• Journal of Dental Rehabilitation and Applied Science
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• v.23 no.4
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• pp.303-312
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• 2007

Recently several studies have been developed not only to apply bone materials to bony defect, but also to use osteogenic and osteoinductive materials to form bone more effectively. In 1998 Mark et al applied gel formation of PRP(platelet-rich plasma) in bony transplantation for mandibular reconstruction as one of the method of stimulating bone formation in maxillofacial area, which is contain of varies growth factors. After he reported that PRP accelerate bone formation, which is used in varies bone transplantation and augmentation with a good result. Especially there are amount of growth factors in PRP, and PRP increase angiogenesis, cell division, and mesenchymal cell growth. Moreover it is capable of osteoconduction, hemostatitis, anti-infection, forming the shape at transplantation, ease of handling, and recipient site stability. So it is known that success rate is high in bone transplantation. However PRP need tissue adhesive to make plasma to solid form. Thrombin and calcium chloride, component of PRP, is extracted from autogenic donor. So it is expensive to extract and there is possibility of hepatitis, AIDS, and hematogenous metastasis. After all, tissue adhesive have the limitation and danger of use. So we are willing to introduce that we had get some idea after using PRF(platelet-rich fibrin) in the various hard and soft tissue bony defect, which is self extracted simply and contain growth factors.

• Journal of Pharmaceutical Investigation
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• v.34 no.3
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• pp.229-254
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• 2004

The objective of this study was to scrutinize the rationale of SUPAC-MR and its application in processing postapproval changes to modified release solid oral dosage forms. The types of postapproval changes that were primarily covered with SUPAC-MR included variations in the components and composition, the site of manufacturing, batch size, manufacturing equipment, and manufacturing process. SUPAC-MR defined levels of postapproval changes that the industry might make. Classification of such categories was based on the likelihood of risk occurrence and potential impact of changes upon the safety and efficacy of approved drug products. In most cases, the changes could be classified into 3 levels. It described what chemistry, manufacturing, and control tests should be conducted for each change level. The important tests specified in SUPAC-MR were batch release, stability, in vitro dissolution, and in vivo bioequivalence tests. It then suggested what type of a filing report should be submitted to the FDA for each change level. In general, level 1 changes could be reported in an annual report, whereas level 2 and/or 3 changes could be submitted in changes-being-effected or prior approval supplements. It could be understood that the purpose of SUPAC-MR was to maintain the safety and quality of approved modified release solid oral dosage forms undergoing certain changes. At the same time, it contributed to providing a less burdensome regulatory process with the manufacturers when they wanted to make postapproval changes. European regulatory agencies also implemented SUPAC-like regulations in handling such changes to drug products. Therefore, in this study a recommendation was made for KFDA and the Korean industry to evaluate thoroughly the usefulness of these guidances and regulations in dealing with postapproval changes to modified release solid oral dosage forms.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.5
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• pp.183-188
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• 2013

A variety of cluster analysis techniques prerequisite to cluster objects having similar characteristics in data mining. But the clustering of those algorithms have lots of difficulties in dealing with categorical data within the databases. The imprecise handling of uncertainty within categorical data in the clustering process stems from the only algebraic logic of rough set, resulting in the degradation of stability and effectiveness. This paper proposes a information-theoretic rough entropy(RE) by taking into account the dependency of attributes and proposes a technique called min-mean-mean roughness(MMMR) for selecting clustering attribute. We analyze and compare the performance of the proposed technique with K-means, fuzzy techniques and other standard deviation roughness methods based on ZOO dataset. The results verify the better performance of the proposed approach.

