• Title/Summary/Keyword: HMT

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Heterologous Expression of Fission Yeast Heavy Metal Transporter, SpHMT-1, Confer Tolerance to Cadmium in Cytosolic Phytochelatin-Deficient Saccharomyces cerevisiae (분열효모 SpHMT1을 세포질 파이토킬레이트를 생성하지 않는 효모에서 발현으로 인한 카드뮴에 대한 저항성 증가)

  • Lee, Sang-Man
    • Journal of Life Science
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    • v.19 no.12
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    • pp.1685-1689
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    • 2009
  • Phytochelatins (PCs) are small polypeptides synthesized by PC synthase (PCS). They are present in various living organisms including plants, fission yeast, and some animals. The presumed function of PCs is the sequestration of cytosolic toxic heavy metals like cadmium (Cd) into the vacuoles via vacuolar membrane localized heavy metal tolerance factor 1 (HMT-1). HMT-1 was first identified in fission yeast (SpHMT-1), and later in Caenorhabdtis (CeHMT-1). Recently, its homolog has also been found in PC-deficient Drosophila (DmHMT-1), and this homolog has been shown to be involved in Cd detoxification, as confirmed by the heterologous expression of DmHMT-1 in fission yeast. Therefore, the dependence of HMT-1 on PC in Cd detoxification should be re-evaluated. I heterologously expressed SpHMT-1 in cytosolic PC-deficient yeast, Saccharomycea cerevisiae, to understand the dependence of HMT-1 on PC. Yeast cells expressing SpHMT-1 showed increased tolerance to Cd compared with control cells. This result indicates that SpHMT-1 is not strictly correlated with PC production on its function. Moreover, yeast cells expressing SpHMT-1 showed increased tolerance to exogenously applied glutathione (GSH) compared with control cells, and the tolerance to Cd was further increased by exogenously applied GSH, while tolerance in control cells was not. These results indicate that the function of SpHMT-1 in Cd detoxification does not depend on PCs only, and suggest that SpHMT-1 may sequester cytosolic GSH-Cd complexes into the vacuole.

Pasting Properties and Gel Strength of Non-Waxy Rice Flours Prepared by Heat-Moisture Treatment (수분-열처리로 제조한 멥쌀가루의 호화 특성과 겔 강도)

  • Seo, Hye-In;Kim, Chang-Soon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.2
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    • pp.196-204
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    • 2011
  • Heat-moisture treatment (HMT) was applied to 4 samples of rice flours, Goami (GM), Taeguk (TG), Choochung (CC) and Koshihikari (KSHK), of which amylose contents were 31.5, 32.3, 24.3, and 23.3%, respectively. Wet-milled rice flours were dried, moisture content adjusted to 21, 24, 27 and 30%, respectively, and autoclaved at 100 and $105^{\circ}C$ for 30~90 min. The changes on swelling, solubility, RVA (rapid visco analyser) paste viscosities and gel strength were observed. In GM and TG, peak viscosity (PV) and breakdown (BD) decreased and no peak appeared as moisture and treatment time increased by HMT. In CC, FV increased notably with big increase of PV and setback (SB) by HMT compared to the other rice flours. BD in all the samples decreased as moisture, temperature, and time increased by HMT. RVA pasting properties of HMT GM and HMT TG were changed remarkably under conditions of moisture 21%, $100^{\circ}C$ and 30 min whereas for HMT CC and HMT KSHK, higher temperature or more time was required at the same mois ture levels. The swelling power, solubility and gel strength increased by HMT. Gel strength correlated positively with SB (r=0.78, p<0.01) and negatively with BD (r=-0.71, p<0.01) and PV (r=-0.36, p<0.05) resulting from strengthening the structure of starch granules in rice flours by HMT.

A Study on 3 Shaft Hydromechanical Transmission Design Considering Power and Speed Characteristics (동력특성과 속도비를 고려한 3축 정유압 기계식 변속기의 설계 연구)

  • Sung, Duk-Hwan;Kim, Hyun-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.26 no.12
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    • pp.2615-2623
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    • 2002
  • In this paper, a systematic design approach for a three shaft hydromechanical transmission(HMT) system is proposed by considering the power characteristics and speed ratio range. Using network analysis, possible configurations of the 3 shaft HMT are analyzed and it is found that the influence of HSU stroke on the power distribution of the HMT can be investigated by the network analysis. In addition, design methods are presented from the viewpoint of (1) power distribution and (2) speed ratio range. From the power distribution and the speed ratio range, a HMT configuration can be constructed, which minimizes the power circulation and provides the desired speed ranges. Based on the 3 shaft HMT analyses and the proposed design approach, a 3 shaft HMT is designed which provides 4 speeds in forward and 1 speed in reverse while keeping the power circulation less than 150% of the input power. It is expected that the design method suggested in this study can be used in a systematic design of the 3 shaft HMT.

