• Journal of Microbiology and Biotechnology
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• 제28권1호
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• pp.65-76
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• 2018

Although there has been a steady increase in the prevalence of food allergies worldwide in recent decades, no effective therapeutic strategies have been developed. Modulation of the gut microbiota composition and/or function through probiotics has been highlighted as a promising target for protection against food allergies. In this study, we aimed to investigate the allergy-reducing effects of a probiotic mixture (P5: Lactococcus lactis KF140, Pediococcus pentosaceus KF159, Lactobacillus pentosus KF340, Lactobacillus paracasei 698, and Bacillus amyloliquefaciens 26N) in mice with ovalbumin (OVA)-induced food allergy. Administration of P5 significantly suppressed the oral OVA challenge-induced anaphylactic response and rectal temperature decline, and reduced diarrhea symptoms. Moreover, P5 also significantly inhibited the secretion of IgE, Th2 cytokines (interleukin (IL)-4, IL-5, IL-10, and IL-13), and Th17 cytokines (IL-17), which were increased in mice with OVA-induced food allergy, and induced generation of CD4+Foxp3+ regulatory T cells. These results revealed that P5 may have applications as a preventive agent against food allergy.

• 농업과학연구
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• 제41권4호
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• pp.405-413
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• 2014

The evolutionary history of cattle and buffalo has always been a topic of great interest to the evolutionary biologists. The phylogenetic studies of bovin species has been carried out at various levels, varying from the study of domestication and migration of populations to major cladogenesis. Along with the archeological studies there are studies from molecular biology and more recently from genomics. The phylogenetic perspective of the bovins and their evolutionary history, are reviewed in terms of what has been done, what needs to be done and potential challenges in doing it.

• Journal of Preventive Medicine and Public Health
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• 제32권3호
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• pp.289-296
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• 1999

Objectives: This study describes the risk factors affecting the unexpected readmission of 261 patients who were discharged from a university hospital in Seoul. Methods: This case-control study reviewed medical records of inpatients who had been discharged from a hospital between 1 August 1995 and 31 October 1995 after the treatment for general diseases. The cases were 68 patients who were readmitted unexpectedly within 28 days of discharge from an index stay, and the controls were 193 Patients who were discharged without readmission during the study period. Results: Logistic regression analysis results were as follows; Patients who had no operation during their hospital stay were more likely to be readmitted unexpectedly than patients who had operation. Patients who had 1 or 2 parts of their body being involved in treatment were more likely to be readmitted unexpectedly than patients who hand more than 3 parts of their body being involved in treatment. Patients who had complications after surgery were more likely to be readmitted unexpectedly than patients who had no complications. Insufficient discharge planning caused unexpected readmissions. Conclusions: Discharge planning education should be extended to health care providers. And the assessment of discharge planning should be evaluated. Readmission is often necessary for the treatment of related problems of originating from initial hospitalization, which causes cost problems. Unexpected readmission is preventable and the models for readmission can serve as a valuable clinical tool for high risk patients.

• 한국지능시스템학회논문지
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• 제24권4호
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• pp.450-456
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• 2014

휴머노이드 로봇은 인간-로봇 상호작용에 가장 효과적인 로봇 플랫폼이지만 20개 이상의 관절로 구성되어 있을 만큼 복잡한 구조여서 전통적인 역기구학적 방법으로 안정되면서도 정교한 자세를 생성하기가 어렵다. 본 논문에서는 고속 연산최적화 기법인 Particle Swarm Optimization 기법을 사용해서 앞쪽 지면에 놓인 물체를 단측지지 상태로 상체를 굽혀서 왼팔이나 오른팔로 집는 고난도의 자세를 생성하고, 이를 상용 휴머노이드 로봇 플랫폼에 적용하여 검증함으로써 제안 된 방법의 적용 가능성을 확인한다.

• BMB Reports
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• 제50권8호
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• pp.393-400
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• 2017

Plants are constantly exposed to a variety of abiotic stresses, such as drought, heat, cold, flood, and salinity. To survive under such unfavorable conditions, plants have evolutionarily developed their own resistant-mechanisms. For several decades, many studies have clarified specific stress response pathways of plants through various molecular and genetic studies. In particular, it was recently discovered that ubiquitin proteasome system (UPS), a regulatory mechanism for protein turn over, is greatly involved in the stress responsive pathways. In the UPS, many E3 ligases play key roles in recognizing and tethering poly-ubiquitins on target proteins for subsequent degradation by the 26S proteasome. Here we discuss the roles of RING ligases that have been defined in related to abiotic stress responses in plants.

