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Residue analysis and risk assessment of ethoxyquin and ethoxyquin dimer in farmed fish (양식어류 중 Ethoxyquin과 Ethoxyquin dimer의 잔류분석 및 위해평가)

  • Choi, Young-Hee;Ko, Suk-Kyung;Ryu, Seung-Hee;Jin, Young-Hee;Kwak, Jae-Eun;Lee, Myung-Sook;Kim, Bog-Soon;Hang, In-Sook
    • Korean Journal of Food Science and Technology
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    • v.53 no.3
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    • pp.239-244
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    • 2021
  • In the present study, liquid chromatography tandem-mass spectrometry was used to conduct a risk assessment of ethoxyquin and ethoxyquin dimer residues in 288 farmed fish sold in wholesale and traditional markets in Seoul. The detection range (detection rate) of ethoxyquin and ethoxyquin dimer was 0.005~0.309 mg/kg (4.9%) and 0.001~2.828 mg/kg (69.8%), respectively. Ethoxyquin was detected only in freshwater eels, loaches, catfish, and flatfish, whereas ethoxyquin dimer was present in all fish species. To estimate the dietary exposure levels of ethoxyquin and ethoxyquin dimer, the hazard index, calculated using the acceptable daily intake and estimated daily intake, ranged from 0.001 to 0.300%. Our results indicate that there is no significant exposure risk to humans from these farmed fish despite 10 farmed fish samples exceeding the maximum residue level (1.0 mg/kg as the sum of ethoxyquin and ethoxyquin dimer).

Correlation of animal-based parameters with environment-based parameters in an on-farm welfare assessment of growing pigs

  • Hye Jin, Kang;Sangeun, Bae;Hang, Lee
    • Journal of Animal Science and Technology
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    • v.64 no.3
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    • pp.539-563
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    • 2022
  • Nine pig farms were evaluated for the welfare quality in Korea using animal- and environment-based parameters (particularly air quality parameters) during the winter of 2013. The Welfare Quality® (WQ®) protocol consists of 12 criteria within four principles. The WQ® protocol classifies farms into four categories ranging from 'excellent' to 'not classified'. Each of these criteria has specific measures for calculating scores. Calculations for the welfare scores were conducted online using the calculation model in the WQ® protocol. Environment-based parameters like microclimate (i.e., temperature, relative humidity, air speed, and particulate matter), bacteria (total airborne bacteria, airborne total coliform, and airborne total Escherichia coli), concentration of gases (carbon dioxide, ammonia, and hydrogen sulfide) were measured to investigate the relationship between animal- and environment-based parameters. Correlations between the results of animal- and environment-based parameters were estimated using spearman correlation coefficient. The overall assessments found that five out of nine farms were 'acceptable', and four farms were 'enhanced'; no farm was 'not classified'. The average score for the four principles across the nine farms, in decreasing order, were 'good feeding' (63.13 points) > 'good housing' (59.26 points) > 'good health' (33.47 points) > 'appropriate behaviors' (25.48 points). In the result of the environment aspect, the relative humidity of farms 2 (93.4%), 3 (100%), and 9 (98%) was much higher than the recommended maximum relative humidity of 80%, and four out of the nine farms had ammonia concentrations greater than 40 ppm. Ammonia had negative correlations with 'positive social behaviors' and positive emotional states: content, enjoying, sociable, playful, lively, happy and it had positive correlations with negative emotional states: aimless, distressed. The concentration of carbon dioxide had negative correlations with positive emotional states; calm, sociable, playful, happy and it had a positive correlation with negative emotional state; aimless. Our results indicate that the control of the environment for growing pigs can help improve their welfare, particularly via good air quality (carbon dioxide, ammonia, hydrogen sulfide).