• Industrial Engineering and Management Systems
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• v.4 no.1
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• pp.47-53
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• 2005

The efficiency of fabrication (fab) operation is one of the key factors in order for a semiconductor manufacturing company to stay competitive. Optimization of manpower and forecasting manpower needs in a modern fab is an essential part of the future strategic planing and a very important to the operational efficiency. As the semiconductor manufacturing technology has entered the 8-inch wafer era, the complexity of fab operation increases with the increase of wafer size. The wafer handling method has evolved from manual mode in 6-inch wafer fab to semi-automated or fully automated factory in 8-inch and 12-inch wafer fab. The distribution of manpower requirement in each specialty varied as the trend of fab operation goes for downsizing manpower with automation and outsourcing maintenance work. This paper is to study the specialty distribution of manpower from the requirement in a typical 6-inch, 8-inch to 12-inch wafer fab. The human resource planning in today’s fab operation shall consider many factors, which include the stability of technical talents. This empirical study mainly focuses on the human resource planning, the manpower distribution of specialty structure and the forecast model of internal demand/supply in current semiconductor manufacturing company. Considering the market fluctuation with the demand of varied products and the advance in process technology, the study is to design a headcount forecast model based on current manpower planning for direct labour (DL) and indirect labour (IDL) in Taiwan’s fab. The model can be used to forecast the future manpower requirement on each specialty for the strategic planning of human resource to serve the development of the industry.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.07a
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• pp.292-295
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• 2004

The SIT was introduced by Nishizawa. in 1972. When compared with high-voltage, power bipolar junction transistors, SITs have several advantages as power switching devices. They have a higher input impedance than do bipolar transistors and a negative temperature coefficient for the drain current that prevents thermal runaway, thus allowing the coupling of many devices in parallel to increase the current handling capability. Furthermore, the SIT is majority carrier device with a higher inherent switching speed because of the absence of minority carrier recombination, which limits the speed of bipolar transistors. This also eliminates the stringent lifetime control requirements that are essential during the fabrication of high-speed bipolar transistors. This results in a much larger safe operating area(SOA) in comparison to bipolar transistors. In this paper, vertical SIT structures are proposed to improve their electrical characteristics including the blocking voltage. Besides, the two dimensional numerical simulations were carried out using ISE-TCAD to verify the validity of the device and examine the electrical characteristics. A trench gate region oxide power SIT device is proposed to improve forward blocking characteristics. The proposed devices have superior electrical characteristics when compared to conventional device. Consequently, the fabrication of trench oxide power SIT with superior stability and electrical characteristics is simplified.

• Journal of KIISE:Computing Practices and Letters
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• v.11 no.5
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• pp.458-463
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• 2005

The total asset management system is used for banks or financial institutions for the management of trusteed assets or own assets and it is divided into three systems: the front-office system, the middle-office system and the back-office system by its business areas and functionalities. This kind of asset management system is a huge and complex system handling large data and various financial products, and requires professional knowledges like accounting, financial product specific knowledge, compliance and regulations, etc. It also performs high level computation for NAV calculation and risk measurement on every day Therefore, it needs absolute stability, extendability and efficiency and should handle the frequent change of regulation and products and connectivity with outdoor institutions. In this paper, we report our successful development of such a system and discuss issues regarding its efficient system design and system construction.

• Journal of the Korean Society of Propulsion Engineers
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• v.15 no.3
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• pp.47-57
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• 2011

All solid rocket propellants are divided in two basic classes according to chemical state: homogeneous(double base) and heterogeneous (composite). Today, composite propellants are extensively used as power sources covering the range from gas generators and small rocket systems to large launch vehicles in space programs. The development of composite rocket propellants in the past was mainly directed to thermoset polymers. But, the thermoset composite propellants have the complication in formulation and fabricating process to adapt to rocket system requirements. In contrast to the thermoset propellant, the PVC plastisols composite propellants have the advantages in the view of loss in manufacturing process, low cost of raw material, and stability of the handling process even though moderate ballistic and mechanical properties. It is predicted that the application field of this class will be used more widely than any other classes.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.7
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• pp.2257-2285
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• 2022

