• 한국미생물·생명공학회지
• /
• 제46권1호
• /
• pp.18-28
• /
• 2018

DPPH를 이용한 인동덩굴 추출물의 자유라디칼 소거활성($FSC_{50}$) 측정 결과, 인동덩굴 에틸아세테이트 분획물 ($77.25{\mu}g/ml$)이 50% 에탄올 추출물($152.00{\mu}g/ml$)보다 약 2배 높은 활성을 나타내었다. Luminol 발광법을 이용한 인동덩굴 추출물의 활성산소 소거활성(총 항산화능, $OSC_{50}$) 측정 결과, 인동덩굴 에틸아세테이트 분획물($0.33{\mu}g/ml$) > 인동덩굴 50% 에탄올 추출물($1.12{\mu}g/ml$) > L-ascorbic acid ($4.95{\mu}g/ml$) 순서로 높게 나타났다. $^1O_2$으로 유도된 적혈구 파괴에 대한 세포 보호 효과(${\tau}_{50}$) 측정 결과, 인동덩굴 추출물의 농도에 의존적으로 세포 보호 효과가 나타났으나, 고농도에서는 세포 보호 효과가 감소하는 경향을 나타내었다. 인동덩굴 50% 에탄올 추출물은 $10{\mu}g/ml$의 농도(46.0 min)에서, 인동덩굴 에틸아세테이트 분획물은 $1{\mu}g/ml$의 농도(52.3 min)에서 가장 높은 세포 보호 효과를 나타내었다. 인동덩굴 추출물 및 분획물의 세포 독성 평가 결과, 본 실험에서는 $0.4-12.5{\mu}g/ml$의 농도 범위를 설정하여 세포 보호 효과를 평가하였다. 과산화수소로 유도된 각질 형성 세포인 HaCaT 세포 보호 효과는 인동덩굴 50% 에탄올 추출물 및 에틸아세테이트 분획물 $12.5{\mu}g/ml$의 농도에서 각각 70.0, 78.6%의 세포 생존율을 나타냈으며, 대조군(65%)과 비교하여 유의한 세포 보호 효과를 가지고 있음을 확인하였다. UVB를 조사한 HaCaT 세포의 세포 내 ROS 소거 활성에서 인동덩굴 50% 에탄올 추출물 및 에틸아세테이트 분획물 모두 농도 의존적으로 ROS를 소거하였으며, $12.5{\mu}g/ml$ 농도에서 각각 45.2, 63.3%의 ROS 소거율을 나타내었다. 이를 통해 인동덩굴 에틸아세테이트 분획물이 50% 에탄올 추출물보다 높은 세포 내 ROS 억제능이 있음을 확인하였다. TLC와 HPLC 크로마토그램을 이용한 인동덩굴의 에틸아세테이트 분획물의 성분 분석을 통해 caffeic acid, luteolin, apigenin, coumaric acid를 확인하였다. Caffeic acid와 luteolin의 뛰어난 환원력과 킬레이팅 작용이 인동덩굴 추출물의 활성산소 소거활성과 세포 보호 효과에 크게 기인했을 것으로 사료된다. 인동덩굴 50% 에탄올 추출물과 에틸아세테이트 분획물의 총 페놀성 화합물 및 총 플라보노이드 함량 측정 결과를 통해, 인동덩굴 에틸아세테이트 분획물이 50% 에탄올 추출물보다 많은 페놀성 화합물, 플라보노이드를 함유하고 있기 때문에 더욱 우수한 항산화 활성을 나타내었음을 확인하였다. 본 연구에서는 자외선에 의해 생성되는 다양한 ROS에 대한 인동덩굴 추출물 및 분획물의 항산화 활성을 평가하였고 이상의 결과를 통해 인동덩굴 추출물이 식물유래 천연 항산화제로서 가치가 있음을 시사하였다. 뿐만 아니라, 인동덩굴의 항산화 기능성 화장품 소재로서의 개발 가능성을 확인하였다.

