• Title/Summary/Keyword: Gwang Ju

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Antibacterial and Antioxidant Activities of Solvent Extracts from Different Parts of Hagocho (Prunella vulgaris) (하고초 부위별 용매추출물의 항균 및 항산화 활성)

  • Seo, Jong-Kwon;Kang, Min-Jung;Shin, Jung-Hye;Lee, Soo-Jung;Jeong, Hey-Gwang;Sung, Nak-Ju;Chung, Young-Chul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.10
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    • pp.1425-1432
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    • 2010
  • This study was designed to investigate the effects of antioxidant and antibacterial activities of water, ethanol and methanol extracts from root, stem and flower stalk of Hagocho (Prunella vulgaris). The solvent extract yields from root were higher than those from stem and flower stalk, and water extract showed the highest extraction yield against ethanol and methanol extracts. The contents of total phenolic and flavonoid in ethanol extract were significantly higher in stem extract compared with those of root and flower stalk. In the case of water and methanol extracts, however, the contents were the highest in flower stalk. The electron donating ability and reducing power in all test groups were significantly increased in a dose-dependent manner, and antioxidant activities were the highest in methanol extract. In extracts from different parts of Hagocho, the antioxidant activity was the highest in flower stalk followed by stem and root. ABTS radical scavenging ability of water and methanol extracts was above 50% at $100\;{\mu}g/mL$ concentration. Antibacterial activities did not show significant differences depending on parts of Hagocho. However, antibacterial activity of ethanol extract was higher than those of other extracts.

Study on Relationship between Meridian Muscles and Modern Manual Therapy centered on Positional Release Therapy and Muscle Energy Techniques (자세이완기법과 근에너지기법을 중심으로 한 경근(經筋)과 현대 도수치료술의 상관성 연구)

  • Cha, Sang Ju;Im, Chae-Gwang;Kim, Kwang Joong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.5
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    • pp.630-640
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    • 2012
  • Recently, the range of meridian muscle has expanded to muscular membranes, tendons and sinews as well as muscles, comprehending the modern manual therapy and its theories. So, in this study, the movement of body is explained through the assignment of meridian muscles into 3 Yins and 3 Yangs, and the modern manual therapy is understood with body's movement principles rather than with simple muscular movements. For this, the ground that the meridian muscles can expand to muscular membranes, tendons and sinews is researched in newest papers and studies rather than in the conventional studies that have analyzed the meridian muscles just in anatomic viewpoints. And, to find out how it can be applied to the actual clinic, its relationship with modern manual therapies such as Positional Release Therapy and Muscle Energy Techniques which are in the spotlight lately is also researched, getting the following results: Modern manual therapy is to keep the mutual balance of Yin-Yang meridian muscles after all and secure the stability of body to relieve the pains due to the stagnation of energy and blood. In the main body, they can be allotted into the opening of Great Yang/Great Yin, the closing of Bright Yang(陽明)/Small Yin, and the pivoting of Small Yang/Growing Yin (厥陰). The bending and stretching of meridian muscles as well as the movement of body can be explained according to the principle of opening, closing and pivoting. When the body is divided into 3 Yins and 3 Yangs, the viewpoint of Yin-Yang-Inside-Outside can be applied to the protagonist and antagonist muscles, giving a theoretic basis to the modern manual therapy. In the process to understand Positional Release Therapy and Muscle Energy Techniques in the viewpoint of Meridian Muscle, it turned out that the meridian muscle theory of Oriental Medicine which used to be known only in documents can well explain the movement mechanism of human body. The stress reaction through the reciprocal inhibition in Positional Release Therapy and Muscle Energy Techniques can also be understood with Yin-Yang-Inside-Outside.

The Effect of SNAGs and Biofeedback Training on the Integrative Propriocepcion and Function of the Patients with Cervical Disorder (목의 기능장애 환자들에게 SNAGs기법과 바이오피드백 훈련이 통합적 고유수용성 감각과 목의 기능에 미치는 효과)

