• 기본간호학회지
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• 제6권3호
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• pp.544-558
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• 1999

With the increasing incidence of AIDS, it is probably inevitable that nurses working in hospital and community settings will come in contact with patients with AIDS. Nurses, more than any other health care profession, are on the front line of AIDS patient care. The purposes of this descriptive study were to gather information about registered nurses' knowledge and attitude regarding AIDS. and to provide a basis for the development of continuining education programs for the nurse. Data was gathered in 1988 using self-administered questionnaires given to a convinience sample of two hundred seventy registered nurses from two university hospitals, school nurses and postgraduate students of nursing. Data was analyzed with SAS. The results were as follows. Above 90% of the nurse knew well about definition of AIDS and routes of transmission but nurses relatively lacked knowledge about transmission of HIV in breast milk(69.3%). Less than half knew that drug abuser(44.1%) and sexual partner with IV drug abuser(39.6%) are at high risk for contracting AIDS. Above 70% of the nurse showed reluctance to provide care for surgery. delivery of child birth and hemodialysis of patients with AIDS. The results showed that, given a choice. 41.7% of the nurse would refuse to care for AIDS patients and 48.3% claimed that they should have a right refuse to care for AIDS patients. Reluctance of nursing patient with AIDS appeared to be principally associated with general fear of becoming infected with HIV. 41.8% exhibited a sympathetic attitude toward individual AIDS patient. The study findings suggest that it is necessary to examine the correlations between knowledge and attitude and to develop continuing education programs that alleviate the fear of contagion of the nurse.

• Journal of Trauma and Injury
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• 제28권1호
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• pp.9-14
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• 2015

Purpose: The aim of this study was to estimate the seropositive prevalence of blood-borne infection in neurotrauma patients who underwent emergent surgical intervention, especially patients with hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and human immunodefIciency virus (HIV). Methods: A retrospective review identified 559 patients with traumatic brain injury and spinal trauma who underwent emergent surgery between 2007 and 2014. We reviewed the medical records and extracted data, including age, sex, location of lesion, result of serologic tests, time interval of admission and surgery after presenting to emergency room. Serologic tests for HBV, HCV, syphilis and HIV were performed and analyzed to determine whether the seropositive results were confirmed by the surgeon before surgery. Results: The majority of the patients were male (74.6%), and the mean age was $55.4{\pm}20.2years$. Most patients underwent surgery due to traumatic brain injury (90.0%). Fifty-three patients (10.0%) showed a positive result on at least one serologic test. Seropositive rates according to pathogens were 0.5% for syphilis, 5.2% for HBV and 3.9% for HCV. No positive results were noted on the serologic tests for HIV. HBV in patients with spinal cord injury and age from 40 to 49 years were associated with high serologic positive rate, and that result was statistically significant. However, no statistically significant differences were found in the other variables. Serologic results could not confirmed before surgery in the majority of the cases (62.1%), and 10.4% of these patients showed seropositive results. Conclusion: The results of this study emphasize the importance of taking precautions and conducting rapid serologic testing in preventing the occupational transmission of blood-borne viruses to health-care workers.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제29권3호
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• pp.262-267
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• 2007

Implantation of allografts has increased widely with not only the availability of many allogenic bone but also allogenic soft tissues. The aim of tissue banking is to provide surgeons with safe tissues compatible with their intended clinical application. The incidence of tissue transplant-transmitted infection is unknown and can only be inferred from prospective studies. The possibility of donor-to-recipient disease transmission through soft tissue transplantation can be considered by reviewing the risk associated with other transplanted hard tissues. Viral, bacterial, and fungal infections have been transmitted via transplantation of soft tissue allografts such as skin, cornea, dura, pericardium. fascia lata, and heart valves. Corneas have transmitted rabies, Creutzfeldt-Jakob disease (CJD), hepatitis B (HBV), cytomegalovirus (CMV), herpes simplex virus (HSV), bacteria, and fungi. Heart valves have been implicated in transmitting tuberculosis, hepatitis B. HIV-1 and CMV. CJD has been transmitted by dura and pericardium transplants. Skin has transmitted CMV, bacteria, and fungi. Cadaveric skin, pericardium, dura, and fascia lata have been used in dental patients with intra-oral soft tissue injuries and GBR. This study is review of the considering transmission of infectious disease in allogenic soft tissues and guidelines of reducing the risk. Prior to use, many tissues are exposed to antibiotics, disinfectants, and sterilants, which further reduce or remove the risk of transmitted disease. Because some soft tissue grafts cannot be subjected to sterilization steps, the risk of infectious disease transmission remains and thorough donor screening and testing is especially important.

