• Title/Summary/Keyword: Hair removal

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Depilatory creams increase the number of hair follicles, and dermal fibroblasts expressing interleukin-6, tumor necrosis factor-α, and tumor necrosis factor-β in mouse skin

  • Tsai, Pi-Fen;Chou, Fen-Pi;Yu, Ting-Shuan;Lee, Huei-Jane;Chiu, Chun-Tang
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.6
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    • pp.497-506
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    • 2021
  • Besides using for hair removal, depilatory agents have been considered to be used as a penetration enhancer for transepidermal drug delivery. To examine the effect in hair follicles (HFs), two commercially available depilatory creams were tested on the dorsal skin of mice to monitor the effect deep into the skin structure. Fifteen male BALB/c mice were used in this study. Depilatory creams were applied to the dorsal skin of the same animal using shaved and untouched treatments as controls to minimize individual differences. Skin samples were collected at three days, one week and two weeks (n = 5 for each) after the treatment, and subjected for hematoxylin-eosin staining, and immunohistochemical analysis for proinflammatory cytokines. The morphological examination showed an increase in the thickness of epidermal layer of the depilatory cream-treated skin at early time points and in the subcutis at two weeks. Depilatory cream promoted entry of anagen phase and increased the number of hair follicles in the subcutis at one and two weeks. Immunohistochemistry showed elevated percentages of dermal fibroblasts expressing interleukin-6, tumor necrosis factor-α, and tumor necrosis factor-β. Shaving process increased the thickness of epidermis and dermis as depilatory creams did, but did neither induce the expression of proinflammatory cytokines in the dermal fibroblasts nor the number of HFs. The results suggested that the commercially available depilatory creams caused a transient minor inflammatory response of the skin and increased the levels of cytokines that might subsequently affect hair growth.

A population-based study of breast implant illness

  • Magno-Padron, David A.;Luo, Jessica;Jessop, Terry C.;Garlick, Jared W.;Manum, Joanna S.;Carter, Gentry C.;Agarwal, Jayant P.;Kwok, Alvin C.
    • Archives of Plastic Surgery
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    • v.48 no.4
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    • pp.353-360
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    • 2021
  • Background Despite evidence supporting the safety of breast implants, some women associate their implants with adverse health effects and have called this syndrome "breast implant illness." We sought to characterize breast implant illness symptoms and to report how implant removal affects their symptoms. Methods An anonymous 20 question survey was administered to the Facebook group: "UTAH Breast Implant Illness" to characterize the symptoms these women attributed to their breast implants. Several questions allowed us to evaluate how implant removal affected women's symptoms. Results Of the 182 respondents, 97% report that implants negatively affect their health and 95% identify these symptoms with breast implant illness. Ninety-six percent of respondents had implants placed for cosmetic reasons and 51% had silicone implants. The most common symptoms associated with breast implant illness are brain fog (95%), fatigue (92%), joint pain (80%), and hair loss (74%). Sixty percent of respondents learned about breast implant illness from family/friends and/or social media platforms (56%), 40% of respondents had their implants removed, and 97% report relief of their symptoms post-removal (23% complete, 74% partial). Following explantation, there was a significant improvement in all but one reported symptom. An association was found between the number of symptoms reported prior to explantation and the number of symptoms resolving following explantation. Conclusions Breast implant illness is a syndrome characterized by fatigue, decreased focus, hair loss, and joint pain after the placement of breast implants. Nearly all patients report improvement of symptoms after implant removal. Significant efforts should be made to better understand breast implant illness and its etiology.

Experimental Studies on the Hair Growth Activity of Drynariae Rhizoma Extracts in C57BL/6N Mice (C57BL/6N 생쥐에서 골쇄보(骨碎補) 추출물을 이용한 발모(發毛)효과에 대한 실험적 연구)

