Ectopic expression of CDX2 in the stomach is closely associated with chronic Helicobacter pylori (H. pylori) infection and intestinal metaplasia. Whether CDX2 has tumor suppression or tumorigenesis potential remains to be elucidated. In this study, we investigated the association between the CDX2 G543C polymorphism (silent mutation) and the risk for H. pylori-induced gastric atrophy and cancer as well as H. pylori infection, using 454 Japanese subjects undergoing a health checkup and 202 gastric cancer patients. The frequency of the minor allele was the same as previously reported in China, but different from that reported in England. CDX2 G543C was not associated with risk of H. pylori infection, gastric atrophy, or gastric cancer, although the point estimate for non-cardiac differentiated gastric cancer as compared to controls with gastric atrophy was 2.22 (95%CI=0.17-29.4). In conclusion, our results indicate that the CDX2 G543C polymorphism is unlikely to affect the H. pylori infection-gastric atrophy-gastric cancer sequence.
The objective of this study was to analyze the relationship between blood pressure and serum mineral concentration in hypertension patients subjected to dehydration. The data were collected and analyzed for 7,109 patients who visited a hospital for their health checkup from 2011 till 2015. Respondents were classified into four groups depending upon their state of hypertension and dehydration: control group (no hypertension and no dehydrated), dehydrated group, hypertension group, and dehydrated with hypertension group. Hypertension group was found to have higher levels of serum sodium, calcium, and uric acid than the normal group, whereas the dehydrated group was found to have higher levels of serum sodium and potassium than the normal group. In effect, no significant correlation was directly observed between the hypertension group and dehydration group. However, there were significant negative correlations between dehydration of the old-aged group and their serum mineral concentrations, which are reportedly related to hypertension. Thus, dehydration prevention measures in the elderly over 65 could mitigate hypertension problems.
Few studies have utilized observational methods in the field of couple research even though using self-report questionnaires is prone to the subjective biases of the reporter. This study validates the Marital Interaction Coding System-Global (MICS-G), a global version of the well-established microanalytic observational coding system, Marital Interaction Coding System (MICS). Participants in the study consisted of 30 married couples with varied levels of marital adjustment who visited one of the Healthy Family and Multicultural Family Support Centers in Seoul, either for couple therapy or the "Marriage Checkup"program. Ten-minute problem-solving discussions were rated by two undergraduate student raters who were trained for 10 hours. Interobserver agreement based on percentage agreement and intraclass correlation coefficients showed a high level of agreement between raters in establishing interrater reliability. Convergent validity was established by: correlations among marital adjustment, psychological aggression, mental health, and MICS-G categories of conflicts, validation, invalidation, facilitation, and withdrawal. MICS-G categories also were successful in discriminating between distressed and nondistressed couples, which provides evidence of discriminant validity for MICS-G. This study showed that MICS-G is a promising method for researchers to observe couple interactions in a more cost-effective way. Methodological issues and practical applications are also discussed.
Kahng, Dong Hwahn;Kim, Gwang Ha;Park, Sang Gyu;Lee, So Jeong;Park, Do Youn
Clinical Endoscopy
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v.51
no.6
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pp.587-590
/
2018
Schwannomas are uncommon neoplasms that arise from Schwann cells of the neural sheath. Gastrointestinal schwannomas are rare among mesenchymal tumors of the gastrointestinal tract, and only a few cases have been reported to date. Duodenal schwannomas are usually discovered incidentally and achieving a preoperative diagnosis is difficult. Schwannomas can be distinguished from other subepithelial tumors on endoscopic ultrasonography; however, any typical endosonographic features of duodenal schwannomas have not been reported due to the rarity of these tumors. Immunohistochemistry is essential to distinguish schwannomas from gastrointestinal stromal tumors and leiomyomas. We report a case of duodenal schwannoma found incidentally during a health checkup endoscopy. On endoscopic ultrasonography, this tumor was suspected as a gastrointestinal stromal tumor; therefore, the patient underwent laparoscopic wedge resection of the tumor. Histopathology and immunohistochemistry confirmed that the duodenal lesion was a benign schwannoma.