Power Circulation Characteristics of Hydro-Mechanical transmission System in Steering (정유압 기계식 변속기의 조향시 동력 순환 특성)

  • Kim, J. S.;Kim, W.;Jung, Y. H.;Jung, S. B.;Kim, H. S.
    • Transactions of the Korean Society of Automotive Engineers
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    • v.5 no.2
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    • pp.13-22
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    • 1997
  • Power flow characteristics of a hydro-mechanical transmission system(HMT) are investigated for tracked vehicle in steering. A HMT consisting of two hydrostatic pump motors(HST), several planetary gear trains and steer differential gear is considered. In order to obtain the direction and magnitude of the power flow of the HMT, network theory for the general power transmission is used. Network model for the HMT in steering is developed, which consists of shafts, nodes and transmission elements such as clutch, gear, etc. Power flow analysis procedure consists of two stages : (1) traction force analysis in steering, (2) power flow analysis in HMT. Torque and speed of every transmission element of the HMT is determined from the network analysis. Also, efficiency, mechanical and hydraulic power loss including HST, are obtained. In addition, the regenerative power flow resulting from steering can be studied in graphic display. The power flow analysis program(PCSTEER) developed in this work can be used as a useful design tool for the tracked vehicle with HMT.

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Performance Characteristics of Hydro-mechanical Transmission and Design Parameters for Type Selection (정유압-기계식 변속기의 성능 특성과 형식 선정을 위한 설계 변수)

  • Sim, Dong-Guk;Kim, Kyeong-Uk;Han, Jung-Soo
    • Journal of Biosystems Engineering
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    • v.36 no.6
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    • pp.422-433
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    • 2011
  • Market demand for hydro-mechanical transmission (HMT) for agricultural tractors has increased recently. To select a type of HMT satisfying design conditions, performance characteristics of 12 HMT types must be understood. This study was conducted to provide tractor engineers with a guideline to select the most appropriate HMT type for their design requirements. Characteristics on speed reduction ratio, power transmission efficiency, power regeneration, lock-up angular velocity, output torque ratio and torque ratio of planetary gear train axis of the 12 HMT types were investigated and presented as either formula or graphical forms. A guideline to select proper HMT type was also presented using 2 parameter: lock-up angular velocity (${\omega}_L$) and torque ratio of the planetary gear train axis. In addition, effect of gear ratio of the planetary gear train on the power transmission efficiency was investigated and a guideline to select the best gear ratio was also presented.

Effects of Hubakmawhang-tang on Asthma Model Mice Induced by Ovalbumin (후박마황탕(厚朴麻黃湯)이 ovalbumin으로 유도된 천식 모델 생쥐에 미치는 영향)

  • Na, Ga-young;Lee, Hye-in;Kim, Young-kwang;Moon, Young-ho
    • The Journal of Internal Korean Medicine
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    • v.39 no.4
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    • pp.451-462
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    • 2018
  • Hubakmawhang-tang (HMT), listed in Geumgweyoryak, is an oriental medicine used for the symptoms of asthma, such as cough and dyspnea. In this study, we investigated the HMT effects on ovalbumin-induced asthmatic in mice. We examined weight changes, airway hyperresponsiveness, histopathological abnormalities, immune cell infiltrations, immunoglobulin and inflammatory cytokine levels, and spleen body weight ratios in asthmatic mice. HMT inhibited airway hyperresponsiveness, immune cell infiltration, and airway remodeling and caused a significant lowering of serum IgE and IgG1 levels. The asthmatic mice had elevated IL-4 levels in lung tissue and this elevation was effectively prevented by HMT. HMT did not cause changes in body weight or in the spleen body weight ratio. Therefore, HMT might have an anti-asthmatic effect in the ovalbumin-induced mouse model.

