• Journal of the Korean Applied Science and Technology
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• v.34 no.4
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• pp.1025-1035
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• 2017

In this study, the hot water extract from Mulberry (Morus alba) Leaves fermented with Hericium erinaceum mycelium (MA-HE) was assessed for antioxidant activity. Radical scavenging activity of MA-HE evaluated using 2,2-diphenyl-1-picrylhydrazyl(DPPH) radical and 2,2'-azino-bis(3-ethyl-benzothiazoline-6-sulfonic acid)(ABTS) radical. MA-HE showed 63% DPPH radical scavenging activity at $500{\mu}g/mL$ and 98.27% ABTS radical scavenging activity at $250{\mu}g/mL$. MA-HE was shown to significantly inhibited DNA strand breakage induced by free radical. MA-HE also inhibited free radical-mediated human serum albumin modification. MA-HE effectively inhibited $H_2O_2$ induced cell death and significantly increased of the 8% cell survival at $100{\mu}g/mL$. MA-HE decreased intracellular reactive oxygen species (ROS) levels in $H_2O_2$-treated cells. The results suggested that MA-HE can contribute to antioxidant and protected cells from oxidative stress-induced cell injury.

• Journal of National Security and Military Science
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• s.4
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• pp.211-240
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• 2006

King Taejo, Wang Gun had succeeded in bringing order out of chaos of the Later Three Kingdoms and establishing a new unified dynasty, Koryo. Why can he gain the victory against the king of Later Baekje, GyunHwon? What is the his leadership? These are his leadership. (1) He had the peserverance. in 927 Wang Gun had broken by Gyun Hwon's army at Gong San. Nevertheless He didn't dissapoint and trained troops for battle steadily. Therefore in 930 he gained a great victory against Gyun Hwon at An Dong. (2) He use the command rights justically. (3)His soldiers are obedient to his orders involuntarily. (4) He always cooperateed with other’s commanders. (5)He efforted to gain victory without battle. (6)He had a high and great plan. (7) He took advantage of land configuration. (8) He made the enemy to fall into internal disarray. With these leadership, Wang Gun unified Later Three Kingdoms. Regarding himself as the success or to Goguryo, he pursued a policy of expansion to the north. Therefore he extended his borders to Chongchon River. At the same time he broke the chains of the bone-rank system which had shackled Shil1a's society.

• Journal of Radiation Protection and Research
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• v.22 no.2
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• pp.119-125
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• 1997

PHWR achieves high neutron economy by adopting heavy water as its moderator and coolant. On the other hand it permits much tritium generation, compared to LWR, due to the neutron capture reaction of deuterium in heavy water. Meanwhile in the reactor core, $^3He formed as the result of-decay of tritium, captures a thermal neutron and transforms to tritium again. The existing calculation models on tritium generation in PHWR neglect the contribution of $^3He$ in both moderator and coolant due to its relatively low solubility. However the neutron capture cross-section of $^3He$ is almost $1.6{\times}10^7$ times as large as that of deuterium. That means that the dissolved amount of 0.03 ppm of $^3He$ in heavy water is enough to generate the same amount of tritium as that generated by the deuterium of total heavy water in the system. This study dealt with the contribution of $^3He$ to tritium generation. As a sample case, the contribution of $^3He$ to the tritium generation in Wolsong #1 was evaluated and compared to the measured values. According to the result of this study, it is concluded that $^3He$ in coolant contributes very much to the tritium generation but that in moderator shows negligible effects due to the low solubility and $^4He$ cover gas. At the beginning of the plant operation, the contribution of $^3He$ is slightly greater than the measured value but agrees well with the measured as the operating time increases.

