• The Journal of Korean Medicine
• /
• v.41 no.3
• /
• pp.151-161
• /
• 2020

Objectives: The purpose of this study is to report the improvement of multiple rib fracture after korean medical treatment; adhesive treatment and herb-medicine treatment. Methods: A patient with multiple rib fracture was treated with Daewhangchija-paste(大黃梔子膏) adhesive and herb-medicine treatment. Verbal numeric rating scale, medical examination by interview and rib series x-ray were used to assess progress of treatment. And we took pictures of left flank after attaching Daewhangchija-paste to observe the changes of the skin colors. Results: Rib series x-ray taken after 2 months of treatment revealed hard callus which added stability against external force on rib cage. After taking off Daewhangchija-paste, left plank skin turned into blue, green and yellow. And the pain level(VNRS) of left plank decreased from 10 to 0.5 for 4 months. Conclusions: Pain reduction on trauma site and improvement of general health condition were observed during combination treatment of Daewhangchija-paste adhesive and herb-medicine.

• Korean Journal of Soil Science and Fertilizer
• /
• v.45 no.6
• /
• pp.1058-1064
• /
• 2012

A green manure crop were used in many ways, such as for reducing chemical fertilizer, improving physical and chemical properties of soils, protecting soil loss, and creating landscape when it's grown in agricultural land. Experiments were conducted to find out carbon emitted with applying green manure crops in paddy field. Amounts of carbon absorbed in the green manure crops during the winter were 1.22 ton $ha^{-1}$ in hairy vetch, 1,24 ton $ha^{-1}$ in barley, and 1.54 ton $ha^{-1}$ in hairy vetch/barley. The soil carbon content was the highest at days before transplanting of rice and decreased after days after harvesting the plant. Soil carbon contents were higher with hairy vetch or barley treatment than with hairy vetch/barley treatment. The content of emitted methane ($CH_4$) was the highest at 7 days after transplanting rice plant, and was 17 ~ 25 times higher with green manure treatments than with chemical fertilizer application. The $CH_4$ emission was the highest with hairy vetch treatment and than followed by hairy vetch/barley and barley treatments. The content of carbon absorbed in rice plant increased during the cultivation period but was not different with the applications of different green manure crops. The yield amounts of rough rice and rice strow were 5 ~ 13% higher with the green manure treatments than the chemical fertilizer application. In particular, they were the highest with hairy vetch/barley treatment as 14.07 ton $ha^{-1}$.

• Journal of the Korean Applied Science and Technology
• /
• v.38 no.3
• /
• pp.870-882
• /
• 2021

Coptis chinensis has been used in the treatment of various diseases such as soothing, anti-inflammation, antimicrobial and antipyretic in oriental traditional medicine. In this study, we investigated the effect of hot water extract of Coptis chinensis(CCW) on skin barrier and inflammation-related factors in UVB and TNF-α/IFN-γ-induced HaCaT cells and evaluated its potential as a moisturizing and anti-inflammatory material. Based on result, the amount of HA (Hyaluronic acid) production and protein and mRNA expression of filaggrin were measured. In TNF-α/IFN-γ-induced HaCaT cells, CCW increased the amount of HA production in a concentration-dependent manner. In the measurement of protein and mRNA expression of filaggrin, the expression rate increased as the concentration of CCW increased. In UVB-induced HaCaT cells, CCW decreased the production of ROS and showed significant results with EGCG ((-)-epigallocatechin-3-gallate), a positive control. In addition, CCW inhibited the expression of inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 in TNF-α/IFN-γ-induced HaCaT cells. It was confirmed that the protein and mRNA expression of COX-2, a major factor in skin inflammation, was decreased in a concentration-dependent manner. These results suggest that hot water extract from Coptis chinensis can be used as a cosmetic material having a moisturizing and anti-inflammatory effect.

• Journal of Animal Environmental Science
• /
• v.6 no.3
• /
• pp.185-190
• /
• 2000

TAO system and solid-liquid separation (28mesh filter and 200mesh filter) were applied in processing piggery slurry to see the reduction of N and P and to draw the efficiency in reducing manure application area. The results are as follows; 1. The amount of N and P in slurry of $4.6m^3/day$ was 22.5kg/day ($4,893mg/{\ell}$) and 7.32kg/day ($1,592mg/{\ell}$). 2. Reduction rate of N and P by TAO reactor was 9.9 kg/day (46.0%) and 3.47kg/day(34.0%). 3. Reduction rate of N and P by Solid-liquid separation was 10.5kg/day (46.6%) and 5.12kg/day (69.8%). 4. One the basis of the amount of nitrogen composting, the square size of liquid manure sprinkled area was reduced from 74.6ha/y to 39.0ha/y in rice paddy, and from 63.2ha/y to 33.0ha/y by the treatment.

• Korean Journal of Pharmacognosy
• /
• v.45 no.3
• /
• pp.256-261
• /
• 2014

Bee venom (BV) therapy has been used as a traditional medicine to treat a variety of conditions, such as arthritis, back pain, cancerous tumors, and skin diseases. However, regulatory effects of BV on tumor necrosis factor (TNF)-${\alpha}$-induced HaCaT cell migration or anti-inflammatory have not been explored. In the present study, we investigated the effects of BV on HaCaT cell migration and anti-inflammation. HaCaT cell migration was evaluated by wound-healing assay. The pro-inflammatory cytokines such as TNF-${\alpha}$, interleukin (IL)-$1{\beta}$, and IL-8 were examined by ELISA or Western blotting. BV treatment led to an increase in migration of HaCaT cells for 24 and 48 h. Especially, 10 ng/ml of BV were significantly increased HaCaT cell migration. Also, BV suppressed the secretion of TNF-${\alpha}$, IL-$1{\beta}$, and IL-8 in culture medium with HaCaT cells. In addition, Western blot results demonstrate that BV suppressed the expression of TNF-${\alpha}$ and IL-$1{\beta}$, in HaCaT cells. Especially, 1 or 10 ng/ml of BV markedly decreased the expression of pro-inflammatory cytokines. These results demonstrate the potential of BV for the prevention of skin inflammation induced by TNF-${\alpha}$.

