• The Korean Journal of Pharmacology
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• v.22 no.2
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• pp.88-95
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• 1986

Clinically, subhypnotic doses of barbiturates have been known to elicit hyperalgesia. In this experiment, effect of acute or chronic phenobarital treatment on the response to pain in rat was reevaluated by hot-plate method. To elucidate its mechanism, changes of ${\beta}-endorphin$ contents and [3H]-morphine binding of the rat midbrain as well as functional opiate receptor in vas deferens were also measured. Intraperitoneal injection of sub anesthetic dose phenobarbital induced initial hyperalgesia followed by successive analgesia, while chronic phenobarbital-treatment decreased reactivity to pain. Naloxone (10mg/kg, i.p.) markedly shortened hot plate latency period, and significantly inhibited the analgesic action of phenobarbital. Single dose of phenobarbital did not affect ${\beta}-endorphin$ contents and [3H]-morphine binding in rat mid brain, but in the chronic phenobarbital-treated groups, ${\beta}-endorphin$ contents was increased, while Bmax of opiate receptor binding was decreased. Moreover, very significant correlations among responses to pain, changes of ${\beta}-endorphin$ contents and opiate receptor binding were observed. However, Kd values of opiate receptor bindings were not changed in all preparations. In the chronic phenobarbital-treated vas deferens preparations, ID50 of morphine was increased witb concomittant decrease of maximum effect. But $pA_2 $, value for naloxone was not changed. From these results, it is suggested that phenobarbital can produce analgesia due to changes of ${\beta}-endorphin$ contents as well as functional opiate receptors by receptor regulation.

• Korean Journal of Occupational Health Nursing
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• v.21 no.1
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• pp.37-45
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• 2012

Purpose: This study was conducted to identify health promotion lifestyle (HPL), farmers' syndrome and related factors of workers in agricultural industry. Methods: A total of 454 agricultural workers were selected through convenient sampling. Data were collected from July 1 to August 10, 2009. Data analysis included frequency, t-test, ANOVA, Scheff$\acute{e}$ test, and stepwise multiple regression using SPSS/WIN 17.0. Results: 1. The mean score of HPL was 3.30 and the prevalence of farmers' syndrome was 29.3%. 2. Analysis of farmers' syndrome showed there were statistically significant differences for gender, age, sleeping time, perceived health status, breakfast and exercise. 3. Gender, age, perceived health status, breakfast and exercise were identified as variables influencing the farmers' syndrome. Conclusion: This study suggested that we should develop health promotion programs for workers of agricultural industry considering these results.

• Clinical and Experimental Reproductive Medicine
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• v.4 no.1
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• pp.27-32
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• 1977

Serum levels of human placental lactogen were measured by hemagglutination inhibition reaction in 26 normal pregnant state and in patients with 16 toxemia and 6 F.D.I.U. beyond their thirtieth week of gestation to evaluate their clinical usefulness. It was realized that HPL-HAIR Test Kit was easy to use and produced reliable results. The general conclusion were as follows: 1) HPL value was $6{\sim}8$ug/ml in normal pregnancy. 2) The levels in mild toxemia were similar in the normal state. 3) The levels in severe toxemia were similar or slightly lower than in the normal and mild toxemia. 4) The levels in F.D.I.U. were lower than in the normal state.

• Korean Journal of Occupational Health Nursing
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• v.7 no.1
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• pp.33-46
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• 1998

Introduction : In Korea, national attention to the workplace health promotion programs (HPP) for employees began in early 1990s. Governmental supports for the HPP and education programs have given to the employees. The purpose of this study is to find the performance degree of employees' health promoting lifestyle(HPL). Subjects and Methods : For this study, 615 employees who attended governmental educations were selected as research samples. The tool for measuring HPL used in this study was developed for Korean by In-Sook Park in 1995. It is composed of 4-point scaled 60 items and divided into 11 subcategories. The data were collected by self reporting questionnaires from June to December in 1997. Those data were analyzed percentile, mean, standard deviation, ANOVA, t-test with SAS program. Major findings are as follows; 1. The total mean score of the employees' HPL performance was 2.66. The average scores of 'harmonious relationships' category were the highest as 3.11, whereas the one of 'professional health maintenance' were the lowest as 2.02. The remains were 'sanitary life'(2.90), 'emotional support(2.85), 'regular diet'(2.84), 'self achievement'(2.78), 'healthy diet'(2.56), 'rest and sleep'(2.56), 'exercise and activity'(2.54), 'diet control'(2.53), 'self-control'(2.52). 2. The factors affecting HLP were category of industries and sex, age, marital status, education level, major, educational experience of health promotion, among personal characteristics. The employees of service industries, female, older age, married, nurse, educated for health promotion, graduated from junior college performed HLP more than the others. 3. The participation rates of employees for HPP were 12.4%, because of limited time and facilities and equipments. Recommendations; 1. The regulation for performing the health promotion programs in the industries is essential for activating industrial health promoting movement. 2. More governmental supports for educations and services for health promotion programs in the industries are needed. 3. For behavioral changes of the employees, the contents of educations have to consist of exercise and activity, rest and sleep, diet and smoking habits. 4. The evaluating studies for ready made health promotion programs in the industries are expected.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2004.11a
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• pp.166-169
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• 2004

