• Biomedical Science Letters
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• v.3 no.2
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• pp.71-76
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• 1997

To develop a promising alkylating agents for anti-cervical cancer chemotherapy, five mitosene analogues were synthesized. Despite the potentiality of better cytotoxicity on solid tumor cells as opposed to that on rapidly-doubled leukemic cells, there have been no reports on the inhibition of the cervical cancer cell line by mitosene analogues. The present experiment was designed to investigate whether mitosene analogues can effectively inhibit the cellular proliferation of cervical cancer cells by using an in vitro chemosensitivty system. The mitosene analogues displayed a potent cytotoxic effect on the tested cervical cancer cell lines. Among the analogues, (22) compound gave the best inhibitory effect on SiHa tumor colonies formation. These data indicate that mitosene analogues can effectively inhibit the growth of cervical cancer cells in vitro.

• The Plant Pathology Journal
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• v.34 no.2
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• pp.126-138
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• 2018

Rice blast caused by Magnaporthe oryzae is a major disease. In the present study, we aimed to identify and evaluate the novel bacterial isolates from rice rhizosphere for biocontrol of M. oryzae pathogen. Sixty bacterial strains from the rice plant's rhizosphere were tested for their biocontrol activity against M. oryzae under in vitro and in vivo. Among them, B. amyloliquefaciens had significant high activity against the pathogen. The least disease severity and highest germination were recorded in seeds treated with B. amyloliquefaciens UASBR9 (0.96 and 98.00%) compared to untreated control (3.43 and 95.00%, respectively) under in vivo condition. These isolates had high activity of enzymes in relation to growth promoting activity upon challenge inoculation of the pathogen. The potential strains were identified based on 16S rRNA gene sequencing and dominance of these particular genes were associated in Bacillus strains. These strains were also confirmed for the presence of antimicrobial peptide biosynthetic genes viz., srfAA (surfactin), fenD (fengycin), spaS (subtilin), and ituC (iturin) related to secondary metabolite production (e.g., AMPs). Overall, the results suggested that application of potential bacterial strains like B. amyloliquefaciens UASBR9 not only helps in control of the biological suppression of one of the most devastating rice pathogens, M. grisea but also increases plant growth along with a reduction in application of toxic chemical pesticides.

• Korean Journal of Agricultural Science
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• v.19 no.1
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• pp.115-127
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• 1992

Purpose of this study is to classify the main industrial function by region using the factor analysis. Identified regions, Yesan-Kun area consisted of 12 Myon(towns) selected as a case study, would be conducive to establishing rural town planning reflecting their industrial characteristics. Major findings are summarized as follows. First, population of Yesan-Kun has been decreased at about 1.0% annually for the period 1970~1990, which may not meet the basic condition of sustainable regional growth. Second, economy of Yesan area, which mainly has been dependent upon the agriculture, are lagged behind because of lack of specialized manufacturing sector. Third, particularly West and East part of the region has been underdeveloped in spite of their potentiality mainly due to insufficient network of road. Based on fator analysis which classify the zones by the characteristics of industry, following developmental directions are suggested. - Yesan-Eup with a factor score of 2.85 in secondary and tertiary industry, which means functioning as a rural center should be developed to provide the residential people with basic service. - Ducksan-Myon with 2.93 factor score in tour industry is recommended to formulate leisure complex by utilizing its abundant tour resources. - Sapkyo-Eup, Goduck-Myon, Sinam-Myon, Oga-Myon Areas functioning as agricultural industry, are suggested to foster as zones specialized for the cultivation of crops and fruits. - Kwangsi-Myon and Bongsan-Myon neighboring other counties is likely to be affected by other regions' economy. These regions should be developed in association with other regions' economic circumstances. - Daeheung-Myon, Daesool-Myon and Sinyang-Myon areas, which are located southern part of Yesan County, is examined to be relatively underdeveloped area. So there are needs to make a special planning for the balanced growth of these regions.

• Journal of Embryo Transfer
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• v.28 no.4
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• pp.325-335
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• 2013

The study was set for one year to measure the effects of concentrate supplementation on reproductive performances and semen quality in indigenous rams. The study was conducted at the Department of Surgery and Obstetrics, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh during the period from May 2011 to April 2012. Forteen ram lambs (4~5 months) were randomly divided into two equal groups (n=7); supplemented vs control. The animals of control group were maintained on natural grazing. Along with natural grazing the supplemented group was on supplemented feeding. The concentrate supplementation (Wheat bran, Crushed maize, Soy bean meal, Fish meal, DCP powder, Vitamin mineral premix, Salt) was provided @ 300 g/head /day to the supplemented group. Body weight, scrotal circumference, BCS and libido index were measured weekly. Age, body weight and scrotal circumference at puberty were recorded. Semen was collected once in a weak using artificial vagina and chilled at $5^{\circ}C$ for 48h for evaluation. Concentrate supplementation did not influence (p>0.05) body condition score, age, weight, scrotal circumference at puberty and libido index. Final body weight (kg), growth rate (g/d), scrotal circumference (cm) and scrotal growth rate (mm/15d) were significantly (p<0.05) higher in supplemented group of rams compared to control. Volume, concentration, motility and membrane potentiality of spermatozoa were varied significantly (p<0.05) in supplemented and control groups. However, density, mass motility, viability and sperm with normal acrosome, midpiece and tail were not differed insignificantly (p>0.05) in different observation times. It was concluded that concentrate supplementation with free grazing improved weight and scrotal circumference gain and semen production with increased quality in indigenous ram.