• 복식
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• 제59권6호
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• pp.16-28
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• 2009

This study examined relationship among fashion product attributes of schoolbag, product satisfaction and repurchase intention. Total 315 questionnaires were distributed to the female/male students in Daegu and GyeongJu. Frequency analysis, factor analysis, reliability analysis, multiple regression were conducted using SPSS 13.0K statistics program as data analysis. The independent sample t-test was also conductd to examine the differences among sex, domicile, middle and highschool students. The findings hum the analysis are described in the following: First, female students is higher subjective fashion product attributes(fashion, individuality, refined) and objective fashion product attributes(design, color) importance than male students in purchasing schoolbag. High school students is higher subjective fashion product attributes(fashion, individuality) and objective fashion product attributes(brand, color) importance than middle school students in purchasing schoolbag. Second, product satisfaction are positive influenced by practicality and individuality of subjective fashion product attributes. Product satisfaction are not influenced by fashion and refined of subjective fashion product attributes. Third, product satisfaction are positive influenced by brand and design of objective fashion product attributes. Product satisfaction are not influenced by price and color of objective fashion product attributes. Forth, repurchase intention in schoolbag are strong positive influenced by product satisfaction.

• 한국수정란이식학회지
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• 제25권3호
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• pp.179-187
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• 2010

Embryonic compaction is essential for normal preimplantation development in mammals. The present study was to investigate the effects of compaction patterns on developmental competence of pig embryos. The proportion of blastocyst formation derived from compacted morula was higher than those of compacting and pre-compacting morula (P<0.01). Nuclei numbers of inner cell mass (ICM), trophectoderm (TE), and total of blastocysts derived from compacted group were also superior to those of compacting and pre-compacting groups (P<0.05). Then, compaction patterns, developmental ability and structural integrity were compared between mono- and poly-spermic embryos. The rate of compacted morula in mono-spermic embryos was higher than that of poly-spermic embryos (P<0.05). Especially, the rate of blastocyst formation derived from compacted embryos in mono-spermic embryo group was higher than that of poly-spermic embryo group (P<0.05), although no difference was detected between the two groups in the structural integrity. Finally, we confirmed that beta-catenin was differentially expressed according to compaction patterns in morula and blastocyst stage embryos. In conclusion, our results suggest that the compaction patterns during preimplantation development play a direct role in developmetal competence and quality of pig embryos.

• The Plant Pathology Journal
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• 제17권4호
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• pp.222-226
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• 2001

In 1997, 103 isolates of Verticillium were obtained from roots and stems of tomato plants showing wilt symptoms in greenhouses in eight areas of Korea. Out of these isolates, 75 were edintified as V. dahliae while 28 were identified as V. albo-atrum based on their morpho-logical and cultural characteristics. Both Verticillium species produced colonies with conidiophores, which were more or less erect, hyaline, with verticillate branches, and with 3-4 phialides at each node. V. dahliae produced microsclerotia, while V. albo-atrum produced resting dark mycelium. Optimum temperatures for mycelial growth of V. dahliae and V. albo-atrum on PDA were 22 and $26^{\circ}$, respectively. Mycelial growth of V. albo-atrum was slower than that of V. dahliae. Pathoge-nicity tests revealed that tomato cvs. Zuikoh No. 102, Kyoryokubeiju No. 2, Zuiken, Kagimuza, and Momotaro were susceptible to V. albo-atrum, while cvs. Zuikoh No. 102 and Kyoryokubeiju No.2 were susceptible to V. dahliae.

• Journal of Preventive Medicine and Public Health
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• 제22권2호
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• pp.236-241
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• 1989

The purpose of this study was to introduce the methodology of intervention analysis with time series data and to investigate the influence of the patient referral system on medical care utilization in Kangwha county. The data were obtained at the Kangwha Medical Inurance Society and we analysed the material based on the outpatient care fee. The results were as fellows: 1. The average outpatient care utilization in the hospital decreased by 41.7% due to the patient referral system. 2. The utilization of the health instituation increased by 278.8 persons per month due to the patient referral system. 3. The patient referral system did not influence the total outpatient are utilization. The methodology of intervention analysis, which detected the effect of intervention, will be helpful to the study of public health area.

• Nutrition Research and Practice
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• 제3권4호
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• pp.259-264
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• 2009

We examined the inhibitory effects of loquat methanol extract on the adhesion, migration, invasion and matrix metalloproteinase (MMP) activities of MDA-MB-231 human breast cancer cell line. Cells were cultured with DMSO or with 10, 25, or 50 ${\mu}g/ml$ of loquat methanol extract. Both leaf and seed extracts significantly inhibited growth of MDA-MB-231 cells in a dose-dependent manner, although leaf extract was more effective. Adhesion and migration were significantly inhibited by loquat extracts in a dose-dependent manner. Loquat extract also inhibited the invasion of breast cancer cells in a dose-dependent manner and leaf extract was more effective than seed extract. MMP-2 and MMP-9 activities were also inhibited by loquat extract. Our results indicate that methanol extracts of loquat inhibit the adhesion, migration and invasion of human breast cancer cells partially through the inhibition of MMP activity and leaf extract has more anti-metastatic effects in cell based assay than seed extract. Clinical application of loquat extract as a potent chemopreventive agent may be helpful in limiting breast cancer invasion and metastasis.