• 보건교육건강증진학회지
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• 제14권2호
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• pp.125-147
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• 1997

This study was conducted in order to identify the extent to which Health Belief Model (HBM) constructs explain the likelihood of taking preventive behaviors for AIDS among the young adolescents in Korea. HBM was applied as the theoretical framework for developing questionnaire items in this study. The survey instrument included all of the constructs of Health Belief Model, namely, perceived susceptibility, perceived severity, perceived benefit, perceived barriers, cue to actions for preventive behaviors concerning AIDS. Additionally, demographic characteristics of the respondents, their sexual experiences, and AIDS Knowledge Test were included in the study. Each of HBM constructs were developed with a 5-point Likert type scale from l(never agree) to 5 (absolutely agree). The survey was conducted with a total of 247 military men in a city on September 18, 1996, using self-reported questionnaire. The results of the study were summarized as follows: 1. Because the subjects for this study were military soldiers, their demographic characteristics were limited to all men, young age, and ummarried. Educational status was evenly distributed between high school graduates and university students. 2. On the average, the respondents started their first sexual relationship at 18 years old and 82.6% of them did not use condom when having their first sexual experience. Thirty-one percent of the subjects had sexual contact with prostitutes and the average number of sexual contact with prostitutes was 5 times during the past 2 years. 3. The results of AIDS Knowledge Test scores demonstrated that the respondents had a high level of knowledge about AIDS. However, some misconceptions about transmission of AIDS through casual contact were still prevailed. Sixty-six percent of the respondents expressed that people infected with HIV should be isolated from the society in order to protect the general public. 4. All the respondents expressed that they had heard about AIDS before. TV was found to be the source which provided information on AIDS most frequently. 5. Among fundamental constructs of Health Belief Model, scores of perceived benefit of taking preventive action against AIDS marked the highest score, while scores of perceived susceptibility were the lowest. As a result of Multiple Stepwise Regression analysis, 13 variable groups were found to predict the preventive action by 25%. Among them, only perceived benefit variables was the most significant factor to explain preventive behaviors by 17%.

• Tuberculosis and Respiratory Diseases
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• 제68권6호
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• pp.328-333
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• 2010

Background: There are several active tuberculosis (TB) cases in Korean high schools each school year. The risk of transmission in schools is extremely high due to the considerable time spent in closed classrooms. We evaluated the control of latent tuberculosis infection in Korean high schools. Methods: When a student was identified with active TB, tuberculin skin testing was performed on their classmates and on students in their same school grade. When a student had a positive tuberculin skin tests (TST), they underwent follow-up testing with QuantiFERON-TB Gold In-Tube (QFT). The manufacturer recommended a cut-off of 0.35 IU/mL to determine QFT positivity was applied. Results: A total of 131 pulmonary tuberculosis (TB) patients were included based on the criteria for screening TB contacts in the National Tuberculosis Control Program. Seventy-five (57.2%) students tested smear positive. TST were performed on 7,109 students who were classmates of, or in the same grade as, a TB patient. Of the contacts, 1,231 students (17.3%) were TST positive and they were screened with QFT. Six hundred-sixty-six (55.0%) of the tested students returned a positive QFT result and the rate of positivity was significantly associated with the increasing size of TST indurations (p<0.0001). Conclusion: The use of QFT resulted in approximately 45% of TST positive students not being given chemoprophylaxis.

