• Title/Summary/Keyword: Healthy adult

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Pre-Natal Epigenetic Influences on Acute and Chronic Diseases Later in Life, such as Cancer: Global Health Crises Resulting from a Collision of Biological and Cultural Evolution

  • Trosko, James E.
    • Preventive Nutrition and Food Science
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    • v.16 no.4
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    • pp.394-407
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    • 2011
  • Better understanding of the complex factors leading to human diseases will be necessary for both long term prevention and for managing short and long-term health problems. The underlying causes, leading to a global health crisis in both acute and chronic diseases, include finite global health care resources for sustained healthy human survival, the population explosion, increased environmental pollution, decreased clean air, water, food distribution, diminishing opportunities for human self-esteem, increased median life span, and the interconnection of infectious and chronic diseases. The transition of our pre-human nutritional requirements for survival to our current culturally-shaped diet has created a biologically-mismatched human dietary experience. While individual genetic, gender, and developmental stage factors contribute to human diseases, various environmental and culturally-determined factors are now contributing to both acute and chronic diseases. The transition from the hunter-gatherer to an agricultural-dependent human being has brought about a global crisis in human health. Initially, early humans ate seasonally-dependent and calorically-restricted foods, during the day, in a "feast or famine" manner. Today, modern humans eat diets of caloric abundance, at all times of the day, with foods of all seasons and from all parts of the world, that have been processed and which have been contaminated by all kinds of factors. No longer can one view, as distinct, infectious agent-related human acute diseases from chronic diseases. Moreover, while dietary and environmental chemicals could, in principle, cause disease pathogenesis by mutagenic and cytotoxic mechanisms, the primary cause is via "epigenetic", or altered gene expression, modifications in the three types of cells (e.g., adult stem; progenitor and terminally-differentiated cells of each organ) during all stages of human development. Even more significantly, alteration in the quantity of adult stem cells during early development by epigenetic chemicals could either increase or decrease the risk to various stem cell-based diseases, such as cancer, later in life. A new concept, the Barker hypothesis, has emerged that indicates pre-natal maternal dietary exposures can now affect diseases later in life. Examples from the studies of the atomic bomb survivors should illustrate this insight.

A Study on Experiences of Caring for Children with Autistic Disorder - Focused on Experiences of Parents of the Adult Children - (자폐성 장애인을 자녀로 둔 부모의 돌봄 경험에 관한 연구 - 성인기 자녀를 둔 부모의 경험을 중심으로 -)

  • Lim, Haeyoung;Song, Keumyeol
    • Korean Journal of Social Welfare
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    • v.67 no.3
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    • pp.227-252
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    • 2015
  • This study conducted in-depth interviews of seven parents with autistic adults and analyzed them using qualitative case study methods in order to understand overall meaning of care experiences of parents with autistic adult children. Thus, four key topics which are 'experience of embracement', 'experience of anticipation', 'experience of despair', 'experience of resistance' were constructed. Under these key topics, 12 subcategories which are 'accepting reality', 'positive experience', 'gradual improvement', 'desire to provide better quality of life', 'expectation towards the society', 'strenuous lives', 'psychological exhaustion', 'predicted anxiety', 'defensive attitude', 'distrust of social welfare', 'confronting injustice', 'active behaviors' were constructed. According to the analysis, care experiences of parents with autistic adults are not segmentary, but they are intertwined which make them more dynamic. Thus, easing their despair, empowering positiveness to them, and assisting them to have healthy resistant voice are needed to support the parents with autistic adults. Based on the analysis, we suggest an intervention plan to support autistic adults and their parents.

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Body Type Characteristics and Classification of Men in Their 20s for Development of Fitted Sloper (피티드 원형 개발을 위한 20대 남성의 체형 특성 및 유형화)

  • Kim, Kyung-A;Kim, Myoung-Ok
    • Fashion & Textile Research Journal
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    • v.18 no.2
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    • pp.235-243
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    • 2016
  • This study is a preliminary study to suggest a distinguished fitted sloper according to body types. To this end, this study classified body types of men in their 20s in an attempt to examine the characteristics of each type. A total of 842 adult men of age 20 to 29 were studied by using the direct measurement data taken in the 6th Size Korea. The subjects' body types were classified based on 48 measurements. We extracted a total of six factors that characterized the body types of adult men in their 20s: horizontal size, vertical length, shoulder development, trunk area length, hip area length and shoulder slope. Result of the cluster analysis, the body shapes of men in their 20s were classified into four types. We developed the overlapped silhouettes for each of the four body types and compared the front and side shapes to clearly identify the differences of each body types. The findings of this study indicated that Korean adult men in their 20s can be classified into the big inverted triangular type that represents healthy and muscular men, the small inverted triangular type that represents short and skinny men, the triangular type that represents men with abdominal obesity, and the rectangular type that represents men that are fat overall, with a fairly even distribution of each body type.

