• Preventive Nutrition and Food Science
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• v.10 no.4
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• pp.344-348
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• 2005

Fucoidans, high-molecular-weight sulfated polysaccharides extracted from brown seaweeds, have various biological activities. Here we examined whether fucoidan could ncrease the immunomodulation and proliferation capacity of cells in vitro. When peritoneal macrophages were treated with various concentrations of fucoidan $(1\~100{\mu}g/mL)$ for 24 hours, NO production was significantly increased. In addition, exposure of macrophages to $10{\mu}g/mL$ of fucoidan induced a phagocytic activity. Treatment of neuroblastoma cells (SK-N-SH) with fucoidan enhanced cell proliferation and NO production in a concentration-dependent manner. These results indicate that fucoidan has both immunomodulatory and cell proliferative properties, and may thus be a candidate for development as an immunomodulating agent.

• Geomechanics and Engineering
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• v.17 no.1
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• pp.97-107
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• 2019

Based on the results of Han et al. (2016), in the failure zone ahead of the tunnel face it can be obviously identified that a shear failure band occurs in the lower part and a pressure arch happens at the upper part, which was often neglected in analyzing the face stability of shield tunnel. In order to better describe the collapse failure feature of the tunnel face, a new improved failure mechanism is proposed to evaluate the face stability of shield tunnel excavated in layered soils in the framework of limit analysis by using spatial discretization technique and linear interpolation method in this study. The developed failure mechanism is composed of two parts: i) the rotational failure mechanism denoting the shear failure band and ii) a uniformly distributed force denoting the pressure arch effect. Followed by the comparison between the results of critical face pressures provided by the developed model and those by the existing works, which indicates that the new developed failure mechanism provides comparatively reasonable results.

• Korean Journal of Environmental Agriculture
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• v.17 no.3
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• pp.227-233
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• 1998

To mitigate the methane emission from rice paddy fields, effects of nitrogen fertilizers source and cultural patterns were evaluated on silty loam soils. And a pot experiment was carried out to find out the effects of nitrogen fertilizers on soil pH, Eh, sulfate concentration of soil water in flooded soil. In transplanting cultivation, the total methane emission depending on fertilizers was $32.9gm^{-2}$ for urea ; $30.3gm^{-2}$ for ammonium sulfate ; $26.4gm^{-2}$ for coated urea. Methane emitted in direct seeding on dry soil was $24.7gm^{-2}$ for urea ; $16.7gm^{-2}$ for ammonium sulfate : and $22.8gm^{-2}$ for coated urea. Thus, the methane emission rate of direct seeding on dry soil was 29.7% lower than transplanting. According to the nitrogen fertilizers, the methane emission rate by ammonium sulfate and coated urea were reduced 18.4 and 15.9% in comparison with urea, respectively. In pot experiments, pH in flooded soils depending on nitrogen fertilizers dereased in order of urea > coated $urea{\fallingdotseq}no$ fertilizer > ammonium sulfate and the order was coincided with that of total $CH_4$ emission from flooded soil. Soil Eh was highest in ammonium sulfate application followed by coated urea, no fertilizer, urea. And sulfate concentrations of soil water were in order of ammonium sulfate > coated urea > urea > no fertilizer.

• Journal of Ocean Engineering and Technology
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• v.33 no.5
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• pp.400-410
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• 2019

In this study, the numerical code for the 3D nonlinear dynamic analysis of an SLWR (Steel Lazy Wave Riser) was developed using the lumped mass line model in a FORTRAN environment. Because the lumped mass line model is an explicit method, there is no matrix operation. Thus, the numerical algorithm is simple and fast. In the lumped mass line model, the equations of motion for the riser were derived by applying the various forces acting on each node of the line. The applied forces at the node of the riser consisted of the tension, shear force due to the bending moment, gravitational force, buoyancy force, riser/ground contact force, and hydrodynamic force based on the Morison equation. Time integration was carried out using a Runge-Kutta fourth-order method, which is known to be stable and accurate. To validate the accuracy of the developed numerical code, simulations using the commercial software OrcaFlex were carried out simultaneously and compared with the results of the developed numerical code. To understand the nonlinear dynamic characteristics of an SLWR, dynamic simulations of SLWRs excited at the hang-off point and of SLWRs in regular waves were carried out. From the results of these dynamic simulations, the displacements at the maximum bending moments at important points of the design, like the hang-off point, sagging point, hogging points, and touch-down point, were observed and analyzed.

• The Korean Journal of Financial Management
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• v.20 no.2
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• pp.151-180
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• 2003

We examine the interdependence of the major Asia-Pacific stock markets including S&P 500, FTSE 100, Kualar Lumpur Composite, Straits Times, Hang Seng, NIKKEI 225 and KOSPI 200 from October 4, 1995 to March 31,2000. The analysis employs the vector-auto-regression, Granger causality, impulse response function and variance decomposition using daily returns on the national stock market indices. The findings in this paper indicate that the volatilities of all countries has grown after IMF crisis, while there is no significance in cointegration test of both total period and sub-periods. This result implies that investors are able to get abnormal returns by investment diversification according to the portfolio theory. We find that while the effect from NIKKEI 225 to others is relatively weak, the interdependence from S&P 500 to other countries is strong. Also we find that the strong effect from Straits Times to Hang Seng exists. This study suggests that there is slight feedback relation between KOSPI 200 and Kualar Lumpur Composite, Straits Times, Hang Seng stock market.

