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Effect of Green Tea on the Anti-Duodenal Ulcer in Cysteamine- Administrated Rats (녹차추출액이 Cysteamine투여 흰쥐의 항십이지장궤양에 미치는 영향)

  • 최성희;김순희;이병호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.4
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    • pp.374-380
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    • 1993
  • Effect of green tea extract, on duodenal ulceration was studied in male Sprague Dawley rats treated with cysteamine, a drug, which causes duodenal ulcers in experimental animal. As a result, in the proximal duodenum, a significant decrease of ulceration was detected twenty four hours after cysteamine injection in rats raised in green tea extract for 63days. Special reference to duodenal alkaline phosphatase activity was measured in mucosal homogenates. In control rats raised in tap water Riven saline, significant decrease was observed in proximal duodenal alkaline phosphataes activity. The decrease effect seems site specific, since the enzyme in the distal duodenum remains. Moreover the effect cysteamine in control rats alkaline phosphatase is specific, because, in rats raised in green tea extracts did not show significant change in activity. It is suggested that green tea extract acts in ideal properties as an anti-duodenal ulcer agent.

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Water Quality Management of Kyung-an River Basin (경안천 유역의 수환경 관리방안)

  • Kim, Jin-Ho;Lee, Jong-Sik;Kim, Won-Il;Jung, Goo-Bok;Yun, Sun-Gang;Kwun, Soon-Kuk
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2002.10a
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    • pp.469-472
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    • 2002
  • This study was conducted to show how to manage the water quality of Kyung-an river. The water quality and hydrologic data were obtained at the main river and branch streams in Marc $h{\sim}April$ 1998. First of all, we surveyed the contribution of branches for the pollution of water quality at Kyung-an river. It was in order of Kongiam(25.5%)>Yong-in Pollutant Treatment Complex (15.26%)^gt;Shin-won(13.99%)>Buen(11.86%)>Yangji(8.68%)>Yooun(7.43%)>Kwang-ju Pollution Treatment Complex(5.50%)>Osan(5.04%). The hydrological model using mass balance and BOD reduction formula suggested that if the quality of water Yoo-un and Shinn-won stream (branch streams of Kyung-an River) which is lowest in the basin is controlled adequately and outlet water from Yong-in pollutant treatment complex is adequately treated, the quality of Kyung-an river will be improved by 90% compared to current level.

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Study On The Midwater Trawl Available in the Korean Waters - 1 . Attitude and Opening Opening Efficiency of Otter Board - (한국 근해에 있어서의 중층 트로올의 연구 - 1 . 전개판의 동작상태의 전개성능 -)

  • 이병기
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.22 no.4
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    • pp.41-48
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    • 1986
  • To investigate the midwater trawl gear available for the Korean near sea trawlers, the authors carried out a field experiment on the attitude and the opening efficiency of the otter board with the Pusan 404 (160GT, 750ps), a training ship of National Fisheries University of Pusan. The experimental trawl gear was designed to be operable by the ship and the otter board was made of single iron plate with 12% camber ratio. The special-prepared potentiometric angle detector was used for determining the attitude, and the 50 KHz fish finder for the opening between the otter boards. The results obtained can be summarized as follows: 1. The angle of attack varied by moving the towing point on the towing plate of the otter board. It showed 33 to 36 degrees when the point was set at the outmost position, 25 to 31 degrees at the middle position and 19 to 30 degrees at the inmost position, with a decreasing tendency according to the increase of towing speed in each cases. 2. The heel of the otter board always occured inwards, increasing slightly according to the increase of towing speed. 3. The tilt of the otter board always occured outwards, increasing slightly according to the move of the towing point inwards, and decreasing slightly according to the increase of towing speed. 4. The opening between otter boards showed the largest value when the towing point was set at the outmost position.

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MOLECULAR CLONING OF CHICKEN INTERFERON-GAMMA (닭 인터페론 유전자의 클로닝에 관한 연구)

  • ;Hyun Lillehoj
    • Proceedings of the Korea Society of Poultry Science Conference
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    • 1999.11a
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    • pp.34-50
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    • 1999
  • A cDNA encoding chicken interferon-gamma (chIFN-${\gamma}$) was amplified from P34, a CD4$^{+}$ T-cell hybridoma by reverse transcription-polymerase chain reaction (RT-PCR) and cloned into pUC18. THe sequences of cloned PCR products were determined to confirm the correct cloning. Using this cDNA as probe, chicken genomic library from White Leghorn spleen was screened. Phage clones harboring chicken interferon-gamma (chIFN-${\gamma}$) were isolated and their genomic structure elucidated. The chIFN-${\gamma}$ contains 4 exons and 3 introns spanning over 14 kb, and follows the GT/AG rule for correct splicing at the exon/intron boundaries. The four exons encode 41, 26, 57 and 40 amino acids, respectively, suggesting that the overall structure of IFN-${\gamma}$ is evolutionairly conserved in mammalian and avian species. The 5’-untranslated region and signal sequences are located in exon 1. Several AT-rich sequences located in the fourth exon may indicate a role in mRNA turnover. The 5’-flanking region contains sequences homologous to the potential binding sites for the mammalian transcription factors, activator protein-1(AP-1) activator protein-2(AP-2) cAMP-response element binding protein(CREB), activating transcription factor(ATF), GATA-binding fator(GATA), upstream stimulating factor(USF), This suggests that the mechanisms underlying transcriptional regulation of chicken and mammalian IFN-${\gamma}$ genes may be similar.r.