• 한방재활의학과학회지
• /
• 제24권3호
• /
• pp.51-69
• /
• 2014

Objectives This study was aimed to investigate the effects of Sibjeondaebotanggamibang (SJT) on the wound-induced rats. Methods It was observed the effects of anti-oxidation and anti-inflammation by using of lipopolysaccharide (LPS)-treated RAW 264.7 cells. For the observing on SJT anti-oxidation, it needed to mesure the total amount of polyphenol, DPPH scavenging ability, ABTS scavenging ability and the value of ROS production. In order to observe on the anti-inflammation of SJT, it was mesured the value of No and Cytokine (TNF-${\alpha}$, IL-$1{\beta}$, IL-6). It needed to make a scar (around $2{\times}2cm^2$) on the top of the fascia in the back of the rats and then the rats were divided into 4 groups (n=6). Control group was not treated at all, whereas SJ group was orally medicated SJT, Terra group was per-cutaneously applied Terramycin, and SJ+Terra group was both orally medicated SJT and percutaneously applied Terramycin per day for three weeks. The size of wound was measured with Digimatic Caliper and the blood samples (WBC, neutrophil, monocyte, lymphocyte) were analyzed using Minos-ST, which were collected by cardiac puncture. The effect on inflammatory cytokine (TNF-${\alpha}$, IL-$1{\beta}$, IL-6), immunological cells in synovial fluid was measured. To measure the wound factor expressed by wounded skin sample, we extracted RNA and to investigate MMP-1,2,9 we used RT-PCR. For performing histopathological examinations, we paralyzed the rats by ether, and extracted wounded skin tissues, which were measured by H & E, and monitored on the optical microscope. Results 1. DPPH and ABTS scavenging activity of SJT was increased concentration-dependantly, and ROS scavenging activity was significantly increased (10, $100{\mu}g/ml$). 2. NO production was significantly reduced in SJT treated cells ($100{\mu}g/ml$), both TNF-${\alpha}$ and IL-6 in SJT treated cells (1, 10, $100{\mu}g/ml$), and IL-$1{\beta}$ in SJT treated cells (1, $100{\mu}g/ml$). 1. The size of wound was significantly decreasing in SJ group, Terra group, SJ+Terra group. 2. WBC was significantly reduced in SJ and SJ+Terra group, monocyte in SJ+Terra group. Neutrophil was also reduced in SJ, SJ+Terra group but meaningless. 3. TNF-${\alpha}$ and IL-6 were significantly reduced in SJ group, Terra group, SJ+Terra group, and IL-$1{\beta}$ in SJ+Terra group. 4. mRNA expression in MMP-1 was significantly reduced in SJ group. 5. Collegan production and chronic inflammation were significantly decreased in SJ group, Terra group, SJ+Terra groups. Re-epithelization on the skin in Terra group, SJ+Terra groups was decreased. Conclusions According to this in vitro experiment, Sibjeondaebotanggamibang (SJT) has the effects of anti-oxidative and anti-inflammatory. By in vivo experiment, SJT has the effects of anti-inflammatory. Moreover, the progress of recovery was found visually, heamatologically, genetically and histopathologically. In conclusion, it could be thought that SJT has effect on the treating of wound.

