• 제목/요약/키워드: HER2/4

검색결과 1,114건 처리시간 0.032초

뇌졸중 이후의 교합관계의 변화 증례 (CHANGES OF DENTAL OCCLUSION AFTER STROKE: CASE REPORT)

  • 이성종;이은영;김혜정;황지영;이제호
    • 대한장애인치과학회지
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    • 제4권1호
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    • pp.26-31
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    • 2008
  • Cerebrovascular Accident(stroke) is that a sudden, nonconvulsive loss of neurologic function due to an ischemic or hemorrhagic intracranial vascular event. If stroke happens at the portion of trigeminal motor nucleus or its control part of cerebral cortex, masticatory muscles will be atrophy or paralyzed. So it is possible that dental occlusion changes after stroke. A 74-aged woman recurred mild stroke 2 month ago, who had experienced severe stroke 2 years ago. After recurrence, suddenly her upper full denture was dropped when lower denture contacted upper one. According to the her occlusion exam, her lower jaw moved back slightly compared with the occlusion of old denture. And her face had asymmetry and lower jaw dislocated to paralyzed side. A 50-aged man was treated because many cervical caries, which would occur because of an aftereffect of stroke, long-herm hospitalization and limits of self oral-care. 6 years ago he had cerebral hemorrhage and he claimed that he cannot bite exactly. Just two pairs of teeth was contact on biting, his lower jaw was located back, too. This two case suggests that dental occlusion can change after stroke.

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약물유발성 간염으로 진단된 소음인(少陰人) 황달(黃疸) 환자 치험 1례 (A Case Study of Soeumin Jaundice Patient Diagnosed as Drug-Induced Hepatitis)

  • 이갑수;최경주;이태규;고병희;송일병;이수경
    • 사상체질의학회지
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    • 제17권2호
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    • pp.99-106
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    • 2005
  • 1. Objectives The primary purpose of this case is to report that a Soeumin patient diagnosed as drug-induced hepatitis was treated with 'K wokhyangchungki-san added Perennial artemisia' and then her symptom and liver function test results improved. 2. Methods We diagnosed her as yin-jaundice on Taeum Syndrome. So we treated her with 'Kwokhyangchungki-san added Perennial artemisia'. 3. Results After we treated het with 'K wokhyangchungki-san added Perennial artemiJia' her symptom and liver funaion test results was improved rapidly. 4. Conculusions 'Kwokhyangchungki-san added Perennial artemisia' may have an added on Treatment of Drug-induced hepatitis of Soeumin.

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관절내 유리체로 인한 관절장애 치험 1례 (A Case Study of Arthropathy of Wrist Resulting from Loose body)

  • 김경선;김현호;김은이;임은철;선영재
    • 사상체질의학회지
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    • 제16권2호
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    • pp.134-138
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    • 2004
  • 1. Objectives In general, arthropathy is treated with conservative method or only observed. Recently, I have effectively treated one patient with chronic arthropathy caused by loose body using constitutional method. So, I would like to report about this case. 2. Methods Consulting her Sungjeong(性情), Chehyungkisang(體形氣像) and QSCC II, I diagnosed her as Taeumin and treated her with Taeumjowi-tang(太陰調胃湯) plus jejo etc. 3. Results After treatment she felt her symtoms-pain, edema, stiffness of joint improved. 4. Conclusions This paper describes the process of management and changes of symptoms. I hope this paper useful to rehabilitatable treatment for arthropathy through Sasang Constitutional Medicine.

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Lymph Node Ratio Assessment of Brain Metastasis in Early Breast Cancer Cases

  • Demircioglu, Fatih;Demirci, Umut;Akmansu, Muge
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권3호
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    • pp.1665-1667
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    • 2013
  • Background: Ten to 30% of early breast cancer (EBC) patients develop brain metastasis (BM) during their follow-up. In this study, we aimed to evaluate importance of the lymph node ratio (LNR) in development of BM in EBC cases. Materials and Methods: Ninety patients whom had axillary metastases in lymph nodes at their initial diagnosis and developed BM during 5-year follow-up were detected in 950 EBC patients. LNR values were calculated for all patients and after categorization into 4 molecular sub-types as luminal A, luminal B HER-2 (+), HER-2 overexpressing and basal- like. Comparison was with control group patients who had similar characteristics. Results: In the comparison of all molecular sub-types of LNR, 54.9% and 28.4% values were found in patients with and without BM respectively (p<0.001). In the comparison of the LNR with control groups, a statistically significant differences were found with luminal A with BM (p=0.001), luminal B HER-2 (p=0.001), HER-2 overexpressing (p=0.027) and basal-like groups (p<0.001). In the evaluation of patients with BM, the highest ratio was found in the basal-like group (67.9%) and there was a statistically significant difference between this group and the others (p=0.048). Conclusions: EBC patients developing BM within 5 years follow-up had significantly higher LNRs for all molecular sub-types, especially in the basal-like group. Larger scale studies are now needed for evaluating LNR prognostic importance for EBC regarding BM development.

