• 근관절건강학회지
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• 제29권1호
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• pp.41-49
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• 2022

Purpose: The purpose of this study was to assess the influence of nurses staffing level on patient health outcomes in intensive care units (ICUs) in Korea. Methods: The study was retrospective in nature. Information on patients and their outcomes, as well as nurse cohort data, were obtained from Korea's National Health Insurance Service Database. The observation period was from January 1, 2008 to December 31, 2018, and data for 2,964,991 patients were analyzed. Independent variables included patient' age and sex and hospital type, intensivist, and nurses staffing level. Results: The mortality rate in ICUs was significantly higher at tertiary hospitals with a level 3~4 (HR, 1.21; 95% confidence interval, 1.19~1.22) or level 5~9 nurse staffing (HR, 1.31; 95% confidence interval, 1.27~1.34) compare to that of tertiary hospitals with a 1~2 level. 28-day mortality rate was also higher at general hospitals with a level 3~4 (HR, 1.13; 95% confidence interval, 1.12~1.14), level 5~6 (HR. 1.34; 95% confidence interval, 1.32~1.36), level 7~9 nurse staffing (HR, 1.38; 95% confidence interval, 1.38~1.42), using level 1~2 as reference. Conclusion: Nurses staffing level is a key determinant of healthcare-associated mortality in critically ICUs patients. Policies to achieve adequate nurse staffing levels are therefore required to enhance patient outcomes.

• 한국정보시스템학회지:정보시스템연구
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• 제31권4호
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• pp.145-160
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• 2022

Purpose The purpose of this study is to develop a virtual try-on deep learning model that can efficiently learn front and back clothes images. It is expected that the application of virtual try-on clothing service in the fashion and textile industry field will be vitalization. Design/methodology/approach The data used in this study used 232,355 clothes and product images. The image data input to the model is divided into 5 categories: original clothing image and wearer image, clothing segmentation, wearer's body Densepose heatmap, wearer's clothing-agnosting. We advanced the HR-VITON model in the way of Mixed-Precison, Gradient Accumulation, and sharing model weights. Findings As a result of this study, we demonstrated that the weight-shared MP-GA HR-VITON model can efficiently learn front and back fashion images. As a result, this proposed model quantitatively improves the quality of the generated image compared to the existing technique, and natural fitting is possible in both front and back images. SSIM was 0.8385 and 0.9204 in CP-VTON and the proposed model, LPIPS 0.2133 and 0.0642, FID 74.5421 and 11.8463, and KID 0.064 and 0.006. Using the deep learning model of this study, it is possible to naturally fit one color clothes, but when there are complex pictures and logos as shown in <Figure 6>, an unnatural pattern occurred in the generated image. If it is advanced based on the transformer, this problem may also be improved.

• The Korean journal of internal medicine
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• 제39권2호
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• pp.228-237
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• 2024

Background/Aims: Long-term use of acid suppressants such as proton pump inhibitors (PPIs) and histamine 2 receptor antagonist (H2RA) has been associated with the risk of osteoporotic fracture. Acid suppressants and muco-protective agents (MPAs) are often used together as anti-ulcer agents. We evaluated the association between the risk of osteoporotic fracture and the combined use of these anti-peptic agents. Methods: A population-based case-control study was conducted by analyzing the Korean National Health Insurance Data from 2014 to 2020. Patients who had been prescribed anti-peptic agents, such as PPI, H2RA, or MPA, were included. Considering the incidence of osteoporotic fractures, the case group (n = 14,704) and control group (n = 58,816) were classified by 1:4 matching based on age and sex. Results: The use of all types of anti-peptic agents was associated with an increased risk of osteoporotic fractures (PPI: hazard ratio [HR], 1.31; H2RA: HR, 1.44; and MPA: HR, 1.33; all p < 0.001). Compared to PPI alone, the combined use of "PPI and H2RA" (HR, 1.58; p = 0.010) as well as "PPI, H2RA, and MPA" (HR, 1.71; p = 0.001) was associated with an increased risk of osteoporotic fracture. However, compared with PPI alone, "MPA and PPI or H2RA" was not associated with an increased risk of osteoporotic fracture. Conclusions: This study found that the combined use of "PPI and H2RA" was associated with a higher risk of osteoporotic fractures. In cases where deemed necessary, the physicians may initially consider prescribing the combination use of MPA.

