• 운동영양학회지
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• 제24권2호
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• pp.1-5
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• 2020

[Purpose] Lactate has several beneficial roles as an energy resource and in metabolism. However, studies on the effects of oral administration of lactate on fat metabolism and glycogen synthesis are limited. Therefore, the purpose of the present study was to investigate how oral administration of lactate affects fat metabolism and glycogen synthesis factors at specific times (0, 30, 60, 120 min) after intake. [Methods] Male Sprague Dawley (SD) rats (n = 24) were divided into four groups as follows: the control group (0 min) was sacrificed immediately after oral lactate administration; the test groups were administered lactate (2 g/kg) and sacrificed after 30, 60, and 120 min. Skeletal muscle and liver mRNA expression of GLUT4, FAT/CD36, PDH, CS, PC and GYS2 was assessed using reverse transcription-polymerase chain reaction. [Results] GLUT4 and FAT/CD36 expression was significantly increased in skeletal muscle 120 min after lactate administration. PDH expression in skeletal muscle was altered at 30 and 120 min after lactate consumption, but was not significantly different compared to the control. CS, PC and GYS2 expression in liver was increased 60 min after lactate administration. [Conclusion] Our results indicate that exogenous lactate administration increases GLUT4 and FAT/CD36 expression in the muscle as well as glycogen synthase factors (PC, GYS2) in the liver after 60 min. Therefore, lactate supplementation may increase fat utilization as well as induce positive effects on glycogen synthesis in athletes.

• 대한간호학회지
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• 제54권2호
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• pp.193-210
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• 2024

Purpose: The objective of this study was to develop a predictive model for the sexual experiences of adolescents using the random forest method and to identify the "variable importance." Methods: The study utilized data from the 2019 to 2021 Korea Youth Risk Behavior Web-based Survey, which included 86,595 man and 80,504 woman participants. The number of independent variables stood at 44. SPSS was used to conduct Rao-Scott χ² tests and complex sample t-tests. Modeling was performed using the random forest algorithm in Python. Performance evaluation of each model included assessments of precision, recall, F1-score, receiver operating characteristics curve, and area under the curve calculations derived from the confusion matrix. Results: The prevalence of sexual experiences initially decreased during the COVID-19 pandemic, but later increased. "Variable importance" for predicting sexual experiences, ranked in the top six, included week and weekday sedentary time and internet usage time, followed by ease of cigarette purchase, age at first alcohol consumption, smoking initiation, breakfast consumption, and difficulty purchasing alcohol. Conclusion: Education and support programs for promoting adolescent sexual health, based on the top-ranking important variables, should be integrated with health behavior intervention programs addressing internet usage, smoking, and alcohol consumption. We recommend active utilization of the random forest analysis method to develop high-performance predictive models for effective disease prevention, treatment, and nursing care.

• 한국농촌건축학회논문집
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• 제26권2호
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• pp.47-56
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• 2024

Through an examination of future societal development, it was found that the demographic structure is gradually aging, thus placing higher demands on elderly welfare centers. This study conducted surveys on three elderly day care centers in the entire region, aiming to enhance the pivotal role of elderly day care centers in the welfare facilities for the elderly. The current usage status, interior architectu/ral evaluations, and questionnaire surveys of these centers were analysed. The results of investigation into the architectural environment of the elderly day care centers showed that in terms of physical environment, smaller-scale centers did not lag behind larger ones in internal facilities, but larger-scale centers excelled in spatial utilization. Furthermore, the results of questionnaire survey results revealed correlations between family relationships, health status, level of assistance required, and satisfaction with facility usage, while no correlation was found between usage time, health status, and satisfaction with facility usage. This study conducted basic investigations such as architectural and physical surveys, and questionnaire surveys on elderly day care centers. Based on the survey results, future design practices should continuously explore and innovate to meet the needs of an aging society, further improve the community care system, provide more comprehensive and meticulous services for the elderly, and lay the foundation for enhancing the quality of life for the elderly and providing comfortable services.