• 한국응급구조학회지
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• 제10권2호
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• pp.63-76
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• 2006

This study was designed to get basic data about AIDS educational program development of students of university, especially for students of the department of Emergecy Medical Technology. The objective of this study was to identify the level of AIDS related Knowledge and Attitude of freshmen of university. The subject for this study consisted of 2022 male and female students who entered in 2005to Gongju National university in Chungnam province. Data was colledted by self-reporting questionaire consist of 66 items on 20th, February, 2005. The findings of this study can be summarized as follows. 1) The mean overall knowledge score was estimated to be 70.22%. 2) The knowledge score about definition of AIDS was high(93.2%). but knowledge score about progression and incubation period was low(48%). 3) AIDS related knowledge about diagnosis with blood was was high(91.2%), but those about period of antibody formation was relatively low(66.2%). 4) The score about latent appearance of AIDS-related symptoms was hlgh(93.7%), but those of apprehension of individual symptom was very low(57.5%). 5) Percentage of correctly answered respondent about transmission with needle and transfusion was very high(>94%), but the score of transmission through the anal and oral sex was relatively low(75-79%). 6) The knowledge score about prevention with condom was high(89.5%), but misconception of disinfection and vaccination was also high. 7) Acknowledgement about utility of consultation, information, treatment was very low (10-17%). In the end, the study concludes that it is necessary to develop comprehensive AIDS education programs to improve knowledge about the disease as well as to allay the fears and anxiety of the contact.

• Journal of Preventive Medicine and Public Health
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• 제57권1호
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• pp.8-17
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• 2024

Objectives: The effectiveness and efficiency of pre-exposure prophylaxis (PrEP) in reducing the transmission of human immunodeficiency virus (HIV) among men who have sex with men (MSM) relies on how widely it is adopted and adhered to, particularly among high-risk groups of MSM. The meta-analysis aimed to collect and analyze existing evidence on various factors related to PrEP adherence in MSM, including demographic characteristics, sexual behaviors, substance use, and psychosocial factors. Methods: The meta-analysis followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The search included articles published between January 2018 and December 2022, obtained from the PubMed, ScienceDirect, and Scopus databases. The studies that were included in the analysis reported the proportion of MSM who demonstrated adherence to PrEP and underwent quality appraisal using the Newcastle-Ottawa Scale. Results: Of the 268 studies initially identified, only 12 met the inclusion criteria and were included in the final meta-analysis. The findings indicated that education (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.12 to 2.40), number of sexual partners (OR, 1.16; 95% CI, 1.02 to 1.31), engaging in sexual activities with an human immunodeficiency virus-positive partner (OR, 1.59; 95% CI, 1.16 to 2.26), substance use (OR, 0.83; 95% CI, 0.70 to 0.99), and lower levels of depression (OR, 0.55; 95% CI, 0.37 to 0.82) were associated with higher rates of PrEP adherence among MSM. Conclusions: Despite these findings, further research is necessary to investigate PrEP adherence more comprehensively. The findings of this meta-analysis can be utilized to inform interventions aimed at improving PrEP adherence among MSM and provide directions for future research in this area.

• 한국보건간호학회지
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• 제13권1호
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• pp.63-76
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• 1999

The purpose of this study was to provide the basic data for developing a program for effective health education about AIDS (Acquired Immunodeficiency Syndrome) by investigating the knowledge and attitudes of middle and high school students about AIDS. The subjects were 476 middle school students and 658 high school students from Seoul and Kang Won province. The data were collected from November 19 to December 18. 1996. using a 56-item questionnaire. and analyzed by SAS program for t-test. x2-test. and pearson correlation coefficients. The results were as follows : 1. High school students had more knowledge than middle school students about AIDS. 2. Male. students from Seoul. and students who had drinking experience and smoking experience among middle school students. and male. students from Seoul. and students of non-coeducation among high school students were more knowledgeable about AIDS. 3. Misconceptions about the transmission of AIDS through non-intimate contact were especially common among middle school students. And a high proportion of middle and high school students knew very little about the symptoms of AIDS. 4. High school students had more positive attitudes toward AIDS than middle school students. 5. Students from Seoul and students who had smoking experience among middle school students. and students from Seoul and non-coeducation and students who had substance use experience among high school students were more positive attitudes about AIDS. 6. Most of the middle and high school students agreed that there is a need for AIDS education. 7. Middle and high school students reported that had learned about AIDS mostly from TV. Since students in the middle-school age group are especially at risk for developing AIDS­related behaviors. this study findings suggest that it is crucial to develop school-based AIDS education programs that help students acquire the knowledge and attitudes to adopt and maintain behaviors that reduce the risk of HIV (Human Immunodeficiency Virus) infection and other related health problems.

