-min;Lee, Jong-won;Oh, Tae-ho
    • 한국임상수의학회지
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    • 제20권3호
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    • pp.274-277
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    • 2003
  • 임상적으로 건강한 비글견 17두와 췌장염으로 진단된 5두(요크셔테리어 3두, 토이푸들 2두)의 견에서, 화학보정 없이 전방 십이지장동맥(cranial pancreaticodudenal artery: cPDA) 혈관저항지수(resitive index: RI)를 측정하고 이를 비교 평가하였다. RI 측정을 위해 이중 펄스 색도플러 초음파와 11-MHz 선형 위상차 배열 탐촉자를 이용하였다. 췌장염견(0.75$\pm$0.04)견의 평균 RI는 정상견(0.63$\pm$0.04)과 비교하여 유의성(t = 5.79, p = 0.001)있게 증가된 소견을 보였다. 췌장염에 이환 또는 의증 환축에서는 cPDA의 RI 평가 또한 보조적 진단 가치가 있음을 확인하였다.