• 대한간호학회지
• /
• 제13권1호
• /
• pp.7-21
• /
• 1983

For the flexible and rational distribution of limited existing health resources based on measurements of individual risk, the socalled Risk Approach is being proposed by the World Health Organization as a managerial tool in maternal and child health care program. This approach, in principle, puts us under the necessity of developing a technique by which we will be able to measure the degree of risk or to discriminate the future outcomes of pregnancy on the basis of prior information obtainable at prenatal care delivery settings. Numerous recent studies have focussed on the identification of relevant risk factors as the Prior infer mation and on defining the adverse outcomes of pregnancy to be dicriminated, and also have tried on how to develope scoring system of risk factors for the quantitative assessment of the factors as the determinant of pregnancy outcomes. Once the scoring system is established the technique of classifying the patients into with normal and with adverse outcomes will be easily de veloped. The scoring system should be developed to meet the following four basic requirements. 1) Easy to construct 2) Easy to use 3) To be theoretically sound 4) To be valid In searching for a feasible methodology which will meet these requirements, the author has attempted to apply the“Likelihood Method”, one of the well known principles in statistical analysis, to develop such scoring system according to the process as follows. Step 1. Classify the patients into four groups: Group $A_1$: With adverse outcomes on fetal (neonatal) side only. Group $A_2$: With adverse outcomes on maternal side only. Group $A_3$: With adverse outcome on both maternal and fetal (neonatal) sides. Group B: With normal outcomes. Step 2. Construct the marginal tabulation on the distribution of risk factors for each group. Step 3. For the calculation of risk score, take logarithmic transformation of relative proport-ions of the distribution and round them off to integers. Step 4. Test the validity of the score chart. h total of 2, 282 maternity records registered during the period of January 1, 1982-December 31, 1982 at Ewha Womans University Hospital were used for this study and the“Questionnaire for Maternity Record for Prenatal and Intrapartum High Risk Screening”developed by the Korean Institute for Population and Health was used to rearrange the information on the records into an easy analytic form. The findings of the study are summarized as follows. 1) The risk score chart constructed on the basis of“Likelihood Method”ispresented in Table 4 in the main text. 2) From the analysis of the risk score chart it was observed that a total of 24 risk factors could be identified as having significant predicting power for the discrimination of pregnancy outcomes into four groups as defined above. They are: (1) age (2) marital status (3) age at first pregnancy (4) medical insurance (5) number of pregnancies (6) history of Cesarean sections (7). number of living child (8) history of premature infants (9) history of over weighted new born (10) history of congenital anomalies (11) history of multiple pregnancies (12) history of abnormal presentation (13) history of obstetric abnormalities (14) past illness (15) hemoglobin level (16) blood pressure (17) heart status (18) general appearance (19) edema status (20) result of abdominal examination (21) cervix status (22) pelvis status (23) chief complaints (24) Reasons for examination 3) The validity of the score chart turned out to be as follows: a) Sensitivity: Group $A_1$: 0.75 Group $A_2$: 0.78 Group $A_3$: 0.92 All combined : 0.85 b) Specificity : 0.68 4) The diagnosabilities of the“score chart”for a set of hypothetical prevalence of adverse outcomes were calculated as follows (the sensitivity“for all combined”was used). Hypothetidal Prevalence : 5％ 10％ 20％ 30％ 40％ 50％ 60％ Diagnosability : 12% 23% 40% 53% 64% 75% 80%.

• 동의신경정신과학회지
• /
• 제31권1호
• /
• pp.1-12
• /
• 2020

Objectives: The purpose of this study was to evaluate the reliability and validity of the instrument on pattern identification for insomnia (PIT-Insomnia) and verify the correlation between PIT-Insomnia and psychological tests. Methods: Two evaluators examined the pattern identification of the participants who met insomnia disorder diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorder, Fifth Edition (DSM-5) and took the Insomnia Severity Index (ISI) score over 15 once manually and twice using the PIT-Insomnia to measure the inter-rater and test-retest reliability. We also conducted the following surveys: the Pittsburgh Sleep Quality Index (PSQI), the Korean version of Beck's depression inventory (K-BDI), the Korean version of the State-Trait Anxiety Inventory (STAI-K), the Korean Symptom checklist-95 (KSCL-95), and the EuroQol-5 dimension (EQ-5D), to measure concurrent validity and correlation between the PTI-Insomnia and psychological tests. Results: 1. The test-retest reliability analysis of the pattern identification results showed moderate agreement, and test-retest reliability analysis of each pattern identification score showed agreements from poor to moderate. 2. The inter-rater reliability analysis of the pattern identification results via manual showed slight agreement, when analysis was performed with calibration, the inter-rater reliability analysis of the pattern identification results via manual showed fair agreement. 3. The concordance analysis between results via manual and the PIT-Insomnia showed poor agreement, when the analysis was performed with calibration, concordance analysis showed fair agreement. 4. The concordance analysis between the PIT-Insomnia and the PSQI showed positive linear correlation. 5. The concordance analysis between the PIT-Insomnia and the PSQI, K-BDI, STAI-K, KSCL-95, and EQ-5D showed that non-interaction between the heart and kidney have positive linear correlation with the K-BDI, anxiety item of KSCL-95, dual deficiency of the heart-spleen have positive linear correlation with somatization item of KSCL-95, paranoia item of KSCL-95, heart deficiency with timidity have positive linear correlation with stress vulnerability item of KSCL-95, parania item of KSCL-95, phlegm-fire harassing the heart have positive linear correlation with K-BDI, paranoia item of KSCL-95, depressed liver qi transforming into fire have positive linear correlation with the anxiety item of KSCL-95, parania item of KSCL-95, all pattern identification have negative linear correlation with EQ-5D. Conclusions: The PIT-Insomnia has moderate agreement of reliability and reflects the severity of insomnia since it has some concurrent validity with the PSQI. There are some correlations between the PTI-Insomnia with specific psychological tests, so we could suggest it can be used appropriately in the clinical situation.

