• Title/Summary/Keyword: HA/PCL

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Functional Evaluation after Arthroscopic Reconstruction in Isolated and Combined Injury of Posterior Cruciate Ligament (후방십자인대의 단독 및 동반 손상에서 관절경적 재건술 후 기능적 평가)

  • Lee Kwang-Won;Lee Seung-Hun;Park Jae-Guk;Kim Ha-Yong;Kim Byung-Sung;Choy Won-Sik
    • Journal of the Korean Arthroscopy Society
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    • v.6 no.2
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    • pp.115-120
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    • 2002
  • Purpose : To compare the functional evaluation with the posterior translation after arthroscopic PCL reconstruction in isolated and combined PCL-deficient knees. Materials and Methods : We retrospectively evaluated 45 patients with PCL-deficient knees who were treated by arthroscopic PCL reconstruction using Achilles tendon allograft from June 1994 to June 2000. The differences of posterior translation were measured with posterior stress lateral radiographs and KT-2000 arthrometer. The functional results were evaluated using the Lysholm knee score and IKDC evaluation form. Results : Preoperative mean side to side differences of the posterior translation were 11.83 mm in isolated PCL-deficient knees and 12.7 mm in combined PCL-deficient knees respectively. At the last follow-up in isolated and combined PCL-deficient knees, the mean radiographic side to side differences of the posterior translation were 6.38 mm and 6.7 mm, the average corrected 20 Ib posterior displacements using KT-2000 arthrometer were 3.5 mm and 4.1 mm, the mean Lysholm score were 87.4 and 81.2, the grade A and B of IKDC evaluation form were 16 cases $(88.9\%)$ and 23 cases $(85.2\%)$, respectively. Conclusion : The functional results had no relationship with the degree of posterior translation after arthroscopic PCL reconstruction. Tendency of posterior translation may be influenced by associated injury of the knee.

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Preparation and Characterization of Porous Polycaprolactone Membrane for Tissue Engineering (조직공학용 다공성 Polycaprolactone 멤브레인의 제조 및 특성)

  • Kim, Jin-Tae;Kim, Tae-Hyung;Choi, Jae Ha
    • Membrane Journal
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    • v.26 no.1
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    • pp.26-31
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    • 2016
  • Polycaprolactone (PCL) has been fabricated into the membrane type scaffolds of 3 dimensional pore network for the tissue engineering applications by the blade method of salt (NaCl) leaching and solution casting. In this study, the experimental designs have each conditions of drying temperature, salt particle size, salt content. The modified dispensing pump connected up to homogenizing mixer system is used for mixing the $PCL/CHCl_3$ solution and NaCl particles. The membrane fabricated use by the film applicator to poured mixed solution on the glass plate. The great pore by NaCl particles and the small pore by the evaporated $CHCl_3$ in the frame wall of great pores are multiply formed in membrane scaffolds.

Intraligamentous Ganglionic Cyst of the Posterior Cruciate Ligament: A Case Report (후방십자인대 내에 발생한 관절내 결절종 - 1례 보고 -)

  • Jeong, Jae-Heon;Baek, Ji-Hoon;Lee, Sang-Hak;Jung, Ho-Joong;Ha, Yong-Chan
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.9 no.1
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    • pp.69-71
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    • 2010
  • Ganglionic cyst formation within the posterior cruciate ligament (PCL) of knee has not been reported. We describe a case of an intraligamentous ganglionic cyst of PCL. Arthroscopic technique through both the posteromedial and posterolateral portals was used for approach. Using probe, PCL was splitted and perforated ganglionic cyst at tibial attachement side. At 2 years follow up, the patient was free of symptoms with a full range of motion and follow-up MR image showed that there was no recurred ganglionic cyst.

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A Comparison of the Effects of Silica and Hydroxyapatite Nanoparticles on Poly(ε-caprolactone)-Poly(ethylene glycol)-Poly(ε-caprolactone)/Chitosan Nanofibrous Scaffolds for Bone Tissue Engineering

