• Title/Summary/Keyword: HSE

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The Effect of Selenium and Vitamin E on Activity of Enzyme Related to the Lipid Peroxidation in Rat with Alcohol Administration (식이내 Selenium과 Vitamin E가 Alcohol을 섭취한 흰쥐의 간 지질 과산화에 관련된 효소의 활성에 미치는 영향)

  • 김갑순;정승용;김석환
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.2
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    • pp.116-126
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    • 1993
  • The purposes of this study were to investigate the effect of seleniumc (Se) and vitamin E on activity of enzyme relevant to lipid peroxidation in alcohol administrated rats. Seventy two male rats of Sprague-Dawley strain weighing about 58~62g were divided into 12groups. The dietary Se levels were 0, 0.4 and 10mg and the dietary vitamin E levels were 0 and 150mg per kg diet, respectively. Alcohol-administrated groups received drinking water solution containing 10% of ethanol from the 3-weeks of experimental periods. The obtained experimental results are summarized as follow: The ${\gamma}$-GTP activity in plasma was higher in alcohol administrated groups and high selenium group (HSe) and low selenium group (LSe) than in control groups (CSe). The ${\gamma}$-GOT and GPT activities were higher in alcohol groups. The ${\gamma}$-GTP activity was significantly influenced by alcohol in LSe groups than in other groups. The glutathione peroxidase (GSH-Px) activity of plasma was significantly lower in LSe groups than HSe and CSe groups. The GSH-Px activity of microsomal and cytosolic fraction was slightly lower in alcohol groups and was about a half value lower in HSe and LSe groups than CSe groups. There was negative correlation between plasma Se level and GSH-Px activity of cytosolic fraction in HSe groups (r=- 0.662, p<0.001) and positive correlation in LSe groups (r=0.640, p<0.001). The GSH S-transferase activity in microsomal and cytosolic fraction was slightly higher in alcohol administrated but vitamin E nonadministrated groups, and significantly higher in LSe groups than in other groups. The catalase activity in mitochondria was lower in HSe than CSe groups, but rather higher in LSe groups. The superoxide dismutase (SOD) activity in cytosolic fraction of liver was not found any effect in all groups. The cytochrome P-450 was higher in alcohol groups, but significantly lower in HSe groups. In conclusion, the deficiency of Se and vitamin E develops the hyperoxidation of liver lipid through the increase of activity of enzyme related to the lipid peroxidation and alcohol administration appears to further increase of hyperoxidation of liver lipid.

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Development and evaluation of a model-based HSE risk assessment module for HSE management in offshore wind power (해상풍력발전의 HSE 관리를 위한 모델기반 HSE 위험성 평가 모듈 개발 및 평가)

  • Seong Rae Kim;Keon Woo Nam;Tae Kyong Lee;Dae Young Kang;Joon Young Kim
    • Journal of the Korean Society of Systems Engineering
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    • v.19 no.2
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    • pp.74-91
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    • 2023
  • This study provides an in-depth comparison and analysis of various risk assessment models widely used in modern industries, and proposes the most suitable model for risk assessment of offshore wind power in Korea. The assessment models were selected by considering various factors such as the purpose of risk assessment, stakeholder requirements, and characteristics of offshore wind power. We also emphasized the importance of using different risk assessment models in combination in situations of high uncertainty. To systematize the combination of risk assessment models, we used systems engineering which is effective to develop a new system. Systems engineering was used to define the complete, traceable functions from site requirements, and model-based systems engineering was used to manage the design information from requirements to detailed functions in a single model. The developed risk assessment module provide automatic conversion between risk assessment models to enable risk assessment suitable for offshore wind power. The functionality and usability of the offshore wind risk assessment module were verified by the evaluation of three wind power experts.