• 보건행정학회지
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• 제5권2호
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• pp.35-69
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• 1995

The managerial environment of hospitals in Korea characterized by low levels of medical insurance fees is worsening by increasing government regulations as to the utilization of medical services, rising costs of labor, material, and medical equipments, growing patient expectations concerning the quality of services, and escalating competitions among large hospitals in the market. Hospitals should seek for their survival strategies in this harsh environment and they should have information about costs of their products in doing so. However, it has not been available due to the complexity of the production process of hospital services. The objectives of this study were to develop a service-based cost accounting model and to apply the developed model to a study hospital to obtain cost information of hospital services. A model commonly used for the job-order product cost accounting in the manufacturing industry was modified for the use in hospitals in Korea. Actual costs, instead of standard costs, incurred to produce a unit of services during a given period of time were estimated in the model. Data required to implement the model included financial information, statistics for the allocation of supportive cost center costs to final cost centers, statistics for the allocation of final cost center costs to services, and the volume of each services charged to patients during a study period. The model was executed using data of a university teaching hospital located in Seoul for the fiscal year 1992. Data for financial information, allocation statistics fo supportive service costs, and the volume of services, most of them in electronic form, were available to the study. Data for allocation statistics of final cost center costs were collected in the study. There were 15 types of evaluation and management service, 2, 923 types of technical service, and 2, 608 types of drug and material service charged to patients in the study hospital during the fiscal year 1992. Labor costs of each of seven types of pesonnel, material costs of 611 types of drugs and materials, and depreciation costs of 212 types of medical equipments, miscellaneous costs, and indirect costs incurred in producing a unit of each services were estimated. Medical insurance fees for basic services such as evaluation and management of inpatients and outpatients, injection, and filling prescriptions, and for operating procedures were found to be set lower than costs. Infrequent services which use expensive medical equipments showed negative revenuse as well. On the other hand, fees for services not covered by the insurance such as CT, MRI and Sonogram, and for laboratory tests were higher than costs. This study has a significance in making it possible for a hospital to obtain cost information for all types of services which produced income based on all types of expenses incurred during a given period of time. This information can assist the management of a hospital in finding an effective cost reduction strategy, an efficient service-mix strategy under a given fee structure, and an optimum strategy for within-hospital resource allocations.

• 한국산학기술학회논문지
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• 제17권12호
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• pp.205-217
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• 2016

본 연구는 일개 경로당 이용 노인의 웃음치료 경험의 본질과 의미를 이해하기 위하여 밴 매넌(Van Mannen)의 해석학적 현상학적 연구방법을 적용하였다. 연구참여자는 경로당에서 웃음치료를 경험했으며 연구참여에 동의한 총 12명(남 4명, 여 8명)이며, 연구참여자와의 면담과 문학 및 예술작품 등을 참조하여 자료를 수집하였다. 노인들의 웃음치료 경험에 대한 자료 분석을 통하여 노인들이 지향하는 삶은 건강한 삶(몸의 기운을 회복함, 기분이 맑아짐), 행복한 삶(스트레스를 해소함, 잡념을 잊게 함, 일상의 활력소가 생김, 함께 웃어서 배가되는 즐거움, 추억을 되살리며 젊어짐), 희망하는 삶(고통을 잊고 긍정적 마음을 가짐, 기대하는 일이 생김)의 구조로 의미화 됨을 알 수 있었다. 건강한 삶은 신체, 심리적으로 건강행위를 추구하는 삶의 근본적인 원동력에 대한 체험이고 행복한 삶은 타인과의 관계형성과 공감을 통해 기쁨을 창조하는 삶이며 마지막으로 희망하는 삶은 다양한 상실의 고통을 극복하고 삶을 긍정적으로 통합하는 체험이다. 결론적으로 노인들에게 웃음치료는 노인들의 건강, 대인관계 및 삶을 통합하도록 하였다. 따라서 노인들에게 웃음치료를 활용할 수 있다면 노인들의 독립심과 자존감을 향상하는데 도움이 될 것이다.

