• Proceedings of the Korean Society of Toxicology Conference
• /
• 2001.05a
• /
• pp.126-126
• /
• 2001

The purpose of this study was to investigate the acute(4 hrs) and repeated-dose(6 hrs a day, 5 days a week, 8 weeks) toxic effects of 1-bromopropane(1-BP) on Sprague-Dawley (SD) rats which were treated by inhalation. The results were as follows ;(omitted)

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.29 no.2
• /
• pp.226-235
• /
• 2019

Objectives: The purpose of this study was to investigate whether there were differences in manufacturing industry worker's health issues depending on job stress, fatigue, and health and safety services. Methods: The purpose of the questionnaire survey and its contents were explained to manufacturing industry health personnel, and the questionnaires were collected from 666 workers from 17 manufacturing workplaces. Questionnaires with missing data were excluded from the analysis so a total of 632 questionnaires were included. Results: Overall, 74.1% of the respondents had experienced health issues during the preceding month. The factors affecting worker health were number of workers(OR=1.000034, p=.013), job demand(OR=1.82, p=.009), MFS(OR=1.85, p=.003), provision of safety & health information(OR=1.85, p=.048), wearing protector(OR=2.58, p=.021). Conclusion: It is necessary to strengthen the safety and health education to mitigate hazardous and risk factors. Employers should provide health managers in charge of safety and health education to control workplace risk factors. In case of small businesses, it may be necessary to strengthen safety and health education in existing worker health centers and government support projects.

• Annals of Occupational and Environmental Medicine
• /
• v.34
• /
• pp.5.1-5.10
• /
• 2022

Background: Some epidemiological studies have estimated exposure among flight attendants with and without breast cancer. However, it is difficult to find a quantitative evaluation of occupational exposure factors related to cancer development individually in the case of breast cancer in flight attendants. That is, most, if not all, epidemiological studies of breast cancer in flight attendants with quantitative exposure estimates have estimated exposure in the absence of individual flight history data. Case presentation: A 41-year-old woman visited the hospital due to a left breast mass after a regular check-up. Breast cancer was suspected on ultrasonography. Following core biopsy, she underwent various imaging modalities. She was diagnosed invasive ductal carcinoma of no special type (estrogen receptor positive in 90%, progesterone receptor positive in 3%, human epidermal growth factor receptor 2/neu equivocal) with histologic grade 3 and nuclear grade 3 in the left breast. Neoadjuvant chemotherapy was administered to reduce the tumor size before surgery. However, due to serious chemotherapy side effects, the patient opted for alternative and integrative therapies. She joined the airline in January, 1996. Out of all flights, international flights and night flights accounted for 94.9% and 26.2, respectively. Night flights were conducted at least four times per month. Moreover, based on the virtual computer program CARI-6M, the estimated dose of cosmic radiation exposure was 78.81 mSv. There were no other personal triggers or family history of breast cancer. Conclusions: This case report shows that the potentially causal relationship between occupational harmful factors and the incidence of breast cancer may become more pronounced when night shift workers who work continuously are exposed to cosmic ionizing radiation. Therefore, close attention and efforts are needed to adjust night shift work schedules and regulate cosmic ionizing radiation exposure.

• Safety and Health at Work
• /
• v.3 no.4
• /
• pp.305-305
• /
• 2012

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.11 no.3
• /
• pp.198-205
• /
• 2001

Many reactive dyes have been used in occupational settings without knowing their toxicity and health hazard information. To investigate the toxicity of reactive dye, C.I.No. Reactive Red 195 was exposed to male and female Sprague Dawley rats by inhalation for 28 days. The rats were exposed C.I.No. Reactive Red 195 for 6 hrs per day and 5days per week. The concentrations for the inhalation exposure were 0, 10, 40 and $160mg/m^3$. After 4 weeks of exposure, rats were examined for exposure related changes through pathology, blood biochemistry and hematology. There were no dose related changes including clinical signs, body weight and relative organ weight changes, hematological and biochemical and histopathological findings. The results indicate that no observed adverse effect level (NOAEL) of 28 days inhalatrion toxicity test for C.I.No. Reactive Red 195 was $160mg/m^3$.

• Journal of the Korea Safety Management & Science
• /
• v.15 no.2
• /
• pp.47-53
• /
• 2013

This study is aimed to investigate the occupational safety and health management of contractor company in the car industry. The questionnaire survey was conducted on the suppliers and contractors of car industry. Data were collected from 10 contractor companies and their 291 contractor companies(each outside and inside company). From the survey result, it was found that the level of all-round safety and health management is above the average. To strengthen the relationship for safety and health management, it is needed that the supplier company employ the person in exclusive charge to support contractor. Also it is needed the active support of the contractor company and needed that the supplier company employ the person in exclusive charge to support contractor. Finally, Many of the problems associated with the safety and health management by strengthening contractor company responsibility will have to be solved simultaneously.

