• Title/Summary/Keyword: Gynecology department

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Supernumerary ovary on recto-sigmoid colon with associated endometriosis

  • Lim, Chul Kwon;Kim, Hee Jin;Pack, Joon Sook;Ha, Joong Gyu;Yang, Yun Seok;Lee, Hye Kyung;Kim, Seung Hyun
    • Obstetrics & gynecology science
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    • v.61 no.6
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    • pp.702-706
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    • 2018

  • A supernumerary ovary is a rare gynecological anomaly, and is usually excised due to its malignant transformation potential. We report a case of a supernumerary ovary and endometriosis situated on the anterior rectosigmoid colon. When laparoscopy was conducted, a firm, 5-cm mass was discovered on the anterior rectosigmoid colon along with normal ovaries. In this case, the discovery of a supernumerary ovary implied the presence of endometriosis. It is unusual for endometriosis and a supernumerary ovary to exist simultaneously.

  • https://doi.org/10.5468/ogs.2018.61.6.702 인용

Split hand/foot malformation with long-bone deficiency and BHLHA9 duplication: A prenatal diagnosis report

  • Cho, In Ae;Park, Ji Kwon;Baek, Jong Chul;Ha, A Na;Kang, Min Young;Lee, Jae Ik;Park, Ji Eun;Shin, Jeong Kyu;Choi, Won Jun;Lee, Soon Ae;Lee, Jong Hak;Paik, Won Young
    • Journal of Genetic Medicine
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    • v.12 no.2
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    • pp.123-127
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    • 2015

  • Distal limb deformities are congenital malformations with phenotypic variability and high genetic heterogeneity. Split hand/foot malformation, also known as ectrodactyly, is a congenital limb malformation characterized by a defect of the central rays of the hands and/or feet. Split hand/foot malformation with long-bone deficiency (SHFLD) is a rare condition related to a 17p13.3 duplication. Recently, genomic duplications encompassing BHLHA9 have been associated with SHFLD. We report a case of SHFLD presenting with campomelia of the right femur, bilateral agenesis of fibulae, bilateral club feet, and oligosyndactyly of the hands and feet, that was associated with a 17p13.3 duplication, as determined prenatally using array comparative genomic hybridization.

  • https://doi.org/10.5734/JGM.2015.12.2.123 인용 PDF KSCI

Isotretinoin exposure in pregnant women in Korea

  • Kim, Nae Ry;Yoon, So Ra;Choi, June Seek;Ahn, Hyun Kyong;Lee, So-Young;Hong, Dal Soo;Yun, Jeong Sup;Hong, Seong Yeon;Kim, Yoon Ha;Han, Jung Yeol
    • Obstetrics & gynecology science
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    • v.61 no.6
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    • pp.649-654
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    • 2018

  • Objective Isotretinoin is a notorious teratogen otherwise used for the treatment of acne vulgaris. Some countries, including those in North America and the European Union, implemented the pregnancy prevention program (PPP); however, no PPP has yet been established in South Korea. So the aim of this study was to evaluate the rate of pregnant women exposed to isotretinoin among the callers of the Korean Mother Safe Counseling Center. Methods This is a prospective cohort study. We evaluated the demographic characteristics, obstetric history, and isotretinoin exposure of pregnant women based on the mother safe registry from April 2010 to July 2016. Results Among 22,374 callers, 650 (2.9%) pregnant women were exposed to isotretinoin. The mean age was $29.0{\pm}4.4$ years in the isotretinoin-exposed group and $32.0{\pm}4.2$ years in the unexposed group (P<0.001). Moreover, the incidence of pregnancies within 30 days after isotretinoin discontinuation or during isotretinoin intake was 78.9% (513/650). The median duration of isotretinoin exposure was 18 (1-4,231) days. Furthermore, from 2011 to 2015, the incidence of isotretinoin exposure was $2.9{\pm}1.2$ pregnancies per 10,000 births in South Korea. Conclusion Approximately 80% of pregnant women are exposed to isotretinoin within the recommended 30 days of contraception or during pregnancy. Therefore, the PPP has to be established in South Korea.

  • https://doi.org/10.5468/ogs.2018.61.6.649 인용