• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 A
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• pp.298-300
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• 2002

The design of a measurement system to perform Harmonic State Estimation (HSE) is a very complex problem. In particular, the number of available harmonic instruments(Continuous Harmonic Analysis in Real Time : CHART) is always limited. Therefore, a systematic procedure is needed to design the optimal placement of measurement points. This paper presents a new HSE algorithm which is based on an optimal placement of measurement points using Genetic Algorithms (GAs). This HSE has been applied to the New Zealand AC Power System for the validation of the new HSE algorithm. The study results have indicated an economical and effective method for optimal placement of measurement points using GAs in the HSE.

• 동의생리병리학회지
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• 제19권5호
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• pp.1363-1369
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• 2005

Previously we have shown that shikonin has strong anti-tumor activities via inducing apoptosis and suppressing metastasis on LLC cells in vivo and in vitro. Here we have investigated anti-angiogenic potential of shikonin and its possible mechanism of action in HSE cells. Shikonin inhibited the proliferation of HSE cells in a concentration-dependent manner. It was shown that this proliferation inhibition was caused by apoptosis induced by shikonin via BrdU incorporation and Western blotting analysis. Shikonin treatment was caused that decrease of activation of caspases and cleavage of PARP. And shikonin induced that the activation of mitogen-activated protein kinases (MAPKs), such as extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and p38. Moreover, shikonin showed anti-angiogenic activities inhibiting tube-like formation of HSE cells in vitro and vascular formation of LLC cells in vivo. These findings suggest that shikonin may a possible candidate not only anti-metastatic agent but also anti-angiogenic agent.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 하계학술대회 논문집 A
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• pp.92-94
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• 2003

The design of a measurement system to perform Harmonic State Estimation(HSE) is a very complex problem. In particular, the number of available harmonic instruments (Continuous Harmonic Analysis in Real Time : CHART) is always limited. Therefore, a systematic procedure is needed to design the optimal placement of measurement points. This paper presents an optimal algorithm of HSE which is based on an optimal placement of measurement points using Immune Algorithm (IAs). This HSE has been applied to power system for the validation of an optimal algorithm of HSE. The study results have indicated an economical and effective method for optimal placement of measurement points using IAs in the HSE.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2007년도 제38회 하계학술대회
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• pp.529-530
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• 2007

The design of a measurement system to perform Harmonic State Estimation(HSE) is a very complex problem. In particular, the number of available harmonic analysis measurement instruments is always limited. Therefore, a systematic procedure is needed to design the optimal placement of measurement points. This paper presents an optimal algorithm of HSE which is based on an optimal placement of measurement points using PSO. This PSO-HSE has been applied to power system for the validation of an optimal algorithm of HSE. The study results have indicated an economical and effective method for optimal placement of measurement points using PSO in the HSE.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 하계학술대회 논문집 A
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• pp.286-288
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• 2004

The design of a measurement system to perform Harmonic State Estimation (HSE) is a very complex problem. In particular, the number of harmonic instruments available is always limited. Therefore, a systematic procedure is needed to design the optimal placement of measurement points. This paper presents a new HSE algorithm which is based on an optimal placement of measurement points using Genetic Algorithms (GAs). This HSE has been applied to the Simulation Test Power System for the validation of the new HSE algorithm. The study results have indicated an economical and effective method for optimal placement of measurement points using Genetic Algorithms (GAs) in the Harmonic State Estimation (HSE).

• 대한전기학회논문지:전력기술부문A
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• 제52권8호
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• pp.471-480
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• 2003

The design of a measurement system to perform Harmonic State Estimation (HSE) is a very complex problem. Among the reasons for its complexity are the system size, conflicting requirements of estimator accuracy, reliability in the presence of transducer noise and data communication failures, adaptability to change in the network topology and cost minimization. In particular, the number of harmonic instruments available is always limited. Therefore, a systematic procedure is needed to design the optimal placement of measurement points. This paper presents a new HSE algorithm which is based on an optimal placement of measurement points using Genetic Algorithms (GAs) which is widely used in areas such as: optimization of the objective function, learning of neural networks, tuning of fuzzy membership functions, machine learning, system identification and control. This HSE has been applied to the Simulation Test Power System for the validation of the new HSE algorithm. The study results have indicated an economical and effective method for optimal placement of measurement points using Genetic Algorithms (GAs) in the Harmonic State Estimation (HSE).