Comparison on the Performance of Soil Improvement in Thick Soft Ground Using Single-Core and Double-Core PBD (단일 및 이중 코어 PBD에 의한 대심도 연약지반 개량 효과에 관한 비교연구)

  • Yang, Jeong-Hun;Hong, Sung-Jin;Kim, Hyung-Sub;Lee, Woo-Jin;Choi, Hang-Seok
    • Journal of the Korean Geotechnical Society
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    • v.25 no.8
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    • pp.33-45
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    • 2009
  • The conventional single-core PBDs have been widely used in order to accelerate consolidation settlement of soft grounds. When using the single-core PBD in a thick clay deposit, a delay of consolidation may occur due to high confining pressure in the thick deposit and necking of drains. This study is to compare the performances of soil improvement by the single-core and double-core PBD installed at a site in Busan New Port which exhibits approximately a 40m-thick clay layer. An in-situ test program was performed at the test site where a set of the double-core PBDs and single-core PBDs were installed to compare the efficiency of each drain. In addition, the discharge capacity of each PBD has been measured using the modified Delft Test. A series of laboratory tests for estimating in-situ soil properties have also been performed in order to obtain input parameters for a numerical program ILLICON. The discharge capacity of the double-core PBD is higher than that of the single-core PBD in the modified Delft Test. However it is observed from the comparative in-situ test and numerical analysis that there is no difference in the performance of ground improvement between the two drain systems. This discrepancy comes from the fact that the amount of water released during consolidation in most common field conditions is much smaller than the capacity of even the single core PBD. And thus, considering actual field conditions, it can be concluded that the single-core PBD has enough discharge capacity even in the thick clay deposit such as this test site.

Distribution of the Seagrass, Zostera spp. in Ulleungdo (울릉도 연안의 거머리말속 잘피 분포)

  • PARK, JUNG-IM;KIM, JAE HOON;SONG, HWI-JUNE;KIM, GU YEON
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.25 no.4
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    • pp.106-116
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    • 2020
  • To examine distribution of the Zostera species growing naturally in Ulleungdo, scuba diving surveys using ships were conducted along the coast and inside the harbors of the island at the end of September 2019. In areas of seagrass occurrence, environmental factors such as nutrient concentrations in water column and sediment pore water, salinity, and sediment organic content were also analyzed. Zostera caulescens meadows appeared in the relatively deep waters (14-24 m MSL) of Cheonbu-ri, Jeodong-ri, Sadong-ri, and Namyang-ri in Ulleungdo, and the total seagrass coverage was approximately 4.9 ha. Approximately 0.9 ha of Zostera marina meadow was found at the depths of 3-5 m MSL within Hyeonpo-hang in Hyeonpo-ri. The average shoot density and biomass of Z. caulescens were 121.9±9.7 shoot m-2 and 99.0±13.2 gDW m-2, respectively, with no significant differences by location. The average shoot density and biomass of Z. marina were 193.8±18.8 shoot m-2 and 102.6±6.8 gDW m-2, respectively. The nutrient concentrations in the sediment pore water and sediment organic content in the seagrass meadows in Ulleungdo were lower than those in eelgrass meadows on the southern and eastern coasts of Korea. These results will provide useful basic information for the marine protected species, Z. caulescens and Z. marina, and for the conservation of the waters of Ulleungdo, which has been designated as a marine protected area.

Extraction of mandibular third molars: relationship of preoperative anxiety with body mass index, serum high-sensitivity C-reactive protein levels, and visual analog scale scores and predictors of postoperative complications

  • Eunjee Lee;Yu-Jin Jee;Jaewoong Jung;Mu Hang Lee;Sung ok Hong
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.5
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    • pp.252-261
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    • 2023
  • Objectives: Patients undergoing oral surgery exhibit high anxiety, which may elevate their cortisol levels and affect postoperative recovery. Overweight patients are often encountered in the dental clinic due to the increasing prevalence of overweight. We aimed to investigate the relationships between preoperatively assessed body mass index (BMI), serum cortisol and high-sensitivity C-reactive protein (hs-CRP) levels, and visual analog scale (VAS) scores and preoperative anxiety in patients undergoing mandibular third molar (MM3) extraction and to identify predictors of postoperative complications. Patients and Methods: We analyzed 43 patients (age, 20-42 years) undergoing MM3 extraction. At the first visit, patients completed the Modified Dental Anxiety Scale (MDAS) and Amsterdam Preoperative Anxiety and Information Scale (APAIS) questionnaires. Their BMI and VAS scores were also calculated. The participants underwent blood tests 1 hour before MM3 extraction. On the first postoperative day, the participants' VAS scores and serum hs-CRP levels were reevaluated. Results: We found that BMI was significantly correlated with preoperative VAS scores. Further, BMI and preoperative hs-CRP levels were significantly correlated among women and patients undergoing extractions of fully impacted MM3s. No correlations were found between serum cortisol and other variables. The preoperative MDAS and VAS scores were significantly positively correlated, especially among patients undergoing extractions of fully impacted MM3s. Multiple linear regression showed that BMI and the eruption status of the MM3 were significant predictors of postoperative hsCRP levels and VAS scores, respectively. Conclusion: In MM3 removals, patients with higher BMI showed elevated hs-CRP and higher VAS scores before surgery. Patients with higher anxiety among those undergoing extractions of fully impacted MM3s showed higher preoperative VAS scores. The two main predictors of postoperative complications were BMI and MM3 eruption status.

