• Journal of Periodontal and Implant Science
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• v.28 no.3
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• pp.431-451
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• 1998

4 beagle dogs aged over one and half years and weighed 15 to 16 Kg were utilized in this study. Experimental dehiscent defects were made in the mandibular edentulous area after removal of lower premolar. e-PTFE membrane resorbable membrane, and PDGF-BB-loaded resorbable membrane were covered at the dehiscent defects around the dental implants respectively. Animal was sacrificed at 1, 2, 3 months respectively. Non-decalicifed specimens were made and mutiple-stained for light microscopic study. The results were as follows: 1. Dehiscent defects around the implant installed in the beagle dog were an excellent defect model for studying guided bone regeneration. 2. Fibroblasts penetrated into expanded-PTFE membrane was observed and inflammatory cell infiltration was also observed around the membrane. 3. Resorbable membrane was degradaded and resorbed at 1 month after application to the dehiscent defect. Though multinucleated giant cells were observed adjacent to the membrane, that had no reverse effect on the boe regeneration. 4. PDGF-BB-Ioaded resorbable membrane was same capability as the resorbable membrane and e-PTFE membrane in the guided bone regeneration. 5. PDGF-BB-Ioaded resorbable membrane-applied site was better than resorbable membrane-applied site in the speed and maturity of bone formation. Within the above results, it was suggested that PDGF-BB-Ioaded resorbable membrane might have same bone regeneration capacity as nonresorbable membrane in the dehisced implant of the beagle dog and potentiality to use in human subjects.

• Journal of Korean Neurosurgical Society
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• v.65 no.4
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• pp.572-581
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• 2022

Objective : Compared to microscopes, exoscopes have advantages in field-depth, ergonomics, and educational value. Exoscopes are especially well-poised for adaptation into fluorescence-guided surgery (FGS) due to their excitation source, light path, and image processing capabilities. We evaluated the feasibility of near-infrared FGS using a 3-dimensional (3D), 4 K exoscope with near-infrared fluorescence imaging capability. We then compared it to the most sensitive, commercially-available near-infrared exoscope system (3D and 960 p). In-vitro and intraoperative comparisons were performed. Methods : Serial dilutions of indocyanine-green (1-2000 ㎍/mL) were imaged with the 3D, 4 K Olympus Orbeye (system 1) and the 3D, 960 p VisionSense Iridium (system 2). Near-infrared sensitivity was calculated using signal-to-background ratios (SBRs). In addition, three patients with brain tumors were administered indocyanine-green and imaged with system 1, with two also imaged with system 2 for comparison. Results : Systems 1 and 2 detected near-infrared fluorescence from indocyanine green concentrations of >250 ㎍/L and >31.3 ㎍/L, respectively. Intraoperatively, system 1 visualized strong near-infrared fluorescence from two, strongly gadolinium-enhancing meningiomas (SBR=2.4, 1.7). The high-resolution, bright images were sufficient for the surgeon to appreciate the underlying anatomy in the near-infrared mode. However, system 1 was not able to visualize fluorescence from a weakly-enhancing intraparenchymal metastasis. In contrast, system 2 successfully visualized both the meningioma and the metastasis but lacked high resolution stereopsis. Conclusion : Three-dimensional exoscope systems provide an alternative visualization platform for both standard microsurgery and near-infrared fluorescent guided surgery. However, when tumor fluorescence is weak (i.e., low fluorophore uptake, deep tumors), highly sensitive near-infrared visualization systems may be required.

• Journal of Sensor Science and Technology
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• v.18 no.5
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• pp.365-371
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• 2009

In this study, we have fabricated a fiber-optic pH sensor which is composed of a light source, plastic optical fibers and a spectrometer. As an indicator, a phenol red is used, and a pH liquid solution is prepared by mixing of phenol red and various kinds of pH buffer solutions in these experiments. The emitting light from a light source is guided by plastic optical fibers to the pH liquid solution, and the optical characteristic of a light is changed in the pH liquid solution according to its color change. Therefore, we have measured the intensities and wavelength shifts of the modulated lights, which are changed due to the color variations of phenol red at different pH values, by using of a spectrometer for spectral analysis. Also, the relationships between the pH values of liquid solutions and the optical properties of modulated light according to the change of color of phenol red are obtained.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2004.10a
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• pp.263-268
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• 2004

In the present study, a Nd;YAG Laser (pulse type) was used to emit ultrasonic signals to a test material. In addition, a total ultrasonic investigation system was designed by adopting a Fabry-Perot interferometer, which receives ultrasonic signals without any contact. For non-destructive test SM45C, which contains some flaws was used as a test material. Because it is easy to align light beam in receiver, and the length of the light beam does not change much even if convex mirror leans towards one side, confocal Fabry-Perot interferometer, which has stable frequency, and PI control are used to correct interfered and unstable signals from temperature, fluctuation and time shift of laser frequency. Stable signals are always obtained by the feedback of PI circuit signals in the confocal Fabry-Perot interferometer. The type, size and position of flaws inside the test material were examined by achieving the stabilization of an interferometer. This study presented a useful method, which could quantitatively investigate the fault of objects by using a Fabry-Perot interferometer.