• Korean Journal of Food Science and Technology
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• v.35 no.6
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• pp.1182-1187
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• 2003

This study was performed to evaluate the potentiality of Reynoutria elliptica Migo., being used as a folk remedy and a herb medicine for urethritis, cystitis, etc., on growth inhibition of Helicobacter pylori which is known as the ulcerogenic pathogen. The minimum inhibitory concentration (MIC) value of methanol extract from Reynoutria elliptica Migo, was determined to be 120 ppm for H. pylori and urease activity derived from H. pylori was inhibited over 80% by the extract at 2 mg/mL in urea broth. Among various solvent fraction of the methanol extract, the hexane fraction showed a significant inhibitory effect on the growth of H. pylori reducing both its growth and urease activity. Scanning and transmission electron micrographs of H. pylori treated with the methanol extract at 2 mg/mL for 3 hr showed that the cell walls and membranes were disrupted so that the cytoplasmic components were leaked from the body. These results suggest that Reynoutria elliptica Migo. possesses a therapeutic potential on the gastric disease caused by H. pylori.

• Korean Journal of Plant Resources
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• v.22 no.4
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• pp.304-311
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• 2009

This study was conducted to develop functional sprout vegetables with antioxidant effects using seeds of Arctium lappa. The seeds germinated vigorously under light at $25^{\circ}C$, reaching germination rate of 82% within 4 days. Germinated seeds were placed under darkness at various temperatures to force growth in length, and it was demonatrated that $20^{\circ}C$ was optimum temperature. Greening treatment reduced growth in length, but promoted growth of cotyledons. Harvested A. lappa sprout vegetables maintained freshness longer at $10^{\circ}C$, rather than $4^{\circ}C$. Ventilation holes in storage containers had no effects on storage periods. Antioxidant activity of vegetable that received greening treatment for 1-3 days was investigated, and it was shown that free radical scavenging effects and ferrous ion chelating effects was higher than those of commercially available brocoli, cauliflower, pea and bean sprout. Contents of total polyphenol and flavonoid were also higher, especially by 3 day greening. The longer the treatment, the more the inhibition on peroxidation of linoleic acid. Sprout vegetable of A. lappa had higher antioxidant activity compared with adult plant. In conclusion, sprout vegetable of A. lappa has great potentiality for use as one of sprout vegetables.

• Journal of Periodontal and Implant Science
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• v.26 no.2
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• pp.396-413
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• 1996

Current acceptable methods for promoting periodontal regeneration are based on removal of diseased soft tissue. root treatment, guided tissue regeneration, introduction of new graft materials and biological mediators. Insulin-like growth factor-I(IGF-I) and Platelet-derived growth factor-BB(PDGF-BB), the members of the polypeptuyde growth factor family have been reported as the biological mediators which regulate a variety cellular matrix biologic activities of wound healing process including the cell proliferation, migration and extracellular matrix synthesis.The purposes of this study is to evaluate the combination effects of IGF-I and PDGF-BB on the cellular activity of the periodontal ligament cells to act as a regeneration promoting agent of periodontal tissue. Human periodontal ligament cells were prepared from the first premolar tooth extracted for the orthodontic treatment and were cultured in DMEM containing 10% FBS at the $37^{\circ}C$, 5% CO2 incubator. Author measured the DNA synthetic activity, and total protein, collagen and noncollagenous protein synthetic activities according to the concentration of 10,100ng/ml IGF-I and1,10 ng/ml PDGF-BB in combination. The results were as follows: Significantly increased in the 1 ng/ml PDGF-BB alone compared to the 10 ng/ml PDGF-BB alone(P<0.01) and in the 1 ng/ml PDGF-BB and 10, 100ng/ml IGF-I in combination compared to the 1 ng/ml PDGF-BB alone(P<0.05, P<0.0l). The synthetic activity of the total protein and collagen is significantly increased like to the synthetic activity of the DNA(P<0.05). The synthetic activity of the noncollagenous protein is increased according to the concentration of IGF_I, but not statistically statistically significant(P>0.05). The percent of the collagen is significantly in the 1ng/ml PDGF-BB and 10ng/ml IGF-I in combination compared to the 1ng/ml PDGF-BB alone(P<0.05) and in the 10ng/ml IGF-I in combination compared to the 10ng/ml PDGF-BB alone(P<0.05). The synthetic activity of the DNA is In conclusions, the percent study shows that PDGF-BB and IGF-I in combination have a potentiality to enhance the DNA synthesis and the total protein and collagen synthesis of The periodontal ligament cells, especially it is more significant in the low concentration of PDGF-BB compared to the high one. Thus, the PDGF-BB and IGF-I in combination may have important roles in promotion of periodontal litgment healing, and consequently, may useful for clinical application in periodontal regenerative procedures.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.8 no.4
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• pp.23-31
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• 2005