Effects of Model Construction and Pattern Identification Activities on Views on the Nature of Science in the Context of Science 10 Inquiry Unit (10학년 과학 탐구 단원의 맥락에서 모델구성과 규칙발견을 통한 명시적 수업이 과학의 본성의 관점에 미치는 효과)

  • Cho, Jung-Il;Kim, Jin-Hee;Hong, Hang-Hwa
    • Journal of The Korean Association For Science Education
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    • v.28 no.8
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    • pp.955-963
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    • 2008
  • This study was conducted to assess any change in students' views on the nature of science (NOS) after lessons through the activities of model construction and pattern identification. The instrument used to examine NOS views was the Views of Nature of Science questionnaire (VNOS). Four students' responses on VNOS before and after instruction were analyzed. The two levels of their views, novice and expert, were judged by the authors based on criteria set by several science educators. The instruction consisted of six hours of the so-called black box and cube activities developed for model construction and pattern identification, respectively. Students' views were at the novice level in definition of scientific theory, tentativeness of scientific knowledge, difference of hypotheses, theories and laws, model construction, and creativity and imagination in experiments and investigations. Students' views on NOS knowledge such as model and theory have improved for two students after instruction. The improvement seemed to be due to an explicit approach using the activities of model construction and pattern identification. The factors of changes and no-changes of views on NOS were identified and discussed in terms of improvement of the views.

Combining Non-Contrast CT Signs With Onset-to-Imaging Time to Predict the Evolution of Intracerebral Hemorrhage

  • Lei Song;Xiaoming Qiu;Cun Zhang;Hang Zhou;Wenmin Guo;Yu Ye;Rujia Wang;Hui Xiong;Ji Zhang;Dongfang Tang;Liwei Zou;Longsheng Wang;Yongqiang Yu;Tingting Guo
    • Korean Journal of Radiology
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    • v.25 no.2
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    • pp.166-178
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    • 2024
  • Objective: This study aimed to determine the predictive performance of non-contrast CT (NCCT) signs for hemorrhagic growth after intracerebral hemorrhage (ICH) when stratified by onset-to-imaging time (OIT). Materials and Methods: 1488 supratentorial ICH within 6 h of onset were consecutively recruited from six centers between January 2018 and August 2022. NCCT signs were classified according to density (hypodensities, swirl sign, black hole sign, blend sign, fluid level, and heterogeneous density) and shape (island sign, satellite sign, and irregular shape) features. Multivariable logistic regression was used to evaluate the association between NCCT signs and three types of hemorrhagic growth: hematoma expansion (HE), intraventricular hemorrhage growth (IVHG), and revised HE (RHE). The performance of the NCCT signs was evaluated using the positive predictive value (PPV) stratified by OIT. Results: Multivariable analysis showed that hypodensities were an independent predictor of HE (adjusted odds ratio [95% confidence interval] of 7.99 [4.87-13.40]), IVHG (3.64 [2.15-6.24]), and RHE (7.90 [4.93-12.90]). Similarly, OIT (for a 1-h increase) was an independent inverse predictor of HE (0.59 [0.52-0.66]), IVHG (0.72 [0.64-0.81]), and RHE (0.61 [0.54-0.67]). Blend and island signs were independently associated with HE and RHE (10.60 [7.36-15.30] and 10.10 [7.10-14.60], respectively, for the blend sign and 2.75 [1.64-4.67] and 2.62 [1.60-4.30], respectively, for the island sign). Hypodensities demonstrated low PPVs of 0.41 (110/269) or lower for IVHG when stratified by OIT. When OIT was ≤ 2 h, the PPVs of hypodensities, blend sign, and island sign for RHE were 0.80 (215/269), 0.90 (142/157), and 0.83 (103/124), respectively. Conclusion: Hypodensities, blend sign, and island sign were the best NCCT predictors of RHE when OIT was ≤ 2 h. NCCT signs may assist in earlier recognition of the risk of hemorrhagic growth and guide early intervention to prevent neurological deterioration resulting from hemorrhagic growth.

