• Proceedings of the KSR Conference
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• 2008.06a
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• pp.1227-1232
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• 2008

High-speed train of push-pull type called as G7 train has been developed and chosen as the model of KTX-II which will be operated on Honam Line nexr year. However, the EMU-type high-speed train appeared to be the recent trend that foreign markets have shown. Also, in the near future, a great number of new train sets are needed to accommodate the increased passengers in our country. Thus, development of the high-speed EMU was decided, planned, and started. In the development, included were almost all fundamental key technologies such as noise and vibration reduction in a passenger cabin, running characteristics, aerodynamic analysis, crashworthiness evaluation, EMI/EMC analysis, design of the cooling system for the propulsion control system, enhanced performance of transformer and switching converters, synchronous traction motor with permanent magnets, new design of front nose and ergonomic interiors, application of advanced information technology(IT) and smart sensors and the cost reduction of construction of railway bridges, etc. Each key technologies are carried out as sub-project independently but under the supervision of a project. The project will develop the high advanced level of technologies and provide necessary know-why's and support the team in charge of the development of the high-speed EMU, Hyundai Rotem Co. Ltd. The high-speed EMU will be successfully developed with the support of the project.

• Journal of Pharmacopuncture
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• v.3 no.1
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• pp.1-19
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• 2000

To study anti-cancer effect and molecular biological mechanism of bee venom for aqua-acupuncture, the effects of bee venom on cell viability and apoptosis were analyzed using MTT assay, tryphan blue assay, $[^3H]$thymidine release assay, flow cytometric analysis, and activity of caspase-3 protease activity assay. To explore whether anti-cancer effects of bee venom are associated with the transcriptional control of gene expression, quantitative RT-PCR analysis of apoptosis-related genes was performed. The obtained results are summarized as follows: 1. The MTT assay demonstrated that cell viability was decreased by bee venom in a dose-dependant manner. 2. Significant induction of apoptosis was identified using tryphan blue assay, $[^3H]$thymidine release assay, and flow cytomet1 ric analysis of sub $G_1$ fraction. 3. In analysis of caspase-3 protease activity, the activity had increased significantly, in a dose-dependant manner. 4. Quantitative RT-PCR analysis of the apoptosis-related genes showed that Bcl-2 and Bcl-$X_L$ were down-regulated whereas Bax was up-regulated by bee venom treatment.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.598-603
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• 2005

Recently, the advanced industries using micro parts are rapidly growing. The appearance of ultra-precision feed mechanism and the development of control system make it possible to process parts in sub millimeter scale by mechanical methods. Micro endmilling is one of the prominent technology that has wide spectrum of application field ranging from macro parts to micro products. So, micro stairs have been trying to cut by using high revolution air turbine spindle and micro-endmill, and studying for magnitude of cutting force. This investigation deals removal characteristics of burr generated by micro endmilling process. Also, decreasing of burr is significant problem in making smooth and precise parts in micro endmilling. In micro endmilling, the material removal rate(MRR) and cutting forces are very small. This paper presents an investigation on the machining characteristics for micro stairs by using ultrahigh-speed air turbine spindle in machining.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2000.11c
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• pp.715-721
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• 2000

In this research, rule and neuro net based boundary extraction algorithm was developed. Extracting boundary of the interest, lean tissue, is essential for the quality evaluation of the beef based on color machine vision. Major quality features of the beef are size, marveling state of the lean tissue, color of the fat, and thickness of back fat. To evaluate the beef quality, extracting of loin parts from the sectional image of beef rib is crucial and the first step. Since its boundary is not clear and very difficult to trace, neural network model was developed to isolate loin parts from the entire image input. At the stage of training network, normalized color image data was used. Model reference of boundary was determined by binary feature extraction algorithm using R(red) channel. And 100 sub-images(selected from maximum extended boundary rectangle 11${\times}$11 masks) were used as training data set. Each mask has information on the curvature of boundary. The basic rule in boundary extraction is the adaptation of the known curvature of the boundary. The structured model reference and neural net based boundary extraction algorithm was developed and implemented to the beef image and results were analyzed.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.07a
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• pp.157-160
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• 2001

Three sets of ZnO ceramic devices (reference samples with Matsuoka\`s composition; added 7o MgO, A1$_2$O$_3$, SiO$_2$) have been prepared by the conventional mixed oxide route. These additives were determined by the factors of valences and ionic radiuses. DC accelerated degradation test was performed for analysis of degradation characteristics versus the various additives. The conditions of DC degradation test were 115${\pm}$2$^{\circ}C$ for 12h. Using XRD and SEM, the Phase and microstructure of samples were analyzed respectively. E-J analysis was used to determine ${\alpha}$. Frequency analysis was accomplished to understand the relationship between R$\sub$g/ and $R_{b}$ with the electric stress at the equivalent circuit.

