• 한국수자원학회논문집
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• 제43권1호
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• pp.25-39
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• 2010

최근 들어 WMS와 ArcHydro 및 HyGIS와 같이 수문학적 지형인자를 생성할 수 있는 GIS 프로그램이 널리 보급되고 있다. 이러한 프로그램에서는 격자형 고도자료인 DEM (Digital Elevation Model)을 이용하여 수자원에서 필요로 하는 다양한 지형인자를 계산할 수 있는 기능을 제공하고 있다. 본 연구에서는 HyGIS로부터 산정된 수문학적 지형인자의 적용성을 평가하기 위해서 국내에서 주로 사용되고 있는 WMS와 ArcHydro를 이용하여 수문학적 지형인자를 산정하고 그 결과를 HyGIS의 계산 결과와 비교 검토하였다. 연구 대상유역으로는 보청천, 위천, 평창강, 경안천, 내린천, 임진강 유역을 선정하였으며, 각 유역에 대해서 추출된 유역의 형태와 함께 유역 면적, 유역 경사, 유역평균고도, 최대유하거리, 최대유하거리 경사, 주하천 길이, 주하천 경사에 대한 산정결과를 비교검토 하였다. 연구결과 전체 유역에 대한 7개의 지형인자의 평균 상대오차는 4.77 %를 나타내었으며, 각 유역에 대해서 추출된 유역 경계 또한 매우 유사하게 생성되었다. 이와 같이 각각의 프로그램은 매우 유사한 지형인자 계산 결과를 나타내고 있으며, 따라서 HyGIS에서 계산된 지형인자는 기존에 국내에서 활용되어 왔던 WMS 및 ArcHydro와 함께 수자원 분야에서 충분히 적용 가능한 것으로 나타났다.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2001년도 추계학술발표대회
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• pp.586-589
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• 2001

본 연구에서는 P. agglomerans를 이용하여 불용성 인산염인 hydroxyapatite 와 인광석을 가용화 하여 유리 인산을 생산하였고, P. agglomerans를 Ca-alginate에 고정화하여 이를 불용성 인산염을 가용화시키는 가능성올 조사하였다. HY 배지에 서 $30^{\circ}C$, lOOrpm 으로 pH 7에서 48시간 배양한 경우 520mg/L 의 유리인산이 생성되었고 hydroxyapatite 대신 같은 농도의 인광석을 첨가하였을때 생성되는 유리 인산 의 양은 86.09mg/L였다. 또한 P. agglomerans를 Ca-alginate에 고정화하였을 때 HY 배지에서 같은 조건으로 120 시간 동안 계속적으로 인산이 생성되었고 , 이때 생성된 인산의 농도는 74Omg/L였으며, 인광석을 첨가한 경우에서도 182mg/L 정도의 유리 인산이 생성되었다.

• Journal of Oral Medicine and Pain
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• 제10권1호
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• pp.17-31
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• 1985

Personality characteristics of TMJ dysfunction patients was studied by means of MMPI test. 100 TMJ dysfunction patients and 100 healthy controls were subjected at the Department of Oral Diagnosis and Oral Medicine, Pusan National University Hospital, during the period from March 1983 to February 1985. All the patients were divided into 2 groups namely, acute group and chronic group by duration of path and discomfort problems for 6 months or longer. The obtained results were as follows : 1. Mean value of T-scores on each clinical scale was within normal range in both patient and control group. 2. There was significant difference in scales of Hs, D. Hy, Pt, Sc and IR between patient and control group. 3. As compared with control group by sexual subclass, scales of Hs, Hy and Pt of both sex, scales of Sc and M-DI of male and scales of D of female in patient group were significantly higher than those in control group 4. The longer was duration of TMJ problems, i.e., in increasing order of control, acute and chronic group, the higher was mean value of T-scores on scales of Hs, D, Hy, Pt, Sc, IR and M-DI. 5. Mean values of T-scores on scales of Hs, D and Hy were the highest in all the clinical scales of total class and subclasses(i. e. male group, female group, acute group and chronic group) with TMJ dysfunction and showed 1-:i-2 (Hs, -Hy, -D. ) profile pattern, conversion "V.ot;V.