In the International Code of Practice for dosimetry TRS-398 published by International Atomic Energy Agency(IAEA), water equivalency plastic phantom may be used under certain circumstances for electron beam dosimetry for beam quality E0${\leq}$ 10 MeV. In this study, Palstic Water$^{TM}$ and Virtual Water$^{TM}$ were evaluated in order to determine fluence scaling factor hpl. Plastic phantom was evaluated for five electron energy from 6 MeV to 20 MeV. From the measured data of Palstic Water$^{TM}$, the fluence scaling factor hpl was found to be average 0.9964 and Virtual Water$^{TM}$ fluence scaling factor was 1.0156.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.5
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• pp.525-531
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• 2011

Exhaust gas recirculation (EGR) is more effective than selective catalytic reduction (SCR) or lean $NO_x$ trap (LNT) for the reduction of $NO_x$ emissions in diesel engines. A large amount of EGR gas is necessary to satisfy the stringent regulations on $NO_x$ emissions. Low pressure loop (LPL) EGR is almost independent of the variable geometry turbocharger (VGT) at a specific boost pressure, so LPL EGR is better than conventional high pressure loop (HPL) EGR in terms of EGR supply. We compare the influence of HPL EGR and LPL EGR on the combustion characteristics at a constant boost pressure in a diesel engine. The dilution ratio was employed as an independent parameter to analyze the effect of the dilution of the intake charge for each EGR loop. At the same level of $NO_x$ emissions, the fuel consumption and smoke opacity were slightly lower for LPL EGR than for HPL EGR.

• The Journal of the Korean Society for Microbiology
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• v.35 no.4
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• pp.283-288
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• 2000

The PCR primer set JW21-JW22 of Weiss et al. (19), which was reported to amplify a 139-bp fragment of the l6S rRNA gene of Helicobacter pylori, has been recently used for the detection of H. pylori in clinical specimens. However, when we applied JW21-JW22 PCR to other members of the genus Helicobacter and unrelated microorganisms, all of these bacteria produced a 139-bp PCR product. Therefore, we designed a novel primer set, HPU185-HPL826, which produced a 642-bp amplicon of the l6S rRNA gene of H. pylori. Then we further examined the specificity of the novel PCR assay using Southern blot hybridization with an internal probe, HPP225. The PCR assay described in this study was shown to be highly sensitive and specific only to the H. pylori 16S rRNA gene sequences.

• Korean Journal of Health Education and Promotion
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• v.20 no.2
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• pp.179-196
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• 2003

This study was aimed at examining the self-reported health-promoting life- style (HPL) and related factors among teachers assumed to be role models for students. The subjects were 300 teachers who were conviently drawn from nine elementary schools and three high schools. The conceptual framework for this study was based on the Pender's revised Health Promotion Model(1996). Data was collected by a mailed survey (response rate, 62.5％) with structured questionnaire. The score of health-promoting life-style was 2.8(full mark： 5.0), harmonized relationship was the highest(3.2), and professional helath management was the lowest(2.0). The related factors to health-promoting life-styles were age, marital stauts, career, perceived health status, self esteem, intermal locus of control, perceived benefit, perceived barrier, self efficacy, and social support in univariate analysis. In the final regression model, predictors of HPL were social support, self esteem, perceived benefit. self efficacy, and perceived health status after control the effects of demographic characteristics (p＜.0001, R2＝0.494). The results generally supported the Pender Model. It is recommended to develop the health promotion program for teachers based on these results, and to evaluate the effect of that program for teacher.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.1
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• pp.105-109
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• 2015

This paper presents the results of an experimental analysis of the high-power laser (HPL)-induced damage to a complementary metal-oxide semiconductor (CMOS) image sensor. Although the laser-induced damages to metallic materials have been sufficiently investigated, the damages to electric-optic imaging systems, which are very sensitive to HPLs, have not been studied in detail. In this study, we experimentally analyzed the HPL-induced damages to a CMOS image sensor. A near-infrared continuous-wave (CW) fiber laser was used as the laser source. The influences of the irradiance and irradiation time on the permanent damages to a CMOS image sensor, such as the color error and breakdown, were investigated. The experimental results showed that the color error occurred first, and then the breakdown occurred with an increase in the irradiance and irradiation time. In particular, these damages were more affected by the irradiance than the irradiation time.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.11
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• pp.4137-4144
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• 2010

In this study, the simulations were carried out to show the effect of the EGR configuration in a passenger diesel engine with 2-stage turbocharger on the EGR rate. The AMESim and IFP Engine Library were used to make the program for the simulation. Three EGR configurations, HPL(high pressure loop), LPL(low pressure loop), and SLPL(semi low pressure loop), were considered. The EGR rate in the HPL and LPL EGR routes were 6.4% and 10.0% respectively but the rate in SLPL route was 18.0% and their air/fuel ratio for all three cases was 21. Therefore the SLPL EGR configuration may be positively considered in the design of the passenger diesel engine with 2-stage turbocharger.