• 한국농림기상학회지
• /
• 제19권3호
• /
• pp.153-163
• /
• 2017

데이터 처리 속도는 예보 능력과 관련이 있다. 최신의 입력 자료를 이용한 예측 데이터의 고속 생산은 신속한 대처를 가능하게 한다. 또한 알고리즘 작성, 계산, 결과 평가, 알고리즘 개선으로 이어지는 순환 구조를 원활하게 할 뿐만 아니라 오류 발생시 빠른 시간 내에 복구할 수 있게 하는 등 매우 중요한 요소이다. 현재의 조기경보 시스템은 매 계산 주기 마다 섬진강 유역의 10개 시군에 대해 30미터 해상도의 격자형 자료를 400개 이상 생성하고 있으며(중간 데이터 포함) 최대 9일까지 예보되는 자료를 포함할 경우 600개 이상이다. 이는 전국을 30미터 해상도로 약 45개를 생성하는 계산양과 비슷하다. 또한 14,000여개의 필지에 대한 구역 통계와, 각 래스터의 평균, 최대, 최소 등의 통계자료 생성도 함께 수행 해야 한다. 이와 같은 대량의 데이터를 한정된 시간 내로 처리하기 위한 몇 가지 기법을 적용하여 적용하였으며, 아직 적용은 못하였으나 가능성의 여부를 평가해 보는 것으로 본 연구를 진행하였다. 그 결과 앞서 제시된 래스터 캐시, NFS 캐시, 분산 처리를 모두 적용할 경우 데이터 처리 시간을 1/8로 단축 시킬 수 있음이 확인되었다. 또한 GPU를 이용한 연산을 적용할 경우 일부 모듈에 대해 매우 큰 폭으로 수행 시간을 단축 시킬 수 있음을 확인하였다. 다만 캐시를 위한 추가적인 디스크, GPU라는 별도의 하드웨어, 추가된 하드웨어 지원을 위한 고출력 전원 장치와 이에 따른 UPS (Uninterruptible power supply, 무정전 전원공급 장치)까지 상대적으로 높은 사양으로 준비해야 하는 비용적인 문제가 발생할 수 있다. 본 연구에서 제시한 네 가지 기법 중 세 가지는 계산 서버 추가를 통한 수평적 성능 확장에 관한 것이다. 하지만 서버의 추가가 처리 속도 향상으로 이어지지 않음은 물론 오히려 저하시키는 경우가 있다. 본 연구에서는 특정 시간 내로 작업을 완료 시키지 못하면 해당 작업을 반환하여 다른 서버가 처리하는 간단한 방식을 이용한다. 하지만 이런 문제를 지속적으로 발생시키는 계산 서버가 발견된다면 정해진 기준에 따라 계산 작업에서 완전히 퇴출 시켜야 성능 향상에 도움이 된다. 따라서 처리 속도에 대한 정확한 원인을 검사하고 이를 실시간으로 반영할 수 있는 기법이 필요하다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제26권9호
• /
• pp.1320-1328
• /
• 2013

Three experiments were conducted to evaluate the ME value, standardized ileal digestibility (SID) of amino acids (AA) of fish meal, and the effects of single cell protein (Prosin and Protide) replacing fish meal in diet on growth performance, nutrient digestibility and intestinal morphology in weaned piglets. In Exp. 1, twenty-four barrows with initial BW of $30.8{\times}2.6kg$ were allotted to one of four dietary treatments. Diet 1 contained corn as the only energy source. The other three diets replaced 20% of the corn in diet 1 with one of the three protein feeds (fish meal, Prosin and Protide), and the DE and ME contents were determined by difference. In Exp. 2, eight barrows (initial BW of $25.6{\pm}3.2kg$) were fitted with ileal T-cannulas and allotted to a replicated $4{\times}4$ Latin square design. Three cornstarch-based diets were formulated using each of the protein feeds as the sole source of AA. A nitrogen-free diet was also formulated to measure endogenous losses of AA. In Exp. 3, one hundred and eighty piglets (initial BW of $7.95{\pm}1.59kg$) weaned at $28{\times}2d$ were blocked by weight and assigned to one of five treatments for a 28-d growth performance study, each treatment was fed to six pens with six pigs (three barrows and three gilts) per pen. The five treatments consisted of the control group (CON), which was a corn-soybean meal diet containing 5% fish meal, and the other four treatments, which replaced a set amount of fish meal with either Prosin (2.5% or 5%) or Protide (2.5% or 5%). The diets were formulated to provide same nutrient levels. The results showed that on a DM basis, both of the DE and ME contents were lower in Prosin and Protide than that of fish meal (p<0.05). The SID of CP and all essential AA were greater in fish meal than in Prosin and Protide (p<0.05). The pigs fed CON diet had greater weight gain and lower feed conversion rate (FCR) than pigs fed 5% Prosin and 5% Protide diets (p<0.05). The digestibility of CP was greater in pigs fed CON, 2.5% Prosin and 2.5% Protide diets than the pigs fed 5% Prosin and 5% Protide diets (p<0.05). Villus height in jejunum and ileum, and villus height to crypt depth ratio in the jejunum were higher (p<0.05) in pigs fed CON, 2.5% Prosin and 2.5% Protide diets compared with the 5% Prosin and 5% Protide diets. Pigs fed CON diet had greater villus height to crypt depth ratio in the ileum than the pigs fed 5% Prosin and 5% Protide diets (p<0.05). In conclusion, although Prosin and Protide contained lower ME content and SID of AA than fish meal, Prosin and Protide replacing 50% of fish meal in diet with identical nutrient levels could obtain similar performance, nutrient digestibility and intestinal morphology in weaned pigs.