Xenografting of the Human Vitrified Ovarian Tissues into the Immune Deficient Animal (사람 난소조직의 초자화 냉동보존과 면역결핍 동물에의 이식)

  • Lee, Kyung-Ah;Yoon, Se-Jin;Lee, Sook-Hyun;Shin, Chang-Sook;Choi, An-Na;Cho, Yong-Seon;Yoon, Tae-Ki;Cha, Kwang-Yul
    • Clinical and Experimental Reproductive Medicine
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    • v.27 no.2
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    • pp.145-149
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    • 2000
  • Objective: The present study was conducted to evaluate the viability of germ cells from the adult and fetal ovarian tissues after vitrification followed by xenografting. Method: The human adult ovarian tissues were obtained from 33 years old patient, and the fetal ovarian tissues were obtained from 22 weeks and 25 weeks in gestation. Ovarian tissues were cryopreserved by vitrification with 5.5 M ethylene glycol (EG 5.5) and 1.0 M sucrose as cryoprotectants. Adult and fetal ovarian tissues were pre-equilibrated with EG 5.5 at room temperature for 10 and 5 minutes, respectively and plunged into liquid nitrogen immediately. Frozen-thawed tissues were xenografted into NOD-SCID mice to evaluate the viability and capacity for further growth of the primordial follicles. Grafts were recovered from the recipients 4 weeks after transplantation and histological analysis was accomplished. Result and Conclusion: Grafts recovered 4 weeks after transplantation contained less number of oocytes and primordial follicles compared to that of the fresh tissues. Survived follicles were mainly primordial and intermediary with larger diameter and more granulosa cells. It is confirmed that 1) the ovarian tissues were healthy and the germ cells were survived after vitrification, and 2) the survived fetal primordial follicles after vitrification resumed the growth in the xenografts.

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Awareness analysis for popularization of temple food in monks (스님들을 대상으로 한 사찰음식의 대중화에 대한 인식도 조사 분석)

  • Hwang, Eun Gyeoung;Kim, Soo Jung;Kim, Byung Ki;Lee, Jea Young
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.6
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    • pp.1217-1224
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    • 2015
  • The survey and analysis of preferences for temple food known to health promotion and prevention of adult diseases aimed at popularization of the monks living in Daegu Gyeongbuk and Busan Gyeongnam inspections are as follows. Monks have been recognized as healthy food (42.2%), and expected contribution of health promotion, such as prevention of adult diseases in the popularization of temple food (74.7%), it was better traditional cooking method, and recognize improvement of nutritional supplement (36.7%). Also, meat used (68.8%) and ohsinchae (57.8%) were not necessary for popularizing. In particular, difference was statistically significant in accordance with the number of monks that live with sex (nuns) (p <0.01). The results suggest that monks agree with popularization of temple food. However, monks stick to traditional cooking method and not in used meat and ohsinchae.

Analysis of Studies on Physical Activity Program for Adults and Elderly in Korea (신체활동 프로그램에 대한 국내 연구 논문 분석)

  • Park, Jee-Yeon;Kwon, Sang-Min;Kim, Na-Hyun
    • Journal of Digital Convergence
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    • v.11 no.11
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    • pp.651-659
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    • 2013
  • Purpose: This study was to analyze research reports published in Korea on physical activity for adult. Method: Based on inclusion criteria, 11 research reports were included in this review. Published year of selected articles was between 1990 and 2012. Eleven studies were analyzed by guidelines of the physical activity program done by experimental and quantitative research. Result: The characteristics of objects were mostly of non disease adult, over 65 years old, and female. Most educational content were about physical activity understanding, diet, nutrition. A large percentage of outcome indicators were body composition, physical function. Conclusion: Various types of physical activity program in Korea were performed by researchers. Therefore, we need to develop the standard protocol, to add educational intervention, and to study cost effectiveness of healthy.