Objectives : The oral care during early childhood plays an important role to maintain sound oral health during adulthood. As the number of children's using child care facilities is on the rise recently, the children's oral health awareness and behavior of the educators at nurseries and kindergartens are to be examined. Methods : A self-recording survey was conducted on 194 educators at the nurseries and kindergartens in Chungnam region. Results : The most frequently given snack was milk, 91.8 percent of the facilities had children brush their teeth, 63.4 percent made them apply fluoride and 56.2 percent kept children's toothbrushes in an ultraviolet rays sterilizer. There was a meaningful difference in the awareness of the necessity to educate children about oral health according to the offer of the opportunity to apply fluoride (p<0.05). A meaningful difference was found in the recognition of the necessity to educate children according to their grade (p<0.05) and to train teachers themselves (p<0.05). The most desirable persons in charge of oral health education were dentists in health centers (46.9%) in order. The more experience in teaching they have had (p<0.05), when they're married (50.5%) (p<0.05) and when they're not homeroom teachers (52.6 percent), the more regular checkups they have had (p<0.05). As for the importance of oral health and the results of regular checkups, those who had answered 'very important'(42.4%) showed higher rate of regular checkup (p<0.05) than those who had answered 'important'(23.9%). When teachers have the experience to get trained about oral care (96.3%), the practice frequency of brushing teeth was proved to become higher (p<0.05). Conclusions : The educators for children should recognize the importance of oral health education, educate children to practice oral health care, and the environment and systematic foundation should be established which the educators manage effectively.
The purpose of this study was to examine the demographic characteristics, oral health awareness and oral health behavior of 1,356 Korean senior citizens based on the fourth raw materials of the 2008 national health and nutrition survey, and to analyze their DMFS, DMFT and FS-T indexes, which were oral health indicators. The findings of the study were as follows: 1. The mean DMFS index of the Korean senior citizens was 26.62, and their average DMFT index was 6.76. Their mean FS-T index was 21.51. 2. Out of the demographic characteristics of the Korean elderly people, education made statistically significant differences to the DMFS(p<0.05) and FS-T(p<0.001) indexes, and whether they worked or not made statistically significant differences to the DMFT(p<0.01), DMFS(0.001) and FS-T(0.001) indexes. There were no significant gaps according to gender, age and presence or absence of a spouse. 3. The oral health awareness of the Korean senior citizens(subjective oral health status, whether to need a dental treatment, concern for oral health and mastication) had no statistically significant relationship to their DMFS, DMFT and FS-T indexes. 4. Among the oral health behaviors of the Korean elderly people, whether they got a dental checkup over the past year made statistically significant differences to the DMFT(p<0.01), DMFS(p<0.001) and FS-T (p<0.001) indexes, and there were statistically significant gaps in the DMFT(p<0.010, FS-T(p<0.01) and DMFS(p<0.001) indexes according to yesterday's toothbrushing frequency. The time when they went to a dentist made a significant difference to the FS-T(p<0.01) index only.
Journal of the Korean Applied Science and Technology
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v.35
no.4
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pp.1413-1420
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2018
This study was conducted to provide the information for the promotion of oral health in nursing students. The subjects were 207 in female students for self-administered questionnaires. The percentage of subject to visit dental clinic was 64.3%, to Regular checkup was 25.9%, cure of caries was 23.5% for last one year. The percentage of reasons not treated 'less importance' were 12.6%, 'fear of the dental clinic' was 10.6%. The average number of brushing teeth were 3.1. 56.0% students brush their teeth for two ~ three minutes. But intention of visit to the dentist were 'only when treated' was 51.7%, 'only when there is pain' was 10.1%. The intention of oral education was 54.6%, the content of the desired education 'whitening' were 34.5%, 'prevention of bad breath' was 19.2%. Dental health information acquisition path 'internet' were 42.0%, 'family or friends' was 25.6%. Susceptibility was 2.47 points, severity was 2.00 points, benefit was 4.03 points in oral health belief. Compared to students who needed dental treatment but did not receive treatment, oral health beliefs were higher among those who were treated(p<.001), students with cavities showed a higher level of oral health belief than those without cavities(p<.001). There was significant corelation between 'number of caries' and susceptibility(r=.330, p=.002), severity(r=.25, p=.019). The result should be reflected in the development of effective program for nursing students' oral health care.