  • Jung, Suk-Young;Jung, Il-Kook;Kim, Dae-Keun;Jo, Han-Young;Jung, Han-Sol;Lee, Chang-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.2
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    • pp.453-461
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    • 2007
  • Drynariae Rhizoma has been used for promotes mending of the sinews and bone, tonifies the kidney for such symptoms as weak low back and knees, and stimulates the growth of hair as a tinctute for alopecia in oriental medicine. This experiment examined the effect of an acetone extracts of Drynariae Rhizomas(GSB-1), its EtoAc fraction(GB-2) and n-buOH fraction(GSB-3), on hair growth activity of the C57BL/6L mice after topical application to skin. First, We examined on hair growth activity of extracts of Drynariae Rhizomas compare to control and 1 % minoxidil groups. Second, We investigated on the number of hair follicle and mast cells after topical application of extracts of the Drynariae Rhizomas to skin for 16 day. Third, We investigated immunoreactive density of vascular endothelial growth factor(VEGF), protein kinase C-${\alpha}$(PKC-${\alpha}$) and stem(mast) cell factor(SCF) in skin of C57BL/6N mice by immunohistochemical methods. The results were as follows : Hair growth effect of acetone extracts of Drynariae Rhizomas, its EtoAc fraction and n-BuOH fraction was observed in 98 %, 96 % and 60 % in hair removed skin area in 16 day respectively, Immunoreactive density of VEGF in skin of GSB-1 group was weakly stained compare to control group in 10 day, But GSB-2 and GSB-3 groups were mildy stained in bulge and root sheath of skin. Immunolocalization of SCF antigens was observed weakly stained density in epidermis, bulge, stem cells and dermal papilla of control gruop. but in experimental group, immunoreactivity of SCF antigens was observed mildly stained density in bulge, epidermis and root sheath of GSB-1 gruop, heavily stained density in epidermis, bulge and root sheath of GSB-2 and GSB-3 groups to the hair removal skin of C57BL/6N mice on day 10. These experiment suggest that acetone extracts of Drynariae Rhizomas and its EtoAc fraction may be used for topical treatment of alopecia areata.

Development portable hair removal applies PET ($Pause^{10-90}$ and $Energy^{20-40}$ $Trigger^{1-7}$) function

  • Kim, Whi-Young
    • Journal of information and communication convergence engineering
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    • v.7 no.2
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    • pp.223-230
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    • 2009
  • For pulse trigger way and the energy injection rate according to PET ($Pause^{10-90}$ $Energy^{20-40}$ $Trigger^{1-7}$) function, indeed, human body condition, period of dormancy in this research about this back correctly adjustment possible and designed harmless micro carrying along style hair exclusion so that can design and manufacture and run special quality examination and Xenon flash lamp to crawl in human body. Because creating individual's skin model to do stable treatment by light transmission way by skin impedance and measure, must embody treatment special quality of most suitable that draw skin color, energy, wave length, approximately, transmission time, pulse delay etc. and want. Specially, saved standard of war treatment pulse modeling by skin impedance, and manufacture pulse modeling system of most suitable by skin subordinate, and embody suitable treatment pulse. Specially, embody as could do root of a hair exclusion being emitted in pulse form using multi wave length of 560nm, 590nm, 640nm, 755nm and embodied clinical data. If become research repletion furthermore little more, is seen that can approximate in commercialization.

Two Cases Report of Verruca Plana That Developed after Laser Hair Removal (레이저 제모술 후 발생한 편평사마귀 치험 2례)

  • Lee, Kyoung-Yeob;Lee, Eun;Cho, Nae-Kyoung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.28 no.2
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    • pp.112-120
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    • 2015
  • Purpose : To observe effects of TKM (Traditional Korean Medicine) treatment for 2 patients who had verruca plana after having laser epilation of leg hair. Methods : We did retrospective chart review for 2 verucca plana patients who had been treated by TKM. TKM treatment included herbal treatment, herbal acupuncture and herbal ointment. Results : After TKM treatment, the patients' verucca plana remarkably disappeared and there was no recurrence. Conclusion : This study suggest that TKM may be an effective treatment for verucca plana.

Morphological Change of Men's Hair Shaft by Weathering (풍화작용에 의한 정상모발의 형태학적 변화)