수소발생반응을 위한 Ni4Cr 나노 섬유 전기화학 촉매 합성 및 특성 분석 (Synthesis and Characterization of Ni4Cr Nanofiber Electrocatalyst for Hydrogen Evolution Reaction)

  • 이정훈;장명제;박유세;최승목;김양도;이규환
    • 한국표면공학회지
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    • 제50권5호
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    • pp.322-331
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    • 2017
  • Hydrogen evolution reaction(HER) was studied over $Ni_4Cr$ nanofibers(NFs) prepared by electrospinning method and oxidation/reduction heat treatment for alkaline water electrolysis. The physicochemical and electrochemical properties such as average diameter, lattice parameter, HER activity of synthesized $Ni_4Cr$ NFs could be modified by proper electrospinning process condition and reduction temperature. It was shown that $Ni_4Cr$ NFs had average diameter from 151 to 273 nm. Also, it exhibited the overpotential between 0.419 V and 0.526 V at $1mA/cm^2$ and Tafel slope of -334.75 mV to -444.55 mV per decade in 1 M KOH solution. These results indicate that $Ni_4Cr$ NFs with reduction heat treatment at $600^{\circ}C$ show thinnest diameter and highest HER activity among the other catalysts.

가정주부의 건강에 대한 지식, 태도 및 실천수준과 가족건강간의 관련성 연구 - 천안 및 부안지역을 중심으로 - (A Study of relationship between Housewives' Health KAP level and Family Health in Buan and Chunan Area.)

  • 이재은;이시백
    • 보건교육건강증진학회지
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    • 제6권2호
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    • pp.4-22
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    • 1989
  • This study aims to explore the relationship between housewives' health KAP level and the physical health of families. The data used in this study are obtained from the Last Evaluation Program of the National Note for Health surveyed in July, 1989. The respondents for this study are 770 housewives residing in Chunan and Buan. The reason why this study focus on KAP level of housewives is to find out whether a housewife as a emotional supporter contributes to the physical health of her families. A housewife gives her families emotional satisfaction insteade of economic satisfaction. So she has the most interest in family health among the members of her family. Therefore, housewife's KAP level will influence her family health. The independent variables chosen for the analysis are the general characteristic variables and KAP level. And the dependent variable is the physical health of families which excluded psychosocial one. This level of family health includes weight for family health and seriouseness of disease. The result of this study was summarized as follows. (1) KAP level was significantly correlated with variables which have mainly the socioeconomic characteristics. The variables were: area of residence, education level occupation, self assessment on wealth, and exposure to mass communication. (2) In the analysis of relationship between the general characteristic variables and family health, family health was significantly correlated with almost all variables. The variables were: Presence of the aged, Health status, Experience in disease, Self assessment on health, No. of families, Occupation, Education level, Self assessment on wealth, Concern on health, and Exposure to mass communication. (3) In the analysis of relationship between family health and KAP level, family health was not significantly correlated with KAP level but. (4) Also in the stepwise regression analysis, the general variables account for about 32.1 percent of the variance in the dependent variable, family health. The variable with the greatest explanatory power was presence of the aged. On the contrary, KAP level explain about 0.4 percent of the variance in the dependent variable. In sum, the study shows that housewives' health KAP level has relatively weak relationship with the physical health of families

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코로나 뉴노멀 시대의 과학교사 행위주체성 탐색 -COVID-19에 따른 원격 수업 2년 차 실행 사례를 중심으로- (Exploring Science Teacher Agency at the Age of the New Normal after the COVID-19 Pandemic: The Case of Second Year of Distance Learning Practice)