• 한국응급구조학회지
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• 제13권1호
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• pp.61-72
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• 2009

Purpose : This study was conducted to understand the unforeseen phone calls placed through the 1339 emergency medical communication system by residents of the Gwangju/Jeonnam area during the Lunar New Year and Chuseok holidays. Methods : A descriptive research method was implemented using SPSS to analyze 9,047 reported and received consultation phone calls made during the 2008 Lunar New Year holiday (February 6-10) and the 2008 Chuseok holiday (September 13-15) for frequency and percentages. Results : Among the general characteristics of subjects during the Lunar New Year and Chuseok holidays, an examination of the distribution for gender showed more men than women and the distribution for age showed most subjects were thirties, followed by forties, and finally under ten years of age. According to the status of situational calls during the Lunar New Year holiday most were used for in the following order : providing resource information, misdialing and prank calls, and additional consultations. According to the status of situational calls during the Chuseok holiday most were used for in the following order : providing resource information, additional consultations, misdialing and prank calls. According to region most came from Gwangju Metropolitan City Bukgu, followed by Yeosu, Suncheon, and Mokpo in Jeonnam. According to callers, the majority were non-medical persons. According to time most were made between 9:01 and 12:00, while the fewest were made during 3:01 and 6:00. According to treatment department most were made in the following order : internal medicine, pharmacy, and pediatrics. Most medical resource information provided regarded areas outside the callers location. Conclusion : Emergency medical technician will play a central role in the emergency medical information system in the near future.

• 한국수산과학회지
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• 제53권3호
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• pp.464-470
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• 2020

This study was conducted to replace fish meal (FM) with three plant proteins (soybean meal, soy protein concentrate, and wheat gluten) in diets for growing olive flounder Paralichthys olivaceus. The control diet was formulated to contain 65% sardine FM and four other replacement diets were formulated to replace FM with the plant proteins by 25, 30, 35 and 40% (designated FM25, FM30, FM35 and FM40, respectively). The replacement diets were added with three essential amino acids (lysine, methionine and threonine) to meet their requirements for the fish. Olive flounder (initial average weight, 96.8±0.2 g) were randomly distributed into 20 tanks (425 L each) at a density of 25 fish per tank. Four replicate groups of fish were fed one of the diets two times daily for 15 weeks. At the end of the feeding trial, no significant differences were found among all the fish groups in growth performance, feed utilization, nonspecific immune responses and hematological health parameters. Thus, this result indicates that the plant proteins with the three limiting amino acids could replace FM up to 40% in diets for growing olive flounder.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권1호
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• pp.61-69
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• 2022

Purpose: Studies in adults have shown an increasing incidence of Clostridioides difficile infection (CDI) in patients hospitalized with acute pancreatitis (AP). There is lack of epidemiological data on CDI and its impact on hospitalized pediatric patients with AP. Methods: We analyzed the National Inpatient Sample and Kids' Inpatient Database between the years 2003 and 2016 and included all patients (age <21 years) with a primary diagnosis of AP using specific International Classification of Diseases codes. We compared clinical outcomes between children with CDI and those without CDI. Our primary outcome was severe AP and secondary outcomes included length of stay and hospital charges. Results: A total of 123,240 hospitalizations related to AP were analyzed and CDI was noted in 0.6% of the hospital. The prevalence rate of CDI doubled from 0.4% (2003) to 0.8% (2016), p=0.03. AP patients with CDI had increased comorbidities, and also underwent more invasive surgical procedures, p<0.05. AP patients with CDI had a higher in-hospital mortality rate and increased prevalence of severe AP, p<0.001. Multivariate regression models showed that CDI was associated with 2.4 times (confidence interval [CI]: 1.91 to 3.01, p<0.001) increased odds of severe AP. CDI patients had 7.24 (CI: 6.81 to 7.67, p<0.001) additional hospital days while incurring $59,032 (CI: 54,050 to 64,014, p<0.001) additional hospitalization charges. Conclusion: CDI in pediatric patients with AP is associated with adverse clinical outcomes and increased healthcare resource utilization. Further studies are needed to elucidate this association to prevent the development of CDI and to improve outcomes.

• 환경영향평가
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• 제24권5호
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• pp.444-455
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• 2015

연안준설행위에 따른 연안준설토의 활용 및 처분에 관련된 현 체계 및 법적 기준의 고찰을 통해서 문제점을 진단하고 개선방안을 제시하고자 하였다. 현행 제도상 연안준설토는 활용과 처분의 기준을 준설토사유효활용기준에 따라 구분하고 있으나 매립이 완료된 투기장을 부지로써 활용함으로서 처분과 활용의 개념이 모호하다. 또한 준설토의 매립재활용에 있어서 토양오염우려기준을 적용하는 것은 연안준설토의 토양특성, 기준항목의 차이, 실험방법의 차이 등을 고려해볼 때 적합하지 않은 것으로 판단된다. 하지만 현행의 유효활용기준은 매립재 활용에 있어 문제점이 있으므로 다음과 같이 개선이 요구된다. 첫째, 매립재 활용을 위한 용도구분이 필요하며, 둘째, 인체위해성을 고려한 2단계 체계의 기준농도를 제시할 필요가 있다. 또한 해역이용협의과정에서 연안준설토를 투기장에 투기시 주변해역에 미치는 영향파악과 저감대책을 포함한 평가가 이루어져야 할 것이다.