  • Hokmabad, Vahideh Raeisdasteh;Davaran, Soodabeh;Aghazadeh, Marziyeh;Alizadeh, Effat;Salehi, Roya;Ramazani, Ali
    • Tissue Engineering and Regenerative Medicine
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    • v.15 no.6
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    • pp.735-750
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    • 2018
  • BACKGROUND: The major challenge of tissue engineering is to develop constructions with suitable properties which would mimic the natural extracellular matrix to induce the proliferation and differentiation of cells. Poly(${\varepsilon}$-caprolactone)-poly(ethylene glycol)-poly(${\varepsilon}$-caprolactone) (PCL-PEG-PCL, PCEC), chitosan (CS), nano-silica ($n-SiO_2$) and nano-hydroxyapatite (n-HA) are biomaterials successfully applied for the preparation of 3D structures appropriate for tissue engineering. METHODS: We evaluated the effect of n-HA and $n-SiO_2$ incorporated PCEC-CS nanofibers on physical properties and osteogenic differentiation of human dental pulp stem cells (hDPSCs). Fourier transform infrared spectroscopy, field emission scanning electron microscope, transmission electron microscope, thermogravimetric analysis, contact angle and mechanical test were applied to evaluate the physicochemical properties of nanofibers. Cell adhesion and proliferation of hDPSCs and their osteoblastic differentiation on nanofibers were assessed using MTT assay, DAPI staining, alizarin red S staining, and QRT-PCR assay. RESULTS: All the samples demonstrated bead-less morphologies with an average diameter in the range of 190-260 nm. The mechanical test studies showed that scaffolds incorporated with n-HA had a higher tensile strength than ones incorporated with $n-SiO_2$. While the hydrophilicity of $n-SiO_2$ incorporated PCEC-CS nanofibers was higher than that of samples enriched with n-HA. Cell adhesion and proliferation studies showed that n-HA incorporated nanofibers were slightly superior to $n-SiO_2$ incorporated ones. Alizarin red S staining and QRT-PCR analysis confirmed the osteogenic differentiation of hDPSCs on PCEC-CS nanofibers incorporated with n-HA and $n-SiO_2$. CONCLUSION: Compared to other groups, PCEC-CS nanofibers incorporated with 15 wt% n-HA were able to support more cell adhesion and differentiation, thus are better candidates for bone tissue engineering applications.

EFT and Korean Medicine Treatment for ASD Induced by a Traffic Accident: A Case Report (교통사고 상해증후군 환자의 급성 스트레스 장애에 시행한 한의치료와 EFT 치료 치험 1례)

  • Chaewon Son;Jinyoug Kang;Backjun Kim;Wonjeong Ha;Hwan Kim
    • Journal of Oriental Neuropsychiatry
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    • v.34 no.2
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    • pp.115-124
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    • 2023
  • Objectives: To report the efficacy of using EFT and Korean medicine treatment for ASD induced by a traffic accident. Methods: We treated ASD symptoms with Korean medicine (acupuncture, cupping, interferential current therapy, herbal acupuncture therapy). To evaluate results of this treatment, Korean version of PTSD Checklist-5 (PCL-5-K), Beck Depression Inventory (BDI), Insomnia Severity Index (ISI), and Numeric rating scale (NRS) at first visit, 5 weeks, and 12 weeks were used. Results: Korean version of PTSD Checklist-5 (PCL-5-K), Beck Depression Inventory (BDI), Insomnia Severity Index (ISI), and Numeric rating scale (NRS) showed improvements after treatments. Conclusions: This study suggests that Korean medicine and EFT treatment might be effective for ASD.

Anti-Proliferative Effect of Tetraphenylporphine (TPP) as an Iron Chelator on Vascular Smooth Muscle Cells and its Release Profiles from Polymer Coating Layer (철 킬레이터로서의 tetraphenylporphine의 혈관평활근세포의 성장억제효과와 고분자 코팅막으로부터의 방출 특성)

  • Park, Min-Hee;Kang, Soo-Yong;Park, Hyun-Jeong;Seo, Jin-Seon;Park, Young-A;Kim, Ji-Eun;Kim, Yang-Geun;Whang, Bae-Geon;Munkhjargal, Odonchimeg;Shim, Young-Key;Kho, Weon-Gyu;Lee, Woo-Kyoung
    • Journal of Pharmaceutical Investigation
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    • v.38 no.2
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    • pp.93-98
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    • 2008
  • The drug-eluting stent (DES) implantation is a widely acceptable treatment for coronary heart disease. It was reported that iron chelator had anti-proliferative effect on human vascular smooth muscle cells (HA-VSMCs). In this study, tetraphenylporphine (TPP) was selected as an iron chelator and drug for DES. MTT assay showed that TPP had antiproliferative effect on HA-VSMCs. TPP and polycaprolactone (PCL) were coated onto stainless steel plate using a spraycoating method. From the surface morphology examination of the coated plate by SEM, smooth polymer coating layer could be observed. The thickness of coating layer could be controlled by changing repeating time of coating. From in vitro release test, sustained release of TPP was observed from plate during two weeks. Thus, TPP as iron chelator can be used as drug for stent coating because of its antiproliferative effect and sustain release profile.