  • 이혜경;김희백
    • 한국과학교육학회지
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    • 제41권5호
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    • pp.415-428
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    • 2021
  • COVID-19로 인하여 도입된 원격 과학 수업은 이제 교사들에게 새로운 일상으로 받아들여진다. 이러한 상황에서 교사가 지난해의 실행을 습관적으로 되풀이하기보다는 변화하는 맥락을 적극적으로 해석하고, 맥락에 적절한 학습 환경을 조성하는 것이 요구된다. 본 연구에서는 COVID-19로 인하여 시행된 원격 수업 2년 차 상황에서 교사가 문제를 인식하고, 이를 해결하는 실행에서 드러나는 교사 행위주체성과 이때의 맥락을 분석하였다. 특히, 2020년 4월에서부터 2021년 7월까지 16개월 동안 교사의 원격 과학 수업 실행을 추적하여 맥락에 따라 변화하는 교사의 행위주체성을 탐색하였다. 이를 위하여 중등학교 과학교사 3인을 대상으로 질적 사례 연구를 진행하였다. 연구 참여자와의 인터뷰, 연구 참여자가 사용한 교육자료를 수집하고, 이를 지속해서 검토하며 분석하였다. 연구 결과, 교사는 스스로 자신의 수업을 비판적으로 성찰함으로써 자신의 원격 과학 수업 실행에서의 문제를 인식하고 이를 해결하기 위한 행위주체성을 발현하거나 외부로부터의 변화에 능동적으로 적응하기 위하여 행위주체성을 발현하거나 자신이 추구하는 과학 교육을 원격 수업 상황에서도 구현하기 위하여 행위주체성을 발현하였다. 그리고 이 과정에서 지난해 원격 과학 수업을 실행한 경험 및 이로부터 축적된 실천적 지식, 자신의 실행에 대한 성찰, 원격 과학 수업에 대한 장·단기적 목표가 영향을 미쳤다. 또한, 교사가 속한 맥락에서 원격 수업의 질 제고를 추구하는 학교 공동체의 분위기나 교사 사이의 활발한 소통과 협력 역시 교사 행위주체성 발현을 촉진하였다. 본 연구는 우리나라 원격 과학 수업 상황에서 어떠한 과학교사 행위주체성이 발현되었는지 탐색하였으며, 이 과정에서 영향을 미친 맥락을 분석하였다. 또한, 같은 교사가 상황이 변화함에 따라 행위 주체성 발현에 어떠한 변화가 나타나는지, 그리고 그 과정에 영향을 미치는 맥락을 이해하기 위하여 교사의 개인적인 요인 및 맥락적 요인을 분석하였다. 이를 통하여 교사 행위주체성 발현을 지원할 수 있는 전략을 마련하는 데 시사점을 제시하고자 한다.

옹호개념에 관한 신생아실 간호사의 인지 내용 분석 (A Content Analysis of the Advocacy Concept Perceived by Nurses at Nursery Room)

  • 조갑출
    • Child Health Nursing Research
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    • 제2권1호
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    • pp.13-26
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    • 1996
  • This descriptive study was done to detect the possibilities of the development of the advocacy concept in nursing. The subjects consisted of 3 nurses who had agreed to participate to the study, working at nursery room in a general hospital. Data was collected from May 22 to June 13 in 1995 through tape recorded intensive-interview, and written down, then content analyzed qualitatively related to the infant advocacy. 1. Derivation fo the meaning about advocacy concept 1) The situations in need of infant advocacy were 12 categories : malpractice, overcharing, negligence, unnecessary services, and services without consent, and so on. 2) Fourteen categories of advocacy activities percived by nurses were derived from participants' statements. Protesting infant or his /her families against their counterpart, providing informations to families, cooperating with medical staffs for her patient, then calling medical staff not so as to be maleficient to her patient in its rank. 3) The expected result of advocacy activities perceived by nurses was respectively positive to her patient or families, but negative to nurse. 4) The feelings of nurses in the sitution of advocacy were expressed in to concern, comprehension, regret, powerlessness, charity, desire, and so on. 5) Nurses perceived that advocacy activities could be influenced positively by factors related to nurses' qualification and negatively by factors related to doctor's overdo and nurse's underdo. 2. Categorization of the meaning and their relationships In case of antecedental situation in need of infant advocacy, nurse perceives her patients need the advocacy to get a benefit through nurse's information, intervention speaking, building cooperations. The expected factors to influence advocacy activities perceived by nurses, are the power imbalance between medical staffs, the nurse's qualification, and the nurse's feeling from the situation. The above results suggest that the infant care situation will be recommendable field work place for concept development of advocacy with hybride model when it involves infant's families.

