• Journal of Magnetics
• /
• 제19권4호
• /
• pp.365-371
• /
• 2014

The aim of this study was to evaluate the utility of 3-D images by comparing and analyzing reconstructed 3-D images from fast spin echo images of MRI cholangiopancreatography (MRCP) images using maximum intensity projection (MIP) with the subtraction images derived from dynamic tests of magnetic resonance mammography. The study targeted 20 patients histologically diagnosed with pancreaticobiliary duct disease and 20 patients showing pancreaticobiliary duct diseases, where dynamic breast MR (magnetic resonance) images, fast spin echo imaged of pancreaticobiliary duct, and 3-D reconstitution images using a 1.5T MR scanner and 3.0T MR scanner were taken. As a result of the study, the signal-to-noise ratio in the subtracted breast image before and after administering the contrast agent and in the reconstructed 3-D breast image showed a high ratio in the reconstructed image of lesional tissue, relevant tissue, and fat tissue. However, no statistically meaningful differences were found in the contrast-to-noise ratio of the two images. In the case of the MRCP image, no differences were found in the ratios of the fast spin echo image and reconstructed 3-D image.

• 융합신호처리학회논문지
• /
• 제9권3호
• /
• pp.179-187
• /
• 2008

본 논문에서는 저가의 광통신용 단일모드 광섬유와 편광소멸기를 이용한 비편광 광섬유 자이로스코프(D-FOG)를 설계/제작하여, 성능을 평가하였다. D-FOG의 위상오차를 줄이기 위해 사용광원의 전류 및 온도 안정화 회로를 제작하여 그 성능을 분석하였다. 제작된 전류 및 온도 안정화 회로의 전류 안정도는 $200{\mu}A$ 미만, 온도 안정도는 $0.0098^{\circ}C$로 양호한 성능을 보였다. 또한, 본 논문에서 제작된 D-FOG의 회전 각속도 측정 범위는 ${\pm}50^{\circ}/s$, Scale factor error는 2.8881%로 양호한 선형성을 보였으며, zero bias drift는 $19.49^{\circ}/h$의 bias 안정도를 보였다. 이는 고가인 고복굴절 편광 유지 광섬유를 이용해 제작된 기존의 FOG에 비해 높은 가격효율성을 갖는 저가의 FOG 제자의 가능성을 보여준다.

• JSTS:Journal of Semiconductor Technology and Science
• /
• 제14권1호
• /
• pp.109-116
• /
• 2014

This paper presents a high-efficiency digital class-D audio amplifier using a composite interpolation filter for portable audio devices. The proposed audio amplifier is composed of an interpolation filter, a delta-sigma modulator, and a class-D output stage. To reduce power consumption, the designed interpolation filter has an optimized composite structure that uses a direct-form symmetric and Lagrange FIR filters. Compared to the filters with homogeneous structures, the hardware cost and complexity are reduced by about half by the optimization. The coefficients of the digital delta-sigma modulator are also optimized for low power consumption. The class-D output stage has gate driver circuits to reduce shoot-through current. The implemented class-D audio amplifier exhibited a high efficiency of 87.8 % with an output power of 57 mW at a load impedance of $16{\Omega}$ and a power supply voltage of 1.8 V. An outstanding signal-to-noise ratio of 90 dB and a total harmonic distortion plus noise of 0.03 % are achieved for a single-tone input signal with a frequency of 1 kHz.

• 한국BIM학회 논문집
• /
• 제9권1호
• /
• pp.11-21
• /
• 2019

Recently, there is an increase in fire incidents in building structures. Due to this, the importance of fire-damaged buildings' safety diagnosis and evaluation after fire is growing. However, the existing fire-damaged safety diagnosis and evaluation methods are personnel-oriented, so the diagnostic results are intervened by investigators' subjectivity and unquantified. Thus, improper repair and reinforcement can result in secondary damage accidents and economic losses. In order to overcome these limitations, this study proposes using 3D laser scanning technology. The case analysis of fire-damaged building structures was conducted to verify the effectiveness of accuracy and manpowering by comparing the existing method and the proposed method. The proposed method using 3D laser scanning technology to obtain point cloud data of fire-damaged field. The point cloud data and BIM model is combined to inspect the fire-damaged area and depth. From inspection, quantified repair and reinforcement quantity take-off can be acquired. Also, the proposed method saves half of the manpowering within same time period compared to the existing method. Therefore, it seems that using 3D laser scanning technology in fire-damaged safety diagnosis and evaluation will improve in accuracy and saving time and manpowering.