Thrombocytopenia after Aortic Valve Replacement Using Sutureless Valves

  • Mil Hoo Kim;Soojin Lee;Juhyun Lee;Seohee Joo;You Kyeong Park;Kang Min Kim;Joon Chul Jung;Hyoung Woo Chang;Jae Hang Lee;Dong Jung Kim;Jun Sung Kim;Kay-Hyun Park;Cheong Lim
    • Journal of Chest Surgery
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    • v.57 no.4
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    • pp.371-379
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    • 2024
  • Background: Sutureless valves are widely used in aortic valve replacement surgery, with Perceval valves and Intuity valves being particularly prominent. However, concerns have been raised about postoperative thrombocytopenia with Perceval valves (Corcym, UK). We conducted a comparative analysis with the Intuity valve (Edwards Lifesciences, USA), and assessed how thrombocytopenia affected patient and transfusion outcomes. Methods: Among 595 patients who underwent aortic valve replacement from June 2016 to March 2023, sutureless valves were used in 53 (Perceval: n=23; Intuity: n=30). Platelet counts were monitored during hospitalization and outpatient visits. Daily platelet count changes were compared between groups, and the results from patients who underwent procedures using Carpentier Edwards Perimount Magna valves were used as a reference group. Results: Compared to the Intuity group, the Perceval group showed a significantly higher amount of platelet transfusion (5.48±1.64 packs vs. 0.60±0.44 packs, p=0.008). During the postoperative period, severe thrombocytopenia (<50,000/μL) was significantly more prevalent in the Perceval group (56.5%, n=13) than in the Intuity group (6.7%, n=2). After initial postoperative depletion, daily platelet counts increased, with significant differences observed in the extent of improvement between the Perceval and Intuity groups (p<0.001). However, there was no significant difference in early mortality or the incidence of neurological complications between the 2 groups. Conclusion: The severity of postoperative thrombocytopenia differed significantly between the Perceval and Intuity valves. The Perceval group showed a significantly higher prevalence of severe thrombocytopenia and higher platelet transfusion volumes. However, thrombocytopenia gradually recovered during the postoperative period in both groups, and the early outcomes were similar in both groups.

Premenstrual Syndrome and its Relationship with Previous Abuse History and Dissociative Symptoms (월경전기 증후군과 해리증상 및 과거 학대 경험과의 연관성)