• Korean Journal of Plant Resources
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• v.24 no.3
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• pp.298-303
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• 2011

A large number of edible seaweeds are consumed by the coastal peoples of Asia. Some of them are used in traditional remedies in many parts of the world. In this study we investigated effects of supplementation with ethyl acetate extracts of the brown alga Eisenia bicyclis (EBE) on rat macrophage to evaluate the possibilities as immune-modulators. Twelve male SD rats were divided into two groups and the treatments were as follows: A, no Eisenia bicyclis extract (EBE) intake and distilled water ; B, oral supplemented with EBE 200 mg/kg. After 5 weeks of supplementation, rats were sacrificed to assess the effect on peritoneal macrophage functions. We showed no increasing effects on tumoricidal activity, phagocytic activity and NO production in macrophages in EBE supplementation group. However, EBE supplementation suppressed NO-iNOS production and p65 translocation into the nucleus in LPS-stimulated macrophages. Overall, these results suggest that the supplementation of EBE might have an anti-inflammatory effects on NO-iNOS production in macrophages throughout the inhibition of NF-${\kappa}B$ activation.

• Journal of Korean Society of Water and Wastewater
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• v.26 no.2
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• pp.257-264
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• 2012

The concept of a non-contact type of UV disinfection system was introduced in this study. UV lamps and their quartz sleeves hang over the water surface and there is no interface between the sleeve and water. Obviously, there is no fouling. Based on optical laws and other UV distribution models, a detail mathematical model for a non-contact type UV disinfection system was developed in this study. Pathway length of UV light in a non-contact type photoreactor is longer than that in a submerged type photoreactor because the light is more refractive while passing through 3 interfaces of medium. But the pathway length passing through the water media is not significantly longer than that in a submerged type photoreactor so, the absorption of UV light by water is not significantly different from the other system. Due to the reflection effect, UV intensity is rapidly decreased as the horizontal distance from the light source is increased. The reflective attenuation in a non-contact type photoreactor is higher than that in a submerged type photoreactor. These mean that the short photoreactor is advantageous than the narrow-long photoreactor for the non-contact type photoreactor in an optical point of view.

• Journal of Korean Society of Water and Wastewater
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• v.13 no.4
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• pp.35-44
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• 1999

In this study, it was attempted to remove nitrate and carbon in a single-stage reactor using acetate as substrate. Hybrid type upflow sludge baffled filter reactor was adopted using anaerobic sludge. Sludge bed in the bottom of reactor was intended to remove carbon and nitrate by denitrification and methanogenesis. And floating media in the upper part of reactor were intended to remove remaining carbon which was not removed due to the inhibition of nitrogen oxide on methane producing bacteria. The reactor removed over 96% of COD and most of nitrate with volumetric loading rate of $4.0kgCOD/m^3{\cdot}day$, hydraulic retention time of 24hr, 4,000mgCOD/L, and $266mgNO_3-N/L$. Nitrate in anaerobic sludge was converted to nitrogen gas(denitrification) or ammonia (ammonification) according to pH of influent, COD removal efficiency was easily affected by the change of volumetric loading rates and nitrate concentration. And when influent pH was about 4.7, most nitrate changed to ammonia while when influent pH was about 6.8~7.0, most nitrate denitrified independent of $COD/NO_3-N$ ratio. Most granules were gray and a few were black. In gray-colored granule, black inner side was covered with gray substance and SEM illustrated Methanoccoci type microorganisms which were compact spherical shape. Anaerobic filter removed residual COD effectively which was left in sludge bed due to the inhibition of nitrogen oxide.

• Journal of the Korean Home Economics Association
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• v.43 no.4 s.206
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• pp.161-172
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• 2005

The present study investigation the effect of a project approach program on children's cognitive styles. It examined closely the characteristics and processes of the project approach program to determine its impact on children's individual cognitive styles such as divergent thinking, field independence, and reflection. The subjects were 384-year-old children. Eighteen children were assigned to the experimental group and twenty to the control group. Pretest-treatment-posttest design was adopted for this study. Collected data were analyzed with SPSS Win 10.0 and processed statistically using average, standard deviation, and ANCOVA. For the children's divergent thinking, the children with the project approach program showed significant difference in fluency and flexibility, but no difference in originality and elaboration, compared to the children in the control group. Children with the project approach program showed more field independence than those in the control group. Children with the project approach program showed no difference in reflection. These results showed that the project approach pro!3ram partly influenced the children's cognitive styles.

• Clinical and Experimental Reproductive Medicine
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• v.41 no.2
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• pp.41-46
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• 2014

IVM refers to the maturation of immature oocytes in culture after their recovery from small antral follicles at the stage prior to selection and dominance. IVM requires little or no FSH in vivo and has been proposed as an alternative to conventional IVF, since it reduces the primary adverse effects caused by controlled ovarian stimulation, including the ovarian hyperstimulation syndrome. Moreover, IVM is a promising option for cases for which no standard protocol is suitable, such as FSH resistance, contraindications for ovarian stimulatory drugs, and the need for urgent fertility preservation. Recently, IVM has been used in women with regular cycles and normal ovaries. However, the pregnancy rate following IVM is suboptimal compared with that of conventional IVF, indicating that further studies to optimize the protocol and the culture conditions are warranted.