• 대한공간정보학회지
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• 제15권4호
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• pp.111-116
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• 2007

본 연구의 목적은 DGPS와 음향측심기를 장착한 소형의 로봇선을 이용하여 저수지의 수심정보를 획득하고 이를 이용하여 정확도를 분석하는데 있다. 즉 로봇선의 속도를 변화시키고 이에 따른 속도별 수심측정의 정확도를 분석하였다. 현장실험 결과, 로봇선의 속도가 느릴수록 수심측정의 오차가 적었으며, 로봇선의 속도가 5km/hr까지는 정규분포의 신뢰구간인 95% 이내에 포함되는 것을 알 수 있었다.

• 약학회지
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• 제53권6호
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• pp.314-320
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• 2009

We examined metabolic conversion of cysteine into glutathione (GSH) and taurine in rat liver under oxidative stress. Administration of tert-butylhydroperoxide (t-BHP) into the portal vein of male rats resulted in a rapid elevation of serum sorbitol dehydrogenase, alanine aminotransferase, and aspartate aminotransferase activities, which decreased gradually in 24 hr. Hepatic cysteine concentration was reduced in 3 hr, and recovered progressively, reaching a level greater than 200% of the normal value in 24 hr. GSH was increased both in liver and blood at 9 hr after t-BHP challenge, whereas hypotaurine or taurine was not altered. $\gamma$-Glutamylcysteine synthetase (GCS) activity was increased from 9 hr after t-BHP treatment, but protein expression of the GCS-heavy subunit was not changed in liver. Activity or expression of cysteine dioxygenase was not affected by t-BHP treatment. Taken together, these data show that an acute oxidant challenge to the rats may induce upregulation of cysteine availability and GCS activity, resulting in an enhancement of hepatic GSH synthesis, but the increased cysteine level does not stimulate taurine synthesis via cysteine sulfinate pathway. It is indicated that the regulation of GSH and taurine biosynthesis from cysteine is not solely dependent on the cysteine concentration in rat liver under oxidative stress.

• 한국축산식품학회지
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• 제18권2호
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• pp.142-148
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• 1998

This study was conducted to investigate the quality change of beef muscle, which was thawed by different thawing rate in order to utilize it as fundamental data for establishing optimal and thawing condition. Chilled beef round which was purchased at a commercial market was used. The samples were frozen for 30min(time required to pas through the maximal ice forming zone, -1$^{\circ}C$∼-7$^{\circ}C$) and the thawing conditions were 3.9cm/hr, 0.21cm/hr, 0.13cm/hr. Thawing losses of rapidly thawed meat(3.9cm/hr) were significantly(p＜0.05) lower(6.10%), but cooking and total losses were the highest as 48.17% and 56.44%, respectively(p＜0.05). Characteristics such as color, flavor, texture and overall quality at different the thawing rates showed similar scores, but slightly increased after storage for 24hr. Juiciness of rapidly thawed meat was significantly(p＜0.05) higher than that compared to the other thawing rates.

• 지역사회간호학회지
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• 제22권4호
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• pp.365-376
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• 2011

Purpose: The purpose of this study was to investigate the patterns of smoking relapse and to identify risk factors related to smoking relapse among those successful in smoking cessation at the smoking cessation clinics of public health centers. Methods: Data were collected from 1,705 six-month quitters and analyzed by the Kaplan-Meier analysis and the Cox proportional hazard model. Results: The rate of smoking relapse was 38.2% in 1 year, 44.4% in 2 years, and 47.8% in 5 years. The vast majority of relapse (62.3%) occurred within the first six months after quitting. The risk factors related to smoking relapse were age (HR 1.964: 95% CI 1.545, to 2.497), nicotine dependence (HR 1.293: 95% CI 1.087 to 1.539), problem drinking (HR 1.497: 95% CI 1.116 to 2.008), behavioral therapy type (HR 1.398: 95% CI 1.193 to 1.638), and nicotine replacement therapy type (HR 1.363: 95% CI 1.077 to 1.724). Conclusion: For reducing smoking relapse, it is necessary to develop a smoking relapse prevention program for the first six months after quitting and to strengthen behavioral therapy in the course of smoking cessations clinics.