Development of a Work Environment Monitoring System for Improving HSE and Production Information Management Within a Shipyard Based on Wireless Communication (무선 통신 기반 조선소 내 HSE 및 생산정보 관리 향상을 위한 작업환경 모니터링 시스템 개발)

  • Chunsik Shim;Jaeseon Yum;Kangho Kim;Daseul Jeong;Hwanseok Gim;Donggeon Kim;Donghyun Lee;Yerin Cho;Byeonghwa Kim
    • Journal of the Society of Naval Architects of Korea
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    • v.60 no.5
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    • pp.367-374
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    • 2023
  • As the Fourth Industrial Revolution accelerating, countries worldwide are developing technologies to digitize and automate various industrial sectors. Building smart factories not only reduces costs through improved process productivity but also allows for preemptive identification and removal of risk factors through the practice of Health, Safety, and Environment (HSE) management, thereby reducing industrial accident risks. In this study, we visualized pressure, temperature, power, and wind speed data measured in real-time via a monitoring GUI, enabling field managers and workers to easily access related information. Through the work environment monitoring system developed in this study, it is possible to conduct economic analysis on per-unit basis, based on the digitization of production management elements and the tracking of required resources. By implementing HSE in shipyards, potential risk factors can be improved, and gas and electrical leaks can be identified, which are expected to reduce production costs.

Antioxidant and Antiaging Assays of Hibiscus sabdariffa Extract and Its Compounds

  • Widowati, Wahyu;Rani, Andani Puspita;Hamzah, R. Amir;Arumwardana, Seila;Afifah, Ervi;Kusuma, Hanna Sari W.;Rihibiha, Dwi Davidson;Nufus, Hayatun;Amalia, Annisa
    • Natural Product Sciences
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    • v.23 no.3
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    • pp.192-200
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    • 2017
  • Skin aging is a complex biological process due to intrinsic and extrinsic factors. Free radical oxidative is one of extrinsic factors that induce activation of collagenase, elastase and hyaluronidase. Natural product from plants has been used as antioxidant and antiaging. This study aimed to evaluate antioxidant and antiaging properties of Hibiscus sabdariffa extract (HSE) and its compounds including myricetin, ascorbic acid, and ${\beta}$ carotene. The phytochemical of H. sabdariffa was determined using modified Farnsworth method and presence of phenols, flavonoids and tannins were in moderate content, whereas triterpenoids and alkaloids were in low content. Total phenolic content performed using Folin-Ciocalteu method, was $23.85{\mu}gGAE/mg$. Quantitative analysis of myricetin, ${\beta}-carotene$, and ascorbic acid of HSE was performed with Ultra-High Performance Liquid Chromatography (UHPLC) that shows $78.23{\mu}g/mg$ myricetin, $0.034{\mu}g/mg$ ${\beta}-carotene$, whilst ascorbic acid was not detected. HSE has lower activity on DPPH ($IC_{50}=195.73{\mu}g/mL$) compared to ${\beta}-carotene$, the lowest in ABTS assay ($IC_{50}=74.58{\mu}g/mL$) and low activity in FRAP assay ($46.24{\mu}MFe(II)/{\mu}g\;$) compared to myricetin, ${\beta}-carotene$. Antiaging was measured through inhibitory activity of collagenase, elastase, and hyaluronidase. HSE had weakest collagenase inhibitory activity ($IC_{50}=750.33{\mu}g/mL$), elastase inhibitory activity ($103.83{\mu}g/mL$), hyaluronidase inhibitory activity ($IC_{50}=619.43{\mu}g/mL$) compared to myricetin, ${\beta}-carotene$, and ascorbic acid. HSE contain higher myricetin compared to ${\beta}-carotene$. HSE has moderate antioxidants and lowest antiaging activities. Myricetin is the most active both antioxidant and antiaging activities.