• 국제학술발표논문집
• /
• The 5th International Conference on Construction Engineering and Project Management
• /
• pp.279-286
• /
• 2013

This paper introduces a new method for identification of building energy performance problems. The presented method is based on automated analysis and visualization of deviations between actual and expected energy performance of the building using EPAR (Energy Performance Augmented Reality) models. For generating EPAR models, during building inspections, energy auditors collect a large number of digital and thermal imagery using a consumer-level single thermal camera that has a built-in digital lens. Based on a pipeline of image-based 3D reconstruction algorithms built on GPU and multi-core CPU architecture, 3D geometrical and thermal point cloud models of the building under inspection are automatically generated and integrated. Then, the resulting actual 3D spatio-thermal model and the expected energy performance model simulated using computational fluid dynamics (CFD) analysis are superimposed within an augmented reality environment. Based on the resulting EPAR models which jointly visualize the actual and expected energy performance of the building under inspection, two new algorithms are introduced for quick and reliable identification of potential performance problems: 1) 3D thermal mesh modeling using k-d trees and nearest neighbor searching to automate calculation of temperature deviations; and 2) automated visualization of performance deviations using a metaphor based on traffic light colors. The proposed EPAR v2.0 modeling method is validated on several interior locations of a residential building and an instructional facility. Our empirical observations show that the automated energy performance analysis using EPAR models enables performance deviations to be rapidly and accurately identified. The visualization of performance deviations in 3D enables auditors to easily identify potential building performance problems. Rather than manually analyzing thermal imagery, auditors can focus on other important tasks such as evaluating possible remedial alternatives.

• Molecular & Cellular Toxicology
• /
• 제5권4호
• /
• pp.346-353
• /
• 2009

Drug metabolism is a critical determinant of the therapeutic and adverse effects of many psychotropic drugs. The metabolism depends on the pharmacokinetics of a drug, which includes its absorption, distribution, and elimination. Psychotropic drugs are metabolized mainly by cytochrome P450 (CYP) enzymes; about 20 of these enzymes exist and they are often responsible for the rate-limiting step of drug metabolism. CYP2D6 is the best-characterized P450 enzyme that exhibits polymorphism in humans. This study determined the relationship between the CYP2D6*10 (P34S) polymorphism and the response to mirtazapine in 153 Koreans with major depressive disorder (MDD). The genotype frequencies were compared using logistic regression analysis, and between-genotype differences in the decrease in the 21-item Hamilton Depression (HAMD21) score over the 12-week treatment period were analyzed using a linear regression analysis. The proportion of remitters was lower in patients with MDD possessing the S allele than in P allele carriers after 2 weeks of mirtazapine treatment. Similarly, the reductions in the HAMD21 and Clinical Global Impression (CGI) scores in S allele carriers were smaller than those in patients with the P allele after 2 weeks of mirtazapine treatment. In the analysis of depression symptoms, the sleep and delusion scores had smaller reductions in S allele carriers. Based on the Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS), the psychic adverse effects of mirtazapine were associated with CYP2D6 P34S, while weight gain was not. These results suggest that CYP2D6 P34S affects the outcome of mirtazapine treatment in patients with MDD, and that this polymorphism may be a good genetic marker for predicting the clinical outcome of mirtazapine treatment.

• Nutrition Research and Practice
• /
• 제7권6호
• /
• pp.481-487
• /
• 2013

High-fat diet up-regulates either insulin resistance or triglycerides, which is assumed to be related to the expression of peroxisome proliferator-activated receptor (PPAR)-${\alpha}$ and PPAR-${\gamma}$. The beneficial effects of vitamin E on insulin resistance are well known; however, it is not clear if vitamin E with a high-fat diet alters the expression of PPAR-${\alpha}$ and PPAR-${\gamma}$. We investigated the effects of d-${\alpha}$-tocopherol supplementation on insulin sensitivity, blood lipid profiles, lipid peroxidation, and the expression of PPAR-${\alpha}$ and PPAR-${\gamma}$ in a high-fat (HF) diet-fed male C57BL/6J model of insulin resistance. The animals were given a regular diet (CON; 10% fat), a HF diet containing 45% fat, or a HF diet plus d-${\alpha}$-tocopherol (HF-E) for a period of 20 weeks. The results showed that the HF diet induced insulin resistance and altered the lipid profile, specifically the triglyceride (TG) and total cholesterol (TC) levels (P < 0.05). In this animal model, supplementation with d-${\alpha}$-tocopherol improved insulin resistance as well as the serum levels of TG and very-low-density lipoprotein-cholesterol (VLDL-C) (P < 0.05). Moreover, the treatment decreased the levels of malondialdehyde (MDA) in the serum and liver while increasing hepatic PPAR-${\alpha}$ expression and decreasing PPAR-${\gamma}$ expression. In conclusion, the oral administration of d-${\alpha}$-tocopherol with a high-fat diet had positive effects on insulin resistance, lipid profiles, and oxidative stress through the expression of PPAR-${\alpha}$ and PPAR-${\gamma}$ in a high-fat diet-fed male mice.

