• Journal of Korean Society of Steel Construction
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• v.22 no.4
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• pp.345-354
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• 2010

This paper presents an experimental investigation of the structural performance of a large-span girder bridge with an under-tension system. Typical long-span structures with beam and girder members have greater structural member depths and sizes to carry the moment and deflection. An under-tension system can be an effective structural system, as it allows the cables to resist some portions of the vertical loadings and deflections. To evaluate the serviceability and ultimate strength of the under-tension system, two $10m{\times}2.4m$ experimental under-tension systems were built and tested. One was developed with an H-beam section, and the other was made with a PF500 section that had the advantages of fast construction and lower construction cost. In the test, the maximum deflections at the mid-point of both beams were effectively reduced using under-tension systems. Also, the increased tension forces in the cable reduced the deflections. The PF500 members, which had a new shape and were developed using the module systems, performed better than the typical H-beam sections in terms of the deflections and ultimate strength.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.23 no.6
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• pp.1526-1537
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• 1998

The split-screen function on the multipoint control unit(MCU) which is usually using processing method based on pixel domain has many problems for manipulating the video signal in real-time. Although the researches and the developements to cope ith such problems are processing, these have too complex architecture to implement and are limited to method for H.261 video signal. In this paper, we propose a new mechanism for split-screen that can actually apply to ISO/IEC MPEG video standard. The new method that is proposed in this paper do the processes in complete compression domain, thus it is suitable for the application of real-time multipoint multimedia communication service. By simple interpreting and manipulating the MPEG video element stream, the split-screen functional module can be implemented easily and the result of the procedures does not accompany image degradation at all. Finally, the complexity of implementation, the aspect for processing delay and the loss of image quality as compared to that resulting in the case of applying the previous split-screen method has been investigated. And it is confirmed that the proposed mechanism has a significant advantage as a split-screen method.

• Journal of the Korean Society for Precision Engineering
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• v.15 no.2
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• pp.124-133
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• 1998

This paper describes a research work of developing a computer-aided design of blanking and piercing for irregular-shaped sheet metal products. An approach to the development of compact and practical CAB system is based on the knowledge-based rules. Knowledge for the CAD system is formulated from plasticity theories, experimental results and the empirical knowledge of field experts. The system has been written in AutoLISP on the AutoCAD with a personal computer. Based on knowledge-based rules, the system, STRT-DES, is designed by considering several factors, such as complexities of blank geometry and punch profile, availability of press equipment and standard parts, utilization ratio which minimizes the scrap in a single or a pairwise operation, bridge width, grain orientation and design requirements which maximize the strength of the part when subsequent bending is involved. This system checks a forming feasibility with both internal and external features, a dimension of blanked hole, and a corner and a fillet radius for irregualrly shaped sheet metal products. Therefore this system can carry out a die design for each process which is obtained from results of an automated blank layout drawing with a best utilization ratio for irregular shape of product that was successful in production feasibility check module and those of an automated strip layout drawing and generate part drawings and the assembly drawing of die set in graphic forms.

• Molecules and Cells
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• v.41 no.9
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• pp.842-852
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• 2018

Notch signaling is an evolutionarily conserved pathway and involves in the regulation of various cellular and developmental processes. Ligand binding releases the intracellular domain of Notch receptor (NICD), which interacts with DNA-bound CSL [CBF1/Su(H)/Lag-1] to activate transcription of target genes. In the absence of NICD binding, CSL down-regulates target gene expression through the recruitment of various corepressor proteins including SMRT/NCoR (silencing mediator of retinoid and thyroid receptors/nuclear receptor corepressor), SHARP (SMRT/HDAC1-associated repressor protein), and KyoT2. Structural and functional studies revealed the molecular basis of these interactions, in which NICD coactivator and corepressor proteins competitively bind to ${\beta}-trefoil$ domain (BTD) of CSL using a conserved ${\varphi}W{\varphi}P$ motif (${\varphi}$ denotes any hydrophobic residues). To date, there are conflicting ideas regarding the molecular mechanism of SMRT-mediated repression of CSL as to whether CSL-SMRT interaction is direct or indirect (via the bridge factor SHARP). To solve this issue, we mapped the CSL-binding region of SMRT and employed a 'one- plus two-hybrid system' to obtain CSL interaction-defective mutants for this region. We identified the CSL-interaction module of SMRT (CIMS; amino acid 1816-1846) as the molecular determinant of its direct interaction with CSL. Notably, CIMS contains a canonical ${\varphi}W{\varphi}P$ sequence (APIWRP, amino acids 1832-1837) and directly interacts with CSL-BTD in a mode similar to other BTD-binding corepressors. Finally, we showed that CSL-interaction motif, rather than SHARP-interaction motif, of SMRT is involved in transcriptional repression of NICD in a cell-based assay. These results strongly suggest that SMRT participates in CSL-mediated repression via direct binding to CSL.