One-fluid Conformal Solution Theory for Lennard-Jones Liquid Mixtures (Lennard-Jones 유체 혼합물의 열역학적 연구)

  • Kwon, Yong Jung
    • Journal of Industrial Technology
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    • v.9
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    • pp.119-125
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    • 1989
  • Lennard-Jones 유체 혹은 거의 구형에 가까운 분자들의 혼합물의 열역학적 성질을 예측하기 위한 용액이론이 유도되었다. 이 이론에는 에너지와 분자직경에 대한 두 개의 변수가 존재하며, 강구(hard sphere)를 중심으로 하여 동경함수(pair distribution function)를 확장시키는 교반이론(perturbation theory)에서 1/kT에 대한 일차와 이차계수의 관계로부터 얻어지는 혼합법칙을 이용하는 HSE이론과 달리 Orstein-Zernike결과와 일치되는 분자직경 변수를 먼저 구한 다음, 일차계수와 함께 얻어진 혼합법칙이 유도되었다. 이 방법으로 위 유체들의 혼합물에 적용시켰을 때, 원래의 HSE나 vdW-1의 방법보다 좋은 결과의 열역학적 성질을 예측할 수 있었다.

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Prediction of partial molar volumes of solutes in supercritical CO2 using the Peng-Robinson equation of state with various mixing rules and Kirkwood-Buff solution theory (3차 상태방정식과 여러 혼합법칙 및 Kirkwood-Buff용액이론을 이용한 초임계유체내에서의 용질의 무한희석 부분몰부피의 계산)

  • Jeon, Young-Pyo;Park, Jong-Seon;Kwon, Yong-Jung
    • Journal of Industrial Technology
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    • v.19
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    • pp.253-260
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    • 1999
  • Two thermodynamic models were used to predict the partial molar volumes of solutes in supercritical carbon dioxide at infinite dilution: (1) the Peng-Robinson equation of state with various mixing rules including those based on $EOS/G^E$ (2) the Kirkwood Buff fluctuation integral with the hard sphere expansion (HSE) method. The Kirkwood-Buff fluctuation integral method, in which an equation of state for pure component and molecular parameters are required, produced better results especially near the critical point than the Peng-Robinson equation of state with the several mixing rules based an $EOS/G^E$. When the $EOS/G^E$ mixing rules were used, poorer results were obtained compared with the classical mixing rule and Kirkwood-Buff model.

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Implementation of Human Sensibility Ergonomics Control System (감성제어 시스템의 구현)

  • Kim, Gyu-Sik;Choy, Ick;Ahn, Hyun-Sik
    • Journal of The Institute of Information and Telecommunication Facilities Engineering
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    • v.2 no.2
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    • pp.46-58
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    • 2003
  • The main purpose of developing HSE-based products is to make a human being feel the greatest comfort under the circumstances which vary according to the change of environmental element values. In order to attain a successful achievement, some evaluation and analysis on human sensibility should be proceeded ahead of developing them. In this paper, neural network theories are applied to analyse the structures of comfort sensibility and feeling which are hard to be expressed in mathematical form. In order to verify the performance of the HSE controller, a substitute for a real chamber for simulation is also developed in this study.

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Harmonic State Estimation in Power System (전력시스템 고조파 상태 추정에 관한 연구)

  • Park, H.C.;Lee, J.P.;Wang, Y.P.;Chong, H.H.
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.05a
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    • pp.117-120
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    • 2002
  • Electrical power system has very complexity problem that it is plan measurement system to achieve Harmonic State Estimation (HSE). This complexity problem depends on discord of necessary accuracy, certainty of noise that exist in data communication damage and converter, adaptability of network modification and minimum of expense size of system, estimated monitering. Also, quantity of available measurement equipment for harmonic measurement has been limited. Therefore, systematic method that choose measurement location for harmonic state estimation. This paper is that see proposed HSE that use Observability Analysis(OA) for harmonic state estimation of electrical power system. OA depends on measurement number, measurement location and measurement form here, it is analysis method that depend on network form and admittance of the system. OA used achieve harmonic state estimation that it is Applied to New Zealand electrical power system to prove validity of HSE algorithm that propose. This study result about harmonic state estimation of electrical power system displayed very economical and effective method by OA.

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