• BMB Reports
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• 제46권12호
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• pp.600-605
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• 2013

Interplay between calcium ions ($Ca^{2+}$) and reactive oxygen species (ROS) delicately controls diverse pathophysiological functions of vascular smooth muscle cells (VSMCs). However, details of the $Ca^{2+}$ and ROS signaling network have been hindered by the absence of a method for dual measurement of $Ca^{2+}$ and ROS. Here, a real-time monitoring system for $Ca^{2+}$ and ROS was established using a genetically encoded hydrogen peroxide indicator, HyPer, and a ratiometric $Ca^{2+}$ indicator, fura-2. For the simultaneous detection of fura-2 and HyPer signals, 540 nm emission filter and 500 nm~ dichroic beamsplitter were combined with conventional exciters. The wide excitation spectrum of HyPer resulted in marginal cross-contamination with fura-2 signal. However, physiological $Ca^{2+}$ transient and hydrogen peroxide were practically measurable in HyPer-expressing, fura-2-loaded VSMCs. Indeed, distinct $Ca^{2+}$ and ROS signals could be successfully detected in serotonin-stimulated VSMCs. The system established in this study is applicable to studies of crosstalk between $Ca^{2+}$ and ROS.

• Biomolecules & Therapeutics
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• 제21권4호
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• pp.277-283
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• 2013

In this study, we investigated the effects of a selective urotensin II (UII) receptor antagonist, SB-657510, on the inflmmatory response induced by UII in human umbilical vein endothelial cells (EA.hy926) and human monocytes (U937). UII induced inflammatory activation of endothelial cells through expression of proinflammatory cytokines (IL-$1{\beta}$ and IL-6), adhesion molecules (VCAM-1), and tissue factor (TF), which facilitates the adhesion of monocytes to EA.hy926 cells. Treatment with SB-657510 significantly inhibited UII-induced expression of IL-$1{\beta}$, IL-6, and VCAM-1 in EA.hy926 cells. Further, SB-657510 dramatically blocked the UII-induced increase in adhesion between U937 and EA.hy926 cells. In addition, SB-657510 remarkably reduced UII-induced expression of TF in EA.hy926 cells. Taken together, our results demonstrate that the UII antagonist SB-657510 decreases the progression of inflammation induced by UII in endothelial cells.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2004년도 학술발표회
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• pp.1267-1270
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• 2004

DEM(Digital Elevation Model)을 활용한 기술이 수자원분야에서 필수적인 GIS 활용기술인 이유는 DEM을 이용할 경우 유역의 수문학적 지형특성인자를 객관적인 방법으로 추출할 수 있고 이를 활용하여 분포형 수문모형을 개발, 적용할 수 있기 때문이다. 국내에서도 GIS를 이용하여 수문모형의 입력인자를 추출한 다든가 분포형 수문모형에 대한 연구를 수행할 경우 DEM을 활용한 연구를 수행하고 있다. 이러한 것은 GIS S/W인 Arc/Info, ArcView, WMS 등에서 DEM을 활용하여 수문학적인 유역분석 기능을 제공해 주기 때문에 가능하다. 즉, DEM을 이용하여 하천망을 추출하고, 유역을 분한하고 이를 이용하여 유역 Boundary 내에서의 지형특성인자를 추출하는 기능을 말한다 본 연구는 수자원분야에서 GIS를 활용할 때 필요한 필수기능인 DEM의 활용기술을 순수 국내기술로 개발하였다. DEM활용에 대한 최신 알고리즘을 검토하여 국내 기술로 개발된 GIS Engine인 GEOMaina v.3.0을 이용하여 수문학적인 DEM 활용 Module을 개발하였으며 HyGIS(Hydrologic Geography Information System)라 명하였다. 본 연구에서는 개발된 HyGIS를 이용하여 수문학적 지형특성인자를 추출하고 기존에 사용되어오던 GIS S/W와 비교 검토하여 HyGIS의 환용 가능성에 대하여 검토하고자 한다.