• Safety and Health at Work
• /
• v.7 no.4
• /
• pp.326-330
• /
• 2016

Background: The Nordic Safety Climate Questionnaire-50 (NOSACQ-50) was developed by a team of Nordic occupational safety researchers based on safety climate and psychological theories. The aim of this study was to develop and validate the Persian version of NOSACQ-50 and assess the score of safety climate on a group of workers in a steel company in Iran. Methods: The Persian version of NOSACQ-50 was distributed among 661 employees of a steel company in Qazvin Province (Iran). Exploratory factor analysis (EFA) and confirmatory factor analysis were used to determine the dimensions of the questionnaire. The reliability of the questionnaire was assessed using Cronbach ${\alpha}$ coefficient. Pearson correlation test was applied to investigate the correlation between different dimensions. Results: The results of EFA showed that the Persian version of NOSACQ-50 consisted of six dimensions. The Cronbach ${\alpha}$ coefficient of the questionnaire was 0.94. The mean score of safety climate in all dimensions was 2.89 (standard deviation 0.60). Conclusion: The Persian version of NOSACQ-50 had a satisfactory validity for measuring safety climate in the studied Iranian population.

• Proceedings of the Korean Society of Toxicology Conference
• /
• 2001.05a
• /
• pp.134-134
• /
• 2001

Cutting oils are complex mixtures of hydrocarbons, comprising of certain fractions of mineral oil, which are being frequently used as lubricating and heat transferring agents in various machine and tool industries. We investigated an acute and 2 weeks repeated irritation studies of two cutting oils (Cimperial 1010 as water-soluble cutting oil, and MSN 120 as insoluble cutting oil) using guinea pigs.(omitted)

• Annals of Occupational and Environmental Medicine
• /
• v.35
• /
• pp.52.1-52.13
• /
• 2023

Background: In 2019, the International Agency for Research on Cancer re-evaluated the carcinogenicity of night-shift work and reported that there is limited evidence that night-shift work is carcinogenic for the development of prostate cancer. Therefore, in 2020 and 2021, the Korean Epidemiologic Investigation Evaluation Committee concluded that 2 cases of prostate cancer were occupational diseases related to the night-shift work. Here, we report the 2 cases of prostate cancer in night-shift workers which were first concluded as occupational diseases by the Korean Epidemiologic Investigation Evaluation Committee. Case presentation: Patient A: A 61-year-old man worked as a city bus driver for approximately 17 years, from 2002 to 2019, and was exposed to night-shift work during this period. In March 2017, the patient was diagnosed with high-grade prostate cancer through core-needle biopsy after experiencing stinging pain lasting for 2 months. Patient B: A 56-year-old man worked as an electrician and an automated equipment operator in a cement manufacturing plant for 35 years from 1976 to 2013 and was exposed to night-shift work during this period. In 2013, the patient was diagnosed with high-grade prostate cancer through core needle biopsy at a university hospital because of dysuria that lasted for 6 months. Conclusions: The 2 workers were diagnosed with high-grade prostate cancer after working night shifts for 17 and 35 years respectively. Additionally, previous studies have reported that high-grade prostate cancer has a stronger relationship with night-shift work than low or medium-grade prostate cancer. Therefore, the Korean Epidemiologic Investigation Evaluation Committee concluded that night-shift work in these 2 patients contributed to the development of their prostate cancer.

• Proceedings of the Safety Management and Science Conference
• /
• 2009.04a
• /
• pp.79-91
• /
• 2009

The government separated and established the industrial safety and health law from the Labor Standard law since 1981 to promote the labor's working environment and to improve the conditions of laborers. The government made a lot of effort to discharge the industrial safety and health law by continuous revision of the law thereafter. it is, however, difficult to establish clear-cut lines of authority and responsibility due to the fact that the substantial application of the industrial safety and health law is adapted by enterprise's autonomous management. There are frequent industrial disasters on the small and medium enterprises which have financial difficulty and it means this causes much more social cost. Finally, for the improvement of laborer's safety, health and working environment in the small and medium enterprises we need to raise the effectiveness of the industrial safety and health law through enhancing a government-office's administration and surveillance with the changing mind of a business proprietor. On this paper, we research on the actual condition of the administration, inspection and regulation of safety and health by means of the industrial safety and health law. Thereafter we analyze how much the Korea Occupational Safety & Health Agency and vicarious businesses of safety & health management help. we used the survey method to gather data from 380 laborers directly and analysed the data by SPSS v17.0.