The Effect of Various Wheelchair Handle Directions on Muscle Activity of Adult Male Trunks When Climbing Ramps

  • Ahn, Su-Hong;Lee, Su-Kyong
    • PNF and Movement
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    • v.17 no.3
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    • pp.379-389
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    • 2019
  • Purpose: This study examined the effects of wheelchair handle directions on the trunk muscle activity of adult males when climbing ramps. It also evaluated the wheelchair attendant's physical discomfort during tasks. Methods: Healthy males aged over 20 years were chosen and the direction of wheelchair handle grip was randomly selected. The grips included a general grip with ulnar deviation, a medial grip with wrist pronation, and a neutral grip with a neutral wrist. The trunk muscle activity was measured using surface electromyography. Furthermore, the physical discomfort of wheelchair attendants was subjectively evaluated using the Borg CR-10 Scale, which rates the perceived exertion. In addition, the SPSS 18.0 program was used perform repeated measure ANOVA to compare muscle activity and subjective discomfort during the interventions. The contrast test was also conducted with a significance level (α) of 0.05. Results: There was significant difference between the general grip and the medial grip in the rhomboid major muscle and the lumbar erector spinae muscle (p<0.05). In addition, there was significant difference between the general grip and the neutral grip in the rhomboid major muscle and the lumbar erector spinae muscle (p<0.05). Further, there was significant difference between the general grip and the neutral grip in subjective discomfort (p<0.05). Conclusion: In this study, adult male trunk muscle activity and subjective discomfort were lowest when using the neutral grip while climbing ramps. Accordingly, we suggest that neutral grips will help improve the function of the musculoskeletal system and reduce the subjective discomfort by putting less strain on the trunk muscles and maximizing efficiency with less force.

Nutritional Value of Mealworm, Tenebrio molitor as Food Source

  • Ravzanaadii, Nergui;Kim, Seong-Hyun;Choi, Won-Ho;Hong, Seong-Jin;Kim, Nam-Jung
    • International Journal of Industrial Entomology and Biomaterials
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    • v.25 no.1
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    • pp.93-98
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    • 2012
  • Nutrition value of mealworm, Tenebrio molitor was analyzed due to increasing demand of usage as a protein source for domestic animals and even further for human consumption. The purpose of the present work was to determine the chemical compostion of the Tenebrio molitor larvae, adult that were maintained under standard condition for further usage of mass-rearing system and its exuvium, and excreta. Tenebrio molitor, larvae, adult, exuvium and excreta contained 46.44, 63.34, 32.87, and 18.51% protein respectively, suggested that even excreta could be used as an additional supplement in food recycling process. This protein was also rich in amino acids such as Isoleucine, leucine and Lysine which all met the nutritional value recommended by the Food and Agriculture Organization. Fatty acid composition was detected with high component of oleic acid (C18:1), along with linoleic acid (C18:2) and palmitic acid (C16) in all adult, larvae, exuvium and excreta. These oleic acid (C18:1), linoleic acid (C18:2) and palmitic acid (C16) components were the same or even highly contained in excreta of mealworm 22.29, 47.19 and 19.17% respectively. Longer chains of unsaturated fatty acids consisted of two to three double bonds are known as healthy product was recognized in large amount. These results show new ways to consume mealworms and its waste for animal and human consumption.

A Preliminary Study for the Application of Michigan Alcoholism Screening Test-Geriatric Version in Korea (한국에서 노인용 미시간주정의존선별검사의 적용을 위한 예비연구)