• Environmental Analysis Health and Toxicology
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• v.18 no.4
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• pp.271-276
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• 2003

The purpose of the present study was to perform experiments of cytotoxicity using HeLa cell and to evaluate the possibility that QSAR is applicable to the cytotoxicity of alkylphenols. Higher toxicities were found in four alkylphenols in the following order: 4-n-Nonylphenol) 4-tert-Octylphenol) 4-n-Octylphenol > 4-n Heptylpheonl. Whereas other alkylphenols were apparently less toxic. By using Percent Hydrophilic Surface Area (PHSA) quantitative structure-activity relationships (QSARs) models were developed: Cytotoxicity (%) = 90.14089-4.72224 PHSA ($R^2$=0.2046, $\alpha$=0.0265). It is concluded that some of the obtained data are useful to determine whether QSAR methods can be of general use in predicting that until further work is undertaken to develop QSARs for a much wider range of homologous series of alkylphenol compounds.

• Journal of Microbiology and Biotechnology
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• v.27 no.7
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• pp.1359-1366
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• 2017

(E)-2-Methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol (MMPP), derived from butenal, is a recently synthesized Maillard reaction product. Owing to its novelty, little is known about the function of MMPP. In this study, we elucidated the effects of MMPP on apoptosis in cervical cancer by using the HeLa cervical cancer cell line, which is widely used in cancer research. We observed that MMPP was cytotoxic to HeLa cells and induced activation of caspase-3, -8, and -9, without affecting the expression of the viral oncogenes E6 and E7. In particular, the expression of the death receptors DR5 and FAS was significantly increased by MMPP treatment. There were no significant alterations of mitochondrial intrinsic factors. Taking all these results together, our findings show that MMPP primarily induces apoptosis in HeLa cervical cancer cells via the extrinsic apoptotic signaling pathway, accompanied by an enhanced expression of death receptors.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.11
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• pp.1535-1542
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• 2009

To find the new use of Korean ginseng and mushroom, crude polysaccharides were prepared from submerged cultures of Hericium erinaceum in the medium supplemented with Korean ginseng extracts. When we fractionated crude polysaccharides (HE-GE-CP-1, 3, and 5) from hot-water extracts of submerged cultures of H. erinaceum with ginseng extracts (1%, 3%, and 5% addition of total medium), the yields of HE-GE-CP-1, 3, and 5 were identified at 5.7, 5.1, and 4.8%, respectively. Among crude polysaccharide fractions, HE-GE-CP-5 was significantly higher (1.89-fold of the saline control) than those of HE-GE-CP-1 (1.64-fold) or HE-GE-CP-3 (1.76-fold) on mitogenic activity of splenocytes. HE-GE-CP-5 also had the more potent bone marrow cell proliferation (1.83-fold) rather than HE-CP or HE-GE-CP-1 or HE-GE-CP-3 (1.59- or 1.44- or 1.69-fold, respectively), and anti-metastatic activity as anti-cancer effect showed the highest prophylactic value (72.4% inhibition of tumor control) in 5% supplementation of ginseng extract. However, the lysosomal phosphatase of macrophage was significantly stimulated after HE-GE-CP-3 treatment (2.03-fold). In addition, the immunostimulating and anti-metastatic crude polysaccharide, HE-GE-CP-5, contained mainly neutral sugars (63.2%) with considerable amounts of uronic acid (19.3%) and a small amount of proteins (8.8%). HE-GE-CP-5 can stimulate immune system to inhibit tumor metastasis, and its anti-tumor metastasis may be associated with macrophages, splenocytes and Peyer's patch cells activation.

• The Journal of Engineering Geology
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• v.31 no.4
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• pp.659-669
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• 2021

The purpose of this study is to elucidate the relationship between occurrence of natural radioactive materials such as ²³⁸U and ²²²Rn and original mixing ratio of helium isotope of groundwater from various geology, and to suggest the underground aquifer environment from helium original mixing data. 9 groundwater samples were collected from five study areas, and ²³⁸U, Rn-222 and helium isotope were analyzed. A high ²³⁸U content of the range of 218~477 ㎍ /L in the groundwater occurs in the twomica granite. ⁴He air-crust mixing ratio and the Rn-222 content show a rough relation, that is, Rn-222 content increases according to the increase of ⁴He crust mixing ratio. Because of helium and radon are an inert gas, their behavior in underground environment is assumed as an analogous. The ²³⁸U content and He isotope in groundwater does not show any distinct correlation. The groundwater can be classified as three groups (air, air-crust mixing, crust-mantle mixing origin) on the diagram of ³He/⁴He vs ⁴He/²⁰Ne, which is composed of original mixing line from air-crust-mantle end members. This original mixing of helium can provide the information of underground aquifer characteristic such as the connection with surface environment or isolation condition from air environment.

