• Parasites, Hosts and Diseases
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• v.46 no.2
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• pp.71-75
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• 2008

The diagnosis of cryptosporidiosis has been carried out using coprologic techniques in the Republic of Korea. However, antibody responses to Cryptosporidium have rarely been studied. Serum antibodies from HIV-positive/oocyst-positive Korean patients recognized significantly 31 and 27 kDa antigens, and HIV-negative/oocyst-positive individuals clearly reacted to 15/17 kDa antigens. Compared with oocyst-positive cases, 18.7% and 75.8% of sera from HIV-positive patients reacted to 31 and 27 kDa antigens. Only 11.1% of HIV-negative individuals reacted to 15/17 kDa. Based on these findings, serum antibody responses were different between HIV-positive and HIV-negative individuals infected with Cryptosporidium, and it is suggested that HIV-positive patients are more frequently exposed to C. parvum compared to HIV-negative individuals.

• Korean Journal of Audiology
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• v.25 no.1
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• pp.36-42
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• 2021

Background and Objectives: Globally, the human immunodeficiency virus (HIV) is responsible for one of the most serious pandemics to date. The vulnerability of the vestibular system in individuals with HIV has been confirmed, and central vestibular impairments have been frequently reported. However, there are disagreements on the impact of HIV on peripheral vestibular function. Thus, the current study aimed to determine the prevalence of peripheral vestibular impairment, specifically related to the semi-circular canals (SCCs), in HIV-positive individuals receiving antiretroviral (ARV) treatment. Subjects and Methods: A total of 92 adults between the ages of 18 and 50 years (divided into two groups) participated in the study. The first group comprised HIV-positive individuals receiving ARV treatment (n₁=60), and the second group comprised HIV-negative participants (n₂=32). The video head impulse test was used to conduct the head impulse paradigm (HIMP). Results: Bilateral normal HIMP results were obtained in 95% of the HIV-positive participants and all HIV-negative participants. The gain of the left posterior SCCs was significantly lower in the HIV-positive group, while the gains of all other canals between the two groups were comparable. Conclusions: The prevalence of peripheral vestibular impairment in the HIV-positive group was not significantly different from that of the HIV-negative group. The reduced prevalence in the current study may be attributed to participant characteristics, the test battery employed, and the central compensation of the vestibular dysfunctions at the later stages of infection.

• Journal of Audiology & Otology
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• v.25 no.1
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• pp.36-42
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• 2021

Background and Objectives: Globally, the human immunodeficiency virus (HIV) is responsible for one of the most serious pandemics to date. The vulnerability of the vestibular system in individuals with HIV has been confirmed, and central vestibular impairments have been frequently reported. However, there are disagreements on the impact of HIV on peripheral vestibular function. Thus, the current study aimed to determine the prevalence of peripheral vestibular impairment, specifically related to the semi-circular canals (SCCs), in HIV-positive individuals receiving antiretroviral (ARV) treatment. Subjects and Methods: A total of 92 adults between the ages of 18 and 50 years (divided into two groups) participated in the study. The first group comprised HIV-positive individuals receiving ARV treatment (n₁=60), and the second group comprised HIV-negative participants (n₂=32). The video head impulse test was used to conduct the head impulse paradigm (HIMP). Results: Bilateral normal HIMP results were obtained in 95% of the HIV-positive participants and all HIV-negative participants. The gain of the left posterior SCCs was significantly lower in the HIV-positive group, while the gains of all other canals between the two groups were comparable. Conclusions: The prevalence of peripheral vestibular impairment in the HIV-positive group was not significantly different from that of the HIV-negative group. The reduced prevalence in the current study may be attributed to participant characteristics, the test battery employed, and the central compensation of the vestibular dysfunctions at the later stages of infection.

• Journal of Korean Academic Society of Home Health Care Nursing
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• v.24 no.2
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• pp.142-150
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• 2017

Purpose: The purpose of this study was to examine the relationships of attitudes, stigma, and moral sensitivity of nurses toward HIV/AIDS. Methods: The participants were 530 nurses working in general hospitals in South Korea. A structured questionnaire regarding attitudes, stigma toward HIV/AIDS, and moral sensitivity was used. The data were analyzed using t-tests, ANOVAs, and Pearson correlation coefficients. Results: Nurses' attitudes toward HIV/AIDS differed by job position; nurses' moral sensitivity toward HIV/AIDS differed by age, marital status, education level, clinical practice career, and job position; and nurses' stigma toward HIV/AIDS differed by age, clinical practice career, subjective economic status, HIV/AIDS education experience, and HIV/AIDS patient care experience. Attitudes of nurses toward HIV/AIDS were more negative when stigma toward HIV/AIDS was higher (r=-0.58, p<.001), these attitudes were not correlated with moral sensitivity. Conclusions: The attitudes of nurses toward HIV/AIDS were more negative when stigma toward HIV was higher, and these attitudes were not correlated with moral sensitivity. Therefore, nurses should be provided education that takes their age, marital status, clinical practice career, and experiences in HIV-related education and caregiving into account.