  • Cheon, Jin-Sook;Oh, Byoung-Hoon;Choi, Young-Tai
    • Korean Journal of Biological Psychiatry
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    • v.6 no.1
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    • pp.102-110
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    • 1999
  • Objectives : The alcohol dependence in elderly people has been prevalent because of increase in geriatric population. However, it is difficult to find out alcohol dependence in the aged, because they have less specific clinical features as compared with adult alcoholics. The aims of this study were to screen alcohol dependence among elderly Koreans and to know the clinical characteristics of Korean delerly alcoholics. Methods : The questionnaires translated into Korean such as Michigan Alcoholism Screening Test(MAST-K), the Brief MAST and the MAST-Geriatirc Version (MAST-KG) were used to screen alcohol dependence in the elderly alcoholic inpatients aged over 60(N=43), adult alcoholic inpatients within 20-59 Yrs of age(N=60), which were compared with age matched normal healthy aged(N=18) or adult controls(N=45). The demographic data such as sex, age, education, occupation, socioeconomic status, marital status, numbers of children, dwelling and religion as well as alcohol history such as duration of alcohol drinking, onset age, family history, impulsivity, somatic illness and motivation were also obtained to identify characteristic features of Korean aged alcoholics by structured interviews. Results : 1) The aged alcoholics had the charateristic features of more in males, lower age, low education levels, more in blue-collar workers, lower socioeconomic class, more in single, few babies, more living alone, having no religion without statistical significance. 2) The onset age of alcohol dependence was significantly higher in the aged alcoholics($45.3{\pm}13.6Yrs$) than in the adult alcoholics($27.7{\pm}8.7Yrs$)(p<0.0001). The duration of problematic alcohol drinking was significantly longer in the aged alcoholics($22.0{\pm}15.1Yrs$) than in adult alcoholics($14.2{\pm}8.4Yrs$)(p<0.01). Otherwise, there were no significant difference between aged and adult alcoholics in the family history, imulsivity, somatic illness and motivation. 3) The mean score of the MAST-K was significantly higher in the aged alcoholics($20.6{\pm}5.4$) than in the normal aged($6.7{\pm}4.4$)(p<0.0001), which was significantly lower than in the adult alcoholics($26.2{\pm}8.0$) and in normal adult controls($9.5{\pm}3.2$)(p<0.05). The mean score of the Brief MAST was significantly lower in the aged alcoholics($9.3{\pm}3.5$) than in the adult alcoholics($14.5{\pm}6.6$)(p<0.0001). The mean score of the MAST-KG was significantly higher in the aged alcoholics($10.6{\pm}3.5$) than in the normal aged($4.8{\pm}4.3$)(p<0.0001). The former was significantly lower than in the adult alcoholics($12.9{\pm}4.3$)(p<0.005), and the mean score was $4.5{\pm}2.8$ in normal adult controls. 4) The items which showed statistically significant differences between aged alcoholics and normal aged controls could be found in 10 items of the MAST-K(items 2, 3, 4, 5, 11, 14, 17, 21, 22 and 23), 2 items of the Brief MAST(items 2 and 9), and 7 items of the MAST-KG(items 6, 13, 18, 19, 22, 23 and 24)(p<0.01). Conclusions : The scores of the MAST-K, the Brief MAST and the MAST-KG were significantly lower in the aged alcoholics than those in the adult alcoholics (p<0.05). The statistically significant differences between aged alcoholics and normal aged controls could be found in 10 items of the MAST-K, 2 items of the Brief MAST and 7 items of the MAST-KG. Therefore, a briefer rating scales around 10 items are needed to screen alcohol dependence among Korean elderly people.

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Effect of an Application of Pelvic Compression Belt on the Strength of Hip Flexor in Healthy Young Adult (골반벨트 적용이 건강 성인의 고관절 굴곡근 근력에 미치는 영향)

  • Yoon, Dong-Joon;Kim, Suhn-Yeop;Lee, Eun-Hee;Kim, Se-Lim;Oh, Duck-Won
    • Journal of Korean Physical Therapy Science
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    • v.15 no.4
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    • pp.35-42
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    • 2008
  • Background : To assess the effect of a pelvic compression belt on the strength of hip flexor in healthy young individuals. Study design: Pre- and post-treatment measurement design on one factor was used. Methods : 30 healthy volunteers (male: 15, female: 15) participated in this study. Dynamometer was used to measure the strength of hip flexor, and measurements were performed before and after the application of the pelvic compression belt at neutral position of hip joint and at 30 cm raised position from floor with straight leg in supine. Results : After the application of the pelvic compression belt, the strengths of hip flexor measured at both positions were significantly increased when compared with before the application (p<.05). However, at neutral position of hip joint and at 30cm raised position from floor, there were significantly different in the changing patterns in the strengths of hip flexor between men and women (p>.05). Conclusion : The findings suggest that the pelvic compression belt is helpful in strengthening hip muscles. With easy application, it is sufficiently feasible for clinical use.

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