• 보건교육건강증진학회지
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• 제11권1호
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• pp.43-56
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• 1994

Although the officially confirmed incidence of the acquired immune deficiency syndrome(AIDS) has remained low thus far in Korea, the progression of the pandemic has been rapid, concerned about an eventual increase in transmission. Until a vaccine or cure is found, public information and education remain an important weapon against AIDS. For the year 2000, the current WHO projection is that there will be a cumulative total of 40 million HIV infections in man, woman and children, of which more than 90％ will be in the developing countries. The incerased mortality among adults and children has raised concerns that AIDS may become so devastaing as to reverse positive population growth rates and wipe out entire population. In order to plan for the rising incidence of patient with AIDS, an assessment of AIDS-related cognition and behavior, attitude of the recognized high-risk groups is necessary. Considering that undergraduates have sexuality active and more oriented toward sexual concerns than other ages. Adolescents today are more sexually involved than in the past: The media, including films, music, and television, reinforce sexual concerns by preseating images of highly sexual adolescents. Incidence of both petting and sexual intercourse in higher and occurs at earlier ages, they are important reservoir of AIDS infection. Hence, it has become important to emymerats and describe the knowledge, attitude and behavior of them, I want.. This information will eventually guide the direction of change in public policies and education programs to meet the challenges of AIDS. The objective of this study were to identity Knowledge, Attitude, Experience of Sex and AIDS in Korea. The data were collected by survey at Korean Federation for AIDS Affairs, INC. and J university, K junior college. After October in 1993, surveyed with 507 student during their's college days in Seoul. The questionnaire was designed to provide information on sex and AIDS-related knowledge and attitudes and experience. AIDS-related knowledge was measured by using 26 questions on mode of transmission and AIDS-related attitudes were measured by 7 questions, AIDS-related experience was measured by 5 questions. There were the main dependent variables in our study, In conclusion, students during their university day need to develop AIDS-preventive education programs. Clearly, the many AIDS-prevention educational effort need to be guided by well trained health agents. Financial supports from all sectors (i.e., public and private) of our society are required to achieve that end. Further researches on AIDS-related Knowledge and Attitude and behaviors of undergraduates are needed for the development of comprehensive AIDS prevention programs.

• 생명과학회지
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• 제26권10호
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• pp.1196-1201
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• 2016

연꽃의 자방으로부터 80% MeOH로 추출하고, 얻어진 추출물을 n-hexane, ethyl acetate, n-butanol 및 H₂O으로 용매 분획하였다. 이 중 n-hexane 분획물에 대해 silica gel과 octadecyl silica gel column chromatography 및 Prep-HPLC system을 반복 수행하여 5 종의 물질을 분리 하였다. 각 화합물의 화학구조는 NMR, GC/MS및 ESI/MS 등의 분광학적 스펙트럼을 측정하고, 해석하여 1-eicosanol (1), cycloartenol (2), trans-squalene (3), pentadecanoic acid (4) 및 β-sitosterol (5)으로 동정하였다. 이 화합물들은 연꽃 자방추출물에서 처음으로 분리하고 동정하였으며 앞으로 이 화합물들에 대한 다양한 생리적 및 약리적 활성을 검토함으로써 건강기능성 식품 또는 의약품의 소재로서의 충분한 가치가 있다고 여겨진다.