• Animal cells and systems
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• 제4권2호
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• pp.181-186
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• 2000

The expression of $p21^{WAF1/ClP1/SDl1}$, one of the cyclin-dependent kinase inhibitors, is regulated by a variety of transcription factors including p53 and STAT. Heat shock induces the expression of p21 in a temperature- and time-dependent manner. Although the p21 induction by heat shock has been reported to be controlled by p53, a p53-independent mechanism Is also involved. To understand the p53-independent regulation of heat shock-induced p21 expression, we searched the promoter region of p21 gene and found one or two heat shock element (HSE)-like sequences in human, rat, and mouse. Electromobility shift assay (EMSA) showed that heat shock factor (HSF) could bind to these HSE-like sequences In response to heat shock, even though to a lesser extent than to HSE. In addition, p21 promoter deletion analysis revealed that heat shock activated a p21 deletion promoter construct containing the HSE-like sequences but lacking p53-binding sites, but not a promoter construct containing neither HSE-like sequences nor the p53-responsive element. Furthermore, the p21 induction by heat shook was significantly inhibited in confluent cells in which heat shock-induced HSF activation was reduced. These results suggest that the transcriptional regulation of p21 by heat shock may be mediated through activation and binding to HSE-like sequences of HSF.

• Bulletin of the Korean Chemical Society
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• 제33권6호
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• pp.1839-1844
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• 2012

We have investigated binding between wild-type and mutant Heat Shock Factor (HSF) DNA binding domains (DBDs) with 17-bp HSE containing a central 5'-NGAAN-3' element by equilibrium analytical ultracentrifugation using multi-wavelength technique. Our results indicate that R102 plays critical role in HSE recognition and the interactions are characterized by substantial negative changes of enthalpy (${\Delta}H^0_{\theta}=-9.90{\pm}1.13kcal\;mol^{-1}$) and entropy (${\Delta}S^0_{\theta}=-12.46{\pm}3.77cal\;mol^{-1}K^{-1}$) with free energy change, ${\Delta}G^0_{\theta}$ of $-6.15{\pm}0.03kcal\;mol^{-1}$. N105 plays minor role in the HSE interactions with ${\Delta}H^0_{\theta}$ of $-2.54{\pm}1.65kcal\;mol^{-1}$, ${\Delta}S^0_{\theta}$ of $19.28{\pm}5.50cal\;mol^{-1}K^{-1}$ and ${\Delta}G^0_{\theta}$ of $-8.35{\pm}0.05kcal\;mol^{-1}$, which are similar to those observed for wild-type DBD:HSE interactions (${\Delta}H^0_{\theta}=-3.31{\pm}1.86kcal\;mol^{-1}$, ${\Delta}S^0_{\theta}=17.38{\pm}6.20cal\;mol^{-1}K^{-1}$ and ${\Delta}G^0_{\theta}=-8.55{\pm}0.06kcal\;mol^{-1}$) indicating higher entropy contribution for both wild-type and N105A DBD bindings to the HSE.

• 예술인문사회 융합 멀티미디어 논문지
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• 제8권5호
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• pp.407-416
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• 2018

현대사회의 빠른 발달로 인해 웨어러블 장비가 탄생했고 빠르게 성장 중에 있다. 웨어러블 장비는 신체에 착용하는 특성으로 인해 경량, 소형 및 저전력을 만족해야 한다. 본 논문에서는 웨어러블 장비의 개요를 기술하였고, 웨어러블 장비 분야의 시장현황을 조사하였다. 또한 기존 개발된 웨어러블 컴포넌트 기술에 대한 사례 및 웨어러블 통신기술을 조사하였다. 한편 산업현장에서의 중대산업재해에 대한 사회적 관심으로 인한 스마트 HSE 시스템의 구축이 요구되었으며, 결합 되었을 경우 효과적으로 안전관리가 이루어 질 것으로 예상되는 웨어러블 장비와 스마트 HSE 시스템을 접목하는 방안을 제시하였다. 이를 위해 조선해양 분야의 용접작업장 위험요소를 도출하고, 용접작업장에서의 위험 시나리오를 작성하여 위험을 줄일 수 있는 웨어러블 장비 접목 방안을 제시하였다. 또한 웨어러블 장비가 적용된 위험 시나리오를 통해 위험이 저감될 수 있음을 보였다. 본 논문에서 제안한 웨어러블 장비와 HSE 시스템 연동방안을 통해 보다 안전하고, 사고 발생 시에는 신속한 대응으로 작업자 안전이 확보될 것으로 기대된다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제10권3호
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• pp.205-211
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• 2005

Water-soluble polyethyleneimine (PE) derivatives containing nucleic acid bases and hydrophilic amino acids such as homoserine (Hse) and serine were prepared by the activated ester method as nucleic acid models. From spectroscopic measurements, the polymers were found to interact with DNA accompanied by an induction of conformational change. Hypochromicity in UV spectra indicated that a stable polymer complex was formed between poly (A) with PEI­Hse-Ura by complementary hydrogen bonding with equimolar nucleic base units (adenine:uracil=1:1). The induced conformation of DNA by the interaction with the polymer containing uracil and homoserine (PEI-Hse-Ura) was concluded to be a super triple helical structure. The formation of the polymer complex, DNA: PEI-Hse-Ura, was found to be affected by the presence of metal ions such as $Ca^{2+}\;and\;Cu^{2+}$.