• The Journal of Engineering Geology
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• v.21 no.1
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• pp.65-77
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• 2011

Hydrochemical and carbon isotopic (${\delta}^{13}C_{DIC}$) analyses of 11 water samples, and noble gas isotopic analyses of 8 water samples collected in the Kyeoungbuk and Kangwon areas of Korea were performed to determine their hydrochemical characteristics and to interpret the source of noble gases and $CO_2$ gas in the water. The carbonated mineral waters are weakly acidic (PH = 5.59-6.04), and electrical conductivity ranges from 302 to $864\;{\mu}S/cm$. The chemical composition of all the water samples is Ca-$HCO_3$ type. The high contents of Fe and Mn exceed the safe limits for drinking water. The ${\delta}^{13}C_{DIC}$ values of the samples range from -5.30‰ to -2.84‰, indicating that the carbon is supplied mainly from a deep-seated source and to a lesser degree from an inorganic carbonate source. The $^3He/^4He$ ratios of the samples range from $1.51{\times}10^{-6}$ to $6.45{\times}10^{-6}$. The samples plot into three groups on a $^3He/^4He$ versus $^4He/^{20}Ne$ diagram: the deep-seated field (e.g., a mantle source), the atmospheric field, and the air-mantle mixing field. A wide range of $^4He/^{20}Ne$ ratios is observed ($0.036{\times}10^{-6}$ to $1.76{\times}10^{-6}$), indicating that while radiogenic $^4He$ is dominant in these water samples, mantle-origin He is also present. The supply of $CO_2$ gas and noble gases from a deep-seated source to carbonated waters is inferred to be controlled by geological structures such as faults and geological boundaries.

• Journal of Information Display
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• v.10 no.4
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• pp.195-201
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• 2009

The temporal dark- and bright-image sticking phenomena were examined relative to the He contents under 11% Xe content in the 50-in HD and FHD AC-PDPs with a ternary gas mixture (Xe-He-Ne). To compare the temporal dark- and bright-image sticking phenomena under various He contents, the differences in the disappearing time, display luminance, perceived luminance, infrared emission, color coordinate, color temperature, and discharge current before and after discharge were measured under 0, 35, 50, and 70% He contents. It was found that temporal dark- and bright-image sticking were reduced in proportion to the increase in He %. Thus, a high He content contributes to the reduction of temporal dark- and bright-image sticking.

• Journal of Fashion Business
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• v.9 no.4
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• pp.79-93
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• 2005

'Chunhyangjeon' was written by an anonymous author in the mid-period of Chosun Dynasty. The personalities of characters and the styles of dress of men in 'Chunhyangjeon' recreated their clothing to one that is more similar to the descriptions in the literature text can be described as follows. Lee, Mongyong was a young man, but he was a man of integrity and honor. In outwear he wore 'Hat(Heulip)' and 'Dopo' and Taesahae. When he earned his title, he wore 'Pokdu' with flowers and 'Angsam(ceremonial robe)'. After he became a secret royal inspector, in order to disguised on himself as a poor man he wore worn-out 'Heuklip' and 'Dopo' and Jipsin. Bangja who was a servant of Lee, Mongyong wore 'Beonggeoji' and 'Kwaeja' and 'Mituli'. Byun, Hacdo was a rash and greedy character, he wore 'Oklolip' and 'Cheopli' and 'mokhwa' when he was on the way to his post. Yeokjol was low grade official wore 'Jeonlip' and 'Cheopli' and 'Red shoulder band' and 'Mituli'.