• Journal of Microbiology and Biotechnology
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• 제15권2호
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• pp.362-367
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• 2005

On the basis of high osmotic tolerance and xylitol production, a novel yeast strain was screened from soils of rice farming. The isolated strain HY200 was systematically characterized by using general approaches of Biolog Microlog$^{TM}$ and 18S rRNA sequence analyses, and consequently was designated as Candida tropicalis HY200. Under formulated culture conditions, relatively high xylitol yield ($77\%$) and productivity (2.57 g/l$\codt$h) were obtained, in practice, when 200 g/l of xylose was supplemented. In the utilization of nitrogen, inorganic compounds could not serve as nitrogen sources. As a promising phenotype, HY200 steadily flocculated during and/or after growing in the formulated medium. The extent of flocculation was partly affected by nitrogen sources. However, regardless of the kinds of carbon source fed, the flocculent cells were always observed at the end of the exponential growth phase. These observations strongly suggest that the strain HY200 could effectively be used as a potential candidate for the production of xylitol from xylose, especially in repeated batch mode, because of its flocculation ability and tolerance to high substrate concentrations.

• Nuclear Engineering and Technology
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• 제54권6호
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• pp.2329-2333
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• 2022

Base metal corrosion forms a significant issue during the chemical decontamination of the primary coolant loop in nuclear power plants as it is directly related to the economic and safety viability of decommissioning. In this technical note, potentiodynamic evaluations of several base metals (304 stainless steel, SA106 Grade B carbon steel, and alloy 600) were performed to determine their corrosion behavior during the hydrazine (N₂H₄)-based reductive ion decontamination (HyBRID) process. The results suggested that N₂H₄ protected the surface of the base metals in the HyBRID solution, which is primarily composed of H₂SO₄. The corrosion resistance of the carbon steel was further improved through the addition of CuSO₄ to the solution. The corrosion rate of carbon steel in the H₂SO₄-N₂H₄-CuSO₄ solution was lower than that exhibited in an oxalic acid solution, a commonly used reaction medium during commercial decontamination processes. These results indicate the superiority of the HyBRID process with respect to the base metal stability.

• 한국자원식물학회지
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• 제36권3호
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• pp.198-206
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• 2023

The effectiveness of the extracts of Alnus japonica and Portulaca oleracea, which are effective in improving alcohol-induced liver damage, was confirmed using acute and chronic alcoholic liver injury animal models. In the acute alcoholic liver injury model, dieting Alnus japonica and Portulaca oleracea complex (ALPOC) at a dose of 50 mg/kg showed no significant change in liver or body weight, while measured plasma ALT activity to be deficient (28.12 U/ml) compared to the alcohol intake group (42.5 U/ml), and confirmed that restored it to an average level. It showed an improvement of 34.9% compared to the alcohol intake group. AST activity confirmed that it showed a very effective liver protection activity by showing a gain of 12.6%. The chronic alcoholic liver damage animal model demonstrated that ALT showed an improvement effect of 25%, and AST showed an effect similar to that of the positive control group, Hovenia extract. In addition, through H&E staining analysis, observed that the ALPOC improved the necrosis and bleeding of the liver. And the ALPOC group showed intense antioxidant activity of 127% or more compared to the alcohol intake group, and this was confirmed to have a very high activity, which is more than 20% higher than that of the hovenia fruit extract.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2001년도 추계학술발표대회
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• pp.374-377
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• 2001

답토에서 분리한 균주는 Candida sp. HY200이라 임시 명명하였고, Candida tropocalis 보다 짧은 시간에 xylose를 소모하고, 당내성이 우수하며, flocculation의 특성을 갖고 있다. 260 g/L의 고농도 xylose 배지에서 xylitol 발효는 수율 79%, 생산성 2.14 g/L ${\cdot}$ h의 결과를 얻었다.