• 한국산학기술학회논문지
• /
• 제18권9호
• /
• pp.436-443
• /
• 2017

최근, 지구온난화 등의 문제로 인해 새로운 에너지 기술의 개발이 화제가 되고 있다. 중규모 이상의 출력을 얻도록 최적화된 태양광 및 태양열, 풍력 발전과 같은 신재생에너지 기술과 다르게 에너지 하베스팅기술은 출력전력이 매우 작아 크게 주목받지 못하고 있다. 하지만 최근 모바일 산업이 활성화 되면서 에너지 하베스팅기술의 활용가치가 재평가 받고 있다. 또한, 최대전력점 추적방식기술 역시 활발히 연구가 이루어지고 있다. 본 논문에서는 일정한 저항부하를 위한 열전모듈의 새로운 최대전력점추적 제어방식을 제안한다. 열전 모듈(이하 TEM: Thermoelectric Module)의 V-I곡선특성과 내부저항을 분석하고. 기존의 MPPT제어방식을 비교하였다. P&O(Perturbation and Observation)제어방식은 전압, 전류를 측정하기위한 센서 2개를 사용해야하기 때문에 CV제어방식보다 경제성이 떨어지지만 보다 정확히 MPP를 찾는다는 장점을 가진다. CV(Constant Voltage)제어방식은 전압센서 1개만 사용하기 때문에 경제적인 측면에서는 P&O제어방식보다 뛰어나지만, MPP가 정확히 못하다는 단점을 가지고 있다. 본 논문에서는 두 제어방식의 장점만을 가지고 TEM의 최대전력점(MPP)을 추적하도록 설계하였다. 제안된 MPPT 제어 방식은 PSIM 프로그램을 이용한 모의실험으로 확인하였으며, 하드웨어제작을 통해 제안된 MPPT제어 방식을 검증하였다.