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A Plausible Method for the Diagnosis of Genetic Disorders Using Full Length cDNA

  • Hur, Hyang-Suk;Lee, Young-Won;Park, Hyoung-Woo;Kim, Myoung-Hee
    • Biomedical Science Letters
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    • v.7 no.1
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    • pp.1-5
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    • 2001
  • A cDNA of coagulation Factor IX gene has been screened from the $\lambda$gt11 human fetal liver cDNA library, and used to construct a 2.8-kb full length cDNA after recombining with the N-terminal fragment from pTZ-FIX. Human genomic DNA was isolated, digested with the restriction endonucleases, TaqI, EcoRI, and HindIII, and Southern hybridization was performed using the full length factor IX cDNA as a probe. The hybridized bands generated by the restriction endonucleases were the followings: TaqI, 0.3, 1.0, 1.6, 1.8, 2.7, 3.7, and 5.3 kb bands; EcoRI, 1.8, 4.8, 4.9, 5.5, 6.8, and 12.6 kb bands; HindIII, 4.1, 4.4, 5.2, 5.8, 7.6, and 12.5 kb bands. When the Southern bands were physically mapped along the genome, about 50-kb continuous region harboring almost all of the genomic region of Factor Ⅸ gene was covered. These results suggest a possibility of using an exonal cDNA probe to diagnose abnormalities including large deletions, insertions, and rearrangements along the genome, if there is any.

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Effect of Vanes on Flow Distribution in a Diffuser Type Recuperator Header (디퓨저 타입 레큐퍼레이터 헤더에서 유동분배에 미치는 베인의 영향)

  • Jeong Young-Jun;Kim Seo-Young;Kim Kwang-Ho;Kwak Jae-Su;Kang Byung-Ha
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.18 no.10
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    • pp.819-825
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    • 2006
  • In a SOFC/GT (solid oxide fuel cell/gas turbine) hybrid power generation system, the recuperator is an indispensible component to enhance system performance. Since the expansion ratio to the recuperator core is very large, generally, the effective header design to distribute the flow uniformly before entering the core is crucial to guarantee the required performance. In the present study, we focus on the design of a diffuser type recuperator header with a 90 degree turn inlet port. To reduce the flow separation and recirculation flows, multiple horizontal vanes are used. The number of horizontal vanes is varied from 0 to 24. The air flow velocity is measured at 40 points just behind the core outlet by using a hot wire anemometer. Then, the flow non-uniformity is evaluated from the measured flow velocity. The experimental results showed that inlet air velocity did not effect on relative flow non-uniformity. According to increasing the number of horizontal vanes, flow non-uniformity reduced about $40{\sim}50%$ than without using horizontal vanes.

Forecast of geomagnetic storm using coronal mass ejection and solar wind condition near Earth

  • Kim, Rok-Soon;Park, Young-Deuk;Moon, Yong-Jae
    • The Bulletin of The Korean Astronomical Society
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    • v.38 no.1
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    • pp.63.1-63.1
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    • 2013
  • To improve the forecast capability of geomagnetic storms, we consider the real time solar and near Earth conditions together, since the characteristics of CMEs can be modified during their transit from the Sun to the Earth, and the geomagnetic storms may be directly affected by not only solar events but also near Earth interplanetary conditions. Using 55 CME-Dst pairs associated with M- and X-class solar flares, which have clearly identifiable source regions during 1997 to 2003, we confirm that the peak values of negative magnetic field Bz and duskward electric field Ey prior to Dst minimum are strongly related with Dst index. We suggest the solar wind criteria (Bz<-5 nT or Ey>3 mV/m for t>2 hr) for moderate storm less than -50 nT by modifying the criteria for intense storms less than -100 nT proposed by Gonzalez and Tsurutani (GT, 1987). As the results, 90% (28/31) of the storms are correctly forecasted by our criteria. For 15 exceptional events that are incorrectly forecasted by only CME parameters, 12 cases (80%) can be properly forecasted by solar wind criteria. When we applying CME and solar wind conditions together, all geomagnetic storms (Dst<-50 nT) are correctly forecasted. Our results show that, the storm forecast capability of the 2~3 days advanced warning based on CME parameters can be improved by combining with the urgent warning based on the near Earth solar wind condition.