• 한국건설관리학회:학술대회논문집
• /
• 한국건설관리학회 2007년도 정기학술발표대회 논문집
• /
• pp.864-867
• /
• 2007

U-City건설 사업, 행정중심복합도시 건설 등 최근 도심 개발 사업이 대형화되고, 복합화되고 정보 인프라의 증가로 인하여 건설 산업이 정보화, 첨단화되면서 프로젝트의 기획단계의 중요성이 나날이 증가하고 있다. 최근 건설 분야에서 3D CAD 및 GIS 기술과의 융합 등 IT를 접목한 컨버전스를 통해 실제 건축물을 구축하기 전 건설 사업 단계별로 미리 시뮬레이션을 통해 의사결정을 지원할 수 있는 애플리케이션이 활발히 개발되고 있다. 하지만 프로젝트의 초기단계인 기획단계의 경우에는 업무의 특성상 전문가의 경험에 의존하는 경향이 있고, 행정적인 업무를 수반하기 때문에 IT기술을 활용한 어플리케이션을 적용하는 데 있어서 한계를 가지고 있다. 따라서 기획단계의 의사결정 지원을 위해 최근 이슈화되고 있는 3D CAD 데이터에 기획 단계에서의 설계요소 정보, GIS 기술을 연계하여 프로젝트 초기 단계인 기획단계의 업무 효율을 향상시킬 수 있는 방향을 제시하고자 한다.

• Journal of Animal Science and Technology
• /
• 제57권10호
• /
• pp.37.1-37.9
• /
• 2015

This study was performed to investigate the effects of the low plane of nutrition on growth and meat quality of finishing pigs. A total of 136 crossbred barrows and gilts weighing approximately 55 kg were allotted to 8 pens, with 17 animals housed per pen, in a 2 (sex) ${\times}$ 2 (nutrition) factorial arrangement of treatments. The animals allotted to a medium plane of nutrition (MPN) received a finisher phase 1 (P1) diet containing 3.47 Mcal DE/kg and 0.92 % lysine and a P2 diet containing 3.40 Mcal DE/kg and 0.78 % lysine for 35 d and 36/43 d, respectively; the animals allotted to the low plane of nutrition (LPN) received only a P2 diet containing 3.00 Mcal DE/kg and 0.68 % lysine 7 d longer than MPN. The animals were slaughtered following the feeding trial, after which the loin, ham, Boston butt, and belly were taken from a total of 24 animals, with the average live weight being 120 kg, and their physicochemical and sensory quality traits were analyzed. Average daily gain did not differ between MPN and LPN during either P1 or P2. Average daily feed intake was greater (P < 0.05) in LPN vs. MPN during both phases whereas the opposite was true for the gain:feed ratio. Backfat thickness (BFT) was less in LPN vs. MPN (21.7 vs. 24.1 mm at 115 kg). The plane of nutrition influenced no effect on any of the physicochemical characteristics of fresh loin, ham, or Boston butt analyzed in the present study. Fresh hams from LPN exhibited superior aroma and odor scores than those from MPN; however, sensory quality traits were not influenced by the plane of nutrition in other fresh primal cuts or cooked meat. Instead, fresh primal cuts and cooked meat from gilts rendered superior physicochemical characteristics and sensory scores, respectively, than those from barrows. Results suggest that the low plane of nutrition may be useful to increase the slaughter weight of finishing pigs with a moderately high BFT by virtue of its BFT-lowering effect with or without exerting a slightly positive influence on pork quality.

• 한국축산식품학회지
• /
• 제18권2호
• /
• pp.132-141
• /
• 1998

This study were carried out for investigation of physicochemical and sensory characteristics of shelf-life of Korean vaccum packaged chilled pork hams for export. The samples were stored at 0$\pm$1$^{\circ}C$ (A and B companies) and 2$\pm$1$^{\circ}C$ (C and D companies). In the proximate analysis of composition of hams, moistures were 75.36~76.57%, crude proteins 19.26~21.08%, crude fat 1.40~3.69% and crude ash 1.03~1.13%. TBA values were 0.192~0.264 mgMA/kg and did not change much during all storage times regardless of storage temperature. VBN values were 12.14~14.01mg / 100g after 50 days in the storage at $0^{\circ}C$, but the samples stored at 2$^{\circ}C$ exceeded 20mg/100g at 50 days. The values of pH were 5.71~6.50, which are higher than those of loins during all storage times. Purge losses were 1.23~1.98% at the initial time and 2.83~10.59% after 50 days. So, the variation among samples appeared to be large. Cooking losses appeared to be 33.86~56.24%. In the result of sensory evaluation of cooked meat, the ham of B company obtained good scores in all items. But, after 20 days, all samples were not significantly different in total acceptability.