• Korean Journal of Social Welfare Studies
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• v.44 no.3
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• pp.347-369
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• 2013

Quality of life for people living with HIV/AIDS is significant as it concerns the treatment process, survival rate, HIV/AIDS prevention and treatment as well. Prevalent prejudice in our society significantly lowers the quality of patient's life. There is a need for an intervention and the effort to eliminate the stigma in order to lessen the negative effects as well. However, there are very few researches that examine the quality of life when it comes to people living with HIV/AIDS; even less when it comes to research that examines the stigma that affects the quality of life negatively. Therefore, this research seeks to verify the moderating effects of social support that seek to eliminate the stigma upon the quality of life in people living with HIV/AIDS. Research had been conducted with 102 people living with HIV/AIDS and the balancing effect of the social effort was verified through hierarchical regression analysis and a simple slope test. As the result of the research, control variables such as educational level and whether the patient has a job or not have significant effect and the stigma that the patient is aware of has significant negative effect. Social support had positive effect in quality of life and that it has a moderating effect on stigma which in turn affects the quality of life. Based on these results, social work related implications that were suggested are as follows; need for information and education as to better the quality of life for people living with HIV/AIDS and eliminate the social stigma and that group support program based on the local community which is needed for social support. Further research was advised based on the limitations of this research.

• The Journal of the Korea Contents Association
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• v.16 no.8
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• pp.247-256
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• 2016

The purpose of this study was to identify the mediating effect of hope relationships among social support, social stigma and quality of life. It was conducted to measure social support, social stigma, hope and quality of life from 197 HIV-infected people. Data collection was carried out through one-on-one interviews by counselling nurse. The mediating effect was analyzed through Structure Equation Model using AMOS 21.0 program and indirect effect was analyzed by bootstrapping method. As a result of analysis, first, social support had a significant positive effect on quality of life. But social stigma had a significant negative effect on quality of life. Second, social support had a significant positive effect on hope. But social stigma had a significant negative effect on hope. Third, hope had significant mediating effect within the influence of social support and social stigma on quality of life. It is suggested to develop and apply comprehensive intervention program for improve quality of life of HIV infected people in community.

• Journal of Convergence for Information Technology
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• v.10 no.8
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• pp.108-119
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• 2020

This describes the level of knowledge and attitudes about HIV and their related factors among Cambodian adolescents. A cross-sectional design was used to examine the knowledge and attitude of 463 Cambodian high school students using HIV-KQ-18 (HIV-Knowledge Questionnaire-18) and HIV/AIDS Behavior Surveillance Survey Index (measuring attitude about HIV). The majority of the adolescents had a relatively low level of overall HIV knowledge (6.70 ± 3.66 (range: 0-16)) and held a very negative attitude (1.92 ± 0.87 points (range: 0-4)) toward the disease. Using multiple regression analysis, being male (β = 0.28, p < 0.001) and using YouTube as a social network service (β = 0.33, p = 0.035) were found to be independent factors associated with higher level of HIV knowledge. Study findings suggest the importance of informing policymakers and school nurses about the need to develop a and require a culturally sensitive specific health education program on HIV for Cambodian adolescents.

• Research in Community and Public Health Nursing
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• v.29 no.3
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• pp.279-289
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• 2018

Purpose: This study has been conducted to identify factors that influence the initiation of treatment after the diagnosis of Korean patients with HIV. Methods: A cross-sectional study design was used, and 290 patients with HIV from outpatient departments of 7 hospitals participated. Self-report questionnaires included items on the days from the primary diagnosis to the initiation of treatment, and the patients' demographic and disease related characteristics. Negative binomial regression model (NBR) was utilized to determine risk factors influencing the initiation of treatment after the diagnosis of the patients with HIV. Results: The skewness of days was 6.62, and the degree of asymmetry of distribution was severe. In NBR, patients who were in their 40s and 50s, female, unmarried and living with their family, jobless, in a middle or high level of economic status, and diagnosed before 2014 showed a higher risk of delayed treatment than patients who were younger, male, married and living with family, in a low level of economic status, and diagnosed in 2014 or afterwards. Conclusion: The findings suggest the necessity of intervention to promote HIV patients' early entry into treatment based on the participants' characteristics.

• The Korean Journal of Cytopathology
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• v.16 no.1
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• pp.47-51
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• 2005

Plasmablastic lymphoma (PBL) is a recently described aggressive B-cell neoplasm, which usually manifests as a localized disease of the oral mucosa in individuals infected with human immunodeficiency virus (HIV). Recently we encountered a case of plasmablastic lymphoma manifesting in the left maxillary sinus and cervical lymph node of a previously healthy HIV-negative man, 48 years of age. we conducted a fine-needle aspiration smear of the cervical lymph node, and this was found to be highly cellular with numerous large cells exhibiting eccentrically positioned nuclei, prominent nucleoli, and moderate quantities of basophilic cytoplasm. A biopsy of the mass in the maxillary sinus evidenced diffuse growth of similar plasmablastic cells. These tumor cells were negative for the leukocyte common antigens, CD20, CD3, CD30, and EMA. However, the cells tested positive for CD79a and CD138/syndecan-1. The tumor cells also exhibited L-light-chain restriction. The Ki-67 proliferation index was measured at almost 100%. The patient was diagnosed with plasmablastic lymphoma. After three cycles of combination chemotherapy and radiotherapy, the patient went into complete remission, and currently remains in this state.

• Journal of Digital Convergence
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• v.13 no.11
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• pp.255-265
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• 2015

This study was done to identify the levels of knowledge and attitude toward HIV/AIDS in professional graduate medical school students. A cross-sectional survey was used, and data were collected in 2014. Participants were 97 students in South Korea. Data were analyzed using SPSS WIN 19.0 program. The mean score for HIV/AIDS knowledge was 8.91 and attitude was 7.00 out of 15. The levels of HIV/AIDS knowledge and attitude were not statistically significantly different according to participants' general characteristics. There was a statistically significant correlation between the levels of HIV/AIDS knowledge and attitude. Medical students having a high HIV/AIDS knowledge level tended more towards a positive attitude. These findings can be used in developing effective education strategies for medical students and health care providers to increase knowledge and decrease negative attitude toward HIV/AIDS.