  • Kim, Jong-In;Choi, Tae-Kyou;Yoon, Jae-Hang;Suh, Shin-Young
    • Korean Journal of Psychosomatic Medicine
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    • v.16 no.2
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    • pp.112-119
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    • 2008
  • Objectives : Premenstrual syndrome(PMS) is known to occur in more than 80% of reproductive women. Since PMS is closely related to changes in sex hormones, biological factors are suspected to be associated with the syndrome, but there have been no consistent reports regarding biological causes. In that sense, it is postulated that the occurrence of PMS is much dependent on the biological aspects, but that the severity or characteristics of the syndrome is more dependent on the psychological factors. Studies focusing on psychological factors are based on the theory that symptoms of PMS and previous psychologically traumatic events are closely related. If the theory is valid, it can be further postulated that symptom severity of PMS is associated with dissociative symptoms, since traumatic events are known to be related to dissociative symptoms. In this study, we tried to find out the association of PMS symptom severity with previous abuse history and dissociative symptoms. Methods : Subjects for the study were 377 nurses working in Seoul, Kyung-gi, and Kyung-book. 183 subjects who submitted valid data entered the study. The presence and the symptom severity of PMS were rated using Daily Records of Severity of Problems(DRSP) and Shortened Premenstrual Assessment Form(SPAF). Dissociative symptoms were evaluated with Dissociation Experience Scale Korean version(DES-K). Previous physical/verbal abuse, sexual abuse, and parental spouse abuse experience were rated with correspondent abuse scales. Results : Subjects were divided into 3 groups as No PMS group, mild to moderate PMS group, and severe PMS group according to SPAF total score. There was a statistically significant difference in DES-K total score among 3 groups($x^2=14.966$, df=2, p=0.001). Physical/verbal abuse scale($x^2=14.397$, df=2, p=0.001), sexual abuse scale($x^2=8.376$, df=2, p=0.015), and parental spouse abuse scale($x^2=9.322$, df=2, p=0.009) also revealed a significant difference among 3 groups. Symptom severity of PMS using SPAF total score showed a positive correlation both with degree of dissociative experience and previous abuse experience. There was a statistically significant difference in both dissociative experience and previous abuse experience among 3 groups. Conclusion : These results show that there can be a possible association among PMS symptoms, dissociative symptoms, and previous psychologically traumatic experience.

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Canopy-Related Characteristics of Korean Soybean Cultivars (한국 콩 품종의 초형관련 형질의 특성)

  • Kim, Hong-Sig;Lee, Ku-Hwan;Song, Hang-Lin;Kim, Seong-Jin;Hur, Gun;Woo, Sun-Hee;Jong, Seung-Keun
    • Korean Journal of Breeding Science
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    • v.40 no.2
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    • pp.143-152
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    • 2008
  • This study was conducted to obtain basic information on mainstem, branch and leaf characteristics related to canopy for development of high yielding cultivar using 70 Korean soybean cultivars developed from 1913 to 2000. Variations of canopy width, branch length, and canopy width/length ratio were higher compared to other characteristics among 12 mainstem and branch characters. Variations of petiole angle, leaflet width/length ratio and compound leaf dry weight were higher than other characteristics among eight leaf characters related to plant canopy. Three classifications of soybean cultivars were used based on usage: I)soy sauce and tofu, II)bean sprout, and III)cooking with rice. Canopy width/length ratio was higher in group III, cooking with rice than group I, soy sauce and tofu, and group II, bean sprout, and there was no difference between the two, group I and group II. The total branch length/main stem height ratio was higher in group II, bean sprout and group III, cooking with rice than group I, soy sauce and tofu. Mainstem and branch characteristics related to plant canopy were classified into four groups by ratio of canopy width/length and total branch length/main stem length, respectively. Soybean cultivars with narrow canopy and high dependence of mainstem were Danweonkong, Keumkangkong, Shelby, and Shinpaldalkong. Soybean cultivars with broad canopy and high dependence of mainstem were Kanglim, Keumkangdaelip, and Jinyulkong, and a cultivar with broad canopy and high dependence of branch were Geomjeongkong 2. Leaflet length/width ratio was lowest in cooking with rice and there was no difference between soy sauce and tofu and bean sprout. Compound leaf area was largest in cooking with rice and smallest in bean sprout. Leaf petiole length was short in bean sprout and there was no difference between soy sauce and tofu and bean sprout. Leaf petiole angle was highest in cooking with rice and lowest in bean sprout. Leaf type was classified into four groups based on leaflet width/length ratio and compound leaf area, respectivly. Buseok and Taekwangkong had an oval leaflet and largest area of compound leaf. Eunhakong and Sohokong had extreme narrow leaflet and smallest area of compound leaf. Leaf petiole type was classified into three and four groups based on leaf petiole length and angle, respectively. A soybean cultivar with the shortest petiole length and smallest petiole angle was Eunhakong and cultivars with short petiole length and large petiole angle were Alchankong, Muhankong, and Pureunkong. A soybean cultivar with long petiole length and small petiole angle was Sinpaldalkong 2. Among a total of 70 Korean soybean cultivars, Eunhakong had an extreme narrow type in leaf, smallest compound leaf area, shortest petiole length, and smallest petiole angle of compound leaf.