• Journal of Magnetics
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• v.13 no.1
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• pp.34-36
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• 2008

For the measurement of the magnetic field distribution with high spatial resolution and high accuracy, the magnetic field sensing probe must be non-magnetic, but the MFM probe and sub-millimeter-meter size Hall probe use a ferromagnetic tip and block, respectively, to increase the sensitivity. To overcome this drawback, we developed a micro-size search coil magnetometer which consists of a single turn search coil, Terfenol-D actuator, scanning system, and control software. To reduce the noise generated by the stray ac magnetic field of the actuator driving coil, we employed an even function $\lambda$-H magnetostriction curve and lock-in technique. Using the developed magnetometer, we were able to measure the magnetic field distribution with a magnetic field resolution of 1 mT and spatial resolution of $0.1mm{\times}0.2mm$ at a coil vibration frequency of 1.8 kHz.

• Biomolecules & Therapeutics
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• v.16 no.1
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• pp.1-8
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• 2008

Mitochondria are important sensor of apoptosis. $H_2O_2-induced$ cell death rate was enhanced by serum deprivation. In this study, we investigated whether serum deprivation using 0.5 or 3 % FBS induces apoptotic cell death through mitochondrial enzyme activation as compared to 10 % FBS. Apoptotic cell death was observed by chromosome condensation and the increase of sub-G0/G1 population. Serum deprivation reduced cell growth rate, which was confirmed by the decrease of S-phase population in cell cycle. Serum deprivation significantly increased caspase-9 activity and cytochrome c release from mitochondria into cytosol. Serum deprivation-induced mitochondrial changes were also indicated by the increase of ROS production and the activation of mitochondrial enzyme, succinate dehydrogenase. Mitochondrial enzyme activity increased by serum deprivation was reduced by the treatment with rotenone, mitochondrial electron transport inhibitor. In conclusion, serum deprivation induced mitochondrial apoptotic cell death through the elevation of mitochondrial changes such as ROS production, cytochrome c release and caspase-9 activation. It suggests that drug sensitivity could be enhanced by the increase of mitochondrial enzyme activity in serum-deprived condition.

• Journal of Korean Public Health Nursing
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• v.26 no.1
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• pp.91-100
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• 2012

Purpose: The purpose of this study was to examine the effects of microteaching for student health educators. Methods: Subjects included 43 students in the nursing department of "H" university. In order to measure the degree of self-efficacy and speech anxiety at pre-treatment and post-treatment, subjects in the experimental group underwent training in microteaching. Results: No significant difference of variance in self-efficacy and speech anxiety was observed between subjects in the experimental group and those in the control group. However, self-confidence, a sub-domain of self-efficacy, showed a significant increase from pretest to post-test. In addition, speech anxiety measured during the post-test showed improvement, when compared with that of the pretest. Conclusion: Findings of this study provide preliminary evidence that microteaching may result in improved speech behavior.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.79.3-80
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• 2003

The effects of anonaine, an aporphine isoquinoline alkaloid, on dopamine biosynthesis and L-DOPA-induced neurotoxicity in PC12 cells were investigated. Treatment of PC12 cells with 0.05 ${\mu}$M anonaine showed a significant inhibition of dopamine content. The IC$\sub$50/ value of anonaine was 0.05 ${\mu}$M. Under the same conditions, 0.05 ${\mu}$M anonaine also inhibited tyrosine hydroxylase (TH) activity at 24 h (62.0% inhibition of the control level). TH mRNA levels were also decreased by the treatment with anonaine. (omitted)

• Clean Technology
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• v.25 no.4
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• pp.324-330
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• 2019

The selective catalytic reduction system is a highly effective technique for the denitrification of the flue gases emitted from the industrial facilities. The distribution of mixing ratio between ammonia and nitrogen oxide at the inlet of the catalyst layers is important to the efficiency of the de-NOx process. In this study, computational analysis tools have been applied to improve the uniformity of NH₃/NO molar ratio by controlling the flow rate of the ammonia injection nozzles according to the distribution pattern of the nitrogen oxide in the inlet flue gas. The root mean square of NH₃/NO molar ratio was chosen as the optimization parameter while the design of experiment was used as the base of the optimization algorithm. As the inlet conditions, four (4) types of flow pattern were simulated; i.e. uniform, parabolic, upper-skewed, and random. The flow rate of the eight nozzles installed in the ammonia injection grid was adjusted to the inlet conditions. In order to solve the two-dimensional, steady, incompressible, and viscous flow fields, the commercial software ANSYS-FLUENT was used with the k-𝜖 turbulence model. The results showed that the improvement of the uniformity ranged between 9.58% and 80.0% according to the inlet flow pattern of the flue gas.