• 약학회지
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• 제54권2호
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• pp.142-149
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• 2010

Development of alternative testing methods for the replacement of hazardous reagents with less hazardous ones is strongly enforced because exposure of human and environment to hazardous reagents are restricted and hazardous reagents are gradually prohibited from using in various testing methods. Thus, in this study, we developed 8 monographs from the Korean Pharmaceutical Codex by substituting the use of the hazardous reagents including ICH class 1 such as benzene, chloroform and dioxane to the use of less toxic ones like ICH class 2 or 3 reagents. We also improved their qualification and quantification performance. Among 8 monographs, the 6 newly developed TLC methods for the identification of nifedipine, oxolamine citrate, ketoprofen lysinate, chlorquinaldol, retinol acetate, and riboflavin showed a clear spot of corresponding material without any interference in spite of the replacement with ICH class 2 or 3 reagents. For the quantification of domperidone and trimebutine, HPLC methods were developed for the substitution of UV/VIS spectrometry and titrimetry, respectively. These HPLC methods were validated for the linearity, recovery, reproducibility, and inter-laboratory variations. In conclusion, the newly developed methods could be expected to become valuable tools for revising the Korean Pharmaceutical Codex.

• 대한안전경영과학회지
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• 제22권2호
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• pp.73-82
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• 2020

IEC 60079-10-1 edition 2.0, the global standard for hazardous area classification, was newly revised in 2015. There are many differences compared to the previous edition 1.0 version, first released in 2008, so it has caused confusion in the industry. In case of edition 1.0, the hazardous area extent can be derived through the mathematical formula, but in case of edition 2.0, there was the problem that the exact hazardous area extent was not known because of the mathematical formula of the plot for applying the hazardous area extent was not presented. In this study, we converted the plot introduced in edition 2.0 to CAD format and derived the plot as the mathematical equations. Through this, we suggest the hazardous area extent formula of three states (heavy gas, diffusive, jet). As the IEC committee did not provide the mathematical formula of the hazardous area extent according to the release characteristic, it is impossible to apply the exact hazardous area extent. In this study, a mathematical approach was derived for the plot introduced in edition 2.0, which can reduce the confusion of the applying hazardous area extent.

• 한국위험물학회지
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• 제6권2호
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• pp.68-76
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• 2018

This study aims to provide a methodological framework to estimate the travel demand of hazardous materials transporting vehicles by link and analyze daily traffic patterns on an expressway to develop safety roadway management strategies. Traffic volume of hazardous material vehicles is counted through the on-site investigation at twenty-five tollgates on the expressway, and their demands by a link are predicted through origin-destination flows estimation. The result shows that the number of the domestic hazardous materials vehicles is approximately 51,207 vehicles per day and it indicates that hazardous materials transport vehicles account for 1.5% of total daily traffic on the internal expressway and 6.2% of total cargo traffic volumes. This study roughly estimated how many hazardous materials vehicles pass through the expressway segment. Thus it is expected to be utilized for establishing a systematic highway management strategy in the future by calculating the traffic volume of the hazardous material vehicles traveling on the interstate expressway.

• 한국위험물학회지
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• 제6권2호
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• pp.62-67
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• 2018

It is very important to classify explosion hazardous area in order to prevent an accident explosion. In order to prevent such a explosion, the Industrial Safety and Health Standards Rules stipulates the establishment and management of explosion hazards in accordance with the criteria set by the Korean Industrial Standards. This study has investigated the range of the explosion hazardous area according to various hole sizes, pressures, vapor densities, and wind velocities in the outdoor flammable liquid tank using KS C IEC-60079-10-1 $2^{nd}$ Ed.(=IEC CODE) and PHAST. The results show that the explosion hazardous areas by IEC CODE have circle shapes. However, the areas by PHAST show ellipse shapes. The different of the explosion hazardous areas increases with the increase of wind velocity.

