• Journal of Haehwa Medicine
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• v.18 no.2
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• pp.95-104
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• 2009

This study was carried out through the investigation of Oriental and Western medical literature and we was discovered these conclusions about the etiology, treatment, prescription of habitual abortion. The result of this study were as follows : 1. The habitual abortion does agree with 'Hwaltae(滑胎)' and means that spontaneous abortion repeats three times or more. 2. The etiology of habitual abortion is divided 'Deficiency of kidney'(腎虛), 'Deficiency of vital energy and blood'(氣血虛弱), 'Deficiency of yin'(陰虛), 'Clotted blood'(瘀血). 3. By means of cause, the treatment of habitual abortion was mainly made use of 'Tonifying kidney and promoting spleen'(補腎健脾), 'Invigorating vital energy and nourishing blood'(補氣補血), 'Supplementing yin fluid and alleviating fever'(滋陰淸熱), 'Resuscitating blood and removing clotted blood'(活血祛瘀). 4. By means of cause, the prescription of habitual abortion was frequent made use of Bosingochunghwan(補腎固沖丸), Bosingotae$\breve{u}$m(補腎固胎飮), Taesanbans$\breve{o}$ksan(泰山磐石散), $Ch\breve{o}ng\breve{u}mboinghwan$(千金保孕丸), Agyotang(阿膠湯), Gungguibojungtang(芎歸補中湯), Taewon$\breve{u}$m(胎元飮), Gotaej$\breve{o}$n(固胎煎), Baekchulj$\breve{o}$n(白朮煎), Sas$\breve{o}$ngsan(四聖散), Gyegibokryonghwan(桂枝茯苓丸), $Dangguich\breve{o}ng\breve{u}mtang$(當歸千金湯). 5. The Western medical etiology of habitual abortion(recurrent spontaneous early pregnancy loss) is divided Genetic factor(Chromosome aberration), Anatomical deformity, Endocrinologic disorder, Infection, Immunologic factor, Unknown factor(Others).

• The Korea Journal of Herbology
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• v.33 no.4
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• pp.87-93
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• 2018

Objectives : The prevalence of infertility is reported to be 23.3%, which is a serious social problem. Habitual abortion is one of the important complications during pregnancy. The purpose of this study is to help the treatment of habitual abortion by observing and reporting the process in which four women who did not have children due to habitual abortion make healthy birth through treatment. Methods : We administered Jokyungjongok-tang gamibang as a herbal medicine treatment method and treated with acupuncture, moxibustion and uterine steam treatment. Treatment was done once or twice a week but it was also varied depending on the patient's circumstances. The herbal medicines were taken 30 minutes after meals and 3 times a day. While taking the Korean medicine, they were prohibited from eating flour, pork, liquor, tobacco and coffee. Patient status was assessed by consultation through pulse, tongue and abdomen. A detailed questionnaire was performed for each treatment. In some cases, they have tested hormone levels at the hospitals to know ovulation dates. The diagnosis of pregnancy was confirmed by ultrasonography at hospitals and the treatment for habitual abortion was judged based on healthy birth. Results : As a result of herbal medicine, acupuncture, moxibustion and uterine steam treatment, the coldness of the body became weak, the fatigue decreased and the digestive condition gradually began to improve. The bad condition of the uterus caused by the repeated administration of heritage has been improved with Boheosaenghwa-tang gamibang. After administration of Jokyungjongok-tang gamibang, they became pregnant and overcame the condition of addictive abortion and gave birth to healthy children. Conclusion : Jokyungjongok-tang gamibang is effective in overcoming the symptoms of habitual abortion and giving birth to a healthy child for a woman who had no children due to her habitual abortion

• The Journal of Korean Medicine
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• v.16 no.2 s.30
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• pp.115-133
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• 1995

In the Oriental Western Consideration of Habitual Abortion, the result of this study is summarized as follows: 1. Habitual abortion means repetition of Tatae(abortion within 3 months), Sosan(abortion after 3 months), and Bansan(abortion after 5 months), as it agrees with Hoaltae, Sutatae and Nuing-Nuta in oriental medical science. 2. Frequency in Occurrence of habitual abortion is about 0.2-0.4%> in the whole pregnancy and the Ratio of Risk increases according to frequency and age increase. 3. Generally, the cause of habitual abortion is due to the cause of the mother. Therefore, diagnosis and treatment of before-childbirth are needed, and 'measures taken to prevent abortion' is in use to improve the condition of health of before-childbirth in oriental medical science. 4. The 50-60% of early abortion is due to the heterochromosome and the ratio of risk of habirual abortion is hightest in heterochromosome. 5. The causes of habitual abortion are summarized as vital energe and blood weakness. impairment of Chong and Ren, aflection by exopathogen, fever caused by blood deficiency. weakness of the spleen and the stomach, excess of seven emotion. excess of a sexual desire and injury of a contusion and also the treatments are summarized as invigorating qi (vital energy) and enriching the blood, reducing fever and enriching the blood, reinforcing the spleen, tonifying the Chong and Ren, the practice of a sceticism, psychological peace in oriental medical science. 6. The approch of modem oriental medical science is based on diagnosis and treatment based on 'over all analysis of symptoms and signs' of traditional oriental medical science. it goes abreast with diagnosis of western medical science, and it can be expected mare inclusive effect of treatment because 'Acupuncture for prevent abortion', 'Acupuncture with the needle warmed by burning moxa', and so on being developed except medicinal therapy.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.3
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• pp.62-77
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• 2023