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국제항공운송 승무원의 일상적 노무제공지 (The Place Where the Cabin or Flight Crew of International Air Carrier Habitually Carries Out his/her Work - CJEU, 2017. 9. 14., C-168/16, C-169/16 - Sandra Nogueira and Others v. Crewlink Ltd Miguel José Moreno Osacar v. Ryanair)

  • 권창영;김선아
    • 항공우주정책ㆍ법학회지
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    • 제34권1호
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    • pp.39-77
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    • 2019
  • 국제항공운송에 종사하는 승무원은 업무의 성격상 여러 나라에서 근로를 제공하게 된다. 국제사법에 의하면 일상적 노무제공지는 국제근로계약의 준거법 결정(제28조 제2항), 국제재판관할의 결정(제28조 제3항, 제4항)에서 중요한 역할을 수행한다. 일상적 노무제공지는 국제재판관할과 준거법의 결정을 위하여 EU에서 제창된 개념으로, 국제항공법에서 항공안전을 확보할 목적으로 승무원의 피로관리를 위해 도입된 개념인 모기지(母基地)와 입법목적이 서로 달라, 일상적 노무제공지와 모기지는 같은 개념이라고 볼 수 없다. 승무원의 일상적 노무제공지를 결정하기 위해서는 (i) 승무원이 근무를 시작하고 종료하는 곳, (ii) 승무원이 업무를 수행하는 항공기가 주로 주기(駐機)된 곳, (iii) 사용자가 전달한 지시사항을 알게 되고 근무활동을 조직하는 곳, (iv) 근로계약상 승무원이 거주할 의무가 있는 곳, (v) 사용자가 제공하고 승무원이 사용할 수 있는 사무실이 있는 곳, (vi) 승무원이 업무에 부적합하거나 징계사유가 발생할 때 참석할 의무가 있는 곳 등을 종합적으로 고려하여야 한다. 그런데 위에서 열거한 사항은 모두 모기지 소재지와 동일하므로, 승무원의 일상적 노무제공지를 결정할 때 모기지를 가장 중요한 요소로 고려하는 것이 타당하다. 이와 달리 기적국을 일상적 노무제공지로 보아서는 안 된다. 대상사안에서 CJEU는 국제항공운송에 종사하는 객실승무원의 일상적 노무제공지에 관하여 최초로 판단기준을 제시하였는바, 이는 우리나라 국제사법의 모범이 되었던 브뤼셀 규정의 해석이므로, 국제항공운송 승무원에 관하여 국제사법상 일상적 노무제공지의 개념을 이해하는데 많은 도움이 될 것으로 보인다.

경부 및 흉부신경근에 동시에 발생한 대상포진 -증례 보고- (Herpes Zoster Infection Involved in Cervical and Thoracic Spinal Segment Bilaterally)

  • 한경림;곽노길;김수미;민경신;김찬;김성모
    • The Korean Journal of Pain
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    • 제12권1호
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    • pp.144-147
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    • 1999
  • A 72-year-old female patient was presented complaining of unbearable abdominal pain in the upper left quadrant at our hospital. Two weeks earlier she had developed a vesicular eruption on the right C3 dermatome and 1 week earlier she had experienced a vesicular eruption on the left T11 dermatome. Her medical history was unremarkable. She had suffered from severe abdominal pain in the upper left quadrant for 10 days and the mild pain in the right shoulder region for 20 days. The pain in the upper left quadrant had increased and was unresponsive to drugs prescribed by the local clinic. And we performed T11 root block with 0.5% lidocaine 5 ml and dexametasone 5 mg, and thoracic epidural blockade on 1st hospital day under diagnosis of herpes zoster infection. Her VAS were improved from 10 to 2 on 2nd hospital day. We performed thoracic epidural blockade with 0.5% lidocaine 6 ml. Her VAS were changed from 2 to 7 and so then we performed the thoracic epidural blockade with 0.5% lidocaine 5 ml and triamcinolone 40 mg on 3rd hospital day. On 4th hospital day, her VAS were from 7 to 1. After 4 month of our managements she was tolerable without any medications.

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