• 수산경영론집
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• 제52권4호
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• pp.29-43
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• 2021

This study investigated whether there is a correlation between the occurrence of hazardous substances such as vibrio, norovirus, radioactivity, shellfish posion, hepatitis A, etc. and media reports, and whether the occurrence of hazardous substances and media reports affect the production, distribution and consumption of aquatic products. The main research results are as follows. First, it can be seen that there is a difference in the relationship between the occurrence of hazardous substances and media reports according to hazardous substances. Second, it suggests seen that the occurrence of hazardous substances and media reports can have a negative effect on the production and the prices of aquatic products. Third, it was found that the occurrence and reporting of hazardous substances had different effects on the distribution margin of aquatic products due to the complexity and rigidity of the distribution structure. Fourth, consumers feel a threat to aquatic products safety and significantly reduce consumption when hazardous substances occur. There is a possibility that concerns about one item may lead to a decrease in consumption of domestic and imported aquatic products that are not related at all to the occurrence of hazardous substances. In conclusion, aquatic products are exposed to various hazardous substances such as vibrio, norovirus, radioactivity, shellfish posion, and hepatitis A. It was found that the occurrence of hazardous substances and its media reports could cause damage to the fishery sector.

• 한국가스학회지
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• 제15권1호
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• pp.68-73
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• 2011

The systems in Korea regarding manufacture, storage, transport and use of hazardous materials are regulated by the related laws and ordinances. The number of accident from hazardous materials has recently decreased but the size of accident has increased according to the hazardous substances are greatly consumed and delivered. The results of analysis showed that most of accidents are caused by human problems and occurred frequently at unauthorized facilities. It is suggested that workers should be trained more and the strict regulation on unauthorized facilities is needed to reduce the accidents caused by hazardous materials.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제16권1호
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• pp.1-12
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• 2016

In this paper, we propose an approach that efficiently builds regional hazardous weather prediction models based on past weather data. Doing so requires finding the proper weather attributes that strongly affect hazardous weather for each region, and that requires a large number of experiments to build and test models with different attribute combinations for each kind of hazardous weather in each region. Using our proposed method, we reduce the number of experiments needed to find the correct weather attributes. Compared to the traditional method, our method decreases the number of experiments by about 45%, and the average prediction accuracy for all hazardous weather conditions and regions is 79.61%, which can help forecasters predict hazardous weather. The Korea Meteorological Administration currently uses the prediction models given in this paper.

• 한국화재소방학회논문지
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• 제21권1호
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• pp.29-36
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• 2007

본 연구에서는 국내에서의 위험물 사고 현황을 분석함으로써 화재안전성 및 화재의식 측면에서의 취약요인을 파악하였고, 위험물 안전관리자를 선임해야 하는 위험물제조소등의 종류 및 규모가 현재 법적으로 어떻게 규정되어 있는지 조사하였으며, 또한 한국소방안전협회에서 주관하는 위험물안전관리자 강습교육을 받는 사람들을 대상으로 한 설문조사를 바탕으로 위험물 안전관리자 강습교육에 대한 보다 효율적이고 체계적인 강습교육과정을 마련코자 하였다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 춘계학술대회 논문집
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• pp.1174-1179
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• 2007

Train collision and derailment are types of accident that happen with low probability of occurrence but could lead to disastrous consequences including multiple life losses. Risk assessment of the accidents are typically performed per their hazardous events, which are defined as events that cause accidents. This study classifies the train collision and derailment based on the relevant hazardous event, and investigates the causes related to the hazardous events. Finally, the relation of the causes, hazardous events, and the accidents are defined.

• International Journal of Advanced Culture Technology
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• 제11권3호
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• pp.346-357
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• 2023

The purpose of this study is to suggest improvement plans for prevention regulations by reflecting the toxicity, fire and explosion effects of hazardous materials factories and surrounding areas using an off-site consequence assessment program. Regarding the effects of the hydrogen cyanide leak accident, which is the 1st petroleum of the 4th class flammable liquid, Areal Locations of Hazardous Atmospheres (ALOHA) program was used to compare and analyze the extent of damage effects for toxicity, overpressure, and radiation. As a result, the toxicity was analyzed to exceed 5km in the area with Acute exposure guideline level (AEGL)-2 concentration or higher, the overpressure was 103m in the range of 1 psi or more, and the radiant heat was analyzed to be 724m in the range of 2kw/m² or more. Toxicity and radiation affected the area outside the hazardous material storage area, but the overpressure was limited to the inside of the hazardous material storage area. Therefore, we propose to improve the safety management of hazardous materials by conducting a risk assessment for hazardous materials and reflecting the results in internal and external emergency response plans to prepare prevention regulations.