• Journal of The Korean Society of Grassland and Forage Science
• /
• v.10 no.2
• /
• pp.102-109
• /
• 1990

This experiment was carried out to study the effect of pure mineral nitrogen fertilizing on dry matter yield of grassland and the advisable mineral nitrogen amounts in long duration under practical conditions at the "Federal Institute for Agriculture in the Alps" in Austria. The application rates were 0, 30, 60,90 and 120 kg N/ha/cut, the cutting regimes 3-, 4-, 5- and 6-cuts/year. In order to explain the nitrogen-profitability were determined that 1 kg pure mineral nitrogen have to produce 8 - 16 kg DM/kg N in dependence on cutting regimes and requiring of nitrogen efficiencies. The results were as follows: 1. With only PK-fertilizaing average dry matter yields from 4.0 to 7.6 tons per ha and year were obtained. 2. Within all applied cutting regimes 60 kg min. Nlhalgrowth have proved to be the most efficient application rate witn 13 - 24 kg DM/kg N in dependent of cutting regimes. Comapred with only PK-treatment the DM yields increased by 3.9 - 4.7 t/ ha nad year. 3. By the sigmaformed process of Input-Output curve the highest marginal yield (the "most efficient" Ndressing rate) per ha and year was calculated: 152 kg N at 3-cut regimes, 204 kg N at 4-cut regimes, 220 kg N at 5-cut regimes and 240 kg N/ha/year at 6-cut regimes. 4. With required efficiencies of 16 and 12 kg DM/kg N 240 - 300 kg N per ha and year respectively would have to be applied at 3-cut regimes; with required efficiencies of 12 and 10 kg DM/kg N at 4-cut regimes the appropriate figures ranged from 320 to 420 kg N/ha and year, at 5- and 6-cut regimes and efficiencies of 10 and 8 kg DM/kg N results of 360 - 460 kg N and 380 - 500 kg N respectively were obtained. 5. At the relatively dry location Piber the highest dressing rates were needed in order to obtain the efficiencies from 8 to 16 kg DM/kg N, about 30 - 60 kg N/ha/year more than at the relatively moist location Admont.ist location Admont.

• Applied Chemistry for Engineering
• /
• v.33 no.6
• /
• pp.557-562
• /
• 2022

Hyaluronic acid (HA) is a mucopolysaccharide, occurring naturally in living organisms. It is one of the most hydrophilic molecules, so it has been known as being related to skin hydration and skin aging. The purpose of this study was to examine the effects of Cimicifuga heracleifolia ethanol extract on the hyaluronic acid synthesis and the inhibition of hyaluronidase activity. To determine cytotoxicity, hyaluronic acid synthase 2 (HAS2) gene expression, HA production and, hyaluronidase inhibitory effects, 3-(4,5-dimethylthiazol-2-ly)-2,5-diphenyl tetrazolium bromide (MTT) assay, real time - polymerase chain reaction (RT-PCR), hyaluronic acid enzyme linked immunosorbent assay (HA-ELISA), and hyaluronidase assay were used, respectively. When the Cimicifuga heracleifolia extract was treated in the HaCaT cells up to 500 ㎍/mL concentration, cytotoxicity was confirmed by the Cimicifuga heracleifolia extract at concentrations above 200 ㎍/mL. Therefore, the optimum concentration of all experiments used in this study was determined to be 200 ㎍/mL. HAS2 gene expression increased by Cimicifuga heracleifolia extract in a concentration-dependent manner at all treatment concentrations. The production rate of HA was tended to decrease at the highest concentration of 200 ㎍/mL. The hyaluronidase activity inhibition effect of Cimicifuga heracleifolia extract was very high compared to the control group. Based on these results, Cimicifuga heracleifolia extract was expected to have a moisturizing effect on human skin and special attention should be paid to the determination of the concentration of Cimicifuga heracleifolia when developing cosmetic materials using it.

• Clinics in Shoulder and Elbow
• /
• v.1 no.1
• /
• pp.1-5
• /
• 1998

Rotator cuff disease is the most common cause of shoulder pain. Recent understanding of structure and mechanics enables scientific approach to the treatment of the cuff teat. It is an integral component in the normal movement and function of the shoulder. This article addresses current knowledge of the structure and biomechanics of the rotator cuff, and reviews various kind of operative treatment.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
• /
• 2005.10a
• /
• pp.122-122
• /
• 2005

The remediation for contaminated soil and groundwater in contaminated site and waste site has to be compact and economic in maintaining and operating the system. In this study, the atomized slag was tested if they are an effective reactive material in permeable reactive barrier This novel reactive system technology was applied to the treatment of leachate from unplanned waste landfill. The system was optimized and developed to be commercialized.

• Proceedings of the PSK Conference
• /
• 2003.10b
• /
• pp.203.2-204
• /
• 2003

Nitric oxide (NO) produced in large amounts by inducible nitric oxide synthase (iNOS) is known to be responsible for the vasodilation and hypotension observed in septic shock and inflammation. Inhibitors of iNOS, thus, may be useful candidate for the treatment of inflammatory diseases accompanied by the overproduction of NO. We prepared alcoholic extracts of woody plants and screened the inhibitory activity of NO production in lipopolysaccharide (LPS)-activated macrophages after the treatment of these extracts. (omitted)