• 농촌의학ㆍ지역보건
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• 제28권2호
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• pp.107-122
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• 2003

만성질환자들의 보완요법 이용률과 이용양상을 알아보기 위하여 보건소에 등록된 고혈압, 당뇨병, 만성관절염 환자를 대상으로 하여 2001년 1월 3일부터 1개월간 각 질환별로 200명씩 총 600명에게 지난 12개월간의 보완요법이용실태에대하여직접면담조사를실시하였다. 지난 1년 동안 전체 대상자의 47.5%가 보완요법을 이용하였는데, 고혈압 환자는 35.0%, 당뇨병 환자는 44.6%, 관절염 환자는 62.9%가 보완요법을 이용하여 관절염 환자의 이용률이 가장 높았다. 보완요법 이용률은 대상자의 일반적 특성에 따라서 거의 유의한 차이를 보이지 않았다. 보완요법 이용자 중 고혈압 환자는 약초요법(31.0%)과 침요법(29.6%)을 많이 이용하였고, 당뇨병 환자는 식이요법(57.5%)과 약초요법(35.1%)을 그리고, 관절염 환자는 침요법(85.0%)과 약초요법(34.7%)을 많이 이용하였다. 보완요법 이용자중 2종류 이상을 이용한 사람은 36.8%였고, 고혈압 환자가 18.3%, 당뇨병 환자가 24.1%, 관절염 환자가 55.9%로서 관절염 환자가 여러종류의 보완요법을 이용하였다. 가장 많이 이용한 보완요법을 종류별로 보면 침술이 47.0%로 가장 높은 빈도를 보였고, 그 다음이 한약(26.3%), 건강보조기구(21.8%), 민간요법(21.4%), 물리치료(9.5%), 건강보조식품(8.4%), 약초(7.7%), 수지침(3.2%), 단전호흡(1.1%), 기공치료(0.7%)의 순이었다. 보완요법을 이용한 장소로는 한의원이 42.8%로 가장 많았고, 이용한 이유로서는 치료를 위해서가 61.8%, 증상완화가 26.0%로 대부분의 환자들이 치료와 증상완화를 위해서 이용하였으며, 지난 1년간 보완요법 이용에 지출한 비용은 9만원 이하가 40.3%로 가장 많았고, 50만원 이상도 31.2%이었다. 보완요법 이용 후 56.1%가 만족하다고 대답했고, 6.0%는 부작용을 경험했다고 하였다. 보완요법을 이용한 사람들의 74.0%가 계속 이용하겠다고 하였으며, 56.1%는 다른 사람에게 권유할 의향이 있다고 하였다. 정통의료와 비교한 보완요법의 이점으로는 33.5%가 심리적으로 안정감을 준다, 21.2%는 몸을 보호해 준다, 19.2%가 효과가 좋다라고 하였다. 또한 조사대상자 가운데 보완요법에 대한 교육을 희망하는 사람은 34.0%였다. 이상의 연구결과에서 볼 때 만성질환자들의 상당수(47.5%)가 지난 1년간 자신들의 건강문제를 해결하기 위하여 다양한 종류의 보완요법을 이용하였고, 비록 부작용 경험률이 6.0%정도 되지만 보완요법에 대한 만족도가 비교적 높고, 계속적으로 이용할 의사가 높기 때문에 보건기관이나 의료인들의 적극적인 관심이 요구되며, 부작용이 없고 건강증진에 도움이 되는 다양한 보완요법 프로그램 개발에 노력을 기울려야 할 것으로 생각된다. 그리고 보안요법의 효능를 확인하는 노력이 계속되어야 하고, 적절한 가격을 유지할 수 있는 제도적 장치도 필요하다고 생각된다.