Green spaces in cities were insufficient and decreased as artificial structures increase. Accordingly, greening rooftop space contributed to urban ecosystems as green space. Especially, since 2002 Seoul supported rooftop greening and introduced 'Ecology-area rates'. Thus rooftop greening had the potentiality of extension. This prepared the extensive rooftop greenings within planting-base for extensive management rooftop greening system to be easily popularized. The extensive rooftop greening conducted from 1997-2005 reported that soil depth was 8cm and soil mixtures were 5 types. And plant were Crysanthemum zawaskii var. latilobum, Aster hayatae, Crysanthemum zawaskii herb. ssp. coreanum, Sedum sarmentosum, Sedum rotundifolium, Sedum oryzifolium, Sedum takemensis, Sedum middendorffianum, Sedum telerium var. purpureum, Sedum spectabile, Carypteris incana, Dianthus superbus, Hosta minor. As a result, for nine years after the modular type rooftop greening established, survival plants were Sedum takemensis, Sedum sarmentosum, Sedum spectabile, Sedum middendorffianum, Carypteris incana, Crysanthemum zawaskii var. latilobum, Sedum telerium var. purpureum, Sedum rotundifolium, Dianthus superbus. Also effect of greening was possibled soil depth 8cm. And growth of plants from 1997 to 2005 were fine on two soil mixtures of 'perlite+peatmoss+vermicompost+moisturizer' and 'perlite+moisturizer+bark(mulching)'. Invasive plants are Ixeris dentata Nakai, Ixeris chinensis var. strigosa, Youngia sonchifolia, Eragrostis ferruginea, Aster pilosus Willd., Ixeris japonica Nakai, Valpia myuros, and Setaria viridis. In conclusion, selection of suitable native plants was possible extensive management rooftop greening with effect of continuous greening. The extensive rooftop greening were lightweight and simple preparation without management and can popularize readily.

• Journal of The Korean Society of Grassland and Forage Science
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• v.17 no.2
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• pp.117-122
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• 1997

This experiment was conducted to evaluate the forage yield and quality and the possibility to provide Festulolium bmunii(Festuca pratensis $Huds{\times}Lolium$ mult~jlotum Lam.) as forage source in Korea. The Festuloliurn braunii were harvested at boot, heading and anthesis stage, respectively. The field trials were performed 6om 1994 to 1996 at the forage experimental field, College of agriculture, Chunpam National University. The results obtained were summarized as follows: 1. The date of boot, heading and anthesis stage of Festulolium bmunii observed in Taejon were May 12, May 23 and June 1 in 1995, and June 1, June 4 and June 9 in 1996, respectively. Winter survival percentage of Festulolium bmunii war ranged 6om 96% to 98% and summer survival percentage were 75-86%. It would suggest that Festulolium brawlii persisted well in the aspect of overwintering, while it wasn' t widely adapted to drought and high temperature in Taejon regions. 2. The CP content and DMD of Festulolium bmunii tended to decline as the growth stage advanced. The CP content and DMD of Festulolium bmunii were high at the boot stage and those at the anthesis stage were low. But fiber contents at the boot stage were lower than those at anthesis stage(P< 0.05). The yields of the DM and DDM with advancing the growing stage tended to increase, while there was no difference in the CPDM yields among stages. On the otherhand, the yields of DM and DDM at the anthesis stage were the highest (P< 0.05), but there was no difference in CPDM yield among stages. Based on the results mentioned above, it is suggested that Festulolium b m n i i has a possibility to use until the anthesis stage under the cutting regimes and that it has a potentiality to provide one of a good forage sources. %'ifqqiZ 43q *(College of Agriculture, Chungnam National Un~versity, Taejon 305-764, Korea)

• The Journal of the Korea Contents Association
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• v.17 no.7
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• pp.371-383
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• 2017

The aim of this paper is to investigate adjusting process of trade-off relationship between economic growth and income distribution in China which is established by mixed with social and market-oriented economic systems. The characteristic nature of social welfare index in urban and rural regions in China is examined by employing principal component analysis. Empirical evidences reveal that unlike national wide or urban region, the increases of income contribute to improve social well-being in rural region, but not social welfare index. Accordingly, it can be said that although social well-being in rural region seems to be harmful because of weakly organized social welfare index, the potentiality exists to improve social well-being by increased income. Taken all together, the results signifies that the mixed economic system such as China might distribute its increased income appropriately, however, the distributional system is hardly operated to improve social welfare index. And thus the distributional system has to be amended to enhance social well-being in China.