Arthroscopic Posterior Cruciate Ligament Reconstruction with Preservation of the Remnant Posterior Cruciate Ligament (남아 있는 후방 십자 인대 다발을 보존한 관절경하 후방 십자 인대 재건술)

  • Ahn Jin Hwan;Ha Kwon Ik;Chung Yoon Sung;Yang Il Soon
    • Journal of the Korean Arthroscopy Society
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    • v.4 no.2
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    • pp.97-104
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    • 2000
  • Purpose : The majority of PCL deficient knees have some intact remnant PCL bundles. In these cases, the remnant PCL bundles were removed fur easy passage of graft(especially in bone-patellar tendon-bone graft). The purpose of study is to report the results of PCL reconstruction by posterior transseptal portal technique and by preserving the remnant posterior cruciate ligament bundles. Materials & Methods : From November 1993 to June 1999, 44 arthroscopic posterior cruciate ligament reconstructions have been performed by one surgeon. We studied 37 knees those were followed up over 1 year among them. The mean age($14\~56$ years) was 31.8 years. The average follow-up period was 17.8 months($12\~61$ months). The graft materials were 29 double-loop hamstring autografts, 4 double-loop hamstring allografts and 4 Achilles tendon-bone allograft. Results : There are significant improvement of the preoperative subjective symptoms. The last follow-up shows that the average Lysholm knee score was markedly improved from 59.8 pre-operation to 89.2 post-operation and the average KT 2000 side difference was decreased from 11.1mm pre-operation to 2.3 mm post-operation. Follow-up MRI showed that the graft was healed with remnant posterior cruciate ligament bundles as one ligament. Conclusion : The posterior trans-septal portal makes it possible to locate the exact tibial tunnel. The arthroscopic PCL reconstruction preserving the remnant of original PCL bundles seems to provide the good result.

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Radiofrequency Shrinkage Method for Minor Degree of Cruciate Ligament Injury of knee joint (경도의 슬관절 십자 인대 손상환자에 대하여 시행한 열 위축술)

  • Moon Young Lae;Ha Sang Ho;You Jae Won;Joo Jeong Yong;Ju Pyong
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.1 no.1
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    • pp.37-42
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    • 2002
  • Purpose : To report a short-term clinical results and technical method of thermal shrinkage with radiofrequency device for anterior and posterior cruciate ligament laxity which is not suitable to indications of reconstructive surgery. Materials and Methods : Nine cases of anterior cruciate ligament injuries (ACL), 5 cases of posterior cruciate ligament (PCL) injuries and 3 cases of combined anterior and posterior cruciate ligament injuries, in which the condition is not indicated as reconstructive surgery, are investigated. The follow-up period averaged 6 months. Results : Instability in living activity, limping and pain were improved with excellent results. But, posterior cruciate ligament thermal shrinkage revealed as recurrent knee laxity progressively Conclusions : The result of thermal shrinkage for partial tear of cruciated ligament was excellent. We believe this procedure is applicable to partial tear of the ACL or PCL which reconstructive surgery is not indicated. Long-term follow-up results were needed.

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Differences in Functional Recovery according to Exercise Rehabilitation after Posterior Cruciate Ligament with or without Posterolateral Complex Reconstruction (뒤십자인대 및 뒤가쪽 복합체 동반 수술 후 재활운동에 따른 기능회복 차이)

  • Kim, Hyun-Mok;Ha, Sunghe;Kong, Doo-Hwan;Kim, Chang-Kook
    • Journal of the Korea Convergence Society
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    • v.13 no.3
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    • pp.327-335
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    • 2022
  • This study aimed to compare functional recovery after rehabilitation exercise between isolated PCL reconstruction and combined PLC reconstruction. Patients were divided into two groups: those who had isolated PCL reconstruction (n = 16) and those who had combined PLC reconstruction (n = 16). We assessed knee joint ligament laxity, subjective questionnaires, and isokinetic muscle function before, after 12, and 24 weeks of a rehabilitation exercise program. In both groups, there were significant differences in knee joint laxity (p = 0.048), IKDC subject score (p < 0.001), Lysholm knee (p < 0.001), Tegner activity scale (p = 0.027), and isokinetic muscle deficit (p = 0.040) by estimated period. However, no significant difference between groups was observed (p > 0.05). These results suggest that rehabilitation exercise after isolated PCL and combined PLC reconstruction influenced structural, subjective, functional recovery positively.

PHOSPHORUS NITRIDE FILMS ON InP SURFACE BY PHOTO-CVD (광CVD에 의한 InP기판 위에 질화인막의 성장)

  • Hong, Youg-Tae;Lee, Jae-Hak;Jeong, Yoon-Ha;Bae, Young-Ho;Kim, Kwang-Ill;Jeong, Wook-Jin
    • Proceedings of the KIEE Conference
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    • 1989.07a
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    • pp.386-389
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    • 1989
  • Phosphorus nitride films on InP surface were grown by a Photo-CVD (chemical vapor deposition) technique over 100-250 $^{\circ}C$ range of substrate temperature, which is based on direct photolysis of $PCl_3/H_2$ and $NH_3$ gas mixtures by 185nm ultraviolet light from a low pressure mercury lamp. The film growth rate ed the refractive index(n) were shown about 700-800 ${\AA}/hr$ and 1.7-1.8, respectively. Composition ratio and interface properties were analyzed by AES(Auger Electron Spectroscopy) and XPS (X-ray Photoelectron Spectorscopy) technique.

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