  • Hong, Wan-Sung;Chang, Byung-Soo;Lim, Do-Seon;Park, Sang-Ock;Yoe, Sung-Moon
    • Applied Microscopy
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    • v.30 no.1
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    • pp.11-20
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    • 2000
  • The morphological changes in normal and weathering hair shafts of the human scalp were investigated by using the transmission and scanning electron microscopes. The hair shaft composed of cuticular layer, cortex and medula. The surface of normal hairs are smooth and covered by imbricated cuticular scales. The cuticular layer consists of five to seven cuticle cells. These cells, which are flat and thin, measuring about $100{\mu}m$ long and $0.4{\mu}m$ thick, appears intercellular membrane complex in diameter 25 nm. The cortex composed of melanin granules and cornified cells, which multicomponent concentric microfibrils in diameter about 8 nm give rise to macrofibrils in diameter $0.5{\mu}m$ to $0.8{\mu}m$ encased in limiting membrane. The melanin granules are spherical shaped about $0.5{\mu}m$ in size and scattered between macrofibrils. The medulla in the normal hairs are $16{\mu}m$ in diameter centrally region of cortex. Normal hair shafts undergo progressive degenerative changes due to a variety of environmental insults. In the initial weathering process of hair, the cuticular scales became irregularly raised and broken, and then cuticle cells formed cytoplasmic vacuolation, following dissociated intercellular membrane complex, ultimately entirely lost and nuded cortex. Occasionally, transverse fissures were seen at hair shafts indicating that the hairs were deteriorated. Complete removal of the cuticular layer in the heavily damaged cortex portions appeared splitting of the cortical cell into its macrofibrils and scattering of melanin granules.

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[Retracted]Gas Mask Removal Efficiency of CO, HCl, HCN, and SO2 Gas Produced by Fire ([논문철회]화재용 방독면의 CO, HCl, HCN, SO2 연소생성물 제거효율)

  • Kong, Ha-Sung;Gong, Ye-Som;Kim, Sang-Heon
    • Fire Science and Engineering
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    • v.29 no.4
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    • pp.57-60
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    • 2015
  • The removal efficiencies by elastic fire gas mask of toxic gases CO, HCl, HCN, and $SO_2$ produced by a fire have a key role in saving lives. The elastic fire gas mask comprises a visible window, elastic hood, gas purification canister, and air vent. It does not have hair or neck thongs, which makes it easy to use and put on quickly. This research examined the removal efficiency of toxic gases by such a mask. The removal efficiencies for CO with a background concentration of 2505.0 ppm were 99.99 and 99.98% after 3.5 and 8.5 min, respectively. The residual CO concentration was drastically increased after 8.5 min. The removal efficiencies for HCl, HCN, and $SO_2$ with background concentrations of 1003.0, 399.0, and 100.3 ppm, respectively, were 100% after 20 min.

Nasopharyngeal Polyp in a Domestic Short Hair Cat (단모종 집고양이의 코인두 폴립 증례)

  • Lee, Da-Mi;Yu, Do-Hyeon;Nho, Dong-Ho;Song, Ru-Hui;Kim, Jun-Hwan;Cho, Ho-Seong;Park, Jin-Ho;Park, Chul
    • Journal of Veterinary Clinics
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    • v.28 no.4
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    • pp.435-437
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    • 2011
  • A 2-year-old, domestic short hair cat presented because of a 2-year history of chronic nasal discharge and chronic otitis. Examination of the oral cavity revealed a mass in the nasopharynx. For further examination, computed tomography (CT) was performed and large polyp was revealed on the nasopharyngeal area. Traction removal of the polyp was performed using a spay hook. After removal of the mass, Horner's syndrome was developed but resolved spontaneously within 14 days.

A Conservation Treatment for the Seated Iron Buddha Statue of Dopian Temple, Cheolwon (철원 도피안사 철조비로자나불상의 보존처리)

  • Hong, Jong-Ouk;Hwang, Jin-Ju;Choi, Joon-Hyun;Shin, Hee-Nai;Lee, Yo-Han;Han, Byung-Il;Le, Oh-Hee
    • 보존과학연구
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    • s.30
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    • pp.171-187
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    • 2009
  • The Seated iron Vairocana Buddha statue of Dopiansa Temple, Cheolwon was designated National treasure No. 63, it is very important to rearch about Korean Buddha statue because it has an inscription on the back indicates that it was made in 865 A.D., the fifth year of the reign of King Gyeongmun(861-875) of Unified Silla(668-935), through the devoted faith of some 1,500 Buddhist followers of the Cheorwon-gun area. In this conservation treatment, for the Seated iron Vairocana Buddha statue of Dopiansa Temple, Cheolwon plating layer and cashew paint layer of the iron pedestal were removed and for the paint the Body of the Buddha, fake metal layer and plaster layer were removed, stabilizing treatment and coating treatment were done, and removal and restoration of earlobe which had been damaged and later was restored with plaster in the regilding in 1988, and the white hair on forehead was replaced with material of rock crystal, and conch-shaped hair damaged was restored on 35 spots.

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