Cyber-physical systems (CPS) have been growing exponentially due to improved cloud-datacenter infrastructure-as-a-service (CDIaaS). Incremental expandability (scalability), Quality of Service (QoS) performance, and reliability are currently the automation focus on healthy Tier 4 CDIaaS. However, stable QoS is yet to be fully addressed in Cyber-physical data centers (CP-DCS). Also, balanced agility and flexibility for the application workloads need urgent attention. There is a need for a resilient and fault-tolerance scheme in terms of CPS routing service including Pod cluster reliability analytics that meets QoS requirements. Motivated by these concerns, our contributions are fourfold. First, a Distributed Non-Recursive Cloud Model (DNRCM) is proposed to support cyber-physical workloads for remote lab activities. Second, an efficient QoS stability model with Routh-Hurwitz criteria is established. Third, an evaluation of the CDIaaS DCN topology is validated for handling large-scale, traffic workloads. Network Function Virtualization (NFV) with Floodlight SDN controllers was adopted for the implementation of DNRCM with embedded rule-base in Open vSwitch engines. Fourth, QoS evaluation is carried out experimentally. Considering the non-recursive queuing delays with SDN isolation (logical), a lower queuing delay (19.65%) is observed. Without logical isolation, the average queuing delay is 80.34%. Without logical resource isolation, the fault tolerance yields 33.55%, while with logical isolation, it yields 66.44%. In terms of throughput, DNRCM, recursive BCube, and DCell offered 38.30%, 36.37%, and 25.53% respectively. Similarly, the DNRCM had an improved incremental scalability profile of 40.00%, while BCube and Recursive DCell had 33.33%, and 26.67% respectively. In terms of service availability, the DNRCM offered 52.10% compared with recursive BCube and DCell which yielded 34.72% and 13.18% respectively. The average delays obtained for DNRCM, recursive BCube, and DCell are 32.81%, 33.44%, and 33.75% respectively. Finally, workload utilization for DNRCM, recursive BCube, and DCell yielded 50.28%, 27.93%, and 21.79% respectively.

• Journal of the Korea Society for Simulation
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• v.19 no.4
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• pp.99-109
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• 2010

Existing research about automated wafer transport management strategy for semiconductor manufacturing equipment was mainly focused on dispatching rules which is optimized to specific system layout, process environment or transfer patterns. But these methods can cause problem as like requiring additional rules or changing whole transport management strategy when applied to new type of process or system. In addition, a lack of consideration for interconnectedness of the added rules can cause unexpected deadlock. In this study, in order to improve these problems, propose dynamic priority based transfer job decision making algorithm which is applicable with regardless of system lay out and transfer patterns. Also, extra rule handling part proposed to support special transfer requirement which is available without damage to generality for maintaining a consistent scheduling policies and minimize loss of stability due to expansion and lead to improve productivity at the same time. Simulation environment of Twin-slot type semiconductor equipment was built In order to measure performance and examine validity about proposed wafer scheduling algorithm.

• Nuclear Engineering and Technology
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• v.55 no.4
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• pp.1485-1494
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• 2023

The bow of the nuclear fuel assembly is a well-known phenomenon. One of the vital criteria during the history of nuclear fuel development has been fuel assembly's mechanical stability. Once present, the fuel assembly bow can lead to safety issues like excessive water gap and power redistribution or even incomplete rod insertion (IRI). The extensive bow can result in assembly handling and loading problems. This is why the fuel assembly's bow is one of the most often controlled geometrical factors during periodic fuel inspections for VVER when compared e.g. to on-site fuel rod gap measurements or other instrumental measurements performed on-site. Our proposed screening method uses existing video records for fuel inspection. We establish video frames normalization and aggregation for the purposes of bow measurement. The whole process is done by digital image processing algorithms which analyze rotations of video frames, extract angles whose source is the fuel set torsion, and reconstruct torsion schema. This approach provides results comparable to the commonly utilized method. We tested this new approach in real operation on 19 fuel assemblies with different campaign numbers and designs, where the average deviation from other methods was less than 2 % on average. Due to the fact, that the method has not yet been validated during full scale measurements of the fuel inspection, the preliminary results stand for that we recommend this method as a complementary part of standard bow measurement procedures to increase measurement robustness, lower time consumption and preserve or increase accuracy. After completed validation it is expected that the proposed method allows standalone fuel assembly bow measurements.