• 대한간호학회지
• /
• 제15권3호
• /
• pp.5-20
• /
• 1985

The purpose of this study was to assess the value-of post-operative treatment in terms of nursing care in the allevation of pain. More specifically, the effects of supportive touch and patient education were examined. On the date before each patient's operation, the Bevels of anxiety, depression and affiliation were examined. The post-operative treatment was adminis. tered after an initial measurement of the patient's fain, according to the experimental category for the three days following the operation. On the final day, the level of anxiety and depression were again measured. The subjects of this study were 138 patient from the general surgical and gynecological wards in H university Hospital in Seoul. The study was conducted over a three-month period from June 24, 1984 to September 18, 1984. All patients had undergone laparatomies. Various standard instruments were used to measure the pain, anxiety, depression and affiliation levels. for pain, 5 grate Simple Descriptive Scale, and the Mclachlan four-range Observational Pain Scale were employed. For anxiety and depression, respectively the Spielberger State Anxiety Inventory and Beck Depression Inventory (B.D.I.) were used. Lastly, the affiliation was determined by the Mehrabian Affiliation Scale. The outcome of the research was as follows: 1. The first hypothesis concerning the existence of lower pain levels of Experimental Group A and Experimental Group B than the pain levels of Control Croup C was not supported. 2. The second hypothesis concerning the existence if lower anxiety levels of Experimental Group A and Experimental Group B than the anxiety levels of Control Group C was supported at the level of F=3.58 (p=.03). 3. The third hypothesis concerning the existence of lower depression levels of Experimental Group A and Experimental Group B than the depression levels of Control Group C was not supported. 4. The fourth hypothesis concerning the existence of different levels of pain in accordance with the levels of affiliation in Experimental Group A was not supported. 5. A positive correlation did exist between pain and anxiety after surgery (r=.34, p=.0001). Thus, the fifth hypothesis was supported. 6. A positive correlation did exist between pain and depression following surgery(r=.36, p=.0001). Thus, the sixth hypothesis was supported. Based on the above results, it was found that supportive touch and patient education either through human sources or via tape recorder do influence the anxiety of a patient after surgery, that a Positive correlation between pain, anxiety and deparession exist, that affiliation does not alter the influence of supportive touch, and that the graph on which pain levels were depicted indicates the possibility of development even if the effects of supportive touch did not reach a meaningful level. Thus it can be concluded that patient education, regardless of its form, is essential for the patient after surgery and that supportive touch, when reasonably modified and supplemented, can be an effective method of alleviating pain.

• Asian-Australasian Journal of Animal Sciences
• /
• 제28권1호
• /
• pp.86-94
• /
• 2015

This experiment was conducted to evaluate the chemical composition and amino acid (AA) digestibility of sunflower seed meal (SFSM) and to use this data to develop prediction equations for estimating AA digestibility for growing pigs. Ten SFSM were collected from five provinces in China. Twelve barrows ($38.8{\pm}4.6kg$), fitted with ileal T-cannula were allotted into two $6{\times}6$ Latin square designs. Each of six experimental periods comprised a 5-d adaption period followed by a 2-d collection of ileal digesta. The ten test diets contained 50% SFSM as the sole source of AA. Another nitrogen-free diet was used to measure the basal endogenous losses of crude protein (CP) and AA. Chromic oxide (0.3%) was used as an inert marker in each diet. There was considerable variation (CV>10%) among the ten SFSM in chemical composition (dry matter [DM]). The concentration of CP and ether extract (EE) ranged from 29.33% to 39.09% and 0.88% to 11.33%, respectively. Crude fibre (CF), neutral detergent fibre and acid detergent fibre ranged from 21.46% to 36.42%, 38.15% to 55.40%, and 24.59% to 37.34%, respectively. There was variation among the ten SFSM in apparent ileal digestibility (AID) and standardized ileal digestibility (SID) for lysine and threonine, which ranged from 63.16 to 79.21 and 55.19% to 72.04% for AID and 67.03% to 82.07% and 61.97% to 77.01% for SID, respectively. The variation in CP and methionine ranged from 60.13% to 74.72% and 74.79% to 88.60% for AID and 66.70% to 79.31% and 77.16% to 90.27% for SID, respectively. Methionine was a good indicator to predict AA digestibility. These results indicate that conventional chemical composition of SFSM was variable (CV>10%) among the ten SFSM (DM). The results of AID, SID and prediction equations could be used to evaluate the digestibility of SFSM in growing pigs.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 2010년도 한국우주과학회보 제19권1호
• /
• pp.26.4-27
• /
• 2010

The main payload of STSAT-3 (Science and Technology Satellite 3), MIRIS (Multipurpose InfraRed Imaging System) is the first Korean infrared space mission to explore the near-infrared sky with a small astronomical instrument, which is being developed by KASI. The 8-cm passively cooled telescope with a wide field of view (3.67 deg. $\times$ 3.67 deg.) will be operated in the wavelength range from 0.9 to $2{\mu}m$. It will carry out wide field imaging and the emission line survey. The main purposes of MIRIS are to perform the Cosmic Infrared Background (CIB) observation at two wide spectral bands (I and H band) and to survey the Galactic plane at $1.88{\mu}m$ wavelength, the Paschen-$\alpha$ emission line. CIB observation enables us to reveal the nature of degreescale CIB fluctuation detected by the IRTS (Infrared Telescope in Space) mission and to measure the absolute CIB level. The Pashen-$\alpha$ emission line survey of Galactic plane helps us to understand the origin of Warm Ionized Medium (WIM) and to find the physical properties of interstellar turbulence related to star formation. Here, we also discuss the observation plan with MIRIS.