Objectives: The purpose of this study is to investigate the domestic study trends on habitual abortion treated with Korean medicine. Methods: We searched the studies on habitual abortion treated with Korean medicine via searching 5 Korean web databases. After searching studies, we analyzed 7 studies selected according to the selection and exclusion criteria. Results: Of the seven selected studies, five case-reporting studies and two retrospective chart analysis. The most applied intervention for habitual abortion was herbal medication. All patients took herbal medicine before pregnancy, and Seunggum-dan was widely used. 66.3% of pregnant patients after treatment took herbal medicine after pregnancy, and Anjeonyichen-tang was the most widely used. As a result of analyzing retrospective chart analysis studies, whether the patient's age was 35 years or older has a significant impact on the success rate of Korean medicine treatment. Conclusions: This study has provided a basis for using Korean medical intervention in the treatment of habitual abortion in clinical practice. In order to provide a more high-quality basis, reliable follow-up studies related to the effectiveness and stability of Korean medicine treatment for habitual abortion should be conducted in the future.

• The Journal of Korean Obstetrics and Gynecology
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• v.33 no.4
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• pp.143-150
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• 2020

Objectives: The purpose of this study is to report the Pregnancy and delivery in habitual abortion with ectopic pregnancy and loop electrosurgical excision procedure after Korean Traditional Medicine Treatment. Methods: The patient was diagnosed as habitual abortion that had missed abortion three times. She was treated by moxibustion, cupping, acupuncture, Gungguijohyeol-eum-gamibang, and Gwisin-hwan-gamibang for 6 months. The effect of dysmenorrhea was evaluated through the Numeric Rating Scale (NRS). Results: After the treatment, dysmenorrhrea was improved. She was pregnant during the treatment and delivered a child. Conclusions: The case report shows that Korean medical treatment can be helpful for habitual abortion.

• Clinical and Experimental Reproductive Medicine
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• v.26 no.3
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• pp.441-445
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• 1999

Objective: To analyze the methylenetetrahydrofolate reductase (MTHFR) mutation in recurrent spontaneous abortion associated with hyperhomocysteinemia. Material and Method: The blood sample of habitual aborter with high fasting homocysteine level was tested by PCR - RFLP method. Results: The patient was found to be a homozygosity for MTHFR gene mutation that was confirmed by the finding which is consistent with the mutation at the nucleotide 677 C to T, corresponding to Ala to Val. Conclusions: Hyperhomocysteinemia due to MTHFR mutation is a cause of recurrent spontaneous abortion. Therefore, the MTHFR mutation should be examined in the workup of recurrent spontaneous abortion showing hyperhomocysteinemia.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.1
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• pp.1-22
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• 2023

Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of herbal medicine treatment on Antiphospholipid antibody positive recurrent abortion. Methods: We searched for randomized controlled trial of last 20 years based on Antiphospholipid antibody positive recurrent abortion and herbal medicine. The paper search was conducted through 7 online databases on July 16, 2022. Results: 9 studies were selected after selection and exclusion criteria. 5 studies compared combined treatment of herbal and western medicine, with western medicine alone. 4 studies compared herbal medicine alone with western medicine. Comparing with control group, the treatment group showed much improvement on conversion rate of anti-phospholipid antibodies, serum hCG and progesterone levels, pregnancy duration or fertility rates, and various symptoms. Conclusions: In this study, we found out benefit of herbal medicine with Antiphospholipid antibody positive recurrent abortion. For reliable evidence, further research is needed to establish safety of herbal medicines, standardize symptom criteria and specify the treatment course.