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Boarding Environment of Training Ship KAYA to the Noise during the Voyage (실습선 가야호의 항해 중 선내 소음에 대한 승선환경)

  • Kim, Min-Son;Shin, Hyeon-Ok;Kim, Min-Seok;Hwang, Bo-Kyu
    • Journal of Fisheries and Marine Sciences Education
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    • v.22 no.2
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    • pp.218-230
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    • 2010
  • This study was conducted to determine the effect of the noise level on the boarding environment in a stern trawl ship, KAYA(GT: 1,737 tons, Pukyong National University). We measured the noise level at a working, an accommodation and a teaching area, and an engine space on January 9, 2010 while the KAYA was sailing on a liner sea route. At the working area, the ranges of the noise rating number(NRN) and the NRN determination frequency(FNRN) were from 44 to 73 and from 1000 to 2000Hz, respectively. The results were generally satisfied the criteria of the International Maritime Organization(IMO). The noise level at the area, except the radio room(w2), was exceeded the criteria(50dB(A)) for the efficient studying and working. The noise level at the engine control room and the machine workshop was respectively exceeded 1.2dB and 9.5dB than the criteria caused the conversation disturbance (70dB(A)). At the accommodation, NRN and FNRN were from 49 to 54 and from 1000 to 4000Hz, respectively. The noise level was below the criteria of IMO, but above 40dB(A) caused the sleep disturbance. At the teaching area, NRN and FNRN were from 44 to 63 and from 500 to 2000Hz, respectively. The noise level was exceeded than the criteria(50dB(A)) for the efficient studying. At the engine space, NRN and FNRN were from 95 to 100 and from 2000 to 4000Hz, respectively. The noise level was above the criteria of IMO(90dB(A)) for the residence, while it was not exceeded 110dB(A) for the transient.

Performance Evaluation of U-net Deep Learning Model for Noise Reduction according to Various Hyper Parameters in Lung CT Images (폐 CT 영상에서의 노이즈 감소를 위한 U-net 딥러닝 모델의 다양한 학습 파라미터 적용에 따른 성능 평가)

  • Min-Gwan Lee;Chanrok Park
    • Journal of the Korean Society of Radiology
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    • v.17 no.5
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    • pp.709-715
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    • 2023
  • In this study, the performance evaluation of image quality for noise reduction was implemented using the U-net deep learning architecture in computed tomography (CT) images. In order to generate input data, the Gaussian noise was applied to ground truth (GT) data, and datasets were consisted of 8:1:1 ratio of train, validation, and test sets among 1300 CT images. The Adagrad, Adam, and AdamW were used as optimizer function, and 10, 50 and 100 times for number of epochs were applied. In addition, learning rates of 0.01, 0.001, and 0.0001 were applied using the U-net deep learning model to compare the output image quality. To analyze the quantitative values, the peak signal to noise ratio (PSNR) and coefficient of variation (COV) were calculated. Based on the results, deep learning model was useful for noise reduction. We suggested that optimized hyper parameters for noise reduction in CT images were AdamW optimizer function, 100 times number of epochs and 0.0001 learning rates.

REPLACEMENT OF POSTERIOR RESTORATIONS (구치부 수복물의 재수복에 관한 연구)

  • Kim, Ji-Young;Choi, Kyoung-Kyu;Park, Sang-Jin
    • Restorative Dentistry and Endodontics
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    • v.31 no.6
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    • pp.460-469
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    • 2006
  • This article complies a survey on the replacement of the posterior restorations and accesses possible factors that influence the replacement of posterior restorations. The data was collected from patients that visited department of conservative dentistry from Dec 1st 2003, to Sep 3rd 2004. Teeth was restricted to posterior permanent teeth. 9 dentists recorded age, gender of patients, tooth location, cavity farm and restorative material. They rated marginal adaptation, anatomic form, secondary caries of old restoration by modified Ryge criteria system. The statistical analysis was performed with Chi square test (p < 0.05) for replacement ratio according to patients, tooth factor and One way ANOVA was performed for comparison of old restoration according to restorative material. The results were as follows; 1. The female (62%) was statistically higher ratio than the male (38%). 2. The distribution of replacement case according to age, the rate of replacement was in descending order, 20's (38.3%), 40's (16.8%), 30's (15.9%), 10's (11.1%), 50's (9.2%), 60's (8.7%). 3. The rate of replacement was 88% for molar and 12% for premolar (p $gt; 0.05). 4. The rate of replacement was 39% for maxillar and 61% for mandible (p $gt; 0.05). 5. The material of restorations was amalgam (69%), gold inlay (17%), composite resin (13%). 6. In rating system by modified Ryge criteria system on margin adaptation, there was statistically significant difference between amalgam and gold inlay. But on anatomic form and caries, there was no statistically significant difference among the material of restorations.