  • Lee, Eun Sang
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.1
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    • pp.284-290
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    • 2020
  • This study was undertaken to determine the effects of SNAGs (sustained natural apophyseal glides) and visual convergence biofeedback on the proprioception and neck disability of patients with chronic neck dysfunction. A total of 31 patients with neck dysfunction were assigned to either SNAGs (n = 16) or biofeedback (n = 15). The groups were assessed for proprioception and neck disability, before and after the intervention. The SNAGs were performed using belt with flexion, extension and right-left rotation, whereas biofeedback training included visual feedback training with deep neck flexor. Intervention was implemented for 20 minutes, twice a week for 4 weeks. Biofeedback training a showed significant effect on the joint position sense (left and right rotation) as compared to the SNAGs group (p< 0.05), whereas neck disability index was significantly effective for SNAGs (p< 0.05). Ed. Notes: The previous statement lacked clarity. I have suggested the edit as per my understanding. Please review and revise appropriately, if required. Therefore, the SNAGs technique is effective for neck function, and biofeedback training is a positive intervention method for enhancing the proprioceptive sensation. In future studies on patients with neck pain, it may be possible to select an intervention method based on the characteristics of the disease.

Experimental Study for Characteristics of Assessment of Neural Networks for Structural Damage Detection (구조물의 손상평가용 신경망의 특성평가에 관한 실험적 연구)

  • Oh, Ju-Won;Heo, Gwang-Hee;Jung, Eui-Tae
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.14 no.5
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    • pp.179-186
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    • 2010
  • When a structure is damaged, its dynamic responses (natural frequency, acceleration, strain) are found to be changed. The ANN(Artificial Neural Network) damage-assesment method is that some measured dynamic signals from the structural changing dynamic responses are applied to ANN to assess the structural damage. Although there have been some studies on a certain typical cases so far, it is rare to find studies about the characteristics of the ANN damage-assesment method or about its applicability, its strength and weakness. So this study researches on the characteristics of ANN damage assesment method and on a problem in application of the various dynamic responses to ANN. What the ANN damage assessment method usually does in past researches is to teach an ANN by using some response signals obtained from damaged structures under one kind of excitations and to identify the locations and the extents of damage of same structures under the same excitations. However, the excitations inflicted on the structures are not always the same. Thus this study experiments whether a ANN which is trained using the same excitations is able to identify the damage when different excitations inflict. All response signals are obtained from experimental models.

Health effects on workers and actual exposure of VOCs in the nail shops (네일샵 종사자의 휘발성유기화합물 노출실태와 건강에 미치는 영향)

  • Kim, Nan-Hee;Min, Kyoung-Woo;Cho, Gwang-Woon;Seo, Dong-Ju;Im, Kyeong-Hun;Jeung, Won-Sam;Cho, Young-Gwan;Yang, Jin-Seok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.27 no.1
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    • pp.59-69
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    • 2017
  • Objectives: The objective of this study is to evaluate the exposure of VOCs and effects of the chemicals on the nail technicians whose works in a nail shop. Methods: For four month from May to August in 2016, we measured twenty-two kinds of VOCs in ten nail shops and carried out health examinations on thirty-four workers in there. Results: The TVOC concentration in indoor air of nail shops is $0.487mg/m^3$ at a minimum and $33.236mg/m^3$ at a maximum where it consists of 70.5% of Ketones, 25.4% of Alcohols, 2.6% of Esters, 0.8% of Aldehydes and 0.7% of Aromatics. The VOCs concentration during nail art works shows an increase in average ratio 1.8 compared to the concentration of indoor air quality and also the concentration of Isopropanol rose with 3.2 of the highest ratio. The results of Spearman correlation between TVOC concentration in indoor air and environmental factor was like that has significance level of correlation(${\rho}$<0.05, r=0.682) in case of number of customers per day, but the other factors were not meaningful in correlation. Correlation between VOCs and medical check-up items was like that has positive significance level(${\rho}$<0.01, r=0.638) between isopropanol and GPT, but the others have not meaningful. The exposure level of VOCs was not exceed the criteria exposure level 1 of working environment measuring method which announced by labor ministry in all ten nail shop indoor air quality. Conclusions: In this study although it was not significant correlation between harmful substances and medical check-up items in the nail shop indoor air quality, it is necessary to do more ventilation and to install exhaust facilities because of existing high VOCs concentration in the nail shop indoor air.