The purpose of this study was to examine various factors influencing the needs of Seoul's newly implemented outreach community services for older adults, and to suggest the direction of the outreach community health services in Seoul. A multi-level regression was conducted using data collected by face-to-face interviews from 1,000 individuals aged 65 and 70 in 17 districts, where participated in the Seoul's outreach community services. The results demonstrated that socioeconomic status (higher income and living alone), health status (having multiple chronic conditions and depression, lower health literacy), limited experience of the outreach community services, and low government trust at the individual level were associated with higher unmet need for the community outreach services. In addition, shorter participation period of the outreach services and financial independency at the district level were associated with higher unmet need for the services. The findings from this study implies the need for improving the quality of services by focusing on vulnerable groups such as individuals with lower income and worse health status. In addition, the outreach community health services may need to target individuals aged 66 to increasing efficiency of the services through utilizing results of life-cycle health checkup by the National Health Insurance Corporation.
This study is to get preliminary data for an effectiveness evaluation of abdominal examination and improvement of it. Abnormal cases of abdominal ultrasonography are classified by sex, frequency, diagnosis and age. 4,924 examinees were included at a university hospital of health promotion center from January to December in 1999. The results are as follows. 1. According to the distribution of sex, there are more male patients(55.0%) than females patients(48.0%). For men, 40's showed the highest percentage among examinees. For women, 50's were the highest. 2. The reason that they visited the health promotion center was that 'they wanted to check their health status'. This answers were reported the highest(59.3%). 3. Patients that had abnormal cases of abdominal ultrasonography were 48.3%. Liver, kidney, gallbladder showed the highest percentage of abnormal cases in order of organs. Additionally, abnormal cases were discovered in liver cases. 4. According to the frequency of abnormal cases among examinees, the slight fatty liver were the highest regardless of sex. Men had the slight fatty liver, kidney simple cyst, liver calcification and liver simple cyst in order of abnormal cases. Women showed the slight fatty liver kidney simple cyst, kidney calcification, liver simple cyst, and blood vessel tumor in order of abnormal cases. 5. For the abnormal cases of liver by sex and age, the 50's reported the highest number of abnormal cases in men(299 patients). In addition, 60's had the highest of disease rata 47.8%. For women, 50's reported the highest number of abnormal cases(361 patients). Over 70's patients had the highest of disease rata 52.6%. For kidney, men and women showed the highest number of abnormal cases -62 vs 44 respectively. Over 70's patients had the highest percentage of disease rata-23.2% vs 14.0% respectively. For gallbladder, the number of abnormal cases were the most in men's 60's (31 patients) and in women's in the same age group (32patients). Disease showed the highest percentage in men's 60's(7.6%) and in women's 70's (14.0%). 6. According to malignant tumor, 17patients were liver cancer, 2patients stomach ca and 1pt kidney cancer. 7. The relationship between the malignant tumor and the examination motive was that 'they wanted to check their health status(41.0%)' and 'regular checkup (24.0%)'.
Kim, Yang-Hyun;Han, Kyungdo;Son, Jang-Won;Lee, Seong-Su;Oh, Sang Woo;Kwon, Hyuk-Sang;Shin, Soon-Ae;Kim, Yeon-Yong;Lee, Won-Young;Yoo, Soon Jib;Taskforce Team of the Obesity Fact Sheet of the Korean Society for the Study of Obesity
Journal of Obesity & Metabolic Syndrome
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v.26
no.1
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pp.23-27
/
2017
Background: In Korea, the prevalence of obesity has steadily increased, and the socioeconomic burden of obesity has increased along with it. In 2015, the National Health Insurance Service (NHIS) signed a memorandum of understanding with the Korean Society for the Study of Obesity (KSSO), providing limited open access to its databases so that the status of obesity and obesity management could be investigated. Methods: Using NHIS databases, we analyzed nationwide population-based studies for obesity using the definition of obesity (body mass index ${\geq}25kg/m^2$) in subjects over the age of 20. Age and sex standardization were used for all data. Results: The KSSO released the 'Obesity Fact Sheet 2016' using the 2006-2015 NHIS Health Checkup database. The prevalence of obesity steadily increased from 28.7% in 2006 to 32.4% in 2015, and the prevalence of abdominal obesity also steadily increased from 18.4% in 2009 to 20.8% in 2015. The prevalence of class II obesity steadily increased from 2006 to 2015, such that the total prevalence was 4.8% in 2015 (5.6% in men and 4.0% in women). The highest prevalence of obesity was found in Jeju Island, while the lowest prevalence was found in Daegu City. The highest prevalence of abdominal obesity was also found in Jeju Island, while the lowest prevalence was found in Gwangju City. Conclusion: Based on the Obesity Fact Sheet 2016, a strategy for reducing the prevalence of obesity is needed, especially in Korean men.
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