• Journal of Astronomy and Space Sciences
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• 제35권4호
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• pp.295-308
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• 2018

In this study, orbit determination (OD) simulation for the Korea Pathfinder Lunar Orbiter (KPLO) was accomplished for investigation of the observational arc-length effect using a sequential estimation algorithm. A lunar polar orbit located at 100 km altitude and $90^{\circ}$ inclination was mainly considered for the KPLO mission operation phase. For measurement simulation and OD for KPLO, the Analytical Graphics Inc. Systems Tool Kit 11 and Orbit Determination Tool Kit 6 software were utilized. Three deep-space ground stations, including two deep space network (DSN) antennas and the Korea Deep Space Antenna, were configured for the OD simulation. To investigate the arc-length effect on OD, 60-hr, 48-hr, 24-hr, and 12-hr tracking data were prepared. Position uncertainty by error covariance and orbit overlap precision were used for OD performance evaluation. Additionally, orbit prediction (OP) accuracy was also assessed by the position difference between the estimated and true orbits. Finally, we concluded that the 48-hr-based OD strategy is suitable for effective flight dynamics operation of KPLO. This work suggests a useful guideline for the OD strategy of KPLO mission planning and operation during the nominal lunar orbits phase.

• 한국산학기술학회논문지
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• 제13권10호
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• pp.4653-4659
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• 2012

본 연구는 보건소 금연클리닉의 6개월 금연성공자의 금연지속 실패와 관련된 요인을 파악하고자 시도되었다. 자료는 6개월 금연성공자 347명으로부터 보건소 금연클리닉 등록카드와 전화설문 조사를 통하여 수집되었으며, 생명표법과 Cox-proportional hazard model로 분석하였다. 금연지속 실패와 관련된 요인은 주거지가 읍 면인 경우(HR 2.50, 95% CI 1.69-3.68), 만성질환이 없는 경우(HR 1.92, 95% CI 1.21-3.04), 동거가족 흡연자가 없는 경우(HR 1.93, 95% CI 1.21-3.09) 금연보조제를 사용한 경우(HR 2.17, 95% CI 1.01-4.68)로 나타났다. 누적 금연지속 실패율은 6개월까지가 28.6%, 24개월은 36.1%로 나타났다. 이에 보건소 금연클리닉은 금연성공 및 금연 지속률을 높이기 위하여 대상자의 금연의지를 강화할 수 있는 다양한 중재 개발이 필요하다.

• 한국환경보건학회지
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• 제44권2호
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• pp.143-152
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• 2018

Objectives: The purpose of this study was to provide basic data for air pollutant exposure modelling and understanding the contribution of respective microenvironments by assessing the time-activity patterns of Korean students according to variables such as grade, sex, weekday, and weekend. Methods: In this study, we compared the residential time of 521 (both weekday and weekend) lower elementary students, 1,735 (1,054 on weekdays, 681 on weekends) upper elementary students, 2,210 (1,294 on weekdays, 916 on weekends) middle school students, and 2,366 (1,387 on weekdays, 979 on weekends) high school students in different microenvironments according to grade, sex, weekday, and weekend. We used data from the 2014 Time-Use Survey by the Korean National Statistical Office for upper elementary students through high school students, and surveyed time-activity patterns of 521 lower elementary students aged 7-9 years. Each microenvironment was divided into indoor, outdoor, and transport. Indoor environments were divided into home, school, and other places. In addition, the results of previous studies were compared to this study. Results: Weekday time-activity patterns of Korean students indicated that lower elementary students spent $16.02{\pm}2.53hr$ in the home and $5.37{\pm}2.32hr$ in school. Upper elementary students spent $14.11{\pm}1.79hr$ in the home and $6.27{\pm}1.37hr$ in school. Middle school students spent $12.83{\pm}2.22hr$ in the home and $7.48{\pm}1.88hr$ in school. High school students spent $10.65{\pm}2.86hr$ in the home and $10.23{\pm}2.86hr$ in school on weekdays. High school students spent the least amount of time in the home and the most time in school compared to other grades Conclusions: Students spent most of their time indoors, including in the home, school, and other indoors. On weekdays, as the grade increases, home residential times were decreased and school residential times were increased. Differences in time-activity patterns according to sex were not found for either weekdays or weekends. It is estimated that Korean students could be affected by school indoor air quality. High school students could be most affected by school indoor air quality since they spent the most time at school.