Sphingosine 1-Phosphate-induced Signal Transduction in Cat Esophagus Smooth Muscle Cells

  • Song, Hyun Ju;Choi, Tai Sik;Chung, Fa Yong;Park, Sun Young;Ryu, Jung Soo;Woo, Jae Gwang;Min, Young Sil;Shin, Chang Yell;Sohn, Uy Dong
    • Molecules and Cells
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    • v.21 no.1
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    • pp.42-51
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    • 2006
  • We investigated the mechanism of contraction induced by S1P in esophageal smooth muscle cells. Western blot analysis demonstrated that $S1P_1$, $S1P_2$, $S1P_3$, and $S1P_5$ receptors existed in the cat esophagus. Only penetration of EDG-5 ($S1P_2$) antibody into permeabilized cells inhibited S1P-induced contraction. Pertussis toxin (PTX) also inhibited contraction, suggesting that it was mediated by $S1P_2$ receptors coupled to a PTXsensitive $G_i$ protein. Specific antibodies to $G_{i2}$, $G_q$ and $G_{\beta}$ inhibited contraction, implying that the S1P-induced contraction depends on PTX-insensitive $G_q$ and $G_{\beta}$ dimers as well as the PTX-sensitive $G_{i2}$. Contraction was not affected by the phospholipase $A_2$ inhibitor DEDA, or the PLD inhibitor ${\rho}$-chloromercuribenzoate, but it was abolished by the PLC inhibitor U73122. Incubation of permeabilized cells with $PLC{\beta}3$ antibody also inhibited contraction. Contraction involved the activation of a PKC pathway since it was affected by GF109203X and chelerythrine. Since $PKC{\varepsilon}$ antibody inhibited contraction, $PKC{\varepsilon}$ may be required. Preincubation of the muscle cells with the MEK inhibitor PD98059 blocked S1P-induced contraction, but the p38 MAP kinase inhibitor SB202190 did not. In addition, co-treatment of cells with GF 109203X and PD98059 did not have a synergistic effect, suggesting that these two kinases are involved in the same signaling pathway. Our data suggest that S1P-induced contraction in esophageal smooth muscle cells is mediated by $S1P_2$ receptors coupled to PTX-sensitive $G_{i2}$ proteins, and PTX-insensitive $G_q$ and $G_{\beta}$ proteins, and that the resulting activation of the $PLC{\beta}3$ and $PKC{\varepsilon}$ pathway leads to activation of a p44/p42 MAPK pathway.

A Technical Guide to Operational Regional Ocean Forecasting Systems in the Korea Hydrographic and Oceanographic Agency (I): Continuous Operation Strategy, Downloading External Data, and Error Notification (국립해양조사원 해양예측시스템 소개 (I): 현업 운영 전략, 외부 해양·기상 자료 내려 받기 및 오류 알림 기능)

  • BYUN, DO-SEONG;SEO, GWANG-HO;PARK, SE-YOUNG;JEONG, KWANG-YEONG;LEE, JOO YOUNG;CHOI, WON-JIN;SHIN, JAE-AM;CHOI, BYOUNG-JU
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.22 no.3
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    • pp.103-117
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    • 2017
  • This note provides technical guide on three issues associated with establishing and automatically running regional ocean forecasting systems: (1) a strategy for continuous production of hourly-interval three-day ocean forecast data, (2) the daily download of ocean and atmospheric forecasting data (i.e., HYCOM and NOAA/NCEP GFS data), which are provided by outside institutions and used as initial condition, surface forcing, and boundary data for regional ocean models, and (3) error notifications to numerical model managers through the Short Message Service (SMS). Guidance on dealing with these three issues is illustrated via solutions implemented by the Korea Hydrographic and Oceanographic Agency, since in embarking on this project we found that this procedural information was not readily available elsewhere. This technical guide is based on our experiences and lessons learned during the process of establishing and operating regional ocean forecasting systems for the East Sea and the Yellow and East China Seas over the 5 year period of 2012-2016. The fundamental approach and techniques outlined in this guide are of use to anyone wanting to establish an automatic regional and coastal ocean forecasting system.

Effect of Subacute Ruminal Acidosis on Plasma Concentrations of Lipopolysaccharide in Dairy Cattle (젖소에 있어 아급성제1위과산증(SARA)의 강도가 혈장 Lipopolysaccharide (LPS)의 농도에 미치는 효과)

  • Son, Hey In;Baek, Seong Gwang;Moon, Ju Yeon;Ahn, Eui-Young;Lee, Hyun-Jun;Son, Yong Suk
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.33 no.4
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    • pp.313-318
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    • 2013
  • A study was conducted to determine if subacute ruminal acidosis (SARA) induced by feeding high level of non-structural carbohydrates results in increases in lipopolysaccharides (LPS) of peripheral blood in dairy cattle. In this experiment four Holstein steers, two of which having ruminal canulae with indwelling probes placed for measuring long term pH changes, were alloted into two dietary treatments in a cross-over design, where an acidogenic diet (AD) was formulated by including high amount of non-structural carbohydrates (NSC) based on corn silage and corn flake as TMR ingredients. Data for ruminal pH change and plasma LPS concentration were compared against normal diet (ND) which contained grass hay as forage and low NSC ingredients. Feeding AD for more than 14 days to animals brought about a pH change as low as less than 5.8 for more than 4 hours, which made good contrast to ND fed animals. Decreased ruminal pH also had an effect on LPS concentrations which showed significantly higher level for AD compared with ND. Therefore, plasma LPS concentration may be used as an effective indicator to verify acidosis whether it is acute or chronic. Na-bentonite and Propylene glycol, which are frequently included in dairy TMR as additives, helped decrease ruminal pH by buffering and then ultimately alleviates SARA. Therefore, it could also be helpful to lower the occurrence of laminitis which is often caused by increased blood endotoxin (LPS) concentration.

The Unified Wireless Control System for the Vibration Control of Bridge (교량의 진동제어를 위한 통합 무선제어 시스템)

  • Heo, Gwang Hee;Kim, Chung Gil;Oh, Ju Won
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.16 no.2
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    • pp.65-74
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    • 2012
  • This paper aimed at the development of a unified wireless control system in order to control various forms of vibration of bridges. This unified wireless control system unified all different systems each of which functioned for difference purpose such as measurement, analysis, judgement, and control of data acquired from the movement of structure. It was designed to control structures with feedback which was returned according to each different situation after analyzing various signals measured about the structure. In this system, every information in each step from measurement to control was wirelessly transmitted to its central system so that a manager was able to effectively monitor the whole process. Just for the case when any system control need to intervene occurred, a graph user interface was designed for better access. In order to evaluate its basic performance, an experiment was carried out to see how signal input and output were done by comparing its results with those of a wired system. On the basis of the experiment, a vibration control experiment was performed on a model of cable-stayed bridge to see if the unified wireless control system worked well in realtime. This was carried out under four conditions, and the graph and quantitative result under each condition were compared each other. All experiments proved that the unified wireless control system functioned as well as the wired one in terms of its basic performance and vibration control.

A Study Regarding Measurements of Bacterial Contamination Levels in Radiology Room Equipment (방사선과 촬영실 장비의 세균오염도 측정)

  • Choi, Eun-Jin;Song, Hyeon-Je;Dong, Kyung-Rae;Kim, Chang-Bok;Ryu, Jae-Kwang;Kwak, Jong-Gil
    • Journal of Radiation Industry
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    • v.11 no.1
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    • pp.1-6
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    • 2017
  • Reported some level of bacteria in areas that are well made contact in Radiology imaging room evaluate the importance of cleanliness in the hospital management of equipment to check for the presence of pathogenic bacteria. Gwang-ju and Jeol-la city and medium-sized hospitals in the material with a cotton swab and rub evenly Radiology selection cassette, a handle, Apron of the imaging apparatus having the most contact with patients from July 2016 to August 2016 as a target in place and special studios 6, and saline solution will placed in a test tube containing. The swab sample was diluted 1,000 times, you can see the bacteria and the intestinal bacterial selective medium Trypticase Soy Agar (TSA), Muller-Hinton Agar (MHA), Eosin-Methylene Blue (EMB), ENDO(BD, NJ, USA) then incubated smear to. In the incubator (incubator, SANYO, Japan) was observed after incubation of bacteria and counting the total number of bacteria also Colonies (colony) suspected intestinal bacteria were isolated and cultured on KIA medium (BD, NJ, USA). As a result, it was found that this came Gram positive Coccus A hospital handle the F hospital, from the C Gram positive Coccus cassette and handle the F hospital. The striking yellow coloring Staphylococcus aureus 110 agar (STA 110) in the medium sample, but it is suspected staphylococcal Coccus to the final identification in the laboratory is not a single specimen of the two samples from Gram positive Coccus biochemical identification Identification Kit is an API could not, it was thought to be non-Staphylococcus aureus was cultured on blood agar suggesting that (BAP) blood of dance. Dynamic tests were conducted biochemical API kit of the two samples were identified from Gram positive Coccus bacteria Escherichia coli (E. coli) is F hospital cassette was confirmed Eenterobacter cloaca in A hospital possession. Did not aggregate O-26, O-111, O-157 and the serum test was conducted in the laboratory from the E. coli F cassette hospital.