• Women's Health Nursing
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• v.1 no.1
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• pp.119-137
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• 1995

Maternity nurses' roles are to find out women's various responses related to the health problems during pregnancy, to intervene adequate nursing and supports, and to help them adapt satisfactorily to new situation, such as hospitalization. The purposes of this study are : firstly, to inquire about women's emotional status, feeling of discomfort, and the nursing need during hospitalization because of discomfort, and the nursing needs during hospitalization because of the possibility of abortion by threatened and habitual abortion : secondly, to provide fundamental data for developing adequate nursing intervention and improving hospital management. The subjects of this study were 62 women who were hospitalized, visited out-patient clinic for follow-up, and stayed at home after discharge since August, 1993 from one hospital located in Seoul, from March 23 to April 13, 1994. The questionnaire was consisted of 21 items of emotion(Reliability Cronbach's alpa, .77), 19 items of feeling of discomfort(.79), and 21 items of nursing needs (.89), and nurses' performance according to nursing needs,(.90). These were measured by using Likert Scale and analyzed by using SPSS / $PC^+$ with the descriptive statistics, $X^2$-test, and ANOVA. Research findings are as follows : 1) The subjects' average age, hospitalized days, and gestational age are 32.2, 15.7, 12.9 by respectively. 2) 88.7% of the subjects are getting antepatal care, 66.1% are experiencing 1.75 times of spontaneous abortion, and 82.3% are nuclear family. 3) The Emotions were mainly comprized negative and subjective state of minds such as uneasiness, anxiety, and discomfort. The domains of emotions were related to 'fetus', 'herself', 'hospitalization', and 'husband's 'families', in rank. The highest scored item was "I, above anyone else, am mostly stressed from abortion." 4) The feelings of discomforts were firstly related to 'personal discomfort arising from absolute bed rest', 'meals provided', Usage of hospital, perse', 'health team', in rank. 5) The nursing needs frequently pointed out were 'Nurses kindly explain of me the purpose, method, and results of the lab. test', 'Nurses sincerely pay attention to my word in communication'. The least nursing needs were 'Nurses observe my feces and whether I have constipation or not'. 'When I can't move, nurses help me by holding my arms or pulling my bed'. 6) The highest performed items were 'Nurses observe whether I bleed or not', and 'Nurses give me drug with exact dose in time'. The least performed items was about hospital environment, such as 'Temperature, ventilation & humidity in the room should be controlled'. 7) Besides religion that is related to nursing need with statistically significant difference, none of general characteristics were related to emotion, feeling of discomfort, and nursing needs.

• Journal of Yeungnam Medical Science
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• v.13 no.1
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• pp.141-145
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• 1996

Habitual pregnancy loss has been defined as three or more consecutive spontaneous abortions. The rate of recurrent pregnancy loss is 2% to 5% of reproducible women. Half of this failure can be explained by genetic, hormonal, infectious, and anatomic factors. And eighty percent of the unexplained failures are proposed to have an immunologic cause. The antiphospholipid antibodies are characterized by prolonged phospholipid-dependent coagulation test (known as APTT or Russel viper venom), thrombosis, thrombocytopenia, and fetal loss. The association of antiphospholipid antibodies with one or more of these characteristic clinical features has been termed the antiphospholipid syndrome. We have experienced a case of successful live birth after treated a woman with heparin and aspirin who has experienced spontaneous abortion four times with antiphospholipid antibodies and present it with the review of literature.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.3
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• pp.185-199
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• 2007

Purpose: This study was designed to establish safety and efficacy of using herbal medicine during pregnancy. Methods : We searched through 23 sources, which had been previously published frome 1988 to 2007, concerned patients that used herbal medicine during pregnancy. We searched diseases for that used herbal medicine, kinds of herbal medicine taken, the period of herbal medicine taken, the duration of herbal medicine taken and results of herbal medicine taken. Results: 1. Whaltae(habitual abortion) was the most of diseases that used herbal medicine during pregnancy. Second disease was hyperemesis gravidum. Third disease was Taegibulan (fetal restlessness). 2. The most of Herb medicines of used for Whaltae was Kyoesamultang and Anjeonecheontang. The most of Herb medicines of used for hyperemesis gravidum was Bosaengtang. The most of Herb medicines of used for Taegibulan was Kyoesamultang. 3. The time of herbal medicine taken mostly was the first period of pregnancy. The rate was 78%. 4. The duration of herbal medicine taken mostly was $18.58{\pm}14.24day$ at mean. 5. The rate of normal delivery was 85% and herbal medication during pregnancy does not cause any deformity to the newborn and of patients used herbal medicine. 6. The patients of taken herbal medicines were recovered from their symptoms and prevented miscarriage. The rate of recovery was 87%. Conclusion: The results of this study show that herbal medication during pregnancy is effective to cure disease and maintain the pregnancy. It is thought that have to actively try to treat diseases and symptoms on pregnancy by using herbal medicine.