Texture segmentation using Neural Networks and multi-scale Bayesian image segmentation technique (신경회로망과 다중스케일 Bayesian 영상 분할 기법을 이용한 결 분할)

  • Kim Tae-Hyung;Eom Il-Kyu;Kim Yoo-Shin
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.4 s.304
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    • pp.39-48
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    • 2005
  • This paper proposes novel texture segmentation method using Bayesian estimation method and neural networks. We use multi-scale wavelet coefficients and the context information of neighboring wavelets coefficients as the input of networks. The output of neural networks is modeled as a posterior probability. The context information is obtained by HMT(Hidden Markov Tree) model. This proposed segmentation method shows better performance than ML(Maximum Likelihood) segmentation using HMT model. And post-processed texture segmentation results as using multi-scale Bayesian image segmentation technique called HMTseg in each segmentation by HMT and the proposed method also show that the proposed method is superior to the method using HMT.

Effect of Hexa-methylenetetramine (HMT) on Nucleation and Growth Behaviors of Ni(OH)2 Nanosheets Produced by Electrodeposition (전착법으로 제작한 Ni(OH)2 나노 시트의 핵 형성과 성장 거동에 미치는 헥사-메틸렌테트라민(HMT)의 영향)

  • Kim, Dong Yeon;Son, Injoon;Choi, Mun-Hyun
    • Journal of Surface Science and Engineering
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    • v.54 no.1
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    • pp.37-42
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    • 2021
  • Electrodeposition is a synthetic method that allows fine control of the nucleation and growth factors of metals and is a suitable method for studying the nucleation and growth of Ni(OH)2. Hexa-methylenetetramine (HMT) helps to form Ni(OH)2 nanosheets by increasing the OH- of the nickel precursor solution and helps to improve the electrochemical properties of the electrode. In this study, the structural properties of Ni(OH)2 nanosheets according to the HMT concentration change using electrodeposition were studied. As the concentration of HMT increased, the size and thickness of the Ni(OH)2 nanosheet adsorbed on the surface increased and porosity increased. Also, the Scharifker-Hills nucleation theory model and experimental data were compared. In conclusion, the nanosheet shape of the HMT 7.5 mM sample electrodeposited with -0.85 V vs. Ag/AgCl grew most uniformly, and the best result was obtained as an electrode material for a pseudocapacitor.

Distortion invariant pattern recognition using Modified synthetic HMT (수정 합성 HMT를 이용한 왜곡불변 패턴 인식)

  • 현영길;김종찬;김정우;도양회;김수중
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.24 no.7B
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    • pp.1361-1369
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    • 1999
  • A hit-miss transform(HMT) using modified synthetic structuring elements(SEs) for distortion-invariant recognition of multiple objects is proposed. A fundamental problem in an HMT is the determination of the optimal SE needed to improve the false alarm rate, and detect distorted objects with various shapes. The proposed synthetic methods of SE provide good solutions against this problem. One is the multistage synthesis of each true class SE using only set theory, and the other is the multistage synthesis of each true class and false class SE using set theory and SDF(synthetic discriminant function) synthesis method. Simulation results show the proposed methods can be used for the recognition of distorted intraclass objects and the discrimination of similar interclass objects.

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Power Transmission Characteristics of a Hydro-Mechanical Transmission (정유압 기계식 변속장치의 동력전달특성)

  • Seong, Deok-Hwan;Kim, Hyeong-Ui;Lee, Geun-Ho;Kim, Hyeon-Su
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.25 no.11
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    • pp.1854-1862
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    • 2001
  • In this paper, power flow characteristics of a hydromechanical transmission(HMT) are investigated using network analysis. The HMT used in this study consist of a hydrostatic unit(HSU), planetary gear sets, clutches and brakes providing forward 4 speeds and backward 2 speeds. Since the HMT power flows showing a closed loop and the HSU efficiency varies depending on the pressure and speed, a systematic approach is required to analyze the power transmission characteristics of the HMT. In order to analyze the closed loop power flow and the HSU power loss which changes depending on the pressure and speed, network model is constructed fur each speed range. In addition, an algorithm is proposed to calculate an accurate HSU loss corresponding to the experimental results. It is found from the network analysis that the torque and speed of each transmission element including the HSU can be obtained as well as direction of the power flow by the proposed algorithm. It is expected that the network analysis can be used in the design of relatively complicated transmission system such as HMT.