• Journal of Sensor Science and Technology
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• v.14 no.4
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• pp.244-249
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• 2005

In this study, radiation sensor tips are fabricated for remote sensing of X or gamma ray with inorganic scintillators and plastic optical fiber. The visible range of light from the inorganic scintillator that is generated by radiation source is guided by the plastic optical fiber and is measured by optical detector and power-meter. Two kinds of sensor tips are designed and fabricated such as film type and powder type. Many kinds of inorganic scintillators are used to fabricate both sensor tips, and the different wavelength of emitting lights from them are measured to determine the optimal inorganic scintillator which has maximum light output. As a radiation source X-ray generator and Ir-192 are selected to test a performance of sensor tip. It is expected that the fiber-optic radiation sensor is widely used in nuclear industry and medical applications due to its special characteristics such as good flexibility, easy in processing, long lengths and no interference to electro magnetic field.

• Biomolecules & Therapeutics
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• v.18 no.2
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• pp.191-196
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• 2010

In the course of screening for antioxidant compounds by measuring the radical scavenging effect on 1,1-diphenyl- 2-picrylhydrazyl (DPPH), a total extract of the twigs of Stewartia koreana (Theaceae) was found to show potent antioxidant activity. Subsequent activity-guided fractionation of the methanolic extract led to the isolation of six phenolic compounds, ampelopsin (1), catechin (2), proanthocyanidin-A2 (3), fraxin (4), (2R, 3R)-taxifolin-3-${\beta}$-D-glucopyranoside (5), and (2S, 3S)-taxifolin-3-${\beta}$-D-glucopyranoside (6), as active principles. Their structures were elucidated by spectroscopic studies. Compounds 1-6 were isolated for the first time from this plant. Among them, three compounds 1-3 showed the significant antioxidative effects on DPPH, and riboflavin originated superoxide quenching activity. In riboflavin-nitrobluetetrazolium (NBT)-light system, compound 1 showed better superoxide quenching activity than vitamin C.

• Biomolecules & Therapeutics
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• v.17 no.4
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• pp.412-417
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• 2009

In the course of screening for antioxidant compounds by measuring the radical scavenging effect on DPPH (1,1-diphenyl- 2-picrylhydrazyl), a total extract of the twigs of Vitex rotundifolia (Verbenaceae) was found to show potent antioxidant activity. Subsequent activity-guided fractionation of the methanolic extract led to the isolation of three iridoid compounds, 10-O-vanilloylaucubin (1), 10-O-p-hydroxybenzoylaucubin (2) and aucubin (3), two C-glycoside flavones, vitexin (4) and orientin (5), and a quinic acid derivative, 3,4-di-O-caffeoylquinic acid (6). Their structures were elucidated by spectroscopic studies. Among them, compounds 5 and 6 showed the significant antioxidative effects on DPPH free radical scavenging test. In riboflavin-NBT-light and xanthine-NBT-xanthine oxidase systems, compounds 5 and 6 exhibited the formation of the blue formazan in a dose-dependent manner. Compounds 5 and 6 showed better superoxide quenching activities than vitamin C.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.20 no.2
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• pp.1-7
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• 2006

A light guided plate coupled with the micro Fresnel lens array(MFTA) is designed to improve the efficiency of the LCD backlight unit. Blazed Frenel lens and binary multi-level Fresnel lens are adapted for the MFLA. This type of MFLA can replace the prism sheet and diffuser sheet which are used for the conventional type of the LCD backlight unit. The luminance and uniformity are calculated to verify the performance of the MFLA type LCD backlight unit.

• International Journal of Safety
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• v.11 no.2
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• pp.1-4
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• 2012

The falling accidents have increased in the structure and heavy industries. Therefore, a various falling prevention systems with safety block and lanyard have been supplied in order to prevent falling accidents and acquire the long life and cost down for the maintenance. However, there are not the reliable and domestic the falling prevention system until now. Almost systems were imported from U.S.A, Japan, U.K and Germany. The structural safety of the imported safety block is satisfied sufficiently, but it has heavy weight due to the cover with the aluminum and thickness. So, many workers are not feeling themselves. Thus, the aim of this work is to develop a commercial safety block that has a light weight and strength. And the cost efficiency of the system and safety for workers also will be improved remarkably.

• Proceedings of the Korea Multimedia Society Conference
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• 2012.05a
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• pp.26-27
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• 2012

Reflection considered as the view disturbing noise in optical systems, such as stereo camera in autonomous vehicles especially in night. Reflection caused by the street light or due to rainwater under adverse weather conditions. A blur image detected by the camera that results in wrong guidance to vehicle for detecting its track. A vehicle guidance approach through stereo vision can be same in day and night time. However it cannot be guided with same image analysis due to diverse illumination conditions. We develop the technique that shows its efficacy with illustrations of reflection removal off the camera lens and vehicle tracking control.