• Archives of Pharmacal Research
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• 제12권2호
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• pp.135-137
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• 1989

A convenient route is reported for the synthesis of certain series of 4H-thieno[2,3-b][1]benzothiopyran-4-ones, carrying various substituents at position 2 such as arylazomethines (7,8), thiazolidin-4-ones (9-13), ${\alpha},\;{\beta}-unsaturated$ ketones (16,17), 2-pyridones (19-23), tetrahydrothiophen-4-ones (24,28), and nitroalkenes (29,30), as potential schistosomicidal or antihistaminic agents.

• 한국초지조사료학회지
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• 제17권3호
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• pp.257-264
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• 1997

This study was conducted to assess present situiatioq of oversowing grassland yield and vegetational succession of abondoned since 6 years passed grassland in Wonju. The highest annual h s h weight yield was 28ton/ ha and the lowest was I lton/ha and the grass rate of investigated oversowing grasslands were range from 19.5% to 9lS%. The soil properties of abandoned oversowing grassland, such as soil pH content of organic matter, available phosphorus, exchangeable potasium, calcium, and magnesium were 5.7, 3.88%, 3lppm, O.lme1100g 4.9meI 100g and 2.3me/100g, respectively. The floristic composition of abandoned grassland were composed 26 species of vascular plants. The dominant species based on SDR, of grassland were Miscanthus sinensis var. purpurascens(56.32%). Artemisia feddei(48.62%) and Dactylis glomerata(43.85%). The biological spectra showed the H-$D_1$-$R_5$-e type.

• 한국정보과학회논문지:소프트웨어및응용
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• 제28권5호
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• pp.402-411
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• 2001

H.263 압축 방식은 실현하는데 여러 가지 문제가 있지만 그 중에서 그 대표적인 것은 인코딩 과정에서의 압축 시간이 오래 걸린다는 것이고 다른 한 가지는 과도한 압축률에 의한 복원된 이미지 화질 저하이다. 이 논문에서는 H.263에서의 압축 속도 향상과 복원 이미지의 화질 이미지의 화질 보상에 대한 두 가지 새로운 방법을 제안하였다. 압축 속도를 향상시키기 위해서 움직임 벡터를 찾는 알고리즘을 개선하여 새로운 4단계 탐색 알고리즘을 제안하였다. 또한 화질을 보상하기 위해 디코더에서 블록 아티팩을 제거하고 복원 이미지를 선명하게 하는 알고리즘을 제안하였다. 여기서 화질 보상은 원본 이미지와 동일하게 만드는 것이 아니라 인간이 더 좋은 영상으로 인식하도록 하는 걸 목적으로 한다. 우리가 제한한 알고리즘에 의해서 압축 속도는 초당 2.5에서 17 프레임으로 증가하였고 블록 아티팩을 제거하고 명암 대비를 높임으로써 보기 좋은 영상을 제공하였다.

• 한국수정란이식학회지
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• 제28권4호
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• pp.349-353
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• 2013

The objective of this study was to compare the effect of semen extenders on the sperm motility, viability, acrosome integrity and functional integrity of plasma membrane (HOST: hypo-osmotic swelling test) during liquid preservation of Korean Native boar semen. In this experiment, semen was diluted in Androhep plus, Beltsville Thawing Solution (BTS), ModenaTM, Seminark and Vitasem LD. Sperm-rich fractions were collected from three Korean Native boars and sub-samples were diluted ($30{\times}10^6$ spermatozoa/ml) in different semen extenders. Semen samples were stored at $17^{\circ}C$ for 96 hours. On everyday (0, 24, 48, 72, 96 h) after storage, the sperm characteristics relevant for fertility, such as sperm motility, viability, acrosome integrity and HOST positive were evaluated. The motility of spermatozoa stored in different extenders was no significantly different among other extenders (P>0.05). Also, no difference was observed among samples processed with different extenders in the percentage of sperm viability, acrosome integrity and HOST positive. All extenders maintained a high percentage (70%) of sperm motility, viability and acrosome integrity through 96 h of storage. The result of this study show that there was no significant differences among extenders in their capacity to preserve motility, viability and membrane integrity of spermatozoa from normal, fertile Korean Native boars for 96 h of liquid preservation at $17^{\circ}C$.

• Reproductive and Developmental Biology
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• 제28권1호
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• pp.53-57
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• 2004

The study was carried out to investigate the effects of morphology, reproductive cycle, incubation time and activation of oocytes on in vitro maturation of cat oocytes and development of IVM/IVF embryos. The results were summarized as follows: 1. When recovered from ovaries collected at different stages of the reproductive cycle (inactive, follicular and luteal stage), the developmental rates of oocytes to GV and MI stage were 72.5% and 27.5%, 57.5% and 7.5%, 62.5% and 17.5%, respectively. 2. The developmental rates of oocytes with cumulus cells to GV and MI stage in different conditions of incubation (5% $CO_2$ , 95% $O_2$ and 10% $CO_2$, 90% $O_2$) were 70.0% and 27.5%, 52.5% and 20.0%, 55.0% and 12.5%, respectively. 3. The developmental rates to GV and MI oocytes when cultured at different time of incubation (17∼20, 21∼24, 25∼28 and 29∼32 h) were 67.5% and 20.0%, 67.5% and 30.0%, 62.5% and 22.5%, 65.0% and 15.0%, respectively. 4. The fertilization and cleavage rates of freshly collected oocytes with and without cumulus cells were 72.5% and 25.0%, 37.5% and 7.5%, respectively. The rates were greater in oocytes with cumulus cells than those without cumulus cells. 5. The fertilization and cleavage rates of oocytes recovered from ovaries collected at different stages of the reproductive cycle (inactive, follicular and luteal stage) were 75.0% and 25.0%, 40.0% and 7.5%, 50.0% and 15.0%, respectively.

• International Journal of Aeronautical and Space Sciences
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• 제17권1호
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• pp.132-138
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• 2016

Korea Aerospace Research Institute (KARI) is developing an electric-driven HALE UAV in order to secure system and operational technologies since 2010. Based on the flight tests and design experiences of the previously developed electric-driven UAVs, KARI has designed EAV-3, a solar-powered HALE UAV. EAV-3 weighs 53kg, the structure weight is 22kg, and features a flexible wing of 19.5m in span with the aspect ratio of 17.4. Designing the main wing and empennage of the EAV-3 the amount of the bending due to the flexible wing, 404mm at 1-G flight condition based on T-800 composite material, and side wind effects due to low cruise speed, $V_{cr}=6m/sec$, are carefully considered. Also, unlike the general aircraft there is no center of gravity shift during the flight because of the EAV-3 is the solar-electric driven UAV. Thus, static margin cuts down to 28.4% and center of gravity moves back to 31% of the Mean Aerodynamic Chord (MAC) comparing with the previously designed the EAV-2 and EAV-2H/2H+ to upgrade the flight performance of the EAV-3.

• Asian-Australasian Journal of Animal Sciences
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• 제17권7호
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• pp.967-972
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• 2004

Four Holstein$\times$Indigenous cows with ruminal canulas were used in a 4$\times$4 Latin square design with 28 d periods to determine the effect of replacing nonforage fiber source (NFFS) from cassava residues for non-fiber carbohydrates (NFC) on ruminal fermentation characteristics and milk production. Dietary treatments contained 17% forage neutral detergent fiber (FNDF) from corn silage and 0, 3, 6 and 9% nonforage NDF from cassava residues and 11% nonforage NDF from other NFFS, so that levels of nonforage NDF were 11, 14, 17 and 20% dry matter (DM). Intakes of DM and net energy for lactation, average daily gain and milk fat percentage were not different (p>0.05). Ruminal pH, ammonia concentrations, acetate to propionate ratios, 24 h in sacco fiber digestibility significantly increased with increasing contents of nonforage NDF from cassava residues. Concentrations of VFA, urinary excretion of purine derivatives, milk protein percentage, production of milk and 4% FCM significantly decreased. These results suggest that NFC in diets is one of the limiting factors affecting productivity of dairy cows in the tropics and thus NFFS is better used as partial replacements for FNDF.

• 한국수정란이식학회지
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• 제28권2호
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• pp.121-125
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• 2013

This study was carried out to investigate the general characteristics of semen such as semen volume, pH, sperm motility and sperm concentration of the semen collected from Shih Tzu dogs (age of 24 to 48 months, weight of 4 to 8 kg) by using the method of digital manipulation of the penis. The effect of preservation temperature and time on motility of fresh semen was also investigated in the present study. Semen was collected for 16 times from 4 male Shih Tzu dogs by multiple ejaculations (four times ejaculation per dog). The average of semen volume, semen pH, sperm motility and sperm concentration of the second fraction containing small volume of the initial third fraction per ejaculation were $2.11{\pm}0.31$ ml, $6.25{\pm}0.07$, $97.59{\pm}1.03%$ and $2.05{\pm}0.14{\times}10^8$ cells/ml, respectively. Average semen volume per ejaculate, semen pH, sperm motility and sperm concentration of the first fraction from the ejaculation were $1.12{\pm}0.15$ ml, $5.99{\pm}0.14$, $16.09{\pm}6.18%$ and $5.16{\pm}2.03{\times}10^5$ cells/ml, respectively. Those of second fraction were $2.07{\pm}0.29$ ml, $6.36{\pm}0.13$, $97.31{\pm}1.36%$ and $2.15{\pm}0.30{\times}10^8$ cells/ml, respectively. Those of third fraction were $2.60{\pm}0.29$ ml, $6.63{\pm}0.08$, $95.72{\pm}1.61%$ and $6.03{\pm}1.83{\times}10^7$ cells/ml, respectively. Sperm motility was significantly higher at $17^{\circ}C$ preservation temperature than at $5^{\circ}C$ or $36^{\circ}C$ during preservation period except 1 h preservation (P<0.05). When preservation temperature was $17^{\circ}C$, sperm motility was $96.69{\pm}1.49%$ at 1 h, $91.38{\pm}1.90%$ at 6 h, $88.38{\pm}2.34%$ at 12 h, $78.13{\pm}4.58%$ at 18 h, $58.44{\pm}8.57%$ at 24 h and $29.56{\pm}5.06%$ at 30 h, respectively.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제14권1호
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• pp.45-51
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• 2011

목 적: Helicobacter pylori (H. pylori) 제균 치료의 적절한 항균제 선택의 기반이 되기 위해 소아에서 H. pylori 항균제 내성률을 알아보고자 하였다. 방 법: 2003년 7월부터 2009년 4월까지 상복부 통증으로 본원을 방문한 환자 중 위 문부 생검 조직 배양에서 H. pylori 가 동정된 균주를 대상으로 항균제 감수성 검사를 시행하였다. 감수성 검사는 clarithromycin과 amoxicillin은 디스크 확산법으로, tetracycline과 metronidazole은 E-test를 시행하였다. 치료 원칙은 감수성 결과가 확인 된 환자는 감수성 결과에 따라 항균제를 선택 하였고, BAM (bismuth subsalicylate, amoxicillin, metronidazole) 또는 OAC (omeprazole, amoxicillin, clarithromycin)를 바탕으로 한 경험적 삼제요법을 택하였다. 치료 실패 시에는 bismuth (또는 bismuth subsalicylate)를 포함한 사제요법을 선택하였다. 결 과: 33명의 환자가 배양검사 양성을 보였고 28명의 환자에서 감수성 검사를 시행하였다. 이 중 항균제 내성을 보인 환아는 9명(32.1%)으로 그 중 7명(25%)이 clarithromycin 내성 균주를 보였고 5명(17.8%)이 metronidazole 내성 균주를 보였다. 대상이 적어 통계적인 분석을 하지 못하였으나 Clarithromycin과 metronidazole의 내성률이 시기적으로 감소하는 추세를 보였다. 결 론: 본 연구는 단일 병원에서 소수의 환아를 대상으로 이루어진 연구로 한계가 있으나, 간접적으로 국내소아 환아에서 분리된 H. pylori의 균주에서도 높은 항균제 내성과 시기적으로 내성률이 변하는 것을 알 수있었다. 따라서 소아 환자에서 적절한 항균제 선택을 제시하기 위한 보다 광범위한 연구가 필요한 것으로 생각한다.

• 대한가정학회지
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• 제23권3호
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• pp.55-61
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• 1985

엿의 간편하고 과학적인 제조방법을 모색하기 위하여 본 실험에서는 옛 문헌을 참고로 하고 예비실험을 통하여 엿 제조가 가능한 곡류, 엿 재료의 배합비 및 전자렌지를 이용한 엿의 적합한 제조조건을 결정하였다. 엿의 적합한 제조조건으로 제조된 각종 엿의 특성을 관능검사와 Rheometer를 이용하여 비교, 분석하고 이들의 상관관계를 검토하였다. 본 실험에 의해 나타난 결과는 다음과 같다. 1. 전자렌지를 이용한 엿의 적합한 제조조건은 곡류 380g에 물 320ml를 넣고 1시간 30분동안 보온밥통내에서($60^{\circ}C$) 당화시켜 걸른 후 전자렌지내에서 찹쌀엿, 쌀엿, 조엿은 $120^{\circ}C$까지 가열하였다. 2. 당도계로 측정한 각 재료의 당화전의 당도는 11%로 모두 같았고 당화후의 당도는 각 재료간에 유의차가 있었으며(P<0.05) 찹쌀, 쌀당화액의 당도가 각각 28.8%, 28.2%로 가장 높았고 옥수수 당화액이 17.7%로 가장 낮았다. 그리고 각 당화액을 가열, 농축시킨 후 각 엿의 당도는 각 엿간에 유의차가 나타나지 않았으나 찹쌀엿이 86%로 가장 높고 옥수수엿이 82.7%로 가장 낮은 경향을 보였다. 3. pH meter로 측정한 각 재료의 당화전의 pH는 4.4로 모두 같았고 당화후의 pH는 각 재료간에 유의차가 없었으나 수수당화액이 4.7로 가장 높고 옥수수당화액이 4.3으로 가장 낮았다. 4. 관능검사에 의한 엿의 특성에 대한 평가에서 가장 바람직한 엿으로 평가를 받은 것은 찹쌀엿이었고 다음은 쌀엿, 조엿, 수수엿, 옥수수엿 순이었으며 찹쌀엿과 쌀엿간에는 유의차가 없었고 또한 조엿, 수수엿, 옥수수엿은 바람직하지 않다는 평가를 받았고 이들은 찹쌀엿, 쌀엿과는 유의적인 차이가 있었다. Rheometer에 의한 Texture 측정 결과 거의 같은 정도의 우수한 평가를 받았으므로 찹쌀엿은 쌀엿으로 대체하여 이용할 수 있으며 조엿, 수수엿, 옥수수엿은 엿제조가 가능하기는 하지만 엿의 품질에 있어서는 찹쌀엿, 쌀엿에 비해 낮았다. 그러나 실제로는 찹쌀엿, 수수엿 및 쌀엿이 주로 제조 , 이용되고 있는 경향인데 비용이 적게 들며 우수한 엿으로 평가된 